KEGG ORTHOLOGY: K10803

ORTHOLOGY: K10803

Entry

K10803                      KO

Symbol

XRCC1

Name

DNA-repair protein XRCC1

Pathway

map03410

Base excision repair

Disease

H01891

Autosomal recessive spinocerebellar ataxias

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    K10803  XRCC1; DNA-repair protein XRCC1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10803  XRCC1; DNA-repair protein XRCC1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Short Patch-BER factors
     K10803  XRCC1; DNA-repair protein XRCC1

Genes

HSA:	7515(XRCC1)

PTR:	456094(XRCC1)

PPS:	100968357(XRCC1)

GGO:	101126292(XRCC1)

PON:	100458994(XRCC1)

PPYG:

129019911(XRCC1)

NLE:	100580597(XRCC1)

HMH:	116480030(XRCC1)

SSYN:

129466174(XRCC1)

MCC:	711457(XRCC1)

MCF:	102135778(XRCC1)

MTHB:

126942952

MNI:	105463850(XRCC1)

CSAB:

103234789(XRCC1)

CATY:

105572277(XRCC1)

PANU:

100998954(XRCC1)

TGE:	112612654(XRCC1)

MLEU:

105552154(XRCC1)

RRO:	104669458(XRCC1) 115898748

RBB:	108538045(XRCC1)

TFN:	117081478 117091919(XRCC1)

PTEH:

111525236(XRCC1)

CANG:

105526943(XRCC1)

CJC:	100390129(XRCC1)

SBQ:	101038846(XRCC1)

CIMI:

108285271(XRCC1)

ANAN:

105707148(XRCC1)

CSYR:

103252632(XRCC1)

MMUR:

105869458(XRCC1)

LCAT:

123624023(XRCC1)

PCOQ:

105817656(XRCC1)

OGA:	100951296(XRCC1)

MMU:	22594(Xrcc1)

MCAL:

110298827(Xrcc1)

MPAH:

110336452(Xrcc1)

RNO:	84495(Xrcc1)

MCOC:

116101809(Xrcc1)

ANU:	117694550(Xrcc1)

MUN:	110539766(Xrcc1)

CGE:	100689414(Xrcc1)

MAUA:

101829223(Xrcc1)

PROB:

127238572(Xrcc1)

PLEU:

114709839(Xrcc1)

MORG:

121449411(Xrcc1)

MFOT:

126491421

AAMP:

119822015(Xrcc1)

NGI:	103749151(Xrcc1)

HGL:	101701146(Xrcc1)

CPOC:

100727471(Xrcc1)

CCAN:

109691885(Xrcc1) 109699870 109702249

DORD:

105998125(Xrcc1)

DSP:	122097424(Xrcc1)

PLOP:

125368020(Xrcc1)

NCAR:

124967553

MMMA:

107151393(Xrcc1)

OCU:

100350130

OPI:	101526200(XRCC1)

TUP:	102495918(XRCC1)

GVR:	103589065(XRCC1)

CFA:	476447(XRCC1)

CLUD:

112645369(XRCC1)

VVP:	112931248(XRCC1)

VLG:	121485226(XRCC1)

NPO:	129500560(XRCC1)

AML:	100469866(XRCC1)

UMR:	103657007(XRCC1)

UAH:	113243495(XRCC1)

UAR:	123777461(XRCC1)

ELK:

111139524

LLV:

125089607

MPUF:

101674659(XRCC1)

MNP:	132004772(XRCC1)

MLK:	131817854(XRCC1)

NVS:	122911991(XRCC1)

ORO:	101380128(XRCC1)

EJU:	114197123(XRCC1)

ZCA:	113935759(XRCC1)

MLX:	117998080(XRCC1)

NSU:	110572738(XRCC1)

LWW:	102748646(XRCC1)

FCA:	101091917(XRCC1)

PYU:	121018535(XRCC1)

PCOO:

