KEGG   Homo sapiens (human): 1656
Entry
1656              CDS       T01001                                 

Symbol
DDX6, HLR2, IDDILF, P54, RCK, Rck/p54
Name
(RefSeq) DEAD-box helicase 6
  KO
K12614  ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Disease
H02463  Syndromic intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    1656 (DDX6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    1656 (DDX6)
   03036 Chromosome and associated proteins [BR:hsa03036]
    1656 (DDX6)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.13  RNA helicase
     1656 (DDX6)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     1656 (DDX6)
  mRNA degradation factors
   5'-3' decay
    Decapping complex
     1656 (DDX6)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Gene silencing
   piRNA pathway
    1656 (DDX6)
SSDB
Motif
Pfam: DEAD Helicase_C CMS1 ResIII
Other DBs
NCBI-GeneID: 1656
NCBI-ProteinID: NP_001244120
OMIM: 600326
HGNC: 2747
Ensembl: ENSG00000110367
Vega: OTTHUMG00000166411
Pharos: P26196(Tbio)
UniProt: P26196 B2R858
Structure
PDB: 

Position
11q23.3
AA seq 483 aa
MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
EKP
NT seq 1452 nt   +upstreamnt  +downstreamnt
atgagcacggccagaacagagaaccctgttataatgggtctgtccagtcaaaatggtcag
ctgagaggccctgtgaaacccactggtggccctggaggagggggcacacagacacagcaa
cagatgaaccagctgaaaaacaccaacacaatcaataatggcactcagcagcaagcacag
agtatgaccaccactattaaacctggtgatgactggaaaaagactttaaaactccctcca
aaggatctaagaatcaaaacttcggatgtgacctccacaaaaggaaatgagtttgaagat
tactgtttgaaacgggagttactgatgggaatttttgaaatgggctgggaaaagccatct
cctattcaggaggagagcattcccattgctttatctggtagggatatcttagctagagca
aaaaatggaacaggcaagagcggtgcctacctcattcccttacttgaacggctagacctg
aagaaggacaatatacaagcaatggtgattgttcccactagagaacttgctctacaggtc
agtcaaatttgcatccaggtcagcaaacacatgggaggggccaaagtgatggcaaccaca
ggaggaaccaatttacgagatgacataatgaggcttgatgatacagtgcacgtggtgatt
gctacccctgggagaatcctggatcttattaagaaaggagtagcaaaggttgatcatgtc
cagatgatagtattggatgaggcagataagttgctgtcacaggattttgtgcagataatg
gaggatattattctcacgctacctaaaaacaggcagattttactatattccgctactttc
cctcttagtgtacagaagttcatgaattcccatttgcagaaaccctatgagattaacctg
atggaggaactaactctgaagggagtaacccagtactacgcatatgtaactgagcgccaa
aaagtacactgcctcaacacacttttctccaggcttcagataaaccagtcgatcattttc
tgtaactcctctcagcgagttgaattgctagccaagaagatttctcaactgggttattct
tgcttctatattcatgctaaaatgaggcaggaacatcgaaatcgtgtatttcatgatttc
cgaaatggcttatgccgcaatcttgtttgcactgatctgtttacccgaggtattgatata
caagctgtgaatgtggtaataaactttgatttcccaaagctggcagagacctatctccat
cgtattggaagatcaggtcgctttggtcatcttggcttagccatcaacttgatcacatat
gatgatcgcttcaacctgaaaagtattgaggagcagctgggaacagaaattaaacctatt
ccgagcaacattgataagagcctgtatgtggcagaataccacagcgagcctgtagaagat
gagaaaccttaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (29)   
   RefSeq(nuc) (7)   
   GenBank (11)   
   EMBL (11)   
Protein domain (4)   
   Pfam (4)   
All databases (82)   

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