KEGG   ORTHOLOGY: K06670
Entry
K06670                      KO                                     
Symbol
SCC1, MCD1, RAD21
Name
cohesin complex subunit SCC1
Pathway
map04110  Cell cycle
map04111  Cell cycle - yeast
Disease
H00631  Cornelia de Lange syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06670  SCC1, MCD1, RAD21; cohesin complex subunit SCC1
   04111 Cell cycle - yeast
    K06670  SCC1, MCD1, RAD21; cohesin complex subunit SCC1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06670  SCC1, MCD1, RAD21; cohesin complex subunit SCC1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   Cohesin complex
    K06670  SCC1, MCD1, RAD21; cohesin complex subunit SCC1
Genes
HSA: 5885(RAD21)
PTR: 464346(RAD21)
PPS: 100988279(RAD21)
GGO: 101129201(RAD21)
PON: 100173158(RAD21)
NLE: 100594167(RAD21)
HMH: 116472638 116813534(RAD21)
MCC: 700633(RAD21)
MCF: 102144357(RAD21)
MTHB: 126961299
MNI: 105475942(RAD21)
CSAB: 103237327(RAD21)
CATY: 105584531(RAD21)
PANU: 100998068(RAD21)
TGE: 112629875(RAD21)
MLEU: 105529091(RAD21)
RRO: 104680782(RAD21)
RBB: 108536116(RAD21)
TFN: 117079544(RAD21)
PTEH: 111551052(RAD21)
CANG: 105511056(RAD21)
CJC: 100404485(RAD21)
SBQ: 101027770(RAD21)
CIMI: 108305881(RAD21)
CSYR: 103264781(RAD21)
MMUR: 105863707(RAD21)
LCAT: 123644987(RAD21)
PCOQ: 105813814(RAD21)
OGA: 100945097 100947086(RAD21)
MMU: 19357(Rad21)
MCAL: 110310451(Rad21)
MPAH: 110334800(Rad21)
RNO: 314949(Rad21)
MCOC: 116081480(Rad21)
ANU: 117718665(Rad21)
MUN: 110558790(Rad21)
CGE: 100750544(Rad21)
MAUA: 101835161(Rad21)
PROB: 127235365(Rad21)
PLEU: 114692254(Rad21)
MORG: 121461175(Rad21)
MFOT: 126491855
AAMP: 119823261(Rad21)
NGI: 103738131(Rad21)
HGL: 101705536(Rad21)
CPOC: 100718361(Rad21)
CCAN: 109688156(Rad21)
DORD: 105997717(Rad21)
DSP: 122102320(Rad21)
PLOP: 125360535(Rad21)
NCAR: 124961737
MMMA: 107142873(Rad21)
OCU: 100350479
OPI: 101534939(RAD21)
TUP: 102491766(RAD21)
GVR: 103581298(RAD21)
CFA: 482021(RAD21)
CLUD: 112662051(RAD21)
VVP: 112915938(RAD21)
VLG: 121498970(RAD21)
NPO: 129502606(RAD21)
AML: 100482392(RAD21)
UMR: 103661576(RAD21)
UAH: 113252796(RAD21)
UAR: 123797770(RAD21)
ELK: 111146574
MPUF: 101690137(RAD21)
MNP: 132014247(RAD21)
MLK: 131826474(RAD21)
NVS: 122904354(RAD21)
ORO: 101370272(RAD21) 101373553
EJU: 114223535(RAD21)
ZCA: 113929312 113932898(RAD21)
MLX: 118015146(RAD21)
NSU: 110579219(RAD21)
LWW: 102748961(RAD21)
FCA: 101095950(RAD21)
PYU: 121042892(RAD21)
PCOO: 112859480(RAD21)
PBG: 122495737(RAD21)