112851343(XRCC1)

PBG:	122493946(XRCC1)

PVIV:

125153656(XRCC1)

LRUF:

124511062

PTG:	102966848(XRCC1)

PPAD:

109258003(XRCC1)

PUC:

125915236

AJU:

106973677

HHV:	120241308(XRCC1)

BTA:	616905(XRCC1)

BOM:	102273904(XRCC1)

BIU:	109572880(XRCC1)

BBUB:

102406558(XRCC1)

BBIS:

104997652(XRCC1)

CHX:	102183814(XRCC1)

OAS:	101106279(XRCC1)

BTAX:

128063330(XRCC1)

ODA:	120873267(XRCC1) 120876719

CCAD:

122421132(XRCC1)

MBEZ:

129546719(XRCC1)

SSC:	100519604(XRCC1)

CFR:	102515293(XRCC1)

CBAI:

105062474(XRCC1)

CDK:	105090267(XRCC1)

VPC:	102525880(XRCC1)

BACU:

103016368 103019064

BMUS:

118885485(XRCC1) 118885654

LVE:	103088384(XRCC1)

OOR:	101277432(XRCC1)

DLE:	111180788(XRCC1)

PCAD:

102996639(XRCC1)

PSIU:

116744422(XRCC1)

NASI:

112415360(XRCC1)

ECB:	100070201(XRCC1)

EPZ:	103550912(XRCC1)

EAI:	106848428(XRCC1)

MYB:	102264126(XRCC1)

MYD:	102771224(XRCC1)

MMYO:

118674450(XRCC1)

MLF:	102426027(XRCC1) 102427523

MDT:	132216790(XRCC1)

PKL:	118713935(XRCC1)

EFUS:

103301420(XRCC1)

MNA:	107542248(XRCC1)

DRO:	112312822(XRCC1)

AJM:	119054415(XRCC1)

PDIC:

114511044(XRCC1)

PHAS:

123823054(XRCC1)

MMF:	118639364(XRCC1)

PPAM:

129082830(XRCC1)

HAI:	109372805(XRCC1)

RFQ:	117035494(XRCC1)

PALE:

102885428(XRCC1)

PGIG:

120605228(XRCC1)

PVP:	105297380(XRCC1)

RAY:	107512298(XRCC1)

MJV:	108407777(XRCC1)

TOD:	119249416(XRCC1)

SARA:

101538418(XRCC1)

SETR:

126028289(XRCC1)

LAV:	100662169(XRCC1)

TMU:

101350165

ETF:	101656819(XRCC1)

DNM:	101428590(XRCC1)

SHR:	100919247(XRCC1)

AFZ:

127556406

PCW:	110219859(XRCC1)

TVP:	118837596(XRCC1)

OAA:	100086870(XRCC1)

GGA:	100857925(TRPC2L)

PCOC:

116233909

MGP:	100542455(XRCC1)

TPAI:

128074967(XNDC1N)

LMUT:

125696199(XNDC1N)

NMEL:

110391616(XRCC1)

ACYG:

106029430(XNDC1N)

CATA:

118259772(XNDC1N)

TGU:	116807149(XRCC1)

PRUF:

121354719

FAB:	101807741(XRCC1)

OMA:	130259216(XNDC1N)

PHI:	102114459(XRCC1)

CCW:

104686976

CBRC:

103613978(XRCC1)

ETL:	114059632 114072772

ZLE:

135441878

SVG:

106856597

HRT:	120749483(XNDC1N) 120766033

SATI:

136375213(XNDC1N)

FCH:

106631356

SHAB:

115603207(XRCC1) 115603638

TALA:

116962544

ACHC:

115353225

HLE:	104837507(XRCC1)

AGEN:

126048298

GCL:

127028683

NNI:	104011876(XRCC1)

RTD:	128903956(XRCC1) 128904907(XNDC1N)

AAM:	106483913(XRCC1)

AROW:

