KEGG   Pan paniscus (bonobo): 100967540
Entry
100967540         CDS       T02283                                 

Gene name
IL3RA
Definition
(RefSeq) interleukin 3 receptor subunit alpha
  KO
K04737  interleukin 3 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04210  Apoptosis
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100967540 (IL3RA)
   04151 PI3K-Akt signaling pathway
    100967540 (IL3RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100967540 (IL3RA)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100967540 (IL3RA)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100967540 (IL3RA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967540 (IL3RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100967540 (IL3RA)
   04090 CD molecules [BR:pps04090]
    100967540 (IL3RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL3 receptor family
   100967540 (IL3RA)
CD molecules [BR:pps04090]
 Proteins
  100967540 (IL3RA)
SSDB
Motif
Pfam: IL3Ra_N Tissue_fac
Other DBs
NCBI-GeneID: 100967540
NCBI-ProteinID: XP_008965282
Position
X
AA seq 252 aa
MVLLWLTLLLIAMPCLLQTKEDKNWRKNAHPNPPITNLRMKAKAQQLTWDLNRNVTDIEC
VKDADYSMPESQNQYCSHRWCHDYLVSAPKSAVGFEKVFFSLLEILTPPNMTAKCNKTHS
FMHWKMRSHFNRKFRYELQIQKRMQPVITEQVSVPYPQPLYLTLQRSFAPSWHCLSWTRR
VPDDELVGAGFRAGPFLFPPRYLLIQRLFPRIPHMKDPIGDSFQNDKLVVWEAGKASLEE
CLVTEVQVVQKT
NT seq 759 nt   +upstreamnt  +downstreamnt
atggtcctcctttggctcacgctgctcctgatcgccatgccctgtctcctgcaaacgaag
gaagataagaactggagaaaaaatgcacatccaaacccaccaatcacgaacctaaggatg
aaagcaaaggctcagcagttgacctgggaccttaacagaaatgtgaccgatatcgagtgt
gttaaagacgccgactattctatgccggaatctcagaaccaatactgctcccatcgctgg
tgtcatgactacctggtttctgccccgaagtcagctgtgggatttgaaaaagtgtttttc
tcgttgctagagatattaactccacccaacatgactgcaaagtgtaataagacacattcc
tttatgcactggaaaatgagaagtcatttcaatcgcaaatttcgctatgagcttcagata
caaaagagaatgcagcctgtaatcacagagcaggtgagtgttccctacccccagccgctg
tacttgacattgcaaaggtcttttgctccgtcctggcactgcctgtcctggacacgccgt
gtcccagatgatgagctggtcggtgctgggttcagagctgggccatttctctttcctccg
aggtatctgctgatacagagactctttccccgcatccctcacatgaaagaccccatcggt
gacagcttccaaaacgacaagctggtggtctgggaggcgggcaaagccagcctggaggag
tgtctggtgactgaagtacaggtcgtgcagaaaacttga

KEGG   Pan paniscus (bonobo): 100967748
Entry
100967748         CDS       T02283                                 

Gene name
IL13RA1
Definition
(RefSeq) interleukin 13 receptor subunit alpha 1
  KO
K05076  interleukin 13 receptor alpha-1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100967748 (IL13RA1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100967748 (IL13RA1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967748 (IL13RA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100967748 (IL13RA1)
   04090 CD molecules [BR:pps04090]
    100967748 (IL13RA1)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL3 receptor family
   100967748 (IL13RA1)
CD molecules [BR:pps04090]
 Proteins
  100967748 (IL13RA1)
SSDB
Motif
Pfam: Il13Ra_Ig IL6Ra-bind fn3 EpoR_lig-bind LIFR_N Tissue_fac LIFR_D2
Other DBs
NCBI-GeneID: 100967748
NCBI-ProteinID: XP_008963323
Position
X
AA seq 572 aa
MIATQPEAKGGDLDAKTQRPFLFQRLKYDSVLVSSRTQPLAPPRPRKCAGSGDAGSATRR
EEAQAAPGLGGDVEPPEPPEPPAPRSASSGRSRRLRLPEAGGRGGPSRLRRPPASRAAES
GSGRGSEGGGDCQGSSPAGLRGERLHGVAGAALRAVGAAALRRRRGRGRGATPTETQPPV
TNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERIC
LQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPD
TNYTLYYWHRSLEKIHQCENIYREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKP
SFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVF
YVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMS
IGKKRNSTLYITMLLIVPVIVAGAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDD
TLHWKKYDIYEKQTKEETDSVVLIENLKKASQ
NT seq 1719 nt   +upstreamnt  +downstreamnt
atgatagcaacgcagccagaagccaaaggaggggacctggatgctaagacacagaggccc
ttcctctttcagagactgaagtatgactctgtcctggtgtccagcaggacacagccccta
gcacctccgaggccccgcaagtgtgctggcagcggcgacgccggctccgccacgcggagg
gaggaggcccaggcagcgcccggactgggcggcgacgtggagccgccagagccgccagag
ccgccggcgccccgctccgcctcctccggccgctctcgccggctcaggttacctgaggcc
ggtgggcggggcggcccttcccgtctgcgccggcccccagcctccagggcggcggagtcg
ggaagtggaagagggagcgaaggaggcggggactgccaaggctccagcccggccgggctc
cgaggcgagaggctgcatggagtggccggcgcggctctgcgggctgtgggcgctgctgct
ctgcgccggcggcgggggcgggggcggggcgccacgcctacggaaactcagccacctgtg
acaaatttgagtgtctctgttgaaaacctctgcacagtaatatggacatggaatccaccc
gagggagccagctcaaattgtagtctatggtattttagtcattttggcgacaaacaagat
aagaaaatagctccggaaactcgtcgttcaatagaagtacccctgaatgagaggatttgt
ctgcaagtggggtcccagtgtagcaccaatgagagtgagaagcctagcattttggttgaa
aaatgcatctcacccccagaaggtgatcctgagtctgctgtgactgagcttcaatgcatt
tggcacaacctgagctacatgaagtgttcttggctccctggaaggaataccagtcccgac
actaactatactctctactattggcacagaagcctggaaaaaattcatcaatgtgaaaac
atctatagagaaggccaatactttggttgttcctttgatctgaccaaagtgaaggattcc
agttttgaacaacacagtgtccaaataatggtcaaggataatgcaggaaaaattaaacca
tccttcaatatagtgcctttaacttcccgtgtgaaacctgatcctccacatattaaaaac
ctctccttccacaatgatgacctatatgtgcaatgggagaatccacagaattttattagc
agatgcctattttatgaagtagaagtcaataacagccaaactgagacacataatgttttc
tacgtccaagaggctaaatgtgagaatccagaatttgagagaaatgtggagaatacatct
tgtttcatggtccctggtgttcttcctgatactttgaacacagtcagaataagagtcaaa
acaaataagttatgctatgaggatgacaaactctggagtaattggagccaagaaatgagt
ataggtaagaagcgcaattccacactctacataaccatgttactcattgttccagtcatc
gtcgcaggtgcaatcatagtacttctgctttacctaaaaaggctcaagattattatattc
cctccaattcctgatcctggcaagatttttaaagaaatgtttggagaccagaatgatgat
actctgcactggaagaagtacgacatctatgagaagcaaaccaaggaggaaaccgactct
gtagtgctgatagaaaacctgaagaaagcctctcagtga

