KEGG   Homo sapiens (human): 80055
Entry
80055             CDS       T01001                                 
Symbol
PGAP1, Bst1, ISPD3024, MRT42, NEDDSBA, SPG67
Name
(RefSeq) post-GPI attachment to proteins inositol deacylase 1
  KO
K05294  GPI inositol-deacylase [EC:3.-.-.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
hsa01100  Metabolic pathways
Module
hsa_M00983  GPI-anchor remodeling
Network
nt06018  GPI-anchor biosynthesis
  Element
N01860  GPI-anchor remodeling
Disease
H00768  Autosomal recessive intellectual developmental disorder
H01485  Autosomal recessive mental retardation-42
H01489  Inherited glycosylphosphatidylinositol deficiencies
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
    80055 (PGAP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    80055 (PGAP1)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Others
   Post-GPI attachment to proteins factors (PGAP)
    80055 (PGAP1)
SSDB
Motif
Pfam: PGAP1 PGAP1_TMD PGAP1_3rd PGAP1_2nd Palm_thioest DUF676 Abhydrolase_1 Abhydrolase_6 Hydrolase_4 LIDHydrolase Peptidase_S9 DUF1749 Lipase_3 ChlI
Other DBs
NCBI-GeneID: 80055
NCBI-ProteinID: NP_079265
OMIM: 611655
HGNC: 25712
Ensembl: ENSG00000197121
UniProt: Q75T13
Position
2:complement(196833004..196926707)
AA seq 922 aa
MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLAKR
YPAYELYLYGEGSYAEEHKILPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYH
FDFFSVNFNEELVALYGGSLQKQTKFVHECIKTILKLYKGQEFAPKSVAIIGHSMGGLVA
RALLTLKNFKHDLINLLITQATPHVAPVMPLDRFITDFYTTVNNYWILNARHINLTTLSV
AGGFRDYQVRSGLTFLPKLSHHTSALSVVSSAVPKTWVSTDHLSIVWCKQLQLTTVRAFF
DLIDADTKQITQNSKKKLSVLYHHFIRHPSKHFEENPAIISDLTGTSMWVLVKVSKWTYV
AYNESEKIYFTFPLENHRKIYTHVYCQSTMLDTNSWIFACINSTSMCLQGVDLSWKAELL
PTIKYLTLRLQDYPSLSHLVVYVPSVRGSKFVVDCEFFKKEKRYIQLPVTHLFSFGLSSR
KVVLNTNGLYYNLELLNFGQIYQAFKINVVSKCSAVKEEITSIYRLHIPWSYEDSLTIAQ
APSSTEISLKLHIAQPENNTHVALFKMYTSSDCRYEVTVKTSFSQILGQVVRFHGGALPA
YVVSNILLAYRGQLYSLFSTGCCLEYATMLDKEAKPYKVDPFVIIIKFLLGYKWFKELWD
VLLLPELDAVILTCQSMCFPLISLILFLFGTCTAYWSGLLSSASVRLLSSLWLALKRPSE
LPKDIKMISPDLPFLTIVLIIVSWTTCGALAILLSYLYYVFKVVHLQASLTTFKNSQPVN
PKHSRRSEKKSNHHKDSSIHHLRLSANDAEDSLRMHSTVINLLTWIVLLSMPSLIYWLKN
LRYYFKLNPDPCKPLAFILIPTMAILGNTYTVSIKSSKLLKTTSQFPLPLAVGVIAFGSA
HLYRLPCFVFIPLLLHALCNFM
NT seq 2769 nt   +upstreamnt  +downstreamnt
atgtttcttcactcagttaatctctggaacctggcgttttatgtcttcatggtctttctg
gcaaccctggggctgtgggatgtcttcttcggcttcgaggagaataagtgcagtatgagc
tacatgtttgagtacccggagtatcagaaaatagaacttccaaagaaactggcaaaacgc
tatcccgcatatgagttgtatctttatggagagggatcctatgctgaagaacacaaaatt
ctccctttgacgggtattccagttctctttcttcctggtaatgctggaagttataagcaa
gttcgttctattggctccattgcacttagaaaagcagaggacattgacttcaagtaccac
tttgacttctttagtgtgaacttcaatgaagaactggtggctttgtatggtggaagtctt
