KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100591579
Entry
100591579         CDS       T03265                                 
Symbol
MECOM
Name
(RefSeq) histone-lysine N-methyltransferase MECOM isoform X1
  KO
K04462  [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00310  Lysine degradation
nle01100  Metabolic pathways
nle04010  MAPK signaling pathway
nle05200  Pathways in cancer
nle05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:nle00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    100591579 (MECOM)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100591579 (MECOM)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100591579 (MECOM)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    100591579 (MECOM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:nle03000]
    100591579 (MECOM)
   03036 Chromosome and associated proteins [BR:nle03036]
    100591579 (MECOM)
Enzymes [BR:nle01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.367  [histone H3]-lysine9 N-methyltransferase
     100591579 (MECOM)
Transcription factors [BR:nle03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 PRDM
    100591579 (MECOM)
Chromosome and associated proteins [BR:nle03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     100591579 (MECOM)
SSDB
Motif
Pfam: zf-C2H2 zf-H2C2_2 zf-C2H2_4 PRDM2_PR zf-C2H2_6 zf-C2H2_jaz SET C2CH-3rd_BIRD-IDD zf-H2C2_5 Zap1_zf1 zf-met zf-BED zf-C2H2_8 Zn_ribbon_8 HVO_0758 DUF7128 CEP104_ZnF zf-C2H2_11
Other DBs
NCBI-GeneID: 100591579
NCBI-ProteinID: XP_030678649
Ensembl: ENSNLEG00000004964
UniProt: A0A2I3H3C3
Position
11:complement(90210592..90791901)
AA seq 1230 aa
MRSKGRARKLATNNECVYGTYPEIPLEDMPDADGVASTPSLNIQEPCSPATSSEAFTPKE
GSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQRSNLKDP
SYGWEILDEFYNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIA
PGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFS
MVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAF
NWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATS
SGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSL
NKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLT
FPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQD
ILKALSKHPSVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSD
LESDIESDKEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVND
SIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPL
KMEPQSPGEVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSR
SRASGTKLTEPRKNHVFGEKKGSNIESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPL
EALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSMFNFRAPPNAL
PENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVR
NIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKED
AYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLLDE
EDEDNDITGKTGKEPVTSNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSALDH
IRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDKESL
HSTSHSSSNVWHSMARAAAESSAIQSISHV
NT seq 3693 nt   +upstreamnt  +downstreamnt
atgagatccaaaggcagggcaaggaaactggccacaaacaatgagtgtgtatatggcacc
taccctgaaatacctttggaagacatgccagatgcagatggagtagccagcactccctcc
ctcaatattcaagagccatgctctcctgccacatccagtgaagcattcactccaaaggag
ggttctccttacaaagcccccatctacatccctgatgatatccccattcctgctgagttt
gaacttcgagagtcaaatatgcctggagcaggactaggaatatggaccaaaaggaagatc
gaagtaggtgaaaagtttgggccttatgtgggagagcagaggtcaaacctgaaagacccc
agttacggatgggagatcttagatgaattttacaatgtgaagttctgcatagatgccagt
caaccagatgttggaagctggctcaagtacattcgattcgctggctgttatgatcagcac