KEGG   Pan paniscus (bonobo): 100969808
Entry
100969808         CDS       T02283                                 

Gene name
IL4R
Definition
(RefSeq) interleukin 4 receptor
  KO
K05071  interleukin 4 receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps05200  Pathways in cancer
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100969808 (IL4R)
   04151 PI3K-Akt signaling pathway
    100969808 (IL4R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100969808 (IL4R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100969808 (IL4R)
   04658 Th1 and Th2 cell differentiation
    100969808 (IL4R)
   04659 Th17 cell differentiation
    100969808 (IL4R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100969808 (IL4R)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100969808 (IL4R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100969808 (IL4R)
   04090 CD molecules [BR:pps04090]
    100969808 (IL4R)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100969808 (IL4R)
CD molecules [BR:pps04090]
 Proteins
  100969808 (IL4R)
SSDB
Motif
Pfam: IL4Ra_N fn3
Other DBs
NCBI-GeneID: 100969808
NCBI-ProteinID: XP_008958142
UniProt: A0A2R9C7J4
Position
16
AA seq 825 aa
MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL
LYQLVFLLSEAHTCVPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH
VKPRAPGNLTVYTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL
EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVF
CIVILVVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCP
HWKNCLTKLLPCFLEHNMKRDEDPHKAAKEMPFQGSGKSAWCPVEISKTVLWPESISVVR
CVELFEAPVECEEEEEVEEEKGSFCASPESSRDDCQEGREGIVARLTESLFLDLLGEENG
GFCQQDMGESCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPD
NLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPQLARHLEEVEPEMPCVPQLSEPT
TVPPPEPETWEQILRRNVLQHGAAAAPVSAPTSGYREFIHAVEQGGTQASAVVGLGPPGE
AGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDRE
PPHSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHL
CGHLKQCHGQEDGGQTPVVASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASL
APSGISEKIKPSSSFHPAPGNAQSSSQTPKIVNFVSVGPTYMRVS
NT seq 2478 nt   +upstreamnt  +downstreamnt
atggggtggctttgctctgggctcctgttccctgtgagctgcctggtcctgctgcaggtg
gcaagctctgggaacatgaaggtcctgcaggagcccacctgcgtctctgactacatgagc
atctctacttgcgagtggaagatgaatggtcccaccaattgcagcaccgagctccgcctg
ttgtaccagctggtttttctgctctccgaagcccacacgtgtgtccccgagaacaacgga
ggcgcggggtgcgtgtgccacctgctcatggatgacgtggtcagtgcggacaattataca
ctggacctgtgggctgggcagcagctgctgtggaagggctccttcaagcccagcgagcat
gtgaaacccagggccccaggaaacctgacagtttacaccaatgtctccgacactctgctg
ctgacctggagcaacccgtatccccctgacaattacctgtataatcatctcacctatgca
gtcaacatttggagtgaaaacgacccggcagatttcagaatctataacgtgacctaccta
gaaccgtccctccgcatcgcagccagcaccctgaagtctgggatttcctacagggcacgg
gtgagggcctgggctcagtgctataacaccacctggagtgagtggagccccagcaccaag
tggcacaactcctacagggagcccttcgagcagcacctcctgctgggcgtcagcgttttc
tgcattgtcatcctggtcgtctgcctgttgtgctatgtcagcatcaccaagattaagaaa
gaatggtgggatcagattcccaacccagcccgcagccgcctcgtggctataataatccag
gatgctcaggggtcacagtgggagaagcggtcccgaggccaggaaccagccaagtgccca
cactggaagaattgtcttaccaagctcttgccctgttttctggagcacaacatgaaaagg
gatgaagatcctcacaaggctgccaaagagatgcctttccagggctctggaaaatcagca
tggtgcccagtggagatcagcaagacagtcctctggccagagagcatcagcgtggtgcga
tgcgtggagttgtttgaggccccggtggagtgtgaggaggaggaggaggtagaggaagaa
aaagggagcttctgtgcatcgcctgagagcagcagggatgactgccaggagggaagggag
ggcattgtggcccggctaacagagagcctgttcctggacctgctcggagaggagaatggg
ggcttttgccagcaggacatgggggagtcatgccttctcccaccttcgggaagtacgagt
gctcacatgccctgggatgagttcccaagtgcagggcccaaggaggcacctccctggggc
aaggagcagcctctccacctggagccaagtcctcctgccagcccgacccagagtccagac
aacctgacttgcacagagacgcccctcgtcatcgcaggcaaccctgcttaccgcagcttc
agcaactccctgagccagtcaccgtgtcccagagagctgggtccagacccacagctggcc
agacacctggaggaagtagaacccgagatgccctgtgtcccccagctctctgagccaacc
actgtgcccccacctgagccagaaacctgggagcagatcctccgccgaaatgtcctccag
catggggcagctgcagcccccgtctcggcccccaccagtggctatcgggagtttatacat
gcagtggagcagggtggcacccaggccagtgcggtggtgggcttgggtcccccaggagag
gctggttacaaggccttctcaagcctgcttgccagcagtgctgtgtccccggagaaatgt
gggtttggggctagcagtggggaagaggggtataagcctttccaagacctcattcctggc
tgccctggggaccctgccccagtccctgtccccttgttcacctttggactggacagggag
ccacctcacagtccgcagagctcacatctcccaagcagctccccagagcacctgggtctg
gagccgggggaaaaggtagaggacatgccaaagcccccacttccccaggagcaggccaca
gacccccttgtggacagcctgggcagtggcattgtctactcagccctcacctgccacctg
tgcggccacctgaaacagtgtcatggccaggaggatggtggccagacccctgtcgtggcc
agtccctgctgtggctgctgctgtggagacaggtcctcgccccctacaacccccctgagg
gccccagacccctctccaggtggggttccactggaggccagcctgtgtccggcctccctg
gcaccctcgggcatctcagagaagattaaaccctcatcgtccttccatcctgcccctggc
aatgctcagagctcaagccagacccccaaaatcgtgaactttgtctccgtgggacccaca
tacatgagggtctcttag