LRUF: 124507768
PTG: 102968329(RAD21)
PPAD: 109273239(RAD21)
PUC: 125924461
AJU: 106975538
HHV: 120228674(RAD21)
BTA: 540966(RAD21)
BOM: 102279360(RAD21)
BIU: 109568477(RAD21)
BBUB: 102395797(RAD21)
BBIS: 105005438(RAD21)
CHX: 102183806(RAD21)
OAS: 101115132(RAD21)
BTAX: 128059161(RAD21)
ODA: 120860714 120878892(RAD21)
CCAD: 122450996(RAD21)
MBEZ: 129560135(RAD21)
SSC: 100738633(RAD21)
CFR: 102507790(RAD21)
CBAI: 105082890(RAD21)
CDK: 105096150(RAD21)
VPC: 102532463(RAD21)
BACU: 103017879(RAD21)
LVE: 103079478(RAD21)
OOR: 101287029(RAD21)
DLE: 111165189(RAD21)
PCAD: 102994095(RAD21)
PSIU: 116742355(RAD21)
NASI: 112397031(RAD21)
ECB: 100065497(RAD21)
EPZ: 103556307(RAD21)
EAI: 106839122(RAD21)
MYB: 102263253(RAD21)
MYD: 102765893(RAD21)
MMYO: 118670753(RAD21)
MLF: 102440251(RAD21)
MNA: 107533188(RAD21)
PKL: 118718224(RAD21)
EFUS: 103287663(RAD21)
HAI: 109382545(RAD21)
DRO: 112315434(RAD21)
SHON: 118988616(RAD21)
AJM: 119050212(RAD21)
PDIC: 114514406(RAD21)
PHAS: 123833290(RAD21)
MMF: 118631498(RAD21)
RFQ: 117033931(RAD21)
PALE: 102882823(RAD21)
PGIG: 120595699(RAD21)
PVP: 105292236(RAD21)
RAY: 107507148(RAD21)
MJV: 108395538(RAD21)
TOD: 119238623(RAD21)
SARA: 101539327(RAD21)
LAV: 100659523(RAD21)
TMU: 101361502
ETF: 101662498(RAD21)
DNM: 101423546(RAD21)
MDO: 100025333(RAD21)
GAS: 123231940(RAD21)
SHR: 100928092(RAD21)
AFZ: 127544387
PCW: 110193569(RAD21)
OAA: 100077349(RAD21)
GGA: 420286(RAD21)
PCOC: 116226281(RAD21L1) 116227690(RAD21)
MGP: 100541813(RAD21) 100545449(RAD21L1)
CJO: 107310505(RAD21) 107323130(RAD21L1)
TPAI: 128090881(RAD21)
LMUT: 125691276(RAD21)
NMEL: 110393829(RAD21) 110408117(RAD21L1)
APLA: 101790719(RAD21)
ACYG: 106042703(RAD21)
CATA: 118252662(RAD21)
AFUL: 116485956(RAD21)
TGU: 100218091(RAD21L1) 100218270(RAD21)
LSR: 110468982(RAD21L1) 110479269(RAD21)
SCAN: 103814202(RAD21) 103818848(RAD21L1)
PMOA: 120505158(RAD21) 120507155(RAD21L1)
OTC: 121331558(RAD21L1) 121337434(RAD21)
PRUF: 121348610(RAD21L1) 121355352(RAD21)
GFR: 102035391(RAD21L1) 102043624(RAD21)
FAB: 101815459(RAD21) 101818011(RAD21L1)
OMA: 130249247(RAD21) 130261369(RAD21L1)
PHI: 102100337(RAD21) 102105498(RAD21L1)
PMAJ: 107200469(RAD21) 107213113(RAD21L1)
CCAE: 111925057(RAD21) 111938127(RAD21L1)
CCW: 104687700(RAD21L1) 104692678(RAD21)
CBRC: 103616162(RAD21L1) 103623525(RAD21)
ETL: 114057982(RAD21) 114062960(RAD21L1)
ZAB: 102065060(RAD21L1) 102068188(RAD21)
ACHL: 103799720(RAD21)
SVG: 106849474(RAD21) 106861596(RAD21L1)
MMEA: 130573560(RAD21L1) 130574526(RAD21)
