KEGG   ORTHOLOGY: K03013Help
Entry
K03013                      KO                                     

Name
RPB5, POLR2E
Definition
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Pathway
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko01100  Metabolic pathways
ko03020  RNA polymerase
ko04623  Cytosolic DNA-sensing pathway
ko05016  Huntington's disease
ko05169  Epstein-Barr virus infection
Module
M00180  RNA polymerase II, eukaryotes
M00181  RNA polymerase III, eukaryotes
M00182  RNA polymerase I, eukaryotes
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
   00240 Pyrimidine metabolism
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
 Genetic Information Processing
  Transcription
   03020 RNA polymerase
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
 Organismal Systems
  Immune system
   04623 Cytosolic DNA-sensing pathway
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
 Human Diseases
  Neurodegenerative diseases
   05016 Huntington's disease
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
  Infectious diseases
   05169 Epstein-Barr virus infection
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   RNA polymerase
    M00180  RNA polymerase II, eukaryotes
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
    M00181  RNA polymerase III, eukaryotes
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
    M00182  RNA polymerase I, eukaryotes
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol I, II, III common subunits
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
  RNA polymerase III system
   RNA polymerase III
    Pol I, II, III common subunits
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
  RNA polymerase I system
   RNA polymerase I
    Pol I, II, III common subunits
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
BRITE hierarchy
Other DBs
RN: R00435 R00441 R00442 R00443
COG: COG2012
Genes
HSA: 5434(POLR2E)
PTR: 456359(POLR2E)
PPS: 100995503(POLR2E)
GGO: 101144214(POLR2E)
PON: 100173829(POLR2E)
NLE: 100601807(POLR2E)
MCC: 721178(POLR2E)
MCF: 101865584(POLR2E)
CSAB: 103233592(POLR2E)
RRO: 104671426(POLR2E)
RBB: 108537888(POLR2E)
CJC: 100393628(POLR2E)
SBQ: 101051807(POLR2E)
MMU: 66420(Polr2e)
RNO: 690966(Polr2e)
CGE: 100754513(Polr2e)
NGI: 103737342(Polr2e)
HGL: 101709249(Polr2e)
CCAN: 109693677(Polr2e)
TUP: 102501578(POLR2E)
CFA: 611859(POLR2E)
AML: 100476981(POLR2E)
UMR: 103681776(POLR2E)
ORO: 101377466(POLR2E)
FCA: 101095720(POLR2E)
PTG: 102950238(POLR2E)
AJU: 106978086(POLR2E)
BTA: 512971(POLR2E)
BOM: 102279426(POLR2E)
BIU: 109561974(POLR2E)
PHD: 102343842(POLR2E)
CHX: 102187213(POLR2E)
OAS: 101116826(POLR2E)
SSC: 100623333(POLR2E)
CFR: 102516640(POLR2E)
CDK: 105104119(POLR2E)
BACU: 103001195(POLR2E)
LVE: 103071766(POLR2E)
OOR: 101277900(POLR2E)
ECB: 100065431(POLR2E)
EPZ: 103544865(POLR2E) 103545717
EAI: 106834192(POLR2E)
MYB: 102238881(POLR2E)
MYD: 102764259(POLR2E)
HAI: 109390606(POLR2E)
RSS: 109443057 109453932(POLR2E)
PALE: 102877935(POLR2E)
LAV: 100674866(POLR2E)
TMU: 101355270
MDO: 100015794(POLR2E)
SHR: 100927834(POLR2E)
OAA: 100087192(POLR2E)
GGA: 420103(POLR2E)
MGP: 100539270(POLR2E)
CJO: 107325463(POLR2E)
ACYG: 106048192(POLR2E)
TGU: 100189945 100222301(POLR2E)
GFR: 102045201(POLR2E)
FAB: 101817569(POLR2E)
PHI: 102113148(POLR2E)
PMAJ: 107215548(POLR2E)
CCW: 104697062(POLR2E)
FPG: 101921128(POLR2E)
FCH: 102056021(POLR2E)
CLV: 102092010(POLR2E)
EGZ: 104127392(POLR2E)
AAM: 106493538(POLR2E)
ASN: 102379403(POLR2E)
AMJ: 102570813(POLR2E)
PSS: 102443501(POLR2E)
CMY: 102942937(POLR2E)
CPIC: 101945038(POLR2E)