KEGG   Pan paniscus (bonobo): 100970355
Entry
100970355         CDS       T02283                                 

Gene name
IL21R
Definition
(RefSeq) interleukin 21 receptor
  KO
K05075  interleukin 21 receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04659  Th17 cell differentiation
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100970355 (IL21R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100970355 (IL21R)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100970355 (IL21R)
 09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease
    100970355 (IL21R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100970355 (IL21R)
   04090 CD molecules [BR:pps04090]
    100970355 (IL21R)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100970355 (IL21R)
CD molecules [BR:pps04090]
 Proteins
  100970355 (IL21R)
SSDB
Motif
Pfam: IL4Ra_N Phage_holin_T
Other DBs
NCBI-GeneID: 100970355
NCBI-ProteinID: XP_003807810
UniProt: A0A2R9C6C4
Position
16
AA seq 538 aa
MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLILTWQDQYEELKD
EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFVPLYKGCSGDFKKWVGAPFTGSS
LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLG
AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
NT seq 1617 nt   +upstreamnt  +downstreamnt
atgccgcgtggctgggccgcccccttgctcctgctgctgctccagggaggctggggctgc
cccgacctcgtctgctacaccgattacctccagacggtcatttgcatcctggagatgtgg
aacctccaccccagcacgctcatccttacctggcaagaccagtatgaagagctgaaggac
gaggccacctcctgcagcctccacaggtcggcccacaatgccacgcatgccacctacacc
tgccacatggatgtattccacttcatggccgacgacattttcagtgtcaacatcacagac
cagtctggcaactactcccaggagtgtggcagctttctcctggctgagagcatcaagccg
gctccccctttcaacgtgactgtgaccttctcaggacagtataatatctcctggcgctca
gattacgaagaccctgccttctacatgctgaagggcaagcttcagtatgagctgcagtac
aggaaccggggagacccctgggctgtgagtccgaggagaaagctgatctcagtggactca
agaagtgtctccctcctccccctggagttccgcaaagactcgagctatgagctgcaggtg
cgggcagggcccatgcctggctcctcctaccaggggacctggagtgaatggagtgacccg
gtcatctttcagacccagtcagaggagttaaaggaaggctggaaccctcacctgctgctt
ctcctcctgcttgtcatagtcttcattcctgccttctggagcctgaagacccatccattg
tggaggctatggaagaagatatgggccgtccccagccctgagcggttcttcgtgcccctg
tacaagggctgcagcggagacttcaagaaatgggtgggtgcacccttcactggctctagc
ctggagctgggaccctggagcccagaggtgccctccaccctggaggtgtacagctgccac
ccaccacggagcccggccaagaggctgcagctcacggagctacaagaaccagcagagctg
gtggagtctgacggtgtgcccaagcccagcttctggccgacagcccagaactcggggggc
tcagcttacagtgaggagagggaccggccgtacggcctggtgtccattgacacagtgact
gtgctagatgcagaggggccatgcacctggccctgcagctgtgaggatgacggctaccca
gccctggacctggatgctggcctggagcccagcccaggcctagaggacccactcttgggt
gcagggaccacagtcctctcctgtggctgtgtctcagctggcagccctgggctgggaggg
cccctgggaagcctcctggacagactaaagccaccccttgcagatggggaggactgggct
gggggactgccctggggtggccggtcacctggaggggtctcagagagtgaggcaggctca
cccctggctggcctggatatggacacgtttgacagtggctttgtgggctctgactgcagc
agccctgtggagtgtgacttcaccagccccggggatgaaggacccccccggagctacctc
cgccagtgggtggtcattcctccgccactttcgagccctggaccccaggccagctag