112961382(XRCC1)

DNE:	112993977(XRCC1)

SCAM:

104143304(XRCC1)

ASN:	102383592 102387972(XRCC1)

AMJ:	102563462(XRCC1) 106737986

CPOO:

109306854

GGN:	109303332(XRCC1)

PSS:	102461495(XRCC1)

CMY:	102932854(XRCC1) 119567187(XNDC1N)

CCAY:

125625578 125631429(XNDC1N)

DCC:	119847810(XRCC1)

CPIC:

101940435(XRCC1) 122172152

TST:	117869650(XRCC1) 117871350

CABI:

116832213 116834928(XRCC1)

MRV:	120390756(XRCC1) 120396051

ACS:	100561839(xrcc1)

ASAO:

132780161(XRCC1)

PVT:	110089613(XRCC1)

SUND:

121915344(XRCC1) 121925673

PBI:	103053968(XRCC1) 103062651

PMUR:

107293236(XRCC1)

CTIG:

120317612(XRCC1) 120320225

TSR:	106547858(XRCC1)

PGUT:

117676442(XNDC1N) 117677579 132712438(XRCC1)

APRI:

131199471(XNDC1N) 131204137(XRCC1)

PTEX:

113451413(XRCC1)

NSS:	113421184(XRCC1)

VKO:	123025833(XRCC1)

PMUA:

114595492 114603418(XRCC1)

PRAF:

128412225(XNDC1N) 128418377(XRCC1)

ZVI:	118085071 118086469(XRCC1)

HCG:	128332828(XRCC1) 128350196(XNDC1N)

GJA:	107112050(XRCC1) 107114328

STOW:

125432129(XNDC1N)

EMC:	129343549(XRCC1)

XLA:	108704966(xrcc1.S) 380403(xrcc1.L) 446884(xndc1.l)

XTR:	100380033(xrcc1) 100491855

NPR:	108785535(XRCC1)

RTEM:

120916402(XRCC1) 120928847

BBUF:

120991326(XRCC1) 120996586

BGAR:

122930561(XNDC1N) 122940281(XRCC1)

MUO:	115468331 115475689(XRCC1)

GSH:	117362180 117369224(XRCC1)

DRE:	445480(xrcc1) 550335(xndc1)

SRX:	107715430 107724767(xrcc1) 107733514 107737754

SANH:

107673334(xrcc1) 107677402 107684729

SGH:	107557048 107565304 107601957

CCAR:

109074996 109105499

CAUA:

113038444 113115784(xrcc1)

CGIB:

127975276 127985484

PTET:

122357998(xrcc1)

LROH:

127151909(xndc1) 127178943(xrcc1)

OMC:	131522353(xrcc1) 131528695(xndc1)

PPRM:

120471177(xrcc1) 120494748(zgc:110224)

RKG:	130091526(xrcc1) 130095350(xndc1)

MAMB:

125243420(xrcc1) 125252688(xndc1)

CIDE:

127497421 127503843

CERY:

137037265(xrcc1)

MASI:

127430902 127453118 127454540

TROS:

130558184(xrcc1) 130570515(xndc1)

TDW:	130433441(xrcc1)

MANU:

129424195(xndc1) 129448911(xrcc1)

IPU:

108278020

PHYP:

113541498(xrcc1)

SMEO:

124403735(xrcc1)

TFD:	113650797(xrcc1)

TVC:	132840380(xrcc1)

TRN:	134301378(xrcc1)

AMEX:

103035660(xndc1) 111188241(xrcc1)

CMAO:

118799009(xrcc1)

EEE:	113574424(xrcc1)

CHAR:

105901710(xrcc1)

TRU:	101066034 115250498

TFS:	130532279(xrcc1)

LCO:	104930278(xrcc1)

NCC:	104950328(xrcc1)

TBEN:

117468504(xrcc1)

CGOB:

115021832(xrcc1)