cagaagcagaccaagtttgtacatgaatgtattaaaacaattctcaaactctataagggt
caagaatttgctccaaaaagtgtggcaataattggtcattctatgggtggccttgttgca
agagcattgcttacactgaaaaattttaagcatgatctgataaatcttcttattacacaa
gccacacctcatgttgctcctgtgatgccattagatcgtttcattacagatttttatacg
actgtaaacaactattggattctaaatgctcgacacataaatttaaccacactttctgta
gctggaggattccgggattaccaagttcgttcaggattgacttttctaccaaaattaagc
catcataccagtgccttatctgttgtgagttcagcagtgcctaagacctgggtctcaaca
gaccacctctccattgtgtggtgtaaacaattgcagttgactacagttcgagcattcttt
gatcttattgatgctgatactaaacaaataactcaaaattccaagaagaaactgtcagtt
ttgtatcaccactttataagacacccatcaaaacattttgaggaaaatccagctataatt
tctgacttaacagggacatctatgtgggttctagtaaaagtgtccaaatggacctatgta
gcttacaacgaatctgagaagatatattttacatttcctcttgaaaatcatagaaaaatc
tacactcatgtctattgtcagagcactatgctggatacaaatagttggatttttgcttgc
ataaacagcacttctatgtgcctgcaaggggttgatttatcatggaaagctgaactgctg
ccaacaattaagtatctgacattaagacttcaagactatccatctttgtctcatcttgtt
gtttatgtaccatctgttcgtggaagtaagtttgttgtagattgtgaattctttaaaaaa
gagaaaagatacatacagcttcctgtaactcatcttttttcctttggattgtcttcaagg
aaagtggtgttaaatacaaatggcctatactacaatctagagcttctgaactttggacag
atataccaagcttttaaaatcaacgtggtaagcaagtgctcagcagtcaaagaagaaata
accagtatctatagacttcatattccttggtcttatgaagattcactaaccattgcacag
gctccatcttccacagaaatttctctgaaactccatattgctcaaccagaaaacaatacc
catgtggcattatttaaaatgtacacgtcatcagactgtcggtacgaggtgacagttaag
acttccttttcacaaatacttggacaggtagttagatttcatggtggagctcttcctgct
tatgtcgtatctaatatccttcttgcttatagaggacagttatattctcttttctcaaca
ggttgttgcttagaatatgctaccatgttggataaagaagccaaaccatacaaagttgat
ccttttgtaattatcattaagtttctgttggggtataaatggtttaaagaattgtgggat
gtattattgttaccagaattagatgccgtcattttaacttgtcagagtatgtgtttcccc
ctgatatccttgattctctttctgtttggaacgtgtactgcctactggagtggcctactg
tcttctgcatctgtgagacttctttcttcattgtggctagctttgaaaagaccctctgaa
cttcctaaagatatcaagatgatatcaccagacttgccctttttgacaattgtcttgatc
atagttagttggacaacttgtggagcactagccatacttctttcttatctttactatgtg
tttaaggttgttcatctgcaagccagcttaacaacttttaagaatagccagcctgtgaat
cccaaacactctagaagaagtgaaaagaaatccaatcatcataaagactcctcaatacac
catcttcgtttatctgccaacgatgctgaagatagccttcgcatgcacagtactgtgatt
aacttactaacatggattgtattactcagcatgccttctctaatttattggctaaagaat
cttaggtattattttaaacttaatcctgatccatgtaaacctttggcatttatccttatt
ccgactatggcaattcttggaaatacttacactgtttcaataaaatcaagtaaattgttg
aagactacttcacaatttccacttcctctggctgttggtgtgattgcttttgggtcagca
catttatataggcttccatgctttgtcttcattcctcttttactccatgcattatgcaac
tttatgtaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (21)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (37)   
   RefSeq(nuc) (13)   
   GenBank (12)   
   EMBL (12)   
Protein domain (14)   
   Pfam (14)   
All databases (85)   

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