KEGG   Homo sapiens (human): 7222
Entry
7222              CDS       T01001                                 

Gene name
TRPC3, SCA41, TRP3
Definition
(RefSeq) transient receptor potential cation channel subfamily C member 3
  KO
K04966  transient receptor potential cation channel subfamily C member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa05017  Spinocerebellar ataxia
Network
nt06410  Calcium signaling
nt06462  Spinocerebellar ataxia
nt06463  Parkinson disease
  Element
N00953  mGluR1-TRPC3 signaling pathway
N00955  Mutation-inactivated PRKCG to mGluR1-TRPC3 signaling pathway
N00956  Mutation-activated PRKCG to mGluR1-TRPC3 signaling pathway
N00961  Mutation-activated TRPC3 to mGluR1-TRPC3 signaling pathway
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    7222 (TRPC3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    7222 (TRPC3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7222 (TRPC3)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7222 (TRPC3)
SSDB
Motif
Pfam: Ion_trans TRP_2 PKD_channel Ank_2 Ank_4 PBC MFS_4
Other DBs
NCBI-GeneID: 7222
NCBI-ProteinID: NP_003296
OMIM: 602345
HGNC: 12335
Ensembl: ENSG00000138741
Vega: OTTHUMG00000133069
Pharos: Q13507(Tchem)
UniProt: Q13507
Structure
PDB: 
6CUD 6D7L 5ZBG 6DJS

Position
4q27
AA seq 848 aa
MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLE
ESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEA
ILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLL
MKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALE
LSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVH
RHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGL
PFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVT
DYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIF
IAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEG
LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYS
YYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVV
VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFI
MRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMK
RLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKL
NPSMLRCE
NT seq 2547 nt   +upstreamnt  +downstreamnt
atggagggaagcccatccctgagacgcatgacagtgatgcgggagaagggccggcgccag
gctgtcaggggcccggccttcatgttcaatgaccgcggcaccagcctcaccgccgaggag
gagcgcttcctcgacgccgccgagtacggcaacatcccagtggtgcgcaagatgctggag
gagtccaagacgctgaacgtcaactgcgtggactacatgggccagaacgcgctgcagctg
gctgtgggcaacgagcacctggaggtgaccgagctgctgctcaagaaggagaacctggcg
cgcattggcgacgccctgctgctcgccatcagcaagggctacgtgcgcatcgtagaggcc
atcctcaaccaccctggcttcgcggccagcaagcgtctcactctgagcccctgtgagcag
gagctgcaggacgacgacttctacgcttacgacgaggacggcacgcgcttctcgccggac
atcacccccatcatcctggcggcgcactgccagaaatacgaagtggtgcacatgctgctg
atgaagggtgccaggatcgagcggccgcacgactatttctgcaagtgcggggactgcatg
gagaagcagaggcacgactccttcagccactcacgctcgaggatcaatgcctacaagggg
ctggccagcccggcttacctctcattgtccagcgaggacccggtgcttacggccctagag
ctcagcaacgagctggccaagctggccaacatagagaaggagttcaagaatgactatcgg
aagctctccatgcaatgcaaagactttgtagtgggtgtgctggatctctgccgagactca
gaagaggtagaagccattctgaatggagatctggaatcagcagagcctctggaggtacac
aggcacaaagcttcattaagtcgtgtcaaacttgccattaagtatgaagtcaaaaagttt
gtggctcatcccaactgccagcagcagctcttgacgatctggtatgagaacctctcaggc
ctaagggagcagaccatagctatcaagtgtctcgttgtgctggtcgtggccctgggcctt
ccattcctggccattggctactggatcgcaccttgcagcaggctggggaaaattctgcga
agcccttttatgaagtttgtagcacatgcagcttctttcatcatcttcctgggtctgctt
gtgttcaatgcctcagacaggttcgaaggcatcaccacgctgcccaatatcacagttact
gactatcccaaacagatcttcagggtgaaaaccacccagtttacatggactgaaatgcta
attatggtctgggttcttggaatgatgtggtctgaatgtaaagagctctggctggaagga
cctagggaatacattttgcagttgtggaatgtgcttgactttgggatgctgtccatcttc
attgctgctttcacagccagattcctagctttccttcaggcaacgaaggcacaacagtat
gtggacagttacgtccaagagagtgacctcagtgaagtgacactcccaccagagatacag
tatttcacttatgctagagataaatggctcccttctgaccctcagattatatctgaaggc
ctttatgccatagctgttgtgctcagcttctctcggattgcgtacatcctccctgcaaat
gagagctttggccccctgcagatctctcttggaaggactgtaaaggacatattcaagttc
atggtcctctttattatggtgttttttgcctttatgattggcatgttcatactttattct
tactaccttggggctaaagttaatgctgcttttaccactgtagaagaaagtttcaagact
ttattttggtcaatatttgggttgtctgaagtgacttccgttgtgctcaaatatgatcac
aaattcatagaaaatattggatacgttctttatggaatatacaatgtaactatggtggtc
gttttactcaacatgctaattgctatgattaatagctcatatcaagaaattgaggatgac
agtgatgtagaatggaagtttgctcgttcaaaactttggttatcctattttgatgatgga
aaaacattacctccacctttcagtctagttcctagtccaaaatcatttgtttatttcatc
atgcgaattgttaactttcccaaatgcagaaggagaaggcttcagaaggatatagaaatg
ggaatgggtaactcaaagtccaggttaaacctcttcactcagtctaactcaagagttttt
gaatcacacagttttaacagcattctcaatcagccaacacgttatcagcagataatgaaa
agacttataaagcggtatgttttgaaagcacaagtagacaaagaaaatgatgaagttaat
gaaggtgaattaaaagaaatcaagcaagatatctccagccttcgttatgaacttttggaa
gacaagagccaagcaactgaggaattagccattctaattcataaacttagtgagaaactg
aatcccagcatgctgagatgtgaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (4)   
   KEGG NETWORK (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (24)   
   RefSeq(nuc) (6)   
   GenBank (9)   
   EMBL (9)   
Protein domain (7)   
   Pfam (7)   
All databases (61)   

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