KEGG   Pan paniscus (bonobo): 100970737
Entry
100970737         CDS       T02283                                 

Gene name
LIFR
Definition
(RefSeq) leukemia inhibitory factor receptor alpha
  KO
K05058  leukemia inhibitory factor receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04550  Signaling pathways regulating pluripotency of stem cells
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100970737 (LIFR)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100970737 (LIFR)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100970737 (LIFR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100970737 (LIFR)
   04090 CD molecules [BR:pps04090]
    100970737 (LIFR)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100970737 (LIFR)
CD molecules [BR:pps04090]
 Proteins
  100970737 (LIFR)
SSDB
Motif
Pfam: LIFR_D2 LIFR_N fn3 EpoR_lig-bind Pur_ac_phosph_N IL6Ra-bind TMEM154
Other DBs
NCBI-GeneID: 100970737
NCBI-ProteinID: XP_008961575
UniProt: A0A2R9C1G2
Position
5
AA seq 1097 aa
MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSAFILLYLMNQVNSQKKGAPHDLKCVTNNL
QVWNCSWKASSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALAHGDYEITINSLHDFGS
STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHHSNVIWEIKVQRKE
SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDSLHFSGLKEWSDWSP
VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCQIEIKKSNSVQEQR
NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGVRYNFFLYGCRNQGYQLLRSMIGYIE
ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
NGGGWSFTNFFQNKPND
NT seq 3294 nt   +upstreamnt  +downstreamnt
atgatggatatttacgtatgtttgaaacgaccatcctggatggtggacaataaaagaatg
aggactgcttcaaatttccagtggctgttatcagcatttattcttctatatctaatgaat
caagtaaatagccagaaaaagggggctcctcatgatttgaagtgtgtaactaacaatttg
caagtgtggaactgttcttggaaagcatcctctggaacaggccgtggtactgattatgaa
gtttgcattgaaaacaggtcccgttcttgttatcagttggagaaaaccagtattaaaatt
ccagctcttgcacatggtgattatgaaataacaataaattctctacatgattttggaagt
tctacaagtaaattcacactaaatgaacaaaacgtttccttaattccagatactccagag
atcttgaatttgtctgctgatttctcaacctctacattatacctaaagtggaacgacagg
ggttcagtttttccacaccactcaaatgttatctgggaaattaaagttcaacgtaaagag
agtatggagctcgtaaaattagtgacccacaacacaactctgaatggcaaagatacactt
catcactggagttgggcctcagatatgcccttggaatgtgccattcattttgtggaaatt
agatgctacattgacagtcttcatttttctggtctcaaagagtggagtgactggagccct
gtgaagaacatttcttggatacctgattctcagactaaggtttttcctcaagataaagtg
atacttgtaggctcagacataacattttgttgtgtgagtcaagaaaaagtgttatcagca
ctgattggccatacaaactgccccttgatccatcttgatggggaaaatgttgcaatcaag
attcgtaatatttctgtttctgcaagtagtggaacaaatgtagtttttacaaccgaagat
aacatatttggaacggttatttttgctggatatccaccagatactcctcaacaactgaat
tgtgagacacatgatttaaaagaaattatatgtagttggaatccaggaagggtgacagcg
ttggtgggcccacgtgctacaagctacactttagttgaaagtttttcaggaaaatatgtt
agacttaaaagagctgaagcacctacaaacgaaagctatcaattattatttcaaatgctt
ccaaatcaagaaatatataattttactttgaatgctcacaatccgctgggtcgatcacaa
tcaacaattttagttaatataactgaaaaagtttatccccatactcctacttcattcaaa
gtgaaggatattaattcaacagctgttaaactttcttggcatttaccaggcaactttgca
aagattaattttttatgtcaaattgaaattaagaaatctaattcagtacaagaacagcgg
aatgtcacaatcaaaggagtagaaaattcaagttatcttgttgctctggacaagttaaat
ccatacactctatatacttttcggattcgttgttctactgaaactttctggaaatggagc
aaatggagcaataaaaaacaacatttaacgacagaagccagtccttcaaaggggcctgat
acttggagagagtggagttctgatggaaaaaatttaataatctattggaagcctttaccc
attaatgaagctaatggaaaaatactttcctacaatgtatcgtgttcatcagatgaggaa
acacagtccctttctgaaatccctgatcctcagcacaaagcagagatacgacttgataag
aatgactacatcatcagcgtagtggctaaaaattctgtgggctcatcaccaccttccaaa
atagcgagtatggaaattccaaatgatgatctcaaaatagaacaagttgttgggatggga
aaggggattctcctcacctggcattacgaccccaacatgacttgcgactacgtcattaag
tggtgtaactcgtctcggtcggaaccatgccttatggactggagaaaagttccctcaaac
agcactgaaactgtaatagaatctgatgagtttcgaccaggtgtaagatataattttttc
ctgtatggatgcagaaatcaaggatatcaattattacgctccatgattggatatatagaa
gaattggctcccattgttgcaccaaattttactgttgaggatacttctgcagattcgata
ttagtaaaatgggaagacattcctgtggaagaacttagaggctttttaagaggatatttg
ttttactttggaaaaggagaaagagacacatctaagatgagggttttagaatcaggtcgt
tctgacataaaagttaagaatattactgacatatcccagaagacactgagaattgctgat
cttcaaggtaaaacaagttaccacctggtcttgcgagcctatacagatggtggagtgggc
ccggagaagagtatgtacgtggtgacaaaggaaaattctgtgggattaattattgccatt
ctcatcccagtggcagtggctgtcattgttggagtggtgacaagtatcctttgctatcgg
aaacgagaatggattaaagaaaccttctaccctgatattccaaatccagaaaactgtaaa
gcattacagtttcaaaagagtgtctgtgagggaagcagtgctcttaaaacattggaaatg
aatccttgtaccccaaataatgttgaggttctggaaactcgatcagcatttcctaaaata
gaagatacagaaataatttccccagtagctgagcgtcctgaagatcgctctgatgcagag
cctgaaaaccatgtggttgtgtcctattgtccacccatcattgaggaagaaataccaaac
ccagccgcagatgaagctggagggactgcacaggttatttacattgatgttcagtcgatg
tatcagcctcaagcaaaaccagaagaagaacaagaaaatgatcctgtaggaggggcaggc
tataagccacagatgcacctccccattaattctactgtggaagatatagctgcagaagag
gacttagataaaactgcgggttacagacctcaggccaatgtaaatacatggaatttagtg
tctccagactctcctagatccatagacagcaacagtgagattgtctcatttggaagtcca
tgctccattaattcccgacaatttttgattcctcctaaagatgaagactctcctaaatct
aatggaggagggtggtcctttacaaacttttttcagaacaaaccaaacgattaa

KEGG   Pan paniscus (bonobo): 100972031
Entry
100972031         CDS       T02283                                 

Gene name
IL6R
Definition
(RefSeq) interleukin 6 receptor
  KO
K05055  interleukin 6 receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04066  HIF-1 signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04659  Th17 cell differentiation
pps04932  Non-alcoholic fatty liver disease
pps05163  Human cytomegalovirus infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100972031 (IL6R)
   04066 HIF-1 signaling pathway
    100972031 (IL6R)
   04151 PI3K-Akt signaling pathway
    100972031 (IL6R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100972031 (IL6R)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100972031 (IL6R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100972031 (IL6R)
   04659 Th17 cell differentiation
    100972031 (IL6R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100972031 (IL6R)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100972031 (IL6R)
   05163 Human cytomegalovirus infection
    100972031 (IL6R)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100972031 (IL6R)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100972031 (IL6R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100972031 (IL6R)
   04090 CD molecules [BR:pps04090]
    100972031 (IL6R)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100972031 (IL6R)
CD molecules [BR:pps04090]
 Proteins
  100972031 (IL6R)
SSDB
Motif
Pfam: IL6Ra-bind ig Ig_3 Ig_2 fn3 I-set Ig_5
Other DBs
NCBI-GeneID: 100972031
NCBI-ProteinID: XP_003817158
UniProt: A0A2R9A372
Position
1
AA seq 468 aa
MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
CFRKSPLSNVVCEWGPRSTPSQTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
GEWSEWSPEAMGTPWTESRSPPAENEVSTPTQALTTNKDDDNILFRDSANATSLPVQDSS
SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP
TPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR
NT seq 1407 nt   +upstreamnt  +downstreamnt
atgctggccgtcggctgcgcgctgctggctgctctgctggccgcgccgggagcggcgctg
gccccaaggcgctgccctgcgcaggaggtggcgagaggtgtgctgaccagtctgccagga
gacagcgtgactctgacctgcccgggggtagagccggaagacaatgccactgttcactgg
gtgctcaggaagccggctgcaggctcccaccccagcagatgggctggcatgggaaggagg
ctgctgttgaggtcggtgcagctccacgactctggaaactattcatgctaccgggccggc
cgcccagctgggactgtgcacttgctggtggatgttccccccgaggagccccagctctcc
tgcttccggaagagccccctcagcaacgttgtttgtgagtggggtcctcggagcacccca
tcccagacgaccaaggctgtgctcttggtgaggaagtttcagaacagtccggccgaagac
ttccaggagccgtgccagtattcccaggagtcccagaagttctcctgccagttggcagtc
ccggagggagacagctctttctacatagtgtccatgtgcgtcgccagtagtgtcgggagc
aagttcagcaaaactcaaacctttcagggttgtggaatcttgcagcctgatccgcctgcc
aacatcacagtcactgctgtggccagaaacccccgctggctcagtgtcacctggcaagac
ccccactcctggaactcatctttctacagactacggtttgagctcagatatcgggctgaa
cggtcaaagacattcacaacatggatggtcaaggacctccagcatcactgtgtcatccac
gacgcctggagcggcctgaggcacgtggtgcagcttcgtgcccaggaggagttcgggcaa
ggcgagtggagcgagtggagcccggaggccatgggcacgccttggacagaatccaggagt
cctccagctgagaacgaggtgtccacccccacgcaggcacttactactaataaagacgat
gataatattctcttcagagattctgcaaatgcgacaagcctcccagtgcaagattcttct
tcagtaccactgcccacattcctggttgctggagggagcctggccttcggaacgctcctc
tgcattgccattgttctgaggttcaagaagacgtggaagctgcgggctctgaaggaaggc
aagacaagcatgcatccgccgtactctttggggcagctggtcccggagaggcctcgaccc
accccagtgcttgttcctctcatctccccaccggtgtcccccagcagcctggggtctgac
aatacctcgagccacaaccgaccagatgccagggacccacggagcccttatgacatcagc
aatacagactacttcttccccagatag

