KEGG   Gekko japonicus (Schlegel's Japanese gecko): 107112263
Entry
107112263         CDS       T04299                                 
Symbol
ITCH
Name
(RefSeq) itchy E3 ubiquitin protein ligase
  KO
K05632  E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
Organism
gja  Gekko japonicus (Schlegel's Japanese gecko)
Pathway
gja04120  Ubiquitin mediated proteolysis
gja04144  Endocytosis
gja04330  Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:gja00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    107112263 (ITCH)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    107112263 (ITCH)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    107112263 (ITCH)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gja04131]
    107112263 (ITCH)
   04121 Ubiquitin system [BR:gja04121]
    107112263 (ITCH)
Enzymes [BR:gja01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     107112263 (ITCH)
Membrane trafficking [BR:gja04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    107112263 (ITCH)
Ubiquitin system [BR:gja04121]
 Ubiquitin ligases (E3)
  HECT type E3
   107112263 (ITCH)
SSDB
Motif
Pfam: HECT WW C2
Other DBs
NCBI-GeneID: 107112263
NCBI-ProteinID: XP_015268870
Position
Un
AA seq 887 aa
MDKVHEPSCGMAGNGSRSESVSGLTMKSQLQVTVISAKLKENKNKWFGPSPYVEVSVDGQ
SKKTEKCNNTNSPKWKQHLTVIVTPFSKLNFRVWSHQTLKTDVLLGSATLDVHETLKANN
MKLEEVIVNLLLVGDKEPVEVIGDLSVCLDGLQVDPELLTNGDAPSVRSPTQNDGSRAKN
ETRSNAHSSENTEASASKESRVANGSDGPLIANGGFKPARPPRPSRPPPPTPRRPSAPSA
CTNGPSSASTEPEGAGIGLVPTSTANVGAEQNIEMAPSGATIPASAALTTPPISRQVQPV
TPVSQPHHTVTQGPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGR
IYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDFTQNKEFDP
LGPLPHGWEKRTDSNGRVYFVNHNTRITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYF
VDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVSRKT
LFEDSFQQIMSLSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAG
KDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKD
LESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPDGSDILVTEENKEE
YIKLVAEWRLSRGVEEQTQAFFEGFNEILPQTYLQYFDAKELEVLLCGMQEIDLTDWQRH
TIYRHYTRTSKQIVWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCI
EKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq 2664 nt   +upstreamnt  +downstreamnt
atggacaaggttcatgaaccttcctgtggtatggctggtaatgggtcaagatcagagtct
gtcagtggactaactatgaaatcacaacttcaggtcactgttatttctgcaaagttgaaa
gagaacaaaaacaaatggtttggacctagtccttatgtggaagtatcagtagatggacag
tcaaagaagacagaaaaatgcaacaatacaaatagtccaaaatggaaacaacatcttaca
gtaattgtcactcctttcagcaaactgaattttcgtgtatggagtcaccagacgttgaag
actgatgtcttattgggaagtgccactctagatgttcatgagacgctcaaagcaaacaat
atgaagcttgaagaagtgatcgtgaacttgctccttgttggtgacaaagaaccagttgaa
gtgattggagacttgtctgtttgtttagatggcttgcaagtagatcctgagctgctaact
aatggggatgctccaagtgtaagaagtcccacacagaatgatggctccagagcaaaaaat
gaaacaaggagtaatgcacacagttctgaaaacactgaggcttctgcatctaaagaaagc
agggtagctaatggcagtgatggtccattaattgcaaatggaggttttaagcccgctaga
ccacccagaccttctcgaccacctccgcccactccacgaaggccctctgctccatctgca
tgtaccaatgggccatcatctgcatccacagaaccagaaggggctggtataggattggtg
ccaacatcaactgcaaatgttggggcagaacaaaacattgaaatggcaccatcaggagca
actatacctgcatcagctgctttgaccacaccgccaatatccagacaagttcagccagta
actcctgtatcacagccacatcatacagtcactcaaggtcctcttccacctggttgggag
caaagagtggaccaacatggtcgagtgtattatgtagatcatgttgaaaaaagaactacg
tgggacaggccagagcctcttcctccaggttgggaacgcagagttgacaacatgggaagg
atctattatgtcgaccactttaccagaacgacaacctggcagcggccaactttggaatct
gtccggaattatgaacaatggcagcttcaacgcagccagcttcaaggagctatgcaacag
tttaatcagagattcatatatgggaatcaagacttcacacagaacaaagaatttgatcct
cttggtcccctgccgcacggatgggaaaagagaacagacagcaatggcagggtatatttt
gtaaaccataatactcgtatcacacagtgggaagatcctagaaatcaaggtcagttgaat
gaaaaacctttaccagagggctgggagatgagattcactgtggatggaattccatatttt
gttgatcacaatagaagaacaacaacatatatagatcctcgtactggaaaatctgctcta
gacaatggacctcagatagcctatgttcgtgatttcaaagcaaaagtccagtatttccgg
ttttggtgtcagcaactcgctatgccccagcacataaaaatcacagtgagcagaaagaca
ttgtttgaagactcctttcaacagataatgagcctcagccctcaggatttacgaagacgc
ttgtgggttatcttccctggagaagaaggattagattatggtggcgttgcacgggaatgg
ttctttctgttgtcgcatgaagtgctgaatccaatgtattgcctgtttgaatatgcaggg
aaggataactactgcctacagataaaccccgcatcttacatcaatccagaccacttgaaa
tacttccgctttattggcagatttattgccatggcattgtttcatgggaaatttatagac
acaggtttttctctaccattctacaaacgtatcctcaacaagccagtgggactaaaagat
ttagaatccatagatccagagttttacaactcactcatctgggtaaaggaaaacaatatt
gaggaatgcggactggaaatgtatttctcagtggataaagaaattctaggtgaaattaag
agccatgatttgaagcccgatggcagtgatatcttggttactgaggaaaacaaggaagaa
tatatcaagctagtagcagagtggcgactttcccgaggtgttgaagaacagacccaagct
ttctttgaaggcttcaatgagattttaccacagacgtacttgcagtactttgatgccaag
gaactagaggtgcttttgtgtggtatgcaggagattgacttaactgactggcaaaggcat
accatctaccggcattataccagaacaagcaaacaaattgtgtggttttggcagtttgtg
aaggaaatagataatgagaagagaatgagactgctacagtttgttactggaacatgccga
ttgccagttggaggatttgctgatctcatggggagtaatggaccccaaaagttttgtatt
gaaaaagttggtaaagaaaactggttacctagaagccatacttgtttcaatcgcttggac
ttgccaccatacaagagttatgaacaattgaaggagaagcttttgtttgccatagaagag
acagaaggatttgggcaagagtaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (44)   

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