PGEO:

117461163(xrcc1)

GACU:

117562160(xrcc1)

EMAC:

134862090(xrcc1)

ELY:	117266281(xrcc1)

EFO:	125893349(xrcc1)

PLEP:

121946260(xrcc1)

SLUC:

116060498(xrcc1)

ECRA:

117946503(xrcc1)

ESP:	116691186(xrcc1)

PFLV:

114557550(xrcc1)

GAT:	120810922(xrcc1)

PPUG:

119198092(xrcc1)

AFB:	129109601(xrcc1)

CLUM:

117745340(xrcc1)

PSWI:

130213105(xrcc1)

MSAM:

119897220(xrcc1)

SCHU:

122881764(xrcc1)

CUD:	121514110(xrcc1)

ALAT:

119006740(xrcc1)

MZE:	101472637(xrcc1)

ONL:	100694354(xrcc1)

OAU:	116325131(xrcc1)

OLA:	101158723(xrcc1)

OML:	112143923(xrcc1)

CSAI:

133437765(xrcc1)

XMA:	102235919(xrcc1)

XCO:	114142191(xrcc1)

XHE:	116717690(xrcc1)

PRET:

103477880(xrcc1)

PFOR:

103139267(xrcc1)

PLAI:

106960481(xrcc1)

PMEI:

106917694(xrcc1)

GAF:	122830731(xrcc1)

PPRL:

129371009(xrcc1)

CVG:	107083576(xrcc1)

CTUL:

119797881(xrcc1)

GMU:	124866111(xrcc1)

NFU:	107379307(xrcc1)

KMR:	108240303(xrcc1)

ALIM:

106530063(xrcc1)

NWH:	119409894(xrcc1)

AOCE:

111572504(xrcc1)

MCEP:

125016874(xrcc1)

CSEM:

103388848(xrcc1)

POV:	109633541(xrcc1)

SSEN:

122762451

HHIP:

117777416(xrcc1)

HSP:	118113365(xrcc1)

PPLT:

128450139(xrcc1)

SMAU:

118308107(xrcc1)

LCF:

108899421

SDU:	111235825(xrcc1)

SLAL:

111654736(xrcc1)

XGL:	120784694(xrcc1)

HCQ:	109515356(xrcc1)

SSCV:

125975308

SBIA:

133500476(xrcc1)

PEE:	133402100(xrcc1)

PTAO:

133479763(xrcc1)

BPEC:

110168224(xrcc1)

MALB:

109954706(xrcc1)

BSPL:

114843440(xrcc1)

SJO:	128366043(xrcc1)

SASA:

106582635 106603393 106605164

STRU:

115154436 115177083 115177302

OTW:	112228643(zgc:110224) 112241572 112246164

OMY:	110488613 110516655 110533738(zgc:110224)

OGO:	123990643(xndc1) 123997638 124005444

ONE:	115105160 115135825 115141176

OKI:	109875621 109901752 109909610

OKE:	118364327 118367383 118390175(xndc1)

SALP:

111958857 111965187

SNH:	120030864 120048350 120057123(zgc:110224)

CCLU:

121561619 123484912

ELS:	105008516(xrcc1)

SFM:	108919203(xrcc1)

PKI:	111841727(xrcc1)

AANG:

118226937(xrcc1) 118236086(zgc:110224)

LOC:	102690712(xrcc1) 107076668

PSPA:

121298651 121302810(zgc:110224) 121304431

ARUT:

117433643 117434162

PSEX:

120540107(xrcc1)

LCM:	102364763(XRCC1)

HOC:	132833956(xrcc1)

PMRN:

116957495(XRCC1)

LRJ:	133339415 133347881(XRCC1)

BFO:	118416812 118423557

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG4208(XRCC1)

DER:

6550892

DSE:

6612418

DSI:	Dsimw501_GD16724(Dsim_GD16724)

DYA:	Dyak_GE16396

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11076

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

AOQ:

