KEGG ORTHOLOGY: K12875

ORTHOLOGY: K12875

Entry

K12875                      KO

Symbol

ACIN1, ACINUS

Name

apoptotic chromatin condensation inducer in the nucleus

Pathway

map03013

Nucleocytoplasmic transport

map03015

mRNA surveillance pathway

map03040

Spliceosome

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
  09122 Translation
   03013 Nucleocytoplasmic transport
    K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
   03015 mRNA surveillance pathway
    K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
   03041 Spliceosome
    K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    EJC complex
     K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
Spliceosome [BR:ko03041]
Complex C
  Other components
   EJC/TREX
    K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus

Other DBs

TC:

3.A.18.1

Genes

HSA:	22985(ACIN1)

PPS:	100982806(ACIN1)

GGO:	101130589(ACIN1)

PON:	100441233(ACIN1)

PPYG:

129012789(ACIN1)

NLE:	100594211(ACIN1)

HMH:	116484909(ACIN1)

SSYN:

129489343(ACIN1)

MCC:	713310(ACIN1)

MCF:	102140949(ACIN1)

MTHB:

126958233

CSAB:

103231461(ACIN1)

CATY:

105598779(ACIN1)

PANU:

100999586(ACIN1)

TGE:	112628264(ACIN1)

MLEU:

105547181(ACIN1)

RRO:	104674147(ACIN1)

RBB:	108523549(ACIN1)

TFN:	117069974(ACIN1)

PTEH:

111554763(ACIN1)

CANG:

105503775(ACIN1)

CJC:	100395500(ACIN1)

SBQ:	101035336(ACIN1)

CIMI:

108315267(ACIN1)

ANAN:

105727140(ACIN1)

CSYR:

103270259(ACIN1)

MMUR:

105864642(ACIN1)

LCAT:

123620402(ACIN1)

PCOQ:

105814431(ACIN1)

OGA:	100954259(ACIN1)

MMU:	56215(Acin1)

MCAL:

110309502(Acin1)

MPAH:

110325592(Acin1)

RNO:	305884(Acin1)

MCOC:

116085411(Acin1)

ANU:	117705352(Acin1)

MUN:	110550035(Acin1)

CGE:	100769875(Acin1)

MAUA:

101823959(Acin1)

PROB:

127230411(Acin1)

PLEU:

114708752(Acin1)

MORG:

121435114(Acin1)

MFOT:

126490913

AAMP:

119800513(Acin1)

NGI:	103739470(Acin1)

HGL:	101718648(Acin1)

CPOC:

100730104(Acin1)

CCAN:

109685665(Acin1)

DORD:

105992521(Acin1)

DSP:	122113476(Acin1)

PLOP:

125363466(Acin1)

NCAR:

124976053

MMMA:

107148070(Acin1)

OCU:

100338262

OPI:	101518701(ACIN1)

TUP:	102476145(ACIN1)

GVR:	103585567(ACIN1)

CFA:	480247(ACIN1)

CLUD:

112657770(ACIN1)

VVP:	112926505(ACIN1)

VLG:	121492894(ACIN1)

NPO:	129499404(ACIN1)

AML:	100470890(ACIN1)

UMR:	103681036(ACIN1)

UAH:	113246017(ACIN1)

UAR:	123795784(ACIN1)

ELK:

111140671

LLV:

125104869

MPUF:

101684042(ACIN1)

MNP:	131999801(ACIN1)

MLK:	131836352(ACIN1)

NVS:	122893375(ACIN1)

ORO:	101365802(ACIN1)

EJU:	114217969(ACIN1)

ZCA:	113908864(ACIN1)

MLX:	118003463(ACIN1)

NSU:	110585465(ACIN1)

LWW:	102731917(ACIN1)

FCA:	101092859(ACIN1)

PYU:	121031505(ACIN1)

PCOO:

112855142(ACIN1)

PBG:	122468884(ACIN1)

PVIV:

125167557(ACIN1)

LRUF:

124508821

PTG:	102967669(ACIN1)

PPAD:

109255034(ACIN1)

PUC:

125909693

AJU:

106988222

HHV:	120240438(ACIN1)

