Panax quinquefolium L.

• Index
• Plant Species
• Metabolite list (18)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Panax quinquefolium L.
Genus	Panax
Family	Araliaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Panax
Linked NCBI taxonomy ID	4053
Linked level	genus

Family

Family in NCBI taxonomy	Araliaceae
ID	4050

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (18)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003518	Ginsenoside Re	CHEMBL510095	C049864	2 / 0 / 0	0 / 1	No. 11	No. 51
C00031118	Quinquenoside III					No. 11	No. 51
C00030841	Notoginsenoside E / (+)-Notoginsenoside E					No. 11	No. 51
C00030396	Gypenoside IV / Ginsenoside Rb3	CHEMBL449303 CHEMBL507688 CHEMBL452438	C044463	2 / 0 / 0		No. 11	No. 51
C00030391	Ginsenoside I					No. 11	No. 51
C00030268	Floralquinquenoside E					No. 11	No. 51
C00030390	Ginsenoside F3	CHEMBL1095004		2 / 0 / 0		No. 32	No. 51
C00030267	Floralquinquenoside D					No. 32	No. 51
C00030265	Floralquinquenoside B					No. 32	No. 51
C00030266	Floralquinquenoside C / (-)-Floralquinquenoside C					No. 32	No. 51
C00031119	Quinquenoside L9					No. 32	No. 51
C00030392	Ginsenoside Ia					No. 32	No. 51
C00003520	Ginsenoside Rg1	CHEMBL501637 CHEMBL1977916	C035054		5 / 6	No. 32	No. 51
C00030399	Panaxoside Rg2 / Ginsenoside Rg2	CHEMBL505747 CHEMBL1095005 CHEMBL1095006 CHEMBL1475728	C026474	5 / 0 / 0	7 / 2	No. 32	No. 51
C00024137	Pseudo-ginsenoside F11	CHEMBL509047 CHEMBL1899126 CHEMBL1899642		3 / 0 / 0		No. 32	No. 51
C00029447	24(S)-Pseudoginsenoside F11 / 24(S)-Pseudo-ginsenoside F11	CHEMBL509047 CHEMBL1899126 CHEMBL1899642		3 / 0 / 0		No. 32	No. 51
C00031100	Pseudoginsenoside RT5	CHEMBL447942	C487714			No. 99
C00030264	Floralquinquenoside A / (+)-Floralquinquenoside A					No. 99

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003518 C00030390 C00030396 C00030399	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003518 C00030390 C00030396 C00030399	0 / 0
O75496	Geminin	Unclassified protein	C00024137 C00029447 C00030399	0 / 0
P14735	Insulin-degrading enzyme	Enzyme	C00024137 C00029447	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00024137 C00029447	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00030399	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00030399	0 / 0

12 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
200186	CRTC2, TORC-2, TORC2	CREB regulated transcription coactivator 2	C00030399
92579	G6PC3, SCN4, UGRP	glucose 6 phosphatase, catalytic, 3 (EC:3.1.3.9)	C00030399
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00030399
8431	NR0B2, SHP, SHP1	nuclear receptor subfamily 0, group B, member 2	C00030399
5105	PCK1, PEPCK-C, PEPCK1, PEPCKC	phosphoenolpyruvate carboxykinase 1 (soluble) (EC:4.1.1.32)	C00030399
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00030399
6794	STK11, LKB1, PJS, hLKB1	serine/threonine kinase 11 (EC:2.7.11.1)	C00030399
898	CCNE1, CCNE	cyclin E1	C00003520
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00003520
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003520
3757	KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1	potassium voltage-gated channel, subfamily H (eag-related), member 2	C00003520
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00003520

Related Diseases

Diseases related to CTD interactions