HRT: 120751523(RAD21) 120760251(RAD21L1)
FPG: 101917829(RAD21)
FCH: 102049423(RAD21)
CLV: 102085398(RAD21)
EGZ: 104123712(RAD21)
NNI: 104018003(RAD21)
PCRI: 104031993(RAD21)
PLET: 104617128(RAD21)
EHS: 104503766(RAD21)
PCAO: 104039925(RAD21)
ACUN: 113476667(RAD21)
TALA: 104360325(RAD21)
PADL: 103914947(RAD21)
AFOR: 103897221(RAD21)
ACHC: 115340375(RAD21)
HALD: 104314674(RAD21)
AGEN: 126049022
GCL: 127013066
CCRI: 104154830(RAD21)
CSTI: 104549724(RAD21)
CMAC: 104483341(RAD21)
MUI: 104539567(RAD21)
BREG: 104643416(RAD21)
FGA: 104075146(RAD21)
GSTE: 104251341(RAD21)
LDI: 104354520(RAD21)
MNB: 103777138(RAD21)
OHA: 104332478(RAD21)
NNT: 104405854(RAD21)
SHAB: 115606592(RAD21)
DPUB: 104297233(RAD21)
PGUU: 104458750(RAD21)
ACAR: 104528505(RAD21)
CPEA: 104386713(RAD21)
AVIT: 104280717(RAD21)
CVF: 104282858(RAD21)
RTD: 128905980(RAD21)
CUCA: 104068508(RAD21)
TEO: 104376812(RAD21)
BRHI: 104488207(RAD21)
AAM: 106496308(RAD21)
AROW: 112977542(RAD21)
NPD: 112953280(RAD21)
TGT: 104573123(RAD21)
DNE: 112989154(RAD21)
SCAM: 104150070(RAD21)
ASN: 102373412(RAD21L1) 102383826(RAD21)
AMJ: 102564074(RAD21L1) 102567594(RAD21)
CPOO: 109313282(RAD21L1) 109321461(RAD21)
GGN: 109292538(RAD21L1) 109305150(RAD21)
PSS: 102445346(RAD21) 102459214(RAD21L1)
CMY: 102935541(RAD21L1) 102942190(RAD21)
CCAY: 125632778(RAD21)
DCC: 119851566(RAD21)
CPIC: 101942798(RAD21) 101944229(RAD21L1)
TST: 117873763(RAD21) 117885886(RAD21L1)
CABI: 116816225(RAD21) 116816806(RAD21L1)
MRV: 120398754(RAD21)
ACS: 100551534(rad21) 100561517(rad21l1)
ASAO: 132775068(RAD21)
PVT: 110070436 110076970(RAD21)
SUND: 121929422(RAD21)
PBI: 103053986(RAD21) 103065680(RAD21L1)
PMUR: 107288217(RAD21) 114923121
CTIG: 120307419(RAD21)
TSR: 106549461(RAD21) 106551105
PGUT: 117659821(RAD21L1) 117668367(RAD21)
APRI: 131194254(RAD21)
PTEX: 113438268(RAD21)
NSS: 113427175(RAD21)
VKO: 123019168(RAD21)
PMUA: 114599807(RAD21L1) 114600302(RAD21)
PRAF: 128417129(RAD21)
ZVI: 118088412(RAD21L1) 118090220(RAD21)
HCG: 128323539(RAD21)
GJA: 107120188(RAD21L1)
STOW: 125439031(RAD21)
EMC: 129333587(RAD21)
XLA: 399129(rad21.L) 503676(rad21.S)
XTR: 100492023(rad21)
NPR: 108786962(RAD21L1) 108790564(RAD21)
RTEM: 120941475(RAD21)
BBUF: 121002754(RAD21)
BGAR: 122938115(RAD21)
MUO: 115479934(RAD21)
GSH: 117355104(RAD21)
DRE: 322275(rad21a) 566831(rad21b) 571082(rad21l1)
PTET: 122323658(rad21b) 122333982(rad21a) 122350259
LROH: 127169294(rad21l1) 127178774(rad21a) 127182125(rad21b)