BTA:	534600(ACIN1)

BOM:	102277013(ACIN1)

BIU:	109564806(ACIN1)

BBUB:

102403177(ACIN1)

BBIS:

104982091(ACIN1)

CHX:	102182699(ACIN1)

OAS:	101122696(ACIN1)

BTAX:

128053743(ACIN1)

ODA:	120853426(ACIN1)

CCAD:

122443206(ACIN1)

MBEZ:

129562401(ACIN1)

SSC:	100156353(ACIN1)

CFR:	102516665(ACIN1)

CBAI:

105068839(ACIN1)

CDK:	105096982(ACIN1) 116153486

VPC:	102526511(ACIN1)

BACU:

103008173(ACIN1)

BMUS:

118889589(ACIN1)

LVE:	103086038(ACIN1)

OOR:	101280956(ACIN1)

DLE:	111164099(ACIN1)

PCAD:

102980214(ACIN1)

PSIU:

116747393(ACIN1)

NASI:

112397490(ACIN1)

ECB:	100055865(ACIN1)

EPZ:	103556737(ACIN1)

EAI:	106840647(ACIN1)

MYB:	102254655(ACIN1)

MYD:	102752916(ACIN1)

MMYO:

118679150(ACIN1)

MLF:	102420583(ACIN1)

MDT:	132240537(ACIN1)

PKL:	118725115(ACIN1)

EFUS:

103301518(ACIN1)

MNA:	107531656 107531699

DRO:	112301436(ACIN1)

SHON:

118980909(ACIN1)

AJM:	119037212(ACIN1)

PDIC:

114491536(ACIN1)

PHAS:

123820519(ACIN1)

MMF:	118623452(ACIN1)

PPAM:

129074131(ACIN1)

HAI:

109393669

RFQ:	117023853(ACIN1)

PALE:

102883827

PGIG:

120593648(ACIN1)

PVP:	105300533(ACIN1)

RAY:	107497999(ACIN1)

MJV:	108400011(ACIN1)

TOD:	119238918(ACIN1)

SARA:

101548842(ACIN1)

SETR:

126001347(ACIN1)

LAV:	100673527(ACIN1)

TMU:

101343564

ETF:	101663260(ACIN1)

DNM:	101413618(ACIN1)

MDO:	100030457 103092024

GAS:	123237991(ACIN1)

SHR:	100933439(ACIN1)

AFZ:

127551045

PCW:	110192412(ACIN1)

TVP:	118828442(ACIN1)

OAA:	103165410(ACIN1)

AFUL:

116501611(ACIN1)

PHI:

106628920

ASN:	102381515(ACIN1)

AMJ:	102574582(ACIN1)

CMY:	102930650(ACIN1)

CCAY:

125622086(ACIN1)

DCC:	119841752(ACIN1)

CPIC:

101933498(ACIN1)

CABI:

116838307(ACIN1)

MRV:	120380869(ACIN1)

ACS:	100554591(acin1)

ASAO:

132777636(ACIN1)

PVT:	110087816(ACIN1)

SUND:

121935444(ACIN1)

PBI:	103062346(ACIN1)

PMUR:

107294114(ACIN1)

CTIG:

120317997(ACIN1)

TSR:	106556311(ACIN1) 106556591

APRI:

131198817(ACIN1)

PTEX:

113448753(ACIN1) 113450251

NSS:	113422275(ACIN1) 113428254 113429199

VKO:	123018641(ACIN1)

PMUA:

114582334(ACIN1)

PRAF:

128400822(ACIN1)

ZVI:	118094413(ACIN1)

HCG:	128329316(ACIN1)

GJA:	107106145(ACIN1)

STOW:

125444417(ACIN1)

EMC:	129338310(ACIN1)

XLA:	733423(acin1.L) 734979(acin1.S)

XTR:	407918(acin1)

NPR:	108786742 108786764(ACIN1)

BGAR:

122923326(ACIN1)

MUO:	115458004(ACIN1)

GSH:	117350246(ACIN1)

DRE:	327495(acin1b) 368893(acin1a)

SRX:	107706346 107738206 107742278 107753932

SANH:

107668844 107668955 107691940 107694674

SGH:	107557984 107562517 107588150 107591382

CCAR:

109064681 109064682 109075854 109112277

CAUA:

113044984 113052127 113105709 113119896

CGIB:

127933289 127950593 127962707 128017134

PTET:

122348727(acin1b) 122358013(acin1a)

LROH:

127167998(acin1b) 127176132(acin1a)

OMC:	131520634(acin1a) 131544290(acin1b)

PPRM:

120462579(acin1b) 120465051(acin1a)

RKG:	130076185(acin1a) 130102664(acin1b)

MAMB:

125250962(acin1a) 125264487(acin1b)

CIDE:

127494033 127516639

CERY:

137003713(acin1a) 137030943(acin1b)

MASI:

127440625 127440762 127442317 127450309

TROS:

130551766(acin1b) 130554142(acin1a)

TDW:	130417201(acin1a) 130428917(acin1b)

MANU:

129440233(acin1b) 129441833(acin1a)

IPU:	108267949(acin1b)

IFU:	128610241(acin1b)

PHYP:

113539899(acin1)

SMEO:

124387262(acin1b)

TFD:	113663216(acin1b)

TVC:	132848834(acin1b)

TRN:	134312410(acin1b)

AMEX:

103024124(acin1b)

CMAO:

118826578(acin1b)

EEE:	113578280 113589191(acin1)

TRU:	101061384 101074005

TFS:	130523334(acin1b) 130539559(acin1a)

TNG:	GSTEN00015141G001 GSTEN00025881G001

LCO:	104927977 104932906

NCC:	104943187 104949277 104956584(acin1)

TBEN:

117488092(acin1b) 117488512(acin1a)

CGOB:

115023739

PGEO:

117462460(acin1a) 117463624(acin1b)

GACU:

117539237(acin1b) 117556616(acin1a)

EMAC:

134866053(acin1a) 134871836(acin1b)

ELY:	117246213(acin1b) 117272063(acin1a)

EFO:	125883650(acin1b) 125902856(acin1a)

PLEP:

121950884(acin1a) 121962335(acin1b)

SLUC:

116043337(acin1b)

ECRA:

117934696(acin1b) 117953857(acin1a)

ESP:	116698826 116706992

PFLV:

114545942 114565025

GAT:	120816301(acin1a) 120822554(acin1b)

PPUG:

119209153(acin1a) 119221764(acin1b)

AFB:	129089372(acin1a) 129093788(acin1b)

CLUM:

117746690(acin1a) 117747418(acin1b)

PSWI:

130197895(acin1a) 130211455(acin1b)

MSAM:

119902995(acin1a) 119911460(acin1b)

SCHU:

122869952(acin1b) 122886784(acin1a)

CUD:	121504276(acin1b) 121520498(acin1a)

ALAT:

119011019(acin1a) 119027151(acin1b)

MZE:	101464651 101466250(acin1)

ONL:	100712586 106097156

OAU:	116312340(acin1b) 116333775(acin1a)

OLA:	101170959 111949076(acin1)

OML:	112147161(acin1a) 112155912(acin1b)

CSAI:

133420100(acin1b) 133452984(acin1a)

XMA:	102217545 102237119

XCO:	114146494 114156802

XHE:	116721541 116732127

PRET:

103475989 103478881(acin1)

PFOR:

103138403 103145983

PLAI:

106934755(acin1) 106944744

PMEI:

106903830(acin1) 106918835

GAF:	122820057(acin1b) 122840718(acin1a)

PPRL:

129361708(acin1a) 129379389(acin1b)

CVG:	107087714(acin1) 107102485

CTUL:

119773421(acin1b) 119793336(acin1a)

GMU:	124869993(acin1a) 124881214(acin1b)

NFU:	107377177 107384246(acin1)

KMR:	108238627(acin1a) 108245921(acin1b)

ALIM:

106514892(acin1) 106517891 106526430 106535998

NWH:	119408940(acin1b) 119414988(acin1a)

AOCE:

111567476 111577976

MCEP:

125008075(acin1b) 125011305(acin1a)