KEGG   Pan paniscus (bonobo): 100972785
Entry
100972785         CDS       T02283                                 

Gene name
OSMR
Definition
(RefSeq) oncostatin M receptor
  KO
K05057  oncostatin M receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100972785 (OSMR)
   04151 PI3K-Akt signaling pathway
    100972785 (OSMR)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100972785 (OSMR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100972785 (OSMR)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100972785 (OSMR)
SSDB
Motif
Pfam: fn3 LIFR_D2 EpoR_lig-bind Pur_ac_phosph_N
Other DBs
NCBI-GeneID: 100972785
NCBI-ProteinID: XP_003811010
Position
5
AA seq 979 aa
MALFAIFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYH
QELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLHWSWESELPLECATHFVRIKSVVDD
AKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCY
LEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEP
KDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQ
DSQETYNFTLTAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSMRN
NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG
QNFTTLEAAPSEAPDVWRIVNLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSR
SELHSIPAPANSTKLILDRCSYQICVTANNSVGASPASVIVISADPENKEVEEERIAGTE
GGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFR
IYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGY
HVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSA
GEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKS
SILSLIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYL
LPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALXKN
YINSLGEIPAGETSLNYVSQLASPMFGDKDSLPTNPVEPPHCSEYKMQMAVSLRLALPPP
TENSSLSSITLLDPGEHYC
NT seq 2940 nt   +upstreamnt  +downstreamnt
atggctctatttgcaatctttcagacgacattcttcttaacgttgctgtccttgaggact
taccagagtgaagtcttggctgaacgtttaccattgactcctgtatcacttaaagtttcc
accaattctacgcgtcagagtttgcacttacaatggactgtccacaaccttccttatcat
caggaattgaaaatggtatttcagatccagatcagtaggattgaaacatccaatgtcatc
tgggtggggaattacagcaccactgtgaagtggaaccaggttctgcattggagctgggaa
tccgagctccctttggaatgtgccacacactttgtaagaataaagagtgtggtggatgat
gccaagttccctgagccaaatttctggagcaactggagttcctgggaggaagtcagtgta
caagattctactggacaggatatattgttcgttttccctaaagataagctggtggaagaa
ggcaccaatgttaccatttgttacgtttctaggaacattcaaaataatgtatcctgttat
ttggaagggaaacagattcatggagaacaacttgatccacatgtaactgcattcaacttg
aatagtgtgcctttcattaggaataaagggacaaatatctattgtgaggcaagtcaagga
aatgtcagtgaaggcatgaaaggcatcgttctttttgtctcaaaagtacttgaggagccc
aaggacttttcttgtgaaaccgaggacttcaagactttgcactgtacttgggatcctggg
acggacactgccttggggtggtctaaacaaccttcccaaagctacactttatttgaatca
ttttctggggaaaagaaactttgtacacacaaaaactggtgtaattggcaaataactcaa
gactcacaagaaacctataacttcacactcacagctgaaaattacttaaggaagagaagt
gtcaatatcctttttaacctgactcatcgagtttatttaatgaatccttttagtgtcaac
tttgaaaatgtaaatgccacaaacgccatcatgacctggaaggtgcactccatgaggaat
aatttcacatatttgtgtcagattgaactccatggtgaaggaaaaatgatgcaatacaat
gtttccatcaaggtgaacggtgagtacttcttaagtgaactggaacctgccacagagtac
atggcgcgagtacgctgtgctgatgccagccacttctggaaatggagtgaatggagtggt
cagaacttcaccacacttgaagctgctccctcagaggcccctgatgtctggagaattgtg
aacttggagccaggaaatcatactgtgaccttattctggaagccattatcaaaactgcat
gccaatggaaagatcctgttctataatgtagttgtagaaaacctagacaaaccatccagg
tcagagctccattccattccggcgccagccaacagcacaaaactaatccttgacaggtgt
tcctaccaaatctgcgtcacagccaacaacagtgtgggtgcttctcctgcttctgtaata
gtcatctctgcagaccccgaaaacaaagaggttgaggaagaaagaattgcaggcacagag
ggtggattctctctgtcttggaaaccccaacctggagatgttataggctatgttgtggac
tggtgtgaccatacccaggatgtgctcggtgatttccagtggaagaatgtaggtcccaat
accacaagcacagtcattagcacagatgcttttaggccaggagttcgatacgacttcaga
atttatgggttatctacaaaaaggattgcttgtttattagagaaaaaaacaggatactct
caggaacttgctccttcagacaaccctcacgtgctggtggatacgttgacatcccactcc
ttcactctgagttggaaagattactctactgaatctcaacctggttttatacaagggtac
catgtctatctgaaatccaaggcgaggcagtgccacccacgatttgaaaaggcagttctt
tcagatggttcagaatgttgcaaatacaaaattgacaacccagaagaaaaggcattgatt
gtggacaacctaaagccagaatccttctatgagtttttcatcactccattcactagtgct
ggcgaaggccccagtgctacgttcacgaaggtcacgactccggatgaacactcctcgatg
ctgattcatatcctactgcccatggttttctgcgtcttgctcatcatggtcatgtgctac
ttgaaaagtcagtggatcaaggagacctgttatcctgacatccctgacccttacaagagc
agcatcctgtcattaataaaattcaaggagaaccctcacctaataataatgaatgtcagt
gactgtatcccagatgctattgaagttgtaagcaagccagaagggacaaagatacagttc
ctaggcactaggaagtcactcacagaaaccgagttgactaagcctaactacctttatctc
cttccaacagaaaagaatcactctggccctggcccctgcatctgttttgagaacttgacc
tataaccaggcagcttctgactctggctcttgtggccatgttccagtatccccaaaagcc
ccaagtatgctgggactaatgacctcacctgaaaatgtactaaaggcactangaaaaaac
tacattaactccctgggagaaatcccagctggagaaacaagtttgaattatgtgtcccag
ttggcttcacccatgtttggagacaaggacagtctcccaacaaacccagtagagccacca
cactgttcagagtataaaatgcaaatggcagtctccctgcgtcttgccttgcctcccccg
accgagaatagcagcctctcctcaattacccttttagatccaggtgaacactactgctaa