MDE:	101899315 131804392

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ003295 CpipJ_CPIJ011204 CpipJ_CPIJ012852 CpipJ_CPIJ020141

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105675700(XRCC1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213985

MJU:

VCD:

MCIX:

PMAC:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

HAW:

HZE:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM252910

FOC:	113202535 113210012 113214764

TPAL:

117641908 117642202 117651505

ZNE:	110833550 110838842

CSEC:

BROR:

IEL:

FCD:

DMK:

PVM:	113814454 113818909

PJA:	122259754 122265347

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:	135224648 135224649

HAZT:

108675457

EAF:

111709305

LSM:	121114871 121130309

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DFR:

CSCU:

CVS:	136985220(XRCC1)

PTEP:

107451548

ABRU:

129969241

UDV:

129227566

SDM:	118186075 118202968

LPOL:

106457401

PMEO:

129585714

TSP:

Tsp_08702

HRO:	HELRODRAFT_188891

LGI:	LOTGIDRAFT_123015 LOTGIDRAFT_139677

PVUL:

126830573

PCAN:

112560997 112568206

BGT:	106065399 106068386

GAE:	121367805 121386531

HRF:	124128756 124151013

HRJ:	124267040 124286579

CRG:	105337784 105343161

CANU:

128190363

CVN:	111135198 111135354

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:	106873284 106882291

OSN:	115221560 115229961

LJP:

135481274

LAK:	106162010 106174323 106174338

SMM:	Smp_074070.1

SHX:	MS3_00010581(XRCC1)

OVI:	T265_10980

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114523723 114528077

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_19032

AQU:	100638211 105316749

ATH:	AT1G80420(ATXRCC1)

ALY:

9325357

CRB:

17894725

CSAT:

104705100 104714337 104752481

EUS:	EUTSA_v10018735mg

BRP:

103853256

BNA:	106398475 125581658 125586126

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10025766mg

PVY:

MINC:

TCC:

GRA:

GHI:	107949576 107951899

GAB:

HSYR:

DZI:

EGR:

GMX:	100780160 100818448

GSJ:	114373645 114386683

PVU:	PHAVU_005G172600g

VRA:

VAR:

VUN:

VUM:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:	131624923 131648391

LJA:

130749475

ADU:

107484019

AIP:

107639224

AHF:	112743617 112797001

LANG:

109342839 109357973

PCIN:

129289768

QSA:	O6P43_018095

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:	110631970 110653833

MESC:

110612885

POP:

7490987

PEU:	105109648 105117536

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:	119990696 120010280

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107783037 107783778

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110698738 110703324

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:	4340098(xrcc1)

OBR:

OGL:

BDI:

ATS:

TDC:	119287805 119331481

TAES:

123087989 123151422 123166924

TUA:

125522568

LPER:

127311347

LRD:	124666786 124669021

SBI:

8070726

ZMA:

100283527

MFLO:

136521434 136527813 136530740

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	122018928 122023596

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

PPP:

MBR:	MONBRDRAFT_29749

SRE:	PTSG_12674

DDI:	DDB_G0275653(xrcc1)

DPP:	DICPUDRAFT_79761

DFA:	DFA_05940(xrcc1)

ACAN:

ACA1_374140

GTT:	GUITHDRAFT_100252(XRCC1) GUITHDRAFT_103430

NGR:	NAEGRDRAFT_47730

» show all

Reference

PMID:22392994

Authors

Han L, Mao W, Yu K

Title

X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining.

Journal

Proc Natl Acad Sci U S A 109:4604-8 (2012)
DOI:10.1073/pnas.1120743109

Sequence

[mmu:22594]

All links

Ontology (2)   
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Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (1725)   
   KEGG GENES (883)   
   KEGG MGENES (88)   
   RefGene (742)   
   OC (12)   
Literature (1)   
   PubMed (1)   
All databases (1731)   

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