KEGG   Mus caroli (Ryukyu mouse): 110294038
Entry
110294038         CDS       T05910                                 
Symbol
Flt1
Name
(RefSeq) vascular endothelial growth factor receptor 1
  KO
K05096  FMS-like tyrosine kinase 1 [EC:2.7.10.1]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal04010  MAPK signaling pathway
mcal04014  Ras signaling pathway
mcal04015  Rap1 signaling pathway
mcal04020  Calcium signaling pathway
mcal04066  HIF-1 signaling pathway
mcal04151  PI3K-Akt signaling pathway
mcal04510  Focal adhesion
mcal05202  Transcriptional misregulation in cancer
mcal05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110294038 (Flt1)
   04014 Ras signaling pathway
    110294038 (Flt1)
   04015 Rap1 signaling pathway
    110294038 (Flt1)
   04066 HIF-1 signaling pathway
    110294038 (Flt1)
   04020 Calcium signaling pathway
    110294038 (Flt1)
   04151 PI3K-Akt signaling pathway
    110294038 (Flt1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110294038 (Flt1)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    110294038 (Flt1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    110294038 (Flt1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcal01001]
    110294038 (Flt1)
Enzymes [BR:mcal01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     110294038 (Flt1)
Protein kinases [BR:mcal01001]
 Receptor tyrosine kinases (RTK)
  VEGFR family [OT]
   110294038 (Flt1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ig_3 I-set Pkinase ig Ig_2 VEGFR-1-like_Ig-like V-set VEGFR-2_TMD C1-set Ig_4 Ig_6 Ig_5 Izumo-Ig Herpes_gE_N Haspin_kinase ABC1
Other DBs
NCBI-GeneID: 110294038
NCBI-ProteinID: XP_021017663
Ensembl: MGP_CAROLIEiJ_G0028041
UniProt: A0A6P5PR22
Position
5:complement(141139974..141303508)
AA seq 1333 aa
MVSCWDTAVLPYALLGCLLLTGYGSGSKLKVPELSLKGTQHVMQAGQTLFLKCRGEAAHS
WSLPTTVSQEDKRLSITPPSACGRNNRQFCSTLTLDMAQANHTGLYTCRYLPKSTSKKKK
VESSIYIFVSDAGSPFIEMHTDIPKLVHMTEGRQLIIPCRVTSPNVTVTLKKFPFDTLTP
DGQRITWDSMRGFIIANATYKEIGLLNCEATVNGHLYQTNYLTHRQTNTILDVQIRPPSP
VRLLHGQTLVLNCTATTELNTRVQMSWNYPGKATKRASIRQRIDRSHSHNNVFHSVLKIN
NVESRDKGLYTCRVKSGSSFQSFNTSVHVYEKGFISVKHRKQPVQETTAGRRSYRLSMKV
KAFPSPEIVWLKDGSPATLKSARYLVHGYSLIIKDVTTEDAGDYTILLGIKQSRLFKNLT
ATLIVNVKPQIYEKSVSSLPSPPLYPLGSRQVLTCTVYGIPRPTITWLWHPCHHNHSKER
YDFCIENEESFILDPSSNLGNRIESITQRMTVIEGTNKTVSTLVVADSRTPGIYSCRAFN
KIGTVERNIKFYVTDVPNGFHVSVEKMPAEGEDLKLSCVVNKFLYRDITWILLRTVNNRT
MHHSISKQKMATTQDYSITLNLVIKNVSLEDSGTYACRARNIYTGEDILRKTEVLVRDSE
APHLLQNLSDHEVSISGSTTLDCQARGVPAPQITWFKNNHKIQQEPGIILGPGNSTLFIE
RVTEEDEGVYRCRATNQKGAVESAAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLF
IRKLKRSSSEVKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFG
KVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACT
KQGGPLMVIVEYCKYGNLSNYLKSKRDLFCLNKDAVLHMELKKENLEPGLEQGQKPRLDS
VSSSSITSSSFPEDRSVSDVEGDEDYSEISKQPLTMEDLISYSFQVARGMEFLSSRKCIH
RDLAARNILLSENNVVKICDFGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVYSTKS
DVWSYGVLLWEIFSLGGSPYPGIQMDEDFCSRLKEGMRMRTPEYATPEIYRIMLDCWHKD
PKERPRFAELVEKLGDLLQANVQQDGKDYIPLNAILTRNSGFTYSTPTFSEDLFKDGFAD
PQFHSGSSDDVRYVNAFKFMSLERIKTFEELSPNSTSMFEDYQLDTSTLLGSPLLKRFTW
TETKPKASMKIDLRIASKSKEAGLSDLPRPSFCFSSCGHIRPVQDDDSELGKESCCSPPP
DYNSVVLYSSPPA
NT seq 4002 nt   +upstreamnt  +downstreamnt
atggtcagctgctgggacaccgcggtcttgccttacgcgctgctcgggtgtctgcttctt
acaggatatggctcagggtcgaagttaaaagtacctgaactgagtttaaaaggcacccag
catgtcatgcaagcaggccagactctctttctcaagtgcagaggggaggcagcccactca
tggtctctgcccacaaccgtgagccaggaggacaaaaggctgagcatcactcccccatcg
gcctgtgggaggaataacaggcaattctgcagcaccttgaccttggacatggcgcaggcc
aaccacacgggcctctacacctgtagatacctccctaaatctacttcgaagaaaaagaaa
gtggaatcttcaatctacatatttgttagtgatgcagggagtcctttcatagagatgcac
actgacatacccaaacttgtgcacatgacggaaggaagacagctcatcatcccctgccgg