OMC: 131522567(rad21a) 131526432(rad21b) 131546208(rad21l1)
PPRM: 120473764(rad21l1) 120483050(rad21b) 120491133(rad21a)
RKG: 130078413(rad21a) 130082055(rad21l1) 130084238(rad21b)
MAMB: 125243460(rad21a) 125275094(rad21b) 125280329(rad21l1)
TROS: 130557890(rad21a) 130566875(rad21b) 130568147(rad21l1)
TDW: 130415522(rad21b) 130432837(rad21a)
MANU: 129414904(rad21l1) 129448756(rad21a) 129455299(rad21b)
IPU: 108256659(rad21a) 108257238(rad21b) 108265116(rad21l1)
IFU: 128599624(rad21a) 128607479(rad21l1)
SMEO: 124375610(rad21a) 124376462(rad21b) 124399506(rad21l1)
TFD: 113649845(rad21a) 113656083(rad21l1) 113661368(rad21b)
TVC: 132837522(rad21b) 132840251(rad21a) 132853784(rad21l1)
CMAO: 118798941(rad21a) 118805645(rad21b) 118812942(rad21l1)
CHAR: 105891922 105893623(rad21l1) 105904922(rad21b)
TRU: 101065885(rad21) 101078750
TFS: 130529924(rad21l1) 130532609
TBEN: 117477928 117480401 117484558(rad21l1)
PGEO: 117442817(rad21l1) 117454823 117460941
GACU: 117537477 117542588 117554948(rad21l1)
PLEP: 121946131 121946487(rad21l1) 121957552
SLUC: 116035248 116043587(rad21l1) 116047254(rad21b)
ECRA: 117946949 117947015(rad21l1) 117956286(rad21b)
PPUG: 119197874 119218877 119222175(rad21l1)
AFB: 129097570(rad21b) 129100294(rad21l1) 129109309
CLUM: 117733763(rad21l1) 117738570 117745531
MSAM: 119897917 119905353(rad21l1) 119907451
SCHU: 122863838 122881628 122883188(rad21l1)
ALAT: 119005921 119017440 119022719(rad21l1)
OAU: 116317209(rad21l1) 116318940(rad21b) 116322610
OLA: 100049255(rad21) 101173147
OML: 112143771 112159547(rad21l1)
PPRL: 129354185(rad21b) 129367649 129370132(rad21l1)
CTUL: 119777094 119778041 119799355(rad21l1)
GMU: 124866359 124879224(rad21b) 124883868(rad21l1)
NWH: 119410181 119416852(rad21l1) 119425881(rad21b)
MCEP: 125016476 125018768(rad21l1) 125020375
SSEN: 122775017 122776922(rad21l1) 122786166
HHIP: 117764084(rad21l1) 117770083 117776502
HCQ: 109512921 109529660(rad21)
SSCV: 125975195
BSPL: 114843462 114858504(rad21l1) 114865960(rad21b)
SJO: 128357646(rad21l1) 128366361 128374177(rad21b)
AANG: 118211911(rad21l1) 118234075(rad21b) 118236671
LOC: 102684167 102689538(rad21)
PSEX: 120516276
LCM: 102345596(RAD21L1) 102352395(RAD21)
CMK: 103171617 103181205(rad21b)
RTP: 109916220 109924678(rad21)
CPLA: 122549342(rad21b) 122559883
HOC: 132811612(rad21b)
LERI: 129696561(rad21b) 129707341
PMRN: 116945108 116951600(RAD21)
BFO: 118404259
CIN: 100180856
SCLV: 120336855
SPU: 575281
LPIC: 129262725
APLC: 110986201
AJC: 117124675
SKO: 100376067
