KEGG   PATHWAY: nca00230
Entry
nca00230                    Pathway                                
Name
Purine metabolism - Nocardioides sp. JS614
Class
Metabolism; Nucleotide metabolism
Pathway map
nca00230  Purine metabolism
nca00230

Module
nca_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:nca00230]
nca_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:nca00230]
nca_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:nca00230]
nca_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:nca00230]
nca_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:nca00230]
nca_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:nca00230]
Other DBs
GO: 0006163 0042278
Organism
Nocardioides sp. JS614 [GN:nca]
Gene
Noca_4438  phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
Noca_0909  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Noca_4316  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Noca_4342  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Noca_3584  formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Noca_4326  phosphoribosylformylglycinamidine synthase subunit II [KO:K23269] [EC:6.3.5.3]
Noca_4333  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
Noca_4332  phosphoribosylformylglycinamidine synthase subunit I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Noca_4315  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Noca_3490  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
Noca_3489  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Noca_4337  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Noca_4341  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Noca_4818  fumarate lyase [KO:K01756] [EC:4.3.2.2]
Noca_4837  fumarate lyase [KO:K01756] [EC:4.3.2.2]
Noca_3583  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Noca_2391  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Noca_2321  5'-Nucleotidase domain protein [KO:K01081] [EC:3.1.3.5]
Noca_2322  Endonuclease/exonuclease/phosphatase [KO:K01081] [EC:3.1.3.5]
Noca_1242  HAD-superfamily hydrolase, subfamily IIA [KO:K02566] [EC:3.1.3.5]
Noca_3521  purine nucleotide phosphorylase [KO:K03783] [EC:2.4.2.1]
Noca_1513  purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
Noca_3059  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Noca_0443  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Noca_3640  IMP dehydrogenase family protein [KO:K00088] [EC:1.1.1.205]
Noca_3645  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Noca_3466  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Noca_1324  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Noca_1636  molybdopterin dehydrogenase, FAD-binding protein [KO:K13481] [EC:1.17.1.4]
Noca_1637  xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K13482] [EC:1.17.1.4]
Noca_3631  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
Noca_4570  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Noca_0829  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Noca_2047  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Noca_2608  IMP dehydrogenase family protein [KO:K26110] [EC:1.7.1.7]
Noca_1141  Guanine deaminase [KO:K01487] [EC:3.5.4.3]
Noca_2436  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Noca_3811  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Noca_1945  putative deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Noca_2392  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Noca_0475  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Noca_2189  RelA/SpoT domain protein [KO:K07816] [EC:2.7.6.5]
Noca_0274  RelA/SpoT domain protein [KO:K07816] [EC:2.7.6.5]
Noca_3492  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Noca_0164  adenylyl cyclase class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
Noca_4344  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Noca_3144  PfkB domain protein [KO:K00856] [EC:2.7.1.20]
Noca_0674  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Noca_3533  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Noca_1299  5'-Nucleotidase domain protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Noca_3884  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Noca_0651  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
Noca_2372  histidine triad (HIT) protein [KO:K19710] [EC:2.7.7.53]
Noca_4208  sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Noca_4207  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Noca_1142  Urate oxidase [KO:K00365] [EC:1.7.3.3]
Noca_2658  putative dimethylaniline monooxygenase [KO:K22879] [EC:1.14.13.113]
Noca_1143  Transthyretin [KO:K07127] [EC:3.5.2.17]
Noca_1144  putative urate oxidase, N-terminal [KO:K16840] [EC:4.1.1.97]
Noca_0094  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
Noca_4086  amidohydrolase [KO:K01466] [EC:3.5.2.5]
Noca_1504  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Noca_2426  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
nca00030  Pentose phosphate pathway
nca00220  Arginine biosynthesis
nca00250  Alanine, aspartate and glutamate metabolism
nca00260  Glycine, serine and threonine metabolism
nca00340  Histidine metabolism
nca00630  Glyoxylate and dicarboxylate metabolism
nca00730  Thiamine metabolism
nca00740  Riboflavin metabolism
nca00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (63)   
   KEGG GENES (63)   
All databases (64)   

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