gtgacgtcacccaacgtcacagtcaccctaaaaaagtttccatttgatactcttaccccc
gacgggcaaagaataacgtgggacagtatgagaggctttataatagcaaatgcaacgtac
aaagagataggactgctgaactgcgaagccaccgtcaacgggcacctgtaccagacaaac
tatctgacccatcggcagaccaatacaatcctggatgtccaaatacgcccgccgagccca
gtgagactgctccacgggcagactcttgtcctcaactgcaccgccaccacggagctcaat
acgagggtgcagatgagctggaattaccctggtaaagcaactaagagagcatctataagg
cagcggatcgaccggagccattcccacaacaatgtgttccacagtgttcttaagatcaac
aatgtggagagccgagacaaggggctctacacctgtcgcgtgaagagtgggtcgtcgttc
cagtctttcaacacctccgtgcatgtgtatgaaaaaggattcatcagtgtgaagcatcgg
aagcagccggtgcaggaaaccacggcaggaagacggtcctatcggctgtccatgaaagtg
aaggctttcccctccccagaaatcgtatggttaaaagatggctcgcctgcaacgttgaag
tctgctcgctatttggtacatggctactcgttaattatcaaagatgtgacaaccgaggat
gcaggggactacacgatcttgctgggcataaagcagtcaaggctatttaaaaacctcact
gccactctcattgtaaacgtgaaacctcagatctacgaaaagtccgtgtcctcgcttcca
agcccacctctctacccgctgggcagcagacaagtcctcacttgcaccgtgtatggcatc
cctcggccaacaatcacgtggctctggcacccctgtcaccacaatcactccaaagaaagg
tatgacttctgcattgagaatgaagaatcctttatcctggatcccagcagcaacttagga
aacagaattgagagcatcactcagcgcatgacggttatagaaggaacaaataagacggtt
agcacattggtggtggctgactctcggacccctggaatctacagctgccgggccttcaat
aaaatagggactgtggaaagaaacataaaattttacgtcacagatgtgccgaatggcttt
cacgtttccgtggaaaagatgccagccgaaggagaggacctgaaactgtcctgtgtggtc
aataaattcctgtacagagacattacctggattctgctacggacagttaacaacagaacc
atgcatcatagtatcagcaagcaaaaaatggccaccactcaagattactccatcactctg
aaccttgtcatcaagaacgtgtctctagaggactcgggcacctacgcgtgcagagccagg
aacatatacacaggggaagacatccttcggaagacagaagttctcgttagagattcggaa
gcgccacacctgcttcaaaacctcagtgaccacgaggtctccatcagtggctctacgacc
ttagactgtcaagctagaggtgtccccgcgcctcagatcacttggttcaaaaacaaccac
aaaatacaacaagaacccggaattattttaggaccgggaaacagcacgctgtttattgaa
agagtcacagaggaggatgagggtgtctataggtgccgagccaccaaccagaagggggcc
gtggaaagtgcagcctacctcaccgtgcaaggaacctcagacaagtcaaacctggagctg
atcacgctcacgtgcacatgcgtggctgcgaccctcttttggctccttctaactctcttc
atcagaaaactgaagcggtcttcttccgaagtaaagacggactacctgtcaatcataatg
gatccagatgaagttcccctggatgagcagtgtgaaaggctgccctatgatgccagcaag
tgggagtttgcacgggagagactgaaactaggcaaatcgctcggaagaggggcttttggg
aaagtcgttcaagcctctgcatttggcattaagaaatcacccacctgccggactgtggct
gtgaagatgttgaaagagggggccacagccagtgagtacaaagctctgatgactgaactc
aagatcttgacccacatcggccatcatctgaatgtggttaacctcctgggagcctgcacg
aagcaaggagggcctctgatggtgatcgtggaatactgcaaatacggaaacctgtccaac
tacctcaagagcaaacgtgacttattctgtctcaacaaggacgcagtcttgcatatggag
ctcaagaaagagaacctggaaccaggcctggagcagggccagaagccccgcctagacagt
gtcagcagctcaagcatcaccagctccagcttccctgaagaccgaagcgtgagcgatgtg
gaaggagacgaggattacagtgagatctccaagcagcccctcaccatggaagacctgatt
tcctacagtttccaagtggccagaggcatggagtttctgtcctccagaaagtgcattcat
cgggacctggcagcgagaaacatccttttatctgagaacaatgtggtgaagatttgcgac
tttggcctggcccgggatatttataagaaccctgattatgtgaggagaggagatactcga
cttcccctaaaatggatggctcctgaatccatctttgacaaggtctacagcaccaagagt
gatgtgtggtcctatggcgtgttgctgtgggagatcttctccttagggggttctccatac
ccaggaatacaaatggatgaagacttctgcagccgcctgaaggaaggcatgcggatgaga
accccagagtatgccacacctgaaatctaccgaatcatgttggattgctggcacaaagac
cccaaagagaggccccggtttgctgaactcgtggagaaacttggtgacctgcttcaagcc
aacgtccaacaggatgggaaagactacatccccctcaatgccatactgacgagaaacagc
ggcttcacatactcaacccccaccttctctgaggaccttttcaaggatggctttgcagat
ccacagtttcattccggaagctctgatgatgtgagatacgtaaacgctttcaaattcatg
agcctggaaagaatcaaaacctttgaggagctttcgccgaactccacctccatgtttgag
gactatcagctggacactagcactctgctgggctcccccttgctgaagcggttcacctgg
actgagaccaagcccaaggcctccatgaagatagacttgagaatagcaagtaaaagcaag
gaggcgggactttccgatctgccaaggcccagcttctgcttctccagctgtggccacatc
aggccggtgcaggatgacgactctgagctggggaaggagtcctgctgttctccaccccca
gactacaactccgtggtgttgtactcctccccgcccgcctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (17)   
   Pfam (17)   
All databases (38)   

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