KEGG   Homo sapiens (human): 3371
Entry
3371              CDS       T01001                                 
Symbol
TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C
Name
(RefSeq) tenascin C
  KO
K06252  tenascin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa05165  Human papillomavirus infection
hsa05206  MicroRNAs in cancer
Disease
H00604  Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3371 (TNC)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    3371 (TNC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3371 (TNC)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    3371 (TNC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    3371 (TNC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    3371 (TNC)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Extracellular matrix molecules
   3371 (TNC)
SSDB
Motif
Pfam: fn3 EGF_TEN Fibrinogen_C EGF_Teneurin EGF_2 EGF_Tenascin Ig_DSCAM-DSCAML_C Fn3_Dep-1_2nd Pur_ac_phosph_N EGF FN3_Tor_3rd hEGF NDNF DUF4998 fn3_2 Polyketide_cyc2
Other DBs
NCBI-GeneID: 3371
NCBI-ProteinID: NP_002151
OMIM: 187380
HGNC: 5318
Ensembl: ENSG00000041982
UniProt: P24821 Q4LE33 B4E1W8
Structure
Position
9:complement(115019575..115118157)
AA seq 2201 aa
MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPV
GSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVK
ELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGW
KGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFE
GYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECV
CDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQ
CVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVN
GQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRC
VNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQG
RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNN
LGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTH
EGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKF
KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE
ISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIK
DVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLR
RVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTE
YGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS
LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENL
TVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPY
TVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQ
EADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMG
NLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGT
PYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ
VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE
IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP
STDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFL
VTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAE
PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL
REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF
RITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD
GPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPA
TEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLV
YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPF
PKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNW
KAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYK
LKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGD
NNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA
NT seq 6606 nt   +upstreamnt  +downstreamnt
atgggggccatgactcagctgttggcaggtgtctttcttgctttccttgccctcgctacc
gaaggtggggtcctcaagaaagtcatccggcacaagcgacagagtggggtgaacgccacc