KEGG   Pan paniscus (bonobo): 100974292
Entry
100974292         CDS       T02283                                 

Gene name
CSF3R
Definition
(RefSeq) colony stimulating factor 3 receptor
  KO
K05061  granulocyte colony-stimulating factor receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100974292 (CSF3R)
   04151 PI3K-Akt signaling pathway
    100974292 (CSF3R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100974292 (CSF3R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100974292 (CSF3R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100974292 (CSF3R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100974292 (CSF3R)
   04090 CD molecules [BR:pps04090]
    100974292 (CSF3R)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  Prolactin receptor family
   100974292 (CSF3R)
CD molecules [BR:pps04090]
 Proteins
  100974292 (CSF3R)
SSDB
Motif
Pfam: Lep_receptor_Ig fn3 EpoR_lig-bind IL6Ra-bind fn3_2 ObR_Ig
Other DBs
NCBI-GeneID: 100974292
NCBI-ProteinID: XP_003812645
UniProt: A0A2R9BQ68
Position
1
AA seq 836 aa
MARLGTCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQ
ILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAG
YPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPK
DGQSHCSIPRRHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPE
AAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRAEANWALVGPLPLEALQYELCGLLPA
TAYTLQIRCIRWPLPGHWSDWSPSLELRTTEWAPTVRLDTWWRQRQLDPRTVQLFWKPVP
LEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPT
PVVFSESRGPALTRLHAMARDPHSLWVGWEPPSPWPQGYVIEWGLGPPSASNSNKTWRME
QNGRATGFLLKENIRPFQLYEITVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGK
TWAQLEWVPEPPELGKSPLTHYTIFCTNAQNQSFSAILNASSRGFVLHGLEPASLYHIHL
MAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPNRKNPLWP
SVPDPAHSSLGSWVPTVMEEDAFQLPGLGTPPITKLTVLEEDEKKPVPWESHNSSETCGL
PTLVQTYVLQGDPRAASTQPQSQSGTSDQVLYGQLLGSPTSPGPGHYLRCDSTQPLLAGL
TPSPKSYENLWFQASPLGTLVTPAPSQEDDCVFGPLLNFPLLQGIRVHGMEALGSF
NT seq 2511 nt   +upstreamnt  +downstreamnt
atggcaaggctgggaacctgcagcctgacttgggctgccctgatcatcctgctgctcccc
ggaagtctggaggagtgcgggcacatcagtgtctcagcccccatcgtccacctgggggat
cccatcacagcctcctgcatcatcaagcagaactgcagccatctggacccggagccacag
attctgtggagactgggagcagagcttcagcccgggggcaggcagcagcgtctgtctgat
gggacccaggaatctatcatcaccctgccccacctcaaccacactcaggcctttctctcc
tgctgcctgaactggggcaacagcctgcagatcctggaccaggttgagctgcgcgcaggc
taccctccagccataccccacaacctctcctgcctcatgaacctcacaaccagcagcctc
atctgccagtgggagccaggacctgagacccacctacccaccagcttcactctgaagagc
ttcaagagccggggcaactgtcagacccaaggggactccatcctggactgcgtgcccaag
gacgggcagagccactgctccatcccacgcagacacctgctgttgtaccagaatatgggc
atctgggtgcaggcggagaacgcgctggggaccagcatgtccccacaactgtgccttgat
cccatggacgttgtgaaactggagccccccatgctgcggaccatggaccccagccctgaa
gcagcccctccccaggcaggctgcctacagctgtgctgggagccatggcagccaggcctg
cacataaatcagaagtgtgagctgcgccacaagccgcagcgtgcagaagccaactgggca
ctggtgggccccctccccttggaggcccttcagtatgagctctgcgggctcctcccagcc
acggcctacaccctgcagatacgctgcatccgctggcccctgcctggccactggagcgac
tggagccccagcctggagctgagaactaccgaatgggcccccactgtcagactggacaca
tggtggcggcagaggcagctggaccccaggacagtgcagctgttctggaagccagtgccc
ctggaggaagacagcggacggatccaaggttatgtggtttcttggagaccctcaggccag
gctggggccatcctgcccctctgcaacaccacagagctcagctgcaccttccacctgcct
tcagaagcccaggaggtggcccttgtggcctataactcagccgggacctctcgtcccacc
ccggtggtcttctcagaaagcagaggcccagccctgacaagactccatgccatggcccga
gaccctcacagcctctgggtaggctgggagccccccagtccatggcctcagggctatgtg
attgagtggggcctgggcccccccagcgcgagcaatagcaacaagacctggaggatggaa
cagaatgggagagccacggggtttctgctgaaggagaacatcaggccctttcagctctat
gagatcaccgtgactcccttgtaccaggacaccatgggaccctcccagcatgtctatgcc
tactcccaagaaatggctccctcccatgccccagagctgcatctaaagcacattggcaag
acctgggcacagctggagtgggtgcctgagccccctgagctggggaagagcccccttacc
cactacaccatcttctgtaccaacgctcagaaccagtccttctccgccatcctgaatgcc
tcctcccgtggctttgtcctccatggcctggagcccgccagtctgtatcacatccacctc
atggctgccagccaggctggggccaccaacagtacagtcctcaccctgatgaccttgacc
ccagaggggtcggagctacacatcatcctgggcctgttcggcctcctgctgttgctcacc
tgcctctgtggaactgcctggctctgctgcagccccaacaggaagaatcccctctggcca
agtgtcccagacccagctcacagcagcctgggctcctgggtgcccacagtcatggaggag
gatgccttccagctgcccggccttggcacgccacccatcaccaagctcacagtgctggag
gaggatgagaagaagccggtgccctgggagtcccataacagctcagagacctgtggcctc
cctactctggtccagacctatgtgctccagggggacccaagagcagcttccacccagccc
caatcccagtctggcaccagcgatcaggtcctttatgggcagctgctgggcagccccaca
agcccagggccagggcactatctccgctgtgactccactcagcctctcttggcgggcctc
acccccagccccaagtcctatgagaacctctggttccaggccagccccttggggaccctg
gtaaccccagccccaagccaggaggacgactgtgtctttgggccactgctcaacttcccc
ctcctgcaggggatccgggtccatgggatggaggcgctggggagcttctag

