KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100591579
Entry
100591579         CDS       T03265                                 

Gene name
MECOM
Definition
(RefSeq) histone-lysine N-methyltransferase MECOM isoform X1
  KO
K04462  ecotropic virus integration site 1 protein
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle05200  Pathways in cancer
nle05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100591579 (MECOM)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100591579 (MECOM)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    100591579 (MECOM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:nle03000]
    100591579 (MECOM)
Transcription factors [BR:nle03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 developmental/cell cycle regulators, Krueppel-like
    100591579 (MECOM)
SSDB
Motif
Pfam: zf-C2H2 zf-H2C2_2 zf-C2H2_4 zf-C2H2_6 zf-C2H2_jaz zf-H2C2_5 zf-BED zf-C2H2_8 Zn-ribbon_8 zf-C2H2_11 zf-met PyrI_C
Other DBs
NCBI-GeneID: 100591579
NCBI-ProteinID: XP_030678649
Ensembl: ENSNLEG00000004964
Position
11
AA seq 1230 aa
MRSKGRARKLATNNECVYGTYPEIPLEDMPDADGVASTPSLNIQEPCSPATSSEAFTPKE
GSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQRSNLKDP
SYGWEILDEFYNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIA
PGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFS
MVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAF
NWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATS
SGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSL
NKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLT
FPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQD
ILKALSKHPSVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSD
LESDIESDKEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVND
SIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPL
KMEPQSPGEVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSR
SRASGTKLTEPRKNHVFGEKKGSNIESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPL
EALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSMFNFRAPPNAL
PENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVR
NIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKED
AYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLLDE
EDEDNDITGKTGKEPVTSNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSALDH
IRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDKESL
HSTSHSSSNVWHSMARAAAESSAIQSISHV
NT seq 3693 nt   +upstreamnt  +downstreamnt
atgagatccaaaggcagggcaaggaaactggccacaaacaatgagtgtgtatatggcacc
taccctgaaatacctttggaagacatgccagatgcagatggagtagccagcactccctcc
ctcaatattcaagagccatgctctcctgccacatccagtgaagcattcactccaaaggag
ggttctccttacaaagcccccatctacatccctgatgatatccccattcctgctgagttt
gaacttcgagagtcaaatatgcctggagcaggactaggaatatggaccaaaaggaagatc
gaagtaggtgaaaagtttgggccttatgtgggagagcagaggtcaaacctgaaagacccc
agttacggatgggagatcttagatgaattttacaatgtgaagttctgcatagatgccagt
caaccagatgttggaagctggctcaagtacattcgattcgctggctgttatgatcagcac
aacctcgttgcatgccagataaatgatcagatattctatagagtagttgcagacattgcg
ccgggagaggagcttctgctgttcatgaagagcgaagactatccccatgaaactatggcg
ccggatatccacgaagaacggcaatatcgctgtgaagactgtgaccagctctttgaatct
aaggctgaactagcagatcaccaaaagtttccatgcagtactcctcactcagcattttca
atggtcgaagaggactttcagcaaaaactcgaaagcgagaatgatctccaagagatacac
acgatccaggagtgtaaggaatgtgaccaagtttttcctgatttgcaaagcctggagaaa
cacatgctgtcacatactgaagagagggaatacaagtgtgatcagtgtcccaaggcattt
aactggaagtccaatttaattcgccaccagatgtcacatgacagtggaaagcactatgaa
tgtgaaaactgtgccaaggttttcacggaccctagcaaccttcagcggcacattcgctct
cagcatgtcggtgcccgggcccatgcatgcccggagtgtggcaaaacgtttgccacttcg
tcgggcctcaaacaacacaagcacatccacagcagtgtgaagccctttatctgtgaggtc
tgccataaatcctatactcagttttcaaacctttgccgtcataagcgcatgcatgctgat
tgcagaacccaaatcaagtgcaaagactgtggacaaatgttcagcactacgtcttcctta
aataaacacaggaggttttgtgagggcaagaaccattttgcggcaggtggattttttggc
caaggcatttcacttcctggaaccccagctatggataaaacgtccatggttaatatgagt
catgccaacccgggccttgctgactattttggcgccaataggcatcctgctggtcttacc
tttccaacagctcctggattttcttttagcttccctggtctgtttccttccggcttgtac
cacaggcctcctttgatacctgctagttctcctgttaaaggactatcaagtactgaacag
acaaacaaaagtcaaagtcccctcatgacacatcctcagatactgccagctacacaggat
attttgaaggcactatctaaacacccatctgtaggggacaataagccagtggagctccag
cccgagaggtcctctgaagagaggccccttgagaaaatcagtgaccagtcagagagtagt
gaccttgatgatgtcagtacaccaagtggcagtgacctggaaacaacctcgggctctgat
ctggaaagtgacattgaaagtgataaagagaaatttaaagaaaatggtaaaatgttcaaa
gacaaagtaagccctcttcagaatctggcttcaataaataataagaaagaatacagcaat
cattccattttctcaccatctttagaggagcagactgcggtgtcaggagctgtgaatgat
tctataaaggctattgcttctattgctgaaaaatactttggttcaacaggactggtgggg
ctgcaagacaaaaaagttggagctttaccttacccttccatgtttcccctcccatttttt
ccagcattctctcaatcaatgtacccatttcctgatagagacttgagatcgttacctttg
aaaatggaaccccaatcaccaggtgaagtaaagaaactgcagaagggcagctctgagtcc
ccctttgatctcaccactaagcgaaaggatgagaagcccttgactccagtcccctccaag
cctccagtgacgcctgccacaagccaagaccagcccctggatctaagtatgggcagtagg
agtagagccagtgggacaaagctgactgagcctcgaaaaaaccatgtgtttggggaaaaa
aaaggaagcaacattgaatcaagacctgcttcagatggttccttgcagcatgcaagaccc
actcctttctttatggaccctatttacagagtagagaaaagaaaactaactgacccactt
gaagctttaaaagagaaatacttgaggccttctccaggattcttgtttcacccacaaatg
tcagctattgaaaacatggcagaaaagctagagagcttcagtgccctgaaacctgaggcc
agtgagctcttacagtcagtgccctctatgttcaacttcagggcacctcccaatgccctg
ccagagaaccttctgcggaagggaaaggagcgctatacctgcagatactgtggcaagatt
tttccaaggtctgcaaacctaacacggcacttgagaacccacacaggagagcagccttac
agatgcaaatactgtgacagatcatttagcatatcttctaacttgcaaaggcatgttcgc
aacatccacaataaagagaagccatttaagtgtcacttatgtgataggtgttttggtcaa
caaaccaatttagacagacacctaaagaaacatgagaatgggaacatgtccggtacagca
acatcgtcgcctcattctgaactggaaagtacaggtgcgattctggatgacaaggaagat
gcttacttcacagaaattcgaaatttcattgggaacagcaaccacggcagccagtctccc
aggaatgtggaggagagaatgaatggcagtcattttaaagatgaaaaggctttggtgacc
agtcaaaattcagacttgctggatgatgaagaagttgaagatgaggtgttgttagatgag
gaggatgaagacaacgatattactggaaaaacaggaaaggaaccagtgacaagtaattta
catgaaggaaaccctgaggatgactatgaagaaaccagtgccctggagatgagttgcaag
acatccccagtgcggtataaagaggaagaatataaaagtggactttctgctttagatcat
ataaggcacttcacagatagcctcaaaatgaggaaaatggaagataatcaatattctgaa
gctgagctgtcttcttttagtacttcccatgtgccagaggaacttaagcagccgttacac
agaaagtccaaatcgcaggcatatgctatgatgctgtcattgtctgacaaggagtccctc
cattctacatcccacagttcttccaacgtgtggcacagtatggccagggctgcagcggaa
tccagtgctatccagtccataagccacgtatga

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