DME: Dmel_CG17436(vtd)
DSE: 116800942
DSI: Dsimw501_GD22816(Dsim_GD22816)
DSR: 110180481
DPO: 26532716
DPE: 6594402
DMN: 108156468
DWI: 6647688
DGR: 6566687
DAZ: 108611817
DNV: 115563795
DHE: 111592630
DVI: 6628853
CCAT: 105664446
BOD: 106623072
BDR: 105226179
RZE: 108378554
SCAC: 106088648
LCQ: 111686654
LSQ: 119600062
GFS: 119634615
ECOE: 129943362
CLON: 129605735
HIS: 119650670
AGA: 1274701
ACOZ: 120953579
AARA: 120898227
AMER: 121603427
AFUN: 125764119
AMOU: 128298924
AALI: 118458094
AAG: 110681196
CPII: 120415681
CNS: 116338436
BCOO: 119075316
AME: 411619
ACER: 107994642
ALAB: 122712467
ADR: 102671602
AFLR: 100866094
BIM: 100743935
BBIF: 117214767
BVK: 117232362
BVAN: 117164776
BTER: 100645942
BAFF: 126914662
BPYO: 122567090
BPAS: 132909611
FVI: 122528560
CCAL: 108623982
OBB: 114877801
MGEN: 117218866
NMEA: 116432776
CGIG: 122404247
SOC: 105195931
MPHA: 105828317
AEC: 105150037
ACEP: 105620654
PBAR: 105426935
VEM: 105558806
HST: 105182530
DQU: 106748039
CFO: 105253161
FEX: 115241725
LHU: 105670317
PGC: 109862180
OBO: 105277268
PCF: 106793731
PFUC: 122516464
VPS: 122628294
VCRB: 124424942
NVI: 100118241
CSOL: 105363786
TPRE: 106654606
LHT: 122498656
LBD: 127287168
MDL: 103572402
CGLO: 123275089
FAS: 105268655
DAM: 107036020
AGIF: 122853154
CINS: 118070560
VCAN: 122417039
CCIN: 107265352
DSM: 124407949
NPT: 124211644
NFB: 124187717
NLO: 107226357
NVG: 124298107
TCA: 657552(rad21)
DPA: 109546237
SOY: 115888812
AGRG: 126733742
ATD: 109596503
CSET: 123319139
AGB: 108906917
LDC: 111506578
NVL: 108568858
APLN: 108734739
PPYR: 116166719
OTU: 111429408
BMOR: 101738992
BMAN: 114239914
MSEX: 115447077
BANY: 112049645
MJU: 123869018
NIQ: 126772666
VCD: 124535043
MCIX: 123658010
PMAC: 106713142
PXU: 106113438
PRAP: 110998979
PBX: 123708134
PNAP: 125049379
ZCE: 119836774
CCRC: 123694869
LSIN: 126966694
HAW: 110377161
HZE: 124634334
TNL: 113505782
SLIU: 111356105
OFU: 114353918
PXY: 105382496
PGW: 126370038
CFEL: 113378217
CCRN: 123306115
API: 100167520
DNX: 107173614
AGS: 114120499
RMD: 113557006
ACOO: 126839207
DVT: 126902404
BTAB: 109032186
DCI: 103513421
CLEC: 106674443
HHAL: 106691566
NLU: 111054350
HVI: 124374778
FOC: 113202573
TPAL: 117647248
ZNE: 110832502
FCD: 110845458
DPX: DAPPUDRAFT_114887(Rad21)
DMK: 116928566
DPZ: 124344071
PVM: 113801972
PJA: 122256356
PCHN: 125037346
PMOO: 119594745
HAME: 121872898
PCLA: 123768125
CQD: 128700652
PTRU: 123498068
HAZT: 108666023
LSM: 121123942
TCF: 131891259
PPOI: 119103034
DSV: 119450408
RSAN: 119383110