CSEM:

103388267 103388655 103396595(acin1)

POV:	109640428(acin1) 109643374

SSEN:

122766139(acin1b) 122773775 122773856(acin1a)

HHIP:

117778946(acin1a) 117779291(acin1b)

HSP:	118102823(acin1b) 118117332(acin1a)

PPLT:

128429794(acin1b) 128454181(acin1a)

SMAU:

118287726(acin1b) 118310275(acin1a)

LCF:	108883933(acin1a) 108903047(acin1b)

SDU:	111223791 111235663

SLAL:

111647173 111647202 111666578

XGL:	120797162(acin1b) 120799031(acin1a)

HCQ:	109508424 109512778(acin1)

SSCV:

125971220

SBIA:

133494700(acin1b) 133510443(acin1a)

PEE:	133397609(acin1b) 133411424(acin1a)

PTAO:

133472888(acin1b) 133488549(acin1a)

BPEC:

110170375(acin1) 110171990 110172043

MALB:

109962613 109974410

BSPL:

114843895(acin1a) 114867524(acin1b)

SJO:	128369255(acin1a) 128384015(acin1b)

SASA:

106569440(acin1) 106577794 106600278 106608850

STRU:

115156445 115169486 115194396 115198400

OTW:	112214863 112226706(acin1a) 112235593(acin1b) 112259628 112260765

OMY:	110500490 110508482(acin1a) 110530602 110531633(acin1b)

OGO:	124008902(acin1b) 124009387 124014312 124041588(acin1a)

ONE:	115102779 115114677(acin1) 115133440 115137976

OKI:	109871745 109874898 109896968 109906432

OKE:	118368872(acin1b) 118392087 118395250 118401869(acin1a)

SALP:

111953219 111956624 111979289 112069116

SNH:	120020208(acin1a) 120030297(acin1b) 120049714 120056089

CCLU:

121572620 121581128(acin1a) 123482967

ELS:	105020563 105021555(acin1) 114830399

SFM:	108930936 108937851(acin1) 114911832

PKI:	111837706 111854537(acin1)

AANG:

118233485(acin1a)

PSPA:

121305238 121306841

ARUT:

117398134(acin1b) 117398757

LCM:	102353532(ACIN1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

DME:	Dmel_CG10473(Acn)

DER:

6549440

DSE:

6614635

DSI:	Dsimw501_GD24176(Dsim_GD24176)

DYA:	Dyak_GE13225

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI13075

DAZ:

DNV:

DHE:

DVI:

CCAT:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ004841

CPII:

CNS:

BCOO:

AME:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM463890

FOC:

TPAL:

ZNE:

CSEC:

DPX:	DAPPUDRAFT_259237

DMK:

DPZ:

PPOI:

VDE:

VJA:

DPTE:

DFR:

CSCU:

CVS:	136990311(Acn)

PTEP:

107451679

SDM:

118184613

CEL:	CELE_C43E11.1(acin-1)

NAI:	NECAME_01311

LOA:	LOAG_02896

HRO:	HELRODRAFT_182973

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:

SMM:	Smp_039490.1

OVI:	T265_04671

EGL:

LLON:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

HMG:

RES:

TAD:	TRIADDRAFT_55789

AQU:

ATH:

ALY:

CRB:

CSAT:

104716251 104720899 104729289

EUS:	EUTSA_v10024660mg

BRP:	103835104 103851344

BNA:	106361360 106363140 106439157 125577105

BOE:	106332671 106335122

RSZ:

108822503

THJ:	104807709 104824862

CPAP:

110826427

CIT:

102612499

CIC:	CICLE_v10025009mg

PVY:	116115017 116122646

MINC:

123198650 123222496

TCC:

18611632

GRA:	105763681 105784983 105787854

GHI:	107906954 107941967 107950385 107950386 107951672 107951674

GAB:	108466554 108466555 108478007

HSYR:

120122409 120165583 120195625

DZI:	111291891 111299836 111316944

EGR:

104418232

GMX:	100786288 100816245

GSJ:	114382681 114397730

PVU:	PHAVU_001G250000g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:	11408942 11439947

TPRA:

123903908 123903969 123919032

CAM:

101502466

PSAT:

127082853 127106309

VVO:	131603199 131641732 131661435

LJA:

130710293

ADU:	107469237 107480405

AIP:	107622560 107631117

AHF:	112715234 112733274 112783562 112791247

LANG:

109328401 109343649 109343650

PCIN:

129308642

QSA:	O6P43_023249 O6P43_030432

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103401693 103437612

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:	101213308 116406242

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:	110671011 110671012

MESC:

110629388 110630280

POP:	7456930 7477106

PEU:	105111866 105123838 105136072

PALZ:

118038603 118043544

JRE:	109010171 109013259

CILL:

CAVE:

QSU:

QLO:

TWL:	119995016 119998716 120013388

VVI:	100248897 100252593

VRI:	117906620 117917400

SLY:

101245055

SPEN:

107017631

SOT:	102581657 102582659

SSTN:

125857169 125857170

SDUL:

129902331 129904105

CANN:

107867564 107867565

LBB:	132627470 132627471

NTA:	107780879 107787584 107807454 107825767

NSY:	104222647 104239460

NTO:	104098804 104098806

NAU:	109243407 109243408

INI:	109149513 109185733

ITR:	116013355 116022195

SIND:

105176487

OEU:	111386794 111408895 111409077

EGT:

SSPL:

SMIL:

SHIS:

HAN:	110903685 110910921 110912098

ECAD:

122587133 122603456 122604536

LSV:	111882882 111906474

CCAV:

112515431 112515879

DCR:	108204286 108214537

CSIN:

114294196

RVL:	131298188 131302431

AEW:	130785006 130785115 130785736 130785743

BVG:

104895719

SOE:

110786143

CQI:	110682172 110718182

ATRI:

130820135

MOF:

131159773

NNU:	104600068 104605908

MING:

122073307 122078924

TSS:	122665716 122666582

PSOM:

113281762 113281774 113286927 113290482 113331838 113347478

OSA:	4332988 4343967

OBR:	102705892 102719029

OGL:	127766971 127779655

BDI:	100828438 100830765

ATS:	109756890 109781791

TDC:	119285768 119296092 119353729 119362907

TAES:

123044136 123052015 123086003 123091905 123097449 123187881

TUA:	125536180 125551691

LPER:

127332074 127332313

LRD:	124676246 124702537

SBI:

110431408

ZMA:	100381870 100502129 103635858

MFLO:

136529844 136530711 136550448

SITA:

101756757 101758731

SVS:	117838034 117845226

PVIR:

120652191 120661896 120693470

PHAI:

112874468 112882830

PDA:	103700797 103713319

EGU:	105041650 105048600

MUS:	103976716 103979203

ZOF:	121981710 121985578 122010300 122016612

DCT:

110110510

PEQ:

110033210

AOF:

109832652

MSIN:

131227063 131232618 131242198

NCOL:

116260382

ATR:	18422129 18427065 18436757

SMO:	SELMODRAFT_442865 SELMODRAFT_444007

PPP:	112286216 112292409

VCN:	VOLCADRAFT_98786

CSL:	COCSUDRAFT_65753

MBR:	MONBRDRAFT_31107

SRE:	PTSG_04833

DDI:	DDB_G0286261

DFA:

DFA_07562

» show all

Reference

PMID:10490026

Authors

Sahara S, Aoto M, Eguchi Y, Imamoto N, Yoneda Y, Tsujimoto Y

Title

Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation.

Journal

Nature 401:168-73 (1999)
DOI:10.1038/43678

Sequence

[hsa:22985]

Reference

PMID:16314458

Authors

Tange TO, Shibuya T, Jurica MS, Moore MJ

Title

Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.

Journal

RNA 11:1869-83 (2005)
DOI:10.1261/rna.2155905

Sequence

[hsa:22985]

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Ontology (4)   
   KEGG BRITE (3)   
   TC (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Gene (2722)   
   KEGG GENES (907)   
   KEGG MGENES (386)   
   RefGene (1414)   
   OC (15)   
Literature (2)   
   PubMed (2)   
All databases (2734)   

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