KEGG   Pongo abelii (Sumatran orangutan): 100461139
Entry
100461139         CDS       T01416                                 

Definition
(RefSeq) cytochrome P450 11B2, mitochondrial isoform X1
  KO
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00140  Steroid hormone biosynthesis
pon01100  Metabolic pathways
pon04925  Aldosterone synthesis and secretion
Module
pon_M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100461139
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    100461139
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:pon00199]
    100461139
Enzymes [BR:pon01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     100461139
    1.14.15.5  corticosterone 18-monooxygenase
     100461139
Cytochrome P450 [BR:pon00199]
 Cytochrome P450, animal type
  CYP11 family
   100461139
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 100461139
NCBI-ProteinID: XP_024107318
Position
8
AA seq 503 aa
MALRAKAEVCMAVPWLSLQRARALGTRAARSPRTVLPFEAMPQRPGNRWLRLLQIWREQG
YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPRRMILEPWVAYR
QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNA
RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM
PRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLNAELS
LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQALRQESLAAAASISEHPQKATT
ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNPALFPRP
ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLIQED
IKMVYSFILRPGTSPLLTFRAIN
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggcactcagggcaaaggcagaggtgtgcatggcagtgccctggctgtccctgcaaagg
gcacgggcactgggcactagagccgctcggtcccctaggacggtgctgccctttgaagcc
atgccccagcgtccaggcaacaggtggctgaggctgctgcagatctggagggagcagggt
tatgagcacctgcacctggagatgcaccagaccttccaggagctggggcccattttcagg
tacaacttgggaggaccacgcatggtgtgtgtgatgctgccagaggacgtggagaagctg
caacaggtggacagcctacatcctcgcaggatgatcctggagccctgggtggcctataga
caacatcgtgggcacaaatgtggcgtgttcttgctgaatgggcctgaatggcgcttcaac
cgattgcggctgaacccagatgtgctgtctcccaaggccgtgcagaggttcctcccgatg
gtggatgcggtggccagggacttctcccaggccttgaagaagaaggtgctgcagaacgcc
cgggggagcctgaccctggacgtccagcccagcatcttccactacaccatagaagccagc
aacttagctctttttggagagcggctgggcctggttggccacagccccagctctgccagc
ctgaacttcctccatgccctggaggtcatgttcaaatccaccgtccagctcatgttcatg
cccaggagcctgtctcgctggaccagccccaaggtgtggaaggagcactttgaggcctgg
gactgcatcttccagtacggtgacaactgtatccagaaaatctatcaggaactggccttc
aaccgccctcaacactacacaggcattgtggcggagctcctgttgaatgcggaactgtca
ctagaagccatcaaggccaactctatggaactcactgcagggagcgtggacacgacggcg
tttcccttgctgatgacgctctttgagctggctcggaaccccgatgtgcagcaggccctg
cgccaggagagcctggctgctgcagccagcatcagtgaacatccccagaaggcaaccacc
gagctgcccttgctgcgggcggccctcaaggagaccttgaggctctaccctgtgggtctg
tttttggagcgagtggtgagctcagacttggtgcttcagaactaccacatcccagctggg
acattggtgcaggttttcctctactcgctgggtcggaaccccgccttgttcccgaggcct
gagcggtataatccccagcgctggctagacatcaggggctccggcaggaacttccaccac
gtgccctttggctttggcatgcgccagtgcctggggcggcgcctggcagaagcggagatg
ctgctgctgctgcaccacgtgctgaagcacttcctggtggagacactaatccaagaggac
ataaagatggtctacagcttcatattgaggcccggcacgtcccccctcctcactttcaga
gcgatcaactag

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