KEGG   Homo sapiens (human): 7222
Entry
7222              CDS       T01001                                 
Symbol
TRPC3, SCA41, TRP3
Name
(RefSeq) transient receptor potential cation channel subfamily C member 3
  KO
K04966  transient receptor potential cation channel subfamily C member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa05017  Spinocerebellar ataxia
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06462  Spinocerebellar ataxia
nt06463  Parkinson disease
nt06466  Pathways of neurodegeneration
nt06528  Calcium signaling
  Element
N00953  mGluR1-TRPC3 signaling pathway
N00955  Mutation-inactivated PRKCG to mGluR1-TRPC3 signaling pathway
N00956  Mutation-activated PRKCG to mGluR1-TRPC3 signaling pathway
N00961  Mutation-activated TRPC3 to mGluR1-TRPC3 signaling pathway
N01741  Ca2+/TRPC3 signaling pathway
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    7222 (TRPC3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    7222 (TRPC3)
   05022 Pathways of neurodegeneration - multiple diseases
    7222 (TRPC3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7222 (TRPC3)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7222 (TRPC3)
SSDB
Motif
Pfam: TRP_2 Ion_trans PKD_channel Ank_2 Ank Ank_4 Ank_5
Other DBs
NCBI-GeneID: 7222
NCBI-ProteinID: NP_001124170
OMIM: 602345
HGNC: 12335
Ensembl: ENSG00000138741
UniProt: Q13507
Structure
Position
4:complement(121874481..121952060)
AA seq 921 aa
MSTKVRKCKEQARVTFPAPEEEEDEGEDEGAEPQRRRRGWRGVNGGLEPRSAPSQREPHG
YCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAA
EYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALL
LAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILA
AHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYL
SLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAIL
NGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIA
IKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDR
FEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQ
LWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARD
KWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMV
FFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIG
YVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPF
SLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNS
ILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATE
ELAILIHKLSEKLNPSMLRCE
NT seq 2766 nt   +upstreamnt  +downstreamnt
atgtccaccaaggtcaggaagtgcaaagaacaagcaagggtgaccttcccggcgccggag
gaggaggaagacgagggcgaggacgagggcgcggagccgcagcgccgccgccggggctgg
aggggcgtcaacggggggctggagccgcgctcggcgccctcgcagcgggagccgcacggc
tactgcccgccgcccttctcccacgggccggacctgtccatggagggaagcccatccctg
agacgcatgacagtgatgcgggagaagggccggcgccaggctgtcaggggcccggccttc
atgttcaatgaccgcggcaccagcctcaccgccgaggaggagcgcttcctcgacgccgcc
gagtacggcaacatcccagtggtgcgcaagatgctggaggagtccaagacgctgaacgtc
aactgcgtggactacatgggccagaacgcgctgcagctggctgtgggcaacgagcacctg
gaggtgaccgagctgctgctcaagaaggagaacctggcgcgcattggcgacgccctgctg
ctcgccatcagcaagggctacgtgcgcatcgtagaggccatcctcaaccaccctggcttc
gcggccagcaagcgtctcactctgagcccctgtgagcaggagctgcaggacgacgacttc
tacgcttacgacgaggacggcacgcgcttctcgccggacatcacccccatcatcctggcg
gcgcactgccagaaatacgaagtggtgcacatgctgctgatgaagggtgccaggatcgag
cggccgcacgactatttctgcaagtgcggggactgcatggagaagcagaggcacgactcc
ttcagccactcacgctcgaggatcaatgcctacaaggggctggccagcccggcttacctc
tcattgtccagcgaggacccggtgcttacggccctagagctcagcaacgagctggccaag
ctggccaacatagagaaggagttcaagaatgactatcggaagctctccatgcaatgcaaa
gactttgtagtgggtgtgctggatctctgccgagactcagaagaggtagaagccattctg
aatggagatctggaatcagcagagcctctggaggtacacaggcacaaagcttcattaagt
cgtgtcaaacttgccattaagtatgaagtcaaaaagtttgtggctcatcccaactgccag
cagcagctcttgacgatctggtatgagaacctctcaggcctaagggagcagaccatagct
atcaagtgtctcgttgtgctggtcgtggccctgggccttccattcctggccattggctac
tggatcgcaccttgcagcaggctggggaaaattctgcgaagcccttttatgaagtttgta
gcacatgcagcttctttcatcatcttcctgggtctgcttgtgttcaatgcctcagacagg
ttcgaaggcatcaccacgctgcccaatatcacagttactgactatcccaaacagatcttc
agggtgaaaaccacccagtttacatggactgaaatgctaattatggtctgggttcttgga
atgatgtggtctgaatgtaaagagctctggctggaaggacctagggaatacattttgcag
ttgtggaatgtgcttgactttgggatgctgtccatcttcattgctgctttcacagccaga
ttcctagctttccttcaggcaacgaaggcacaacagtatgtggacagttacgtccaagag
agtgacctcagtgaagtgacactcccaccagagatacagtatttcacttatgctagagat
aaatggctcccttctgaccctcagattatatctgaaggcctttatgccatagctgttgtg
ctcagcttctctcggattgcgtacatcctccctgcaaatgagagctttggccccctgcag
atctctcttggaaggactgtaaaggacatattcaagttcatggtcctctttattatggtg
ttttttgcctttatgattggcatgttcatactttattcttactaccttggggctaaagtt
aatgctgcttttaccactgtagaagaaagtttcaagactttattttggtcaatatttggg
ttgtctgaagtgacttccgttgtgctcaaatatgatcacaaattcatagaaaatattgga
tacgttctttatggaatatacaatgtaactatggtggtcgttttactcaacatgctaatt
gctatgattaatagctcatatcaagaaattgaggatgacagtgatgtagaatggaagttt
gctcgttcaaaactttggttatcctattttgatgatggaaaaacattacctccacctttc
agtctagttcctagtccaaaatcatttgtttatttcatcatgcgaattgttaactttccc
aaatgcagaaggagaaggcttcagaaggatatagaaatgggaatgggtaactcaaagtcc
aggttaaacctcttcactcagtctaactcaagagtttttgaatcacacagttttaacagc
attctcaatcagccaacacgttatcagcagataatgaaaagacttataaagcggtatgtt
ttgaaagcacaagtagacaaagaaaatgatgaagttaatgaaggtgaattaaaagaaatc
aagcaagatatctccagccttcgttatgaacttttggaagacaagagccaagcaactgag
gaattagccattctaattcataaacttagtgagaaactgaatcccagcatgctgagatgt
gaatga

  All links  
Disease (2)   
   OMIM (2)   
Gene (7)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (31)   
   RefSeq(nuc) (13)   
   GenBank (9)   
   EMBL (9)   
3D Structure (8)   
   PDB (8)   
Protein domain (7)   
   Pfam (7)   
All databases (70)   

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