ctgccagaagagaaccagccagtggtgtttaaccacgtttacaacatcaagctgccagtg
ggatcccagtgttcggtggatctggagtcagccagtggggagaaagacctggcaccgcct
tcagagcccagcgaaagctttcaggagcacacagtggatggggaaaaccagattgtcttc
acacatcgcatcaacatcccccgccgggcctgtggctgtgccgcagcccctgatgttaag
gagctgctgagcagactggaggagctggagaacctggtgtcttccctgagggagcaatgt
actgcaggagcaggctgctgtctccagcctgccacaggccgcttggacaccaggcccttc
tgtagcggtcggggcaacttcagcactgaaggatgtggctgtgtctgcgaacctggctgg
aaaggccccaactgctctgagcccgaatgtccaggcaactgtcaccttcgaggccggtgc
attgatgggcagtgcatctgtgacgacggcttcacgggcgaggactgcagccagctggct
tgccccagcgactgcaatgaccagggcaagtgcgtaaatggagtctgcatctgtttcgaa
ggctacgccggggctgactgcagccgtgaaatctgcccagtgccctgcagtgaggagcac
ggcacatgtgtagatggcttgtgtgtgtgccacgatggctttgcaggcgatgactgcaac
aagcctctgtgtctcaacaattgctacaaccgtggacgatgcgtggagaatgagtgcgtg
tgtgatgagggtttcacgggcgaagactgcagtgagctcatctgccccaatgactgcttc
gaccggggccgctgcatcaatggcacctgctactgcgaagaaggcttcacaggtgaagac
tgcgggaaacccacctgcccacatgcctgccacacccagggccggtgtgaggaggggcag
tgtgtatgtgatgagggctttgccggtgtggactgcagcgagaagaggtgtcctgctgac
tgtcacaatcgtggccgctgtgtagacgggcggtgtgagtgtgatgatggtttcactgga
gctgactgtggggagctcaagtgtcccaatggctgcagtggccatggccgctgtgtcaat
gggcagtgtgtgtgtgatgagggctatactggggaggactgcagccagctacggtgcccc
aatgactgtcacagtcggggccgctgtgtcgagggcaaatgtgtatgtgagcaaggcttc
aagggctatgactgcagtgacatgagctgccctaatgactgtcaccagcacggccgctgt
gtgaatggcatgtgtgtttgtgatgacggctacacaggggaagactgccgggatcgccaa
tgccccagggactgcagcaacaggggcctctgtgtggacggacagtgcgtctgtgaggac
ggcttcaccggccctgactgtgcagaactctcctgtccaaatgactgccatggccagggt
cgctgtgtgaatgggcagtgcgtgtgccatgaaggatttatgggcaaagactgcaaggag
caaagatgtcccagtgactgtcatggccagggccgctgcgtggacggccagtgcatctgc
cacgagggcttcacaggcctggactgtggccagcactcctgccccagtgactgcaacaac
ttaggacaatgcgtctcgggccgctgcatctgcaacgagggctacagcggagaagactgc
tcagaggtgtctcctcccaaagacctcgttgtgacagaagtgacggaagagacggtcaac
ctggcctgggacaatgagatgcgggtcacagagtaccttgtcgtgtacacgcccacccac
gagggtggtctggaaatgcagttccgtgtgcctggggaccagacgtccaccatcatccag
gagctggagcctggtgtggagtactttatccgtgtatttgccatcctggagaacaagaag
agcattcctgtcagcgccagggtggccacgtacttacctgcacctgaaggcctgaaattc
aagtccatcaaggagacatctgtggaagtggagtgggatcctctagacattgcttttgaa
acctgggagatcatcttccggaatatgaataaagaagatgagggagagatcaccaaaagc
ctgaggaggccagagacctcttaccggcaaactggtctagctcctgggcaagagtatgag
atatctctgcacatagtgaaaaacaatacccggggccctggcctgaagagggtgaccacc
acacgcttggatgcccccagccagatcgaggtgaaagatgtcacagacaccactgccttg
atcacctggttcaagcccctggctgagatcgatggcattgagctgacctacggcatcaaa
gacgtgccaggagaccgtaccaccatcgatctcacagaggacgagaaccagtactccatc
gggaacctgaagcctgacactgagtacgaggtgtccctcatctcccgcagaggtgacatg
tcaagcaacccagccaaagagaccttcacaacaggcctcgatgctcccaggaatcttcga
cgtgtttcccagacagataacagcatcaccctggaatggaggaatggcaaggcagctatt
gacagttacagaattaagtatgcccccatctctggaggggaccacgctgaggttgatgtt
ccaaagagccaacaagccacaaccaaaaccacactcacaggtctgaggccgggaactgaa
tatgggattggagtttctgctgtgaaggaagacaaggagagcaatccagcgaccatcaac
gcagccacagagttggacacgcccaaggaccttcaggtttctgaaactgcagagaccagc
ctgaccctgctctggaagacaccgttggccaaatttgaccgctaccgcctcaattacagt
ctccccacaggccagtgggtgggagtgcagcttccaagaaacaccacttcctatgtcctg
agaggcctggaaccaggacaggagtacaatgtcctcctgacagccgagaaaggcagacac
aagagcaagcccgcacgtgtgaaggcatccactgaacaagcccctgagctggaaaacctc
accgtgactgaggttggctgggatggcctcagactcaactggaccgcagctgaccaggcc
tatgagcactttatcattcaggtgcaggaggccaacaaggtggaggcagctcggaacctc
accgtgcctggcagccttcgggctgtggacataccgggcctcaaggctgctacgccttat
acagtctccatctatggggtgatccagggctatagaacaccagtgctctctgctgaggcc
tccacaggggaaactcccaatttgggagaggtcgtggtggccgaggtgggctgggatgcc
ctcaaactcaactggactgctccagaaggggcctatgagtactttttcattcaggtgcag
gaggctgacacagtagaggcagcccagaacctcaccgtcccaggaggactgaggtccaca
gacctgcctgggctcaaagcagccactcattataccatcaccatccgcggggtcactcag
gacttcagcacaacccctctctctgttgaagtcttgacagaggaggttccagatatggga
aacctcacagtgaccgaggttagctgggatgctctcagactgaactggaccacgccagat
ggaacctatgaccagtttactattcaggtccaggaggctgaccaggtggaagaggctcac
aatctcacggttcctggcagcctgcgttccatggaaatcccaggcctcagggctggcact
ccttacacagtcaccctgcacggcgaggtcaggggccacagcactcgaccccttgctgta
gaggtcgtcacagaggatctcccacagctgggagatttagccgtgtctgaggttggctgg
gatggcctcagactcaactggaccgcagctgacaatgcctatgagcactttgtcattcag
gtgcaggaggtcaacaaagtggaggcagcccagaacctcacgttgcctggcagcctcagg
gctgtggacatcccgggcctcgaggctgccacgccttatagagtctccatctatggggtg
atccggggctatagaacaccagtactctctgctgaggcctccacagccaaagaacctgaa
attggaaacttaaatgtttctgacataactcccgagagcttcaatctctcctggatggct
accgatgggatcttcgagacctttaccattgaaattattgattccaataggttgctggag
actgtggaatataatatctctggtgctgaacgaactgcccatatctcagggctaccccct
agtactgattttattgtctacctctctggacttgctcccagcatccggaccaaaaccatc
agtgccacagccacgacagaggccctgccccttctggaaaacctaaccatttccgacatt
aatccctacgggttcacagtttcctggatggcatcggagaatgcctttgacagctttcta
gtaacggtggtggattctgggaagctgctggacccccaggaattcacactttcaggaacc
cagaggaagctggagcttagaggcctcataactggcattggctatgaggttatggtctct
ggcttcacccaagggcatcaaaccaagcccttgagggctgagattgttacagaagccgaa
ccggaagttgacaaccttctggtttcagatgccaccccagacggtttccgtctgtcctgg
acagctgatgaaggggtcttcgacaattttgttctcaaaatcagagataccaaaaagcag
tctgagccactggaaataaccctacttgcccccgaacgtaccagggacataacaggtctc
agagaggctactgaatacgaaattgaactctatggaataagcaaaggaaggcgatcccag
acagtcagtgctatagcaacaacagccatgggctccccaaaggaagtcattttctcagac
atcactgaaaattcggctactgtcagctggagggcacccacagcccaagtggagagcttc
cggattacctatgtgcccattacaggaggtacaccctccatggtaactgtggacggaacc
aagactcagaccaggctggtgaaactcatacctggcgtggagtaccttgtcagcatcatc
gccatgaagggctttgaggaaagtgaacctgtctcagggtcattcaccacagctctggat
ggcccatctggcctggtgacagccaacatcactgactcagaagccttggccaggtggcag
ccagccattgccactgtggacagttatgtcatctcctacacaggcgagaaagtgccagaa
attacacgcacggtgtccgggaacacagtggagtatgctctgaccgacctcgagcctgcc
acggaatacacactgagaatctttgcagagaaagggccccagaagagctcaaccatcact
gccaagttcacaacagacctcgattctccaagagacttgactgctactgaggttcagtcg
gaaactgccctccttacctggcgacccccccgggcatcagtcaccggttacctgctggtc
tatgaatcagtggatggcacagtcaaggaagtcattgtgggtccagataccacctcctac
agcctggcagacctgagcccatccacccactacacagccaagatccaggcactcaatggg
cccctgaggagcaatatgatccagaccatcttcaccacaattggactcctgtaccccttc
cccaaggactgctcccaagcaatgctgaatggagacacgacctctggcctctacaccatt
tatctgaatggtgataaggctgaggcgctggaagtcttctgtgacatgacctctgatggg
ggtggatggattgtgttcctgagacgcaaaaacggacgcgagaacttctaccaaaactgg
aaggcatatgctgctggatttggggaccgcagagaagaattctggcttgggctggacaac
ctgaacaaaatcacagcccaggggcagtacgagctccgggtggacctgcgggaccatggg
gagacagcctttgctgtctatgacaagttcagcgtgggagatgccaagactcgctacaag
ctgaaggtggaggggtacagtgggacagcaggtgactccatggcctaccacaatggcaga
tccttctccacctttgacaaggacacagattcagccatcaccaactgtgctctgtcctac
aaaggggctttctggtacaggaactgtcaccgtgtcaacctgatggggagatatggggac
aataaccacagtcagggcgttaactggttccactggaagggccacgaacactcaatccag
tttgctgagatgaagctgagaccaagcaacttcagaaatcttgaaggcaggcgcaaacgg
gcataa

  All links  
Disease (2)   
   OMIM (2)   
Gene (197)   
   RefGene (137)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PROTHERM (55)   
Protein sequence (120)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (116)   
DNA sequence (160)   
   RefSeq(nuc) (116)   
   GenBank (22)   
   EMBL (22)   
3D Structure (18)   
   PDB (18)   
Protein domain (16)   
   Pfam (16)   
All databases (513)   

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