KEGG   Homo sapiens (human): 1656
Entry
1656              CDS       T01001                                 
Symbol
DDX6, HLR2, IDDILF, P54, RCK, Rck/p54
Name
(RefSeq) DEAD-box helicase 6
  KO
K12614  ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Disease
H02700  Intellectual developmental disorder with speech delay and dysmorphic facies
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    1656 (DDX6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    1656 (DDX6)
   03036 Chromosome and associated proteins [BR:hsa03036]
    1656 (DDX6)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.7  DEAD-box RNA helicase
     1656 (DDX6)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     1656 (DDX6)
  mRNA degradation factors
   5'-3' decay
    Decapping complex
     1656 (DDX6)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Gene silencing
   piRNA pathway
    1656 (DDX6)
SSDB
Motif
Pfam: DEAD Helicase_C ResIII CMS1 NA-iREase2
Other DBs
NCBI-GeneID: 1656
NCBI-ProteinID: NP_001244120
OMIM: 600326
HGNC: 2747
Ensembl: ENSG00000110367
UniProt: P26196 B2R858
Structure
Position
11:complement(118747763..118791744)
AA seq 483 aa
MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
EKP
NT seq 1452 nt   +upstreamnt  +downstreamnt
atgagcacggccagaacagagaaccctgttataatgggtctgtccagtcaaaatggtcag
ctgagaggccctgtgaaacccactggtggccctggaggagggggcacacagacacagcaa
cagatgaaccagctgaaaaacaccaacacaatcaataatggcactcagcagcaagcacag
agtatgaccaccactattaaacctggtgatgactggaaaaagactttaaaactccctcca
aaggatctaagaatcaaaacttcggatgtgacctccacaaaaggaaatgagtttgaagat
tactgtttgaaacgggagttactgatgggaatttttgaaatgggctgggaaaagccatct
cctattcaggaggagagcattcccattgctttatctggtagggatatcttagctagagca
aaaaatggaacaggcaagagcggtgcctacctcattcccttacttgaacggctagacctg
aagaaggacaatatacaagcaatggtgattgttcccactagagaacttgctctacaggtc
agtcaaatttgcatccaggtcagcaaacacatgggaggggccaaagtgatggcaaccaca
ggaggaaccaatttacgagatgacataatgaggcttgatgatacagtgcacgtggtgatt
gctacccctgggagaatcctggatcttattaagaaaggagtagcaaaggttgatcatgtc
cagatgatagtattggatgaggcagataagttgctgtcacaggattttgtgcagataatg
gaggatattattctcacgctacctaaaaacaggcagattttactatattccgctactttc
cctcttagtgtacagaagttcatgaattcccatttgcagaaaccctatgagattaacctg
atggaggaactaactctgaagggagtaacccagtactacgcatatgtaactgagcgccaa
aaagtacactgcctcaacacacttttctccaggcttcagataaaccagtcgatcattttc
tgtaactcctctcagcgagttgaattgctagccaagaagatttctcaactgggttattct
tgcttctatattcatgctaaaatgaggcaggaacatcgaaatcgtgtatttcatgatttc
cgaaatggcttatgccgcaatcttgtttgcactgatctgtttacccgaggtattgatata
caagctgtgaatgtggtaataaactttgatttcccaaagctggcagagacctatctccat
cgtattggaagatcaggtcgctttggtcatcttggcttagccatcaacttgatcacatat
gatgatcgcttcaacctgaaaagtattgaggagcagctgggaacagaaattaaacctatt
ccgagcaacattgataagagcctgtatgtggcagaataccacagcgagcctgtagaagat
gagaaaccttaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (26)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (17)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (36)   
   RefSeq(nuc) (14)   
   GenBank (11)   
   EMBL (11)   
3D Structure (9)   
   PDB (9)   
Protein domain (5)   
   Pfam (5)   
All databases (95)   

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