RMP: 119170560
VDE: 111246007
VJA: 111265911
CSCU: 111631648
PTEP: 107438426
CEL: CELE_F10G7.4(scc-1) CELE_K08A8.3(coh-1)
CBR: CBG_04295(Cbr-scc-1) CBG_16697(Cbr-coh-1)
BMY: BM_BM3284(Bm3284)
TSP: Tsp_10009
PCAN: 112562944
BGT: 106075003
GAE: 121376911
HRF: 124110969
HRJ: 124288464
CVN: 111133682
CANU: 128171178
OED: 125683331
MYI: 110443561
MCAF: 127723127
MMER: 123540197
RPHI: 132760223
OBI: 106877019
OSN: 115211098
SHX: MS3_00002561(RAD21)
EGL: EGR_04599
NVE: 5509993
EPA: 110239113
ATEN: 116301533
ADF: 107336858
AMIL: 114961252
PDAM: 113666606
SPIS: 111335164
HSY: 130647374
AQU: 100633475
ATH: AT3G59550(SYN3) AT5G05490(SYN1) AT5G16270(SYN4) AT5G40840(SYN2)
LJA: Lj1g3v2842390.1(Lj1g3v2842390.1) Lj1g3v2842390.2(Lj1g3v2842390.2) Lj1g3v3833930.1(Lj1g3v3833930.1) Lj1g3v3833930.2(Lj1g3v3833930.2) Lj3g3v0883700.1(Lj3g3v0883700.1)
DOSA: Os01t0897800-01(Os01g0897800) Os04t0488100-01(Os04g0488100) Os08t0266700-01(Os08g0266700)
SMO: SELMODRAFT_415062(SYN1-2) SELMODRAFT_451421(SYN1-1)
APRO: F751_1340
MIS: MICPUN_55713(RAD)
SCE: YDL003W(MCD1)
SEUB: DI49_1051
ERC: Ecym_5290
KMX: KLMA_30188(MCD1)
NCS: NCAS_0I00820(NCAS0I00820)
NDI: NDAI_0A08210(NDAI0A08210)
TPF: TPHA_0A04510(TPHA0A04510)
TBL: TBLA_0F00340(TBLA0F00340)
TDL: TDEL_0D04100(TDEL0D04100)
KAF: KAFR_0F02530(KAFR0F02530)
KNG: KNAG_0K01450(KNAG0K01450)
LEL: PVL30_002355(MCD1)
CAL: CAALFM_CR10540CA(MCD1)
NCR: NCU03291
NTE: NEUTE1DRAFT72223(NEUTE1DRAFT_72223)
SMP: SMAC_04566(putative_mcd1/scc1/rad21)
MGR: MGG_09891
PGRI: PgNI_06299
SSCK: SPSK_08789
MAW: MAC_02982
MAJ: MAA_04201
CMT: CCM_06231
PTKZ: JDV02_001448(MCD1)
BFU: BCIN_07g02490(Bcmcd1)
MBE: MBM_01320
ANI: AN7465.2
ALUC: AKAW2_11213S(MCD1)
ACHE: ACHE_80284S(MCD1)
APUU: APUU_80583S(MCD1)
ABE: ARB_05060(MCD1)
TVE: TRV_01439(MCD1)
PTE: PTT_02779
SPO: SPCC338.17c(rad21)
SOM: SOMG_04492(rad21)
CNE: CND01530
CNB: CNBD4790
ABP: AGABI1DRAFT112610(AGABI1DRAFT_112610)
ABV: AGABI2DRAFT192574(AGABI2DRAFT_192574)
SCM: SCHCO_02584029(SCHCODRAFT_02584029)
MGL: MGL_3889
MRT: MRET_2738
PTRC: PtA15_5A10
DFA: DFA_03417
EHI: EHI_093880(3.t00031)
CPV: cgd7_290
FCY: FRACYDRAFT_263327(RAD21)
SPAR: SPRG_13922
GTT: GUITHDRAFT_104124(Rad21/Scc1)
 » show all
Reference
  Authors
Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL
  Title
Caspase proteolysis of the cohesin component RAD21 promotes apoptosis.
  Journal
J Biol Chem 277:16775-81 (2002)
DOI:10.1074/jbc.M201322200
  Sequence
[hsa:5885]

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