PVT: 110072605(POLR2E)
PBI: 103062569(POLR2E)
GJA: 107107350(POLR2E)
XLA: 108696070 398968(polr2e.S)
XTR: 549227(polr2e)
NPR: 108789491(POLR2E)
DRE: 445170(polr2eb)
IPU: 100528214(polr2e)
AMEX: 103030076(polr2e)
TRU: 101073703(polr2e)
LCO: 104930510(polr2e)
NCC: 104948113(polr2e)
MZE: 101481657(polr2e)
OLA: 101160893(polr2e)
XMA: 102219457(polr2e)
PRET: 103463716(polr2e)
NFU: 107393346(polr2e)
CSEM: 103376763(polr2e)
LCF: 108879021(polr2e)
BPEC: 110174071(polr2e)
SASA: 106569462(RPAB1) 106573578(RPAB1)
ELS: 105011501(polr2e) 105022321
SFM: 108919890(polr2e)
LCM: 102365405(POLR2E)
CMK: 103189926(polr2e)
CIN: 100182874
SPU: 578317
APLC: 110977470
SKO: 100370922
DME: Dmel_CG11979(Rpb5)
DSI: Dsimw501_GD15257(Dsim_GD15257)
MDE: 101892048
AAG: 5574369
AME: 413110 551142(GB10998)
BIM: 100748620
BTER: 100650619
SOC: 105194466
AEC: 105148474
ACEP: 105619052
PBAR: 105428078
HST: 105181521
CFO: 105251888
LHU: 105670625
PGC: 109864206
NVI: 100115905
TCA: 664433
DPA: 109534835
NVL: 108566499
BMOR: 101744152
PMAC: 106716578
PRAP: 111000657
PXY: 105392149
API: 100158973
DNX: 107164723
ZNE: 110827350
FCD: 110861498
TUT: 107368911
CEL: CELE_H27M09.2(rpb-5)
CBR: CBG12745(Cbr-rpb-5)
CRG: 105330308
MYI: 110445162
OBI: 106874998
SHX: MS3_00822
ATH: AT2G41340(RPB5D) AT3G22320(NRPB5) AT3G54490(RPB5E) AT3G57080(NRPE5) AT5G57980(RPB5C)
LJA: Lj0g3v0102149.1(Lj0g3v0102149.1) Lj1g3v4159160.1(Lj1g3v4159160.1) Lj2g3v0812020.1(Lj2g3v0812020.1) Lj2g3v0813200.1(Lj2g3v0813200.1) Lj4g3v3113140.1(Lj4g3v3113140.1) Lj4g3v3113140.2(Lj4g3v3113140.2)
DOSA: Os01t0805800-01(Os01g0805800) Os04t0487300-01(Os04g0487300) Os11t0143400-00(Os11g0143400) Os12t0139500-01(Os12g0139500)
ATS: 109731909(LOC109731909) 109745722(LOC109745722) 109746010(LOC109746010) 109766283(LOC109766283) 109782662(LOC109782662) 109782663(LOC109782663)
ZMA: 100193880 100273250(pco088367b) 100273995
CRE: CHLREDRAFT_151082(RPB5)
MNG: MNEG_9076
APRO: F751_1971
SCE: YBR154C(RPB5)
ERC: Ecym_5335
KMX: KLMA_40224(RPB5)
NCS: NCAS_0I02370(NCAS0I02370)
NDI: NDAI_0A06960(NDAI0A06960)
TPF: TPHA_0M00690(TPHA0M00690)
TBL: TBLA_0F01160(TBLA0F01160)
TDL: TDEL_0D05090(TDEL0D05090)
KAF: KAFR_0G01400(KAFR0G01400)
PIC: PICST_53602(RPB5)
CAL: CAALFM_C112820CA(CaO19.6340)
CAUR: QG37_00136
NCR: NCU05305
NTE: NEUTE1DRAFT145772(NEUTE1DRAFT_145772)
MGR: MGG_06083
MAW: MAC_01379
MAJ: MAA_06406
CMT: CCM_03021
MBE: MBM_01719
ANI: AN0752.2
ANG: ANI_1_1616014(An01g11950)
ABE: ARB_00066
TVE: TRV_01312
PTE: PTT_16482
SPO: SPAC23C4.15(rpb5)
CNE: CNA07710
CNB: CNBA7540
ABP: AGABI1DRAFT114282(AGABI1DRAFT_114282)
ABV: AGABI2DRAFT191302(AGABI2DRAFT_191302)
MGL: MGL_3685
DDI: DDB_G0291636(rpb5)
EHI: EHI_142090(200.t00008)
PYO: PY17X_1142000(PY02779)
PCB: PCHAS_114010(PC000476.03.0)
TAN: TA10195
TPV: TP04_0911
BBO: BBOV_III009920(17.m07860)
CPV: cgd2_980
TGO: TGME49_240590(POLR2E)
SMIN: v1.2.005765.t1(symbB.v1.2.005765.t1)
TPS: THAPSDRAFT_268816(RPB5)
SPAR: SPRG_05117
BARC: AOA65_1693(rpoH)
BARB: AOA66_1727(rpoH)
VG: 18266059(pv_31) 19738591(007R) 30523590(BQ3484_79)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
PMID:9852112
  Authors
Kershnar E, Wu SY, Chiang CM
  Title
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
  Journal
J Biol Chem 273:34444-53 (1998)
DOI:10.1074/jbc.273.51.34444
  Sequence
[hsa:5434]
Reference
  Authors
Engel C, Sainsbury S, Cheung AC, Kostrewa D, Cramer P
  Title
RNA polymerase I structure and transcription regulation.
  Journal
Nature 502:650-5 (2013)
DOI:10.1038/nature12712
  Sequence
[sce:YBR154C]

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