KEGG   Pan paniscus (bonobo): 100974295
Entry
100974295         CDS       T02283                                 

Gene name
CNTFR
Definition
(RefSeq) ciliary neurotrophic factor receptor
  KO
K05059  ciliary neurotrophic factor receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100974295 (CNTFR)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100974295 (CNTFR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100974295 (CNTFR)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:pps00537]
    100974295 (CNTFR)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100974295 (CNTFR)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:pps00537]
 Receptors
  100974295 (CNTFR)
SSDB
Motif
Pfam: fn3 Ig_3 Ig_5 MAGI_u5
Other DBs
NCBI-GeneID: 100974295
NCBI-ProteinID: XP_003829850
UniProt: A0A2R9C7G4
Position
9
AA seq 372 aa
MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVN
GTDLAPDLLNGSQLVLRGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNT
YPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVS
ISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPL
KFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHAT
PWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLAL
AAAAATASSLLI
NT seq 1119 nt   +upstreamnt  +downstreamnt
atggctgctcctgtcccatgggcctgctgtgctgtgcttgctgccgccgccgcagttgtc
tacgcccagagacacagtccacaggaggcaccccatgtgcagtacgagcgcctgggctct
gacgtgacactgccatgtgggacagcaaactgggatgctgcggtgacgtggagggtaaat
gggacagacctggcccctgacctgctcaacggctctcagctggtgctccgtggcctggaa
ctgggccacagtggtctctacgcctgcttccaccgtgactcctggcacctgcgccaccaa
gtcctgctgcatgtgggcttgccaccgcgggagcctgtgctcagctgccgctccaacact
taccccaagggcttctactgcagctggcatctgcccacccccacctacattcccaacacc
ttcaatgtgactgtgctgcatggctccaaaattatggtctgtgagaaggacccagccctc
aagaaccgctgccacattcgctacatgcacctgttctccaccatcaagtacaaggtctcc
ataagtgtcagcaatgccctgggccacaatgccacagctatcacctttgacgagttcacc
attgtgaagcctgatcctccagaaaatgtggtagcccggccagtgcccagcaaccctcgc
cggctggaggtgacgtggcagaccccctcgacctggcctgaccctgagtcttttcctctc
aagttctttctgcgctaccgacccctcatcctggaccagtggcagcatgtggagctgtcc
gacggcacagcacacaccatcacagatgcctacgccgggaaggagtacattatccaggtg
gcagccaaggacaatgagatcgggacatggagtgactggagcgtggctgcccacgctacg
ccctggactgaggaaccgcgacacctcaccacggaggcccaggctgcggagaccacgacc
agcaccaccagctccctggcacccccacctaccacgaagatctgtgaccctggggagctg
ggcagcggcgggggaccctcggcacccttcttggtcagcgtccccatcactctggccctg
gctgccgctgccgccactgccagcagtctcttgatctga

KEGG   Pan paniscus (bonobo): 100974407
Entry
100974407         CDS       T02283                                 

Gene name
IL2RA
Definition
(RefSeq) interleukin 2 receptor subunit alpha
  KO
K05068  interleukin 2 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04144  Endocytosis
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps05162  Measles
pps05166  Human T-cell leukemia virus 1 infection
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100974407 (IL2RA)
   04151 PI3K-Akt signaling pathway
    100974407 (IL2RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100974407 (IL2RA)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100974407 (IL2RA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100974407 (IL2RA)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100974407 (IL2RA)
   04658 Th1 and Th2 cell differentiation
    100974407 (IL2RA)
   04659 Th17 cell differentiation
    100974407 (IL2RA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100974407 (IL2RA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100974407 (IL2RA)
   05162 Measles
    100974407 (IL2RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100974407 (IL2RA)
   04090 CD molecules [BR:pps04090]
    100974407 (IL2RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100974407 (IL2RA)
CD molecules [BR:pps04090]
 Proteins
  100974407 (IL2RA)
SSDB
Motif
Pfam: Sushi TMEM100
Other DBs
NCBI-GeneID: 100974407
NCBI-ProteinID: XP_014201833
Position
10
AA seq 208 aa
MDSYLLMWGLLTLIMVPGCQAATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGH
CREPPPWENEATERIYHFVVGQTVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLIC
TGEMETSQFPGEEKPQASPEGRPESETSCLITTTDFQIQTEMAATMETFIFTTEYQVAVA
GCVFLLISVLLLSGLTWQRRQRKSRRTI
NT seq 627 nt   +upstreamnt  +downstreamnt
atggattcatacctgctgatgtggggactgctcacgctcatcatggtgcctggctgccag
gcagccactcggaacacaacgaaacaagtgacacctcaacctgaagaacagaaagaaagg
aaaaccacagaaatgcaaagtccaatgcagccagtggaccaagcgagccttccaggtcac
tgcagggaacctccaccgtgggaaaatgaagccacagagagaatttatcatttcgtggtg
gggcagacggtttactaccagtgcgtccagggatacagggctctacacagaggtcctgct
gagagcgtctgcaaaatgacccatgggaagacaaggtggacccagccccagctcatatgc
acaggtgaaatggagaccagtcagtttccaggtgaagagaagcctcaggcaagccccgaa
ggccgtcctgagagtgagacttcctgcctcatcacaacaacagattttcaaatacagaca
gaaatggctgcaaccatggagacgttcatatttacaacagagtaccaggtagcagtggcc
ggctgtgttttcctgctgatcagcgtcctcctcctgagtgggctcacctggcagcggaga
cagaggaagagtagaagaacaatctag

