KEGG   Homo sapiens (human): 4316Help
Entry
4316              CDS       T01001                                 

Gene name
MMP7, MMP-7, MPSL1, PUMP-1
Definition
(RefSeq) matrix metallopeptidase 7
  KO
K01397  matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
hsa05166  Human T-cell leukemia virus 1 infection
Network
nt06123  TNF signaling (viruses and bacteria)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06223  TNF-NFKB signaling
  Element
N00503  HTLV-1 Tax to TNF-JNK signaling pathway
Drug target
Marimastat: D03795
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    4316 (MMP7)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    4316 (MMP7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    4316 (MMP7)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.23  matrilysin
     4316 (MMP7)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M10
   4316 (MMP7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Peptidase_M10 PG_binding_1 Metallopep Peptidase_M54 Peptidase_M66 Reprolysin_5 Peptidase_M57 Reprolysin_3
Motif
Other DBs
NCBI-GeneID: 4316
NCBI-ProteinID: NP_002414
OMIM: 178990
HGNC: 7174
Ensembl: ENSG00000137673
Vega: OTTHUMG00000048193
Pharos: P09237(Tclin)
UniProt: P09237
Structure
PDB: 

Position
11q22.2
AA seq 267 aa AA seqDB search
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
NT seq 804 nt NT seq  +upstreamnt  +downstreamnt
atgcgactcaccgtgctgtgtgctgtgtgcctgctgcctggcagcctggccctgccgctg
cctcaggaggcgggaggcatgagtgagctacagtgggaacaggctcaggactatctcaag
agattttatctctatgactcagaaacaaaaaatgccaacagtttagaagccaaactcaag
gagatgcaaaaattctttggcctacctataactggaatgttaaactcccgcgtcatagaa
ataatgcagaagcccagatgtggagtgccagatgttgcagaatactcactatttccaaat
agcccaaaatggacttccaaagtggtcacctacaggatcgtatcatatactcgagactta
ccgcatattacagtggatcgattagtgtcaaaggctttaaacatgtggggcaaagagatc
cccctgcatttcaggaaagttgtatggggaactgctgacatcatgattggctttgcgcga
ggagctcatggggactcctacccatttgatgggccaggaaacacgctggctcatgccttt
gcgcctgggacaggtctcggaggagatgctcacttcgatgaggatgaacgctggacggat
ggtagcagtctagggattaacttcctgtatgctgcaactcatgaacttggccattctttg
ggtatgggacattcctctgatcctaatgcagtgatgtatccaacctatggaaatggagat
ccccaaaattttaaactttcccaggatgatattaaaggcattcagaaactatatggaaag
agaagtaattcaagaaagaaatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (1)   
   KEGG NETWORK (1)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (8)   
   Pfam (8)   
All databases (58)   

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