KEGG   PATHWAY: cal00564
Entry
cal00564                    Pathway                                
Name
Glycerophospholipid metabolism - Candida albicans
Class
Metabolism; Lipid metabolism
Pathway map
cal00564  Glycerophospholipid metabolism
cal00564

Module
cal_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:cal00564]
cal_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:cal00564]
cal_M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:cal00564]
Other DBs
GO: 0006650
Organism
Candida albicans [GN:cal]
Gene
CAALFM_C210240WA  GPD1; glycerol-3-phosphate dehydrogenase (NAD(+)) [KO:K00006] [EC:1.1.1.8]
CAALFM_C602010CA  GPD2; Gpd2p [KO:K00006] [EC:1.1.1.8]
CAALFM_C406760WA  GUT2; glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
CAALFM_C202890WA  SCT2; bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase [KO:K13507] [EC:2.3.1.15 2.3.1.42]
CAALFM_C300820WA  SCT1; bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase [KO:K13507] [EC:2.3.1.15 2.3.1.42]
CAALFM_C302600CA  SLC1; 1-acylglycerol-3-phosphate O-acyltransferase [KO:K13509] [EC:2.3.1.51]
CAALFM_C207480WA  LPT1; lysophospholipid acyltransferase [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
CAALFM_C300400CA  CaO19.5426; hypothetical protein [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
CAALFM_C104110WA  CaO19.1043; lysophosphatidic acid acyltransferase [KO:K22831] [EC:2.3.1.51]
CAALFM_C300900CA  AYR1; acylglycerone-phosphate reductase [KO:K06123] [EC:1.1.1.101]
CAALFM_C603270CA  AYR2; Ayr2p [KO:K06123] [EC:1.1.1.101]
CAALFM_C304350CA  CaO19.5879; hypothetical protein [KO:K06123] [EC:1.1.1.101]
CAALFM_C201550WA  SMP2; phosphatidate phosphatase [KO:K15728] [EC:3.1.3.4]
CAALFM_C702500CA  DPP3; bifunctional diacylglycerol diphosphate phosphatase/phosphatidate phosphatase [KO:K18693] [EC:3.6.1.75 3.1.3.4]
CAALFM_C111640CA  DPP2; phosphatidate phosphatase [KO:K18693] [EC:3.6.1.75 3.1.3.4]
CAALFM_C111470CA  DPP1; Dpp1p [KO:K18693] [EC:3.6.1.75 3.1.3.4]
CAALFM_C600230WA  CaO19.1181; hypothetical protein [KO:K18693] [EC:3.6.1.75 3.1.3.4]
CAALFM_C200790CA  CaO19.2045; diacylglycerol kinase [KO:K16368] [EC:2.7.1.174]
CAALFM_C602420WA  CaO19.3483; phosphatidylglycerol phospholipase [KO:K18694] [EC:3.1.4.-]
CAALFM_C111590WA  PLD1; phospholipase D [KO:K01115] [EC:3.1.4.4]
CAALFM_C601990WA  PLB1; Plb1p [KO:K13333] [EC:3.1.1.5]
CAALFM_CR09690CA  PLB3; lysophospholipase [KO:K13333] [EC:3.1.1.5]
CAALFM_C108230CA  PLB5; Plb5p [KO:K13333] [EC:3.1.1.5]
CAALFM_C201380WA  PLB4.5; Plb4.5p [KO:K13333] [EC:3.1.1.5]
CAALFM_C602000WA  PLB2; Plb2p [KO:K13333] [EC:3.1.1.5]
CAALFM_CR08300CA  CaO19.6396; lysophospholipase [KO:K14676] [EC:3.1.1.5]
CAALFM_C504510WA  GDE1; glycerophosphocholine phosphodiesterase [KO:K18696] [EC:3.1.4.46]
CAALFM_C305300CA  CaO19.6966; bifunctional choline kinase/ethanolamine kinase [KO:K00866] [EC:2.7.1.32]
CAALFM_C400570CA  PCT1; choline-phosphate cytidylyltransferase [KO:K00968] [EC:2.7.7.15]
CAALFM_C702690CA  CaO19.3695; bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase [KO:K00993] [EC:2.7.8.1]
CAALFM_C701320WA  CaO19.6912; hypothetical protein [KO:K00894] [EC:2.7.1.82]
CAALFM_C200260CA  MUQ1; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
CAALFM_C306570CA  OPI3; bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
CAALFM_CR02540WA  CHO2; phosphatidylethanolamine N-methyltransferase [KO:K16369] [EC:2.1.1.17]
CAALFM_C504100WA  CDS1; phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
CAALFM_C111240CA  CHO1; CDP-diacylglycerol-serine O-phosphatidyltransferase [KO:K17103] [EC:2.7.8.8]
CAALFM_C100610WA  PSD1; phosphatidylserine decarboxylase 1 [KO:K01613] [EC:4.1.1.65]
CAALFM_C504680WA  PSD2; phosphatidylserine decarboxylase 2 [KO:K01613] [EC:4.1.1.65]
CAALFM_C700470CA  PEL1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]
CAALFM_C601340CA  phosphatidylglycerophosphatase [KO:K01094] [EC:3.1.3.27]
CAALFM_C100100CA  CaO19.6100; cardiolipin synthase [KO:K08744] [EC:2.7.8.41]
CAALFM_C209350WA  TAZ1; lysophosphatidylcholine acyltransferase [KO:K13511] [EC:2.3.1.-]
CAALFM_C704090CA  CaO19.7166; hypothetical protein [KO:K13535] [EC:3.1.1.-]
CAALFM_C600490WA  CaO19.4210; carboxylic ester hydrolase [KO:K13535] [EC:3.1.1.-]
CAALFM_C208690CA  CaO19.3607; hypothetical protein [KO:K13535] [EC:3.1.1.-]
CAALFM_C405210WA  CaO19.6860; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
CAALFM_C111490CA  BTA1; Bta1p [KO:K13621]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
cal00010  Glycolysis / Gluconeogenesis
cal00260  Glycine, serine and threonine metabolism
cal00561  Glycerolipid metabolism
cal00562  Inositol phosphate metabolism
cal00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
cal00565  Ether lipid metabolism
cal00620  Pyruvate metabolism
KO pathway
ko00564   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (47)   
   KEGG GENES (47)   
All databases (48)   

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