KEGG   Pan paniscus (bonobo): 100974885
Entry
100974885         CDS       T02283                                 

Gene name
EGFR
Definition
(RefSeq) epidermal growth factor receptor
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps01522  Endocrine resistance
pps04010  MAPK signaling pathway
pps04012  ErbB signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04066  HIF-1 signaling pathway
pps04068  FoxO signaling pathway
pps04072  Phospholipase D signaling pathway
pps04144  Endocytosis
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04520  Adherens junction
pps04540  Gap junction
pps04630  JAK-STAT signaling pathway
pps04810  Regulation of actin cytoskeleton
pps04912  GnRH signaling pathway
pps04915  Estrogen signaling pathway
pps04921  Oxytocin signaling pathway
pps04926  Relaxin signaling pathway
pps04928  Parathyroid hormone synthesis, secretion and action
pps04934  Cushing syndrome
pps05160  Hepatitis C
pps05163  Human cytomegalovirus infection
pps05165  Human papillomavirus infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05205  Proteoglycans in cancer
pps05206  MicroRNAs in cancer
pps05210  Colorectal cancer
pps05212  Pancreatic cancer
pps05213  Endometrial cancer
pps05214  Glioma
pps05215  Prostate cancer
pps05218  Melanoma
pps05219  Bladder cancer
pps05223  Non-small cell lung cancer
pps05224  Breast cancer
pps05225  Hepatocellular carcinoma
pps05226  Gastric cancer
pps05230  Central carbon metabolism in cancer
pps05231  Choline metabolism in cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100974885 (EGFR)
   04012 ErbB signaling pathway
    100974885 (EGFR)
   04014 Ras signaling pathway
    100974885 (EGFR)
   04015 Rap1 signaling pathway
    100974885 (EGFR)
   04630 JAK-STAT signaling pathway
    100974885 (EGFR)
   04066 HIF-1 signaling pathway
    100974885 (EGFR)
   04068 FoxO signaling pathway
    100974885 (EGFR)
   04020 Calcium signaling pathway
    100974885 (EGFR)
   04072 Phospholipase D signaling pathway
    100974885 (EGFR)
   04151 PI3K-Akt signaling pathway
    100974885 (EGFR)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100974885 (EGFR)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100974885 (EGFR)
   04520 Adherens junction
    100974885 (EGFR)
   04540 Gap junction
    100974885 (EGFR)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100974885 (EGFR)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    100974885 (EGFR)
   04915 Estrogen signaling pathway
    100974885 (EGFR)
   04921 Oxytocin signaling pathway
    100974885 (EGFR)
   04926 Relaxin signaling pathway
    100974885 (EGFR)
   04928 Parathyroid hormone synthesis, secretion and action
    100974885 (EGFR)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100974885 (EGFR)
   05206 MicroRNAs in cancer
    100974885 (EGFR)
   05205 Proteoglycans in cancer
    100974885 (EGFR)
   05230 Central carbon metabolism in cancer
    100974885 (EGFR)
   05231 Choline metabolism in cancer
    100974885 (EGFR)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100974885 (EGFR)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100974885 (EGFR)
   05212 Pancreatic cancer
    100974885 (EGFR)
   05225 Hepatocellular carcinoma
    100974885 (EGFR)
   05226 Gastric cancer
    100974885 (EGFR)
   05214 Glioma
    100974885 (EGFR)
   05218 Melanoma
    100974885 (EGFR)
   05219 Bladder cancer
    100974885 (EGFR)
   05215 Prostate cancer
    100974885 (EGFR)
   05213 Endometrial cancer
    100974885 (EGFR)
   05224 Breast cancer
    100974885 (EGFR)
   05223 Non-small cell lung cancer
    100974885 (EGFR)
  09172 Infectious disease: viral
   05160 Hepatitis C
    100974885 (EGFR)
   05171 Coronavirus disease - COVID-19
    100974885 (EGFR)
   05163 Human cytomegalovirus infection
    100974885 (EGFR)
   05165 Human papillomavirus infection
    100974885 (EGFR)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100974885 (EGFR)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100974885 (EGFR)
   01522 Endocrine resistance
    100974885 (EGFR)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100974885 (EGFR)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pps04147]
    100974885 (EGFR)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100974885 (EGFR)
Protein kinases [BR:pps01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   100974885 (EGFR)
Exosome [BR:pps04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   100974885 (EGFR)
  Exosomal proteins of pancreatic cancer cells
   100974885 (EGFR)
  Exosomal proteins of bladder cancer cells
   100974885 (EGFR)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like Kinase-like APH GAPT ABC1 Kdo
Other DBs
NCBI-GeneID: 100974885
NCBI-ProteinID: XP_008967087
UniProt: A0A2R9CMH6
Position
7
AA seq 1157 aa
MFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYY
ENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFL
SNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCH
NQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVK
KCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINA
TNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPEN
RTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN
TINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGR
ECVDKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCIK
TCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGA
LLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFK
KIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPH
VCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRL
VHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTH
QSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMI
DADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDA
DEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTMACIDRNGLQSCPIKEDSFLQRYSSDP
TGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPTPSRDPHYQDPHSTAV
GNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAE
NAEYLRVAPQSSEFIGA
NT seq 3474 nt   +upstreamnt  +downstreamnt
atgttcaataactgtgaggtggtccttgggaatttggaaattacctatgtgcagaggaat
tatgatctttccttcttaaagaccatccaggaggtggctggttatgtcctcattgccctc
aacacagtggagcggattcctttggaaaacctgcagatcatcagaggaaatatgtactat
gaaaattcctacgccttagcagtcttatctaactatgatgcaaataaaaccggactgaag
gagctgcccatgagaaatttacaggaaatcctgcatggcgccgtgcggttcagcaacaac
cctgccctgtgcaacgtggaaagcatccagtggcgggacatagtcagcagtgactttctc
agcaacatgtcaatggacttccagaaccacctgggcagctgccaaaagtgtgatccaagc
tgtcccaatgggagctgctggggtgcaggagaggagaactgccagaaactgaccaaaatc
atctgtgcccagcagtgctccgggcgctgccgcggcaagtcccccagtgactgctgccac
aaccagtgtgccgcaggctgcacgggcccccgggagagcgactgcctggtgtgccgcaaa
ttccgagatgaagccacgtgcaaggacacctgccccccactcatgctctacaaccccacc
acgtaccagatggatgtgaaccccgagggcaaatacagctttggtgccacctