KEGG   Homo sapiens (human): 5908
Entry
5908              CDS       T01001                                 
Symbol
RAP1B, K-REV, RAL1B, THC11
Name
(RefSeq) RAP1B, member of RAS oncogene family
  KO
K07836  Ras-related protein Rap-1B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04024  cAMP signaling pathway
hsa04062  Chemokine signaling pathway
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04611  Platelet activation
hsa04670  Leukocyte transendothelial migration
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04934  Cushing syndrome
hsa04972  Pancreatic secretion
hsa05211  Renal cell carcinoma
hsa05417  Lipid and atherosclerosis
Disease
H00978  Thrombocytopenia (THC)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    5908 (RAP1B)
   04014 Ras signaling pathway
    5908 (RAP1B)
   04015 Rap1 signaling pathway
    5908 (RAP1B)
   04024 cAMP signaling pathway
    5908 (RAP1B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5908 (RAP1B)
   04520 Adherens junction
    5908 (RAP1B)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5908 (RAP1B)
   04670 Leukocyte transendothelial migration
    5908 (RAP1B)
   04062 Chemokine signaling pathway
    5908 (RAP1B)
  09154 Digestive system
   04972 Pancreatic secretion
    5908 (RAP1B)
  09156 Nervous system
   04720 Long-term potentiation
    5908 (RAP1B)
   04722 Neurotrophin signaling pathway
    5908 (RAP1B)
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    5908 (RAP1B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    5908 (RAP1B)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    5908 (RAP1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5908 (RAP1B)
   04031 GTP-binding proteins [BR:hsa04031]
    5908 (RAP1B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5908 (RAP1B)
  Exosomal proteins of other body fluids (saliva and urine)
   5908 (RAP1B)
  Exosomal proteins of colorectal cancer cells
   5908 (RAP1B)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Ras Family
   Rap [OT]
    5908 (RAP1B)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 G-alpha
Other DBs
NCBI-GeneID: 5908
NCBI-ProteinID: NP_001010942
OMIM: 179530
HGNC: 9857
Ensembl: ENSG00000127314
UniProt: P61224
Structure
Position
12:68610899..68671901
AA seq 184 aa
MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
CQLL
NT seq 555 nt   +upstreamnt  +downstreamnt
atgcgtgagtataagctagtcgttcttggctcaggaggcgttggaaagtctgctttgact
gtacaatttgttcaaggaatttttgtagaaaaatacgatcctacgatagaagattcttat
agaaagcaagttgaagtagatgcacaacagtgtatgcttgaaatcttggatactgcagga
acggagcaatttacagcaatgagggatttatacatgaaaaatggacaaggatttgcatta
gtttattccatcacagcacagtccacatttaacgatttacaagacctgagagaacagatt
cttcgagttaaagacactgatgatgttccaatgattcttgttggtaataagtgtgacttg
gaagatgaaagagttgtagggaaggaacaaggtcaaaatctagcaagacaatggaacaac
tgtgcattcttagaatcttctgcaaaatcaaaaataaatgttaatgagatcttttatgac
ctagtgcggcaaattaacagaaaaactccagtgcctgggaaggctcgcaaaaagtcatca
tgtcagctgctttaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (24)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (54)   
   RefSeq(nuc) (6)   
   GenBank (24)   
   EMBL (24)   
3D Structure (23)   
   PDB (23)   
Protein domain (6)   
   Pfam (6)   
All databases (117)   

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