aacctcgttgcatgccagataaatgatcagatattctatagagtagttgcagacattgcg
ccgggagaggagcttctgctgttcatgaagagcgaagactatccccatgaaactatggcg
ccggatatccacgaagaacggcaatatcgctgtgaagactgtgaccagctctttgaatct
aaggctgaactagcagatcaccaaaagtttccatgcagtactcctcactcagcattttca
atggtcgaagaggactttcagcaaaaactcgaaagcgagaatgatctccaagagatacac
acgatccaggagtgtaaggaatgtgaccaagtttttcctgatttgcaaagcctggagaaa
cacatgctgtcacatactgaagagagggaatacaagtgtgatcagtgtcccaaggcattt
aactggaagtccaatttaattcgccaccagatgtcacatgacagtggaaagcactatgaa
tgtgaaaactgtgccaaggttttcacggaccctagcaaccttcagcggcacattcgctct
cagcatgtcggtgcccgggcccatgcatgcccggagtgtggcaaaacgtttgccacttcg
tcgggcctcaaacaacacaagcacatccacagcagtgtgaagccctttatctgtgaggtc
tgccataaatcctatactcagttttcaaacctttgccgtcataagcgcatgcatgctgat
tgcagaacccaaatcaagtgcaaagactgtggacaaatgttcagcactacgtcttcctta
aataaacacaggaggttttgtgagggcaagaaccattttgcggcaggtggattttttggc
caaggcatttcacttcctggaaccccagctatggataaaacgtccatggttaatatgagt
catgccaacccgggccttgctgactattttggcgccaataggcatcctgctggtcttacc
tttccaacagctcctggattttcttttagcttccctggtctgtttccttccggcttgtac
cacaggcctcctttgatacctgctagttctcctgttaaaggactatcaagtactgaacag
acaaacaaaagtcaaagtcccctcatgacacatcctcagatactgccagctacacaggat
attttgaaggcactatctaaacacccatctgtaggggacaataagccagtggagctccag
cccgagaggtcctctgaagagaggccccttgagaaaatcagtgaccagtcagagagtagt
gaccttgatgatgtcagtacaccaagtggcagtgacctggaaacaacctcgggctctgat
ctggaaagtgacattgaaagtgataaagagaaatttaaagaaaatggtaaaatgttcaaa
gacaaagtaagccctcttcagaatctggcttcaataaataataagaaagaatacagcaat
cattccattttctcaccatctttagaggagcagactgcggtgtcaggagctgtgaatgat
tctataaaggctattgcttctattgctgaaaaatactttggttcaacaggactggtgggg
ctgcaagacaaaaaagttggagctttaccttacccttccatgtttcccctcccatttttt
ccagcattctctcaatcaatgtacccatttcctgatagagacttgagatcgttacctttg
aaaatggaaccccaatcaccaggtgaagtaaagaaactgcagaagggcagctctgagtcc
ccctttgatctcaccactaagcgaaaggatgagaagcccttgactccagtcccctccaag
cctccagtgacgcctgccacaagccaagaccagcccctggatctaagtatgggcagtagg
agtagagccagtgggacaaagctgactgagcctcgaaaaaaccatgtgtttggggaaaaa
aaaggaagcaacattgaatcaagacctgcttcagatggttccttgcagcatgcaagaccc
actcctttctttatggaccctatttacagagtagagaaaagaaaactaactgacccactt
gaagctttaaaagagaaatacttgaggccttctccaggattcttgtttcacccacaaatg
tcagctattgaaaacatggcagaaaagctagagagcttcagtgccctgaaacctgaggcc
agtgagctcttacagtcagtgccctctatgttcaacttcagggcacctcccaatgccctg
ccagagaaccttctgcggaagggaaaggagcgctatacctgcagatactgtggcaagatt
tttccaaggtctgcaaacctaacacggcacttgagaacccacacaggagagcagccttac
agatgcaaatactgtgacagatcatttagcatatcttctaacttgcaaaggcatgttcgc
aacatccacaataaagagaagccatttaagtgtcacttatgtgataggtgttttggtcaa
caaaccaatttagacagacacctaaagaaacatgagaatgggaacatgtccggtacagca
acatcgtcgcctcattctgaactggaaagtacaggtgcgattctggatgacaaggaagat
gcttacttcacagaaattcgaaatttcattgggaacagcaaccacggcagccagtctccc
aggaatgtggaggagagaatgaatggcagtcattttaaagatgaaaaggctttggtgacc
agtcaaaattcagacttgctggatgatgaagaagttgaagatgaggtgttgttagatgag
gaggatgaagacaacgatattactggaaaaacaggaaaggaaccagtgacaagtaattta
catgaaggaaaccctgaggatgactatgaagaaaccagtgccctggagatgagttgcaag
acatccccagtgcggtataaagaggaagaatataaaagtggactttctgctttagatcat
ataaggcacttcacagatagcctcaaaatgaggaaaatggaagataatcaatattctgaa
gctgagctgtcttcttttagtacttcccatgtgccagaggaacttaagcagccgttacac
agaaagtccaaatcgcaggcatatgctatgatgctgtcattgtctgacaaggagtccctc
cattctacatcccacagttcttccaacgtgtggcacagtatggccagggctgcagcggaa
tccagtgctatccagtccataagccacgtatga

  All links  
Gene (15)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (18)   
   Pfam (18)   
All databases (40)   

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