KEGG   VARIANT: 3265v2
Entry
3265v2                      Variant                                
Name
HRAS mutation
Type
Gain of function
Gene
HRAS  HRas proto-oncogene, GTPase [KO:K02833]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutation G12S
ClinVar: 12602
dbSNP: rs104894229
COSM: 480
Variation
mutation G12C
ClinVar: 12613
dbSNP: rs104894229
COSM: 481
Variation
mutation G13R
ClinVar: 35554
dbSNP: rs104894228
COSM: 486
Variation
mutation G13V
ClinVar: 180848
dbSNP: rs104894226
COSM: 489
Variation
mutation Q61R
ClinVar: 160364
dbSNP: rs121913233
COSM: 499
Variation
mutation Q61L
ClinVar: 376033
dbSNP: rs121913233
COSM: 498
Network
nt06210  ERK signaling (cancer)
nt06265  Bladder cancer
nt06526  MAPK signaling
Disease
H00022  Bladder cancer
Reference
PMID:15897885
  Authors
Jebar AH, Hurst CD, Tomlinson DC, Johnston C, Taylor CF, Knowles MA
  Title
FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma.
  Journal
Oncogene 24:5218-25 (2005)
DOI:10.1038/sj.onc.1208705

  All links  
Gene (16)   
   CLINVAR (6)   
   COSM (6)   
   DBSNP (4)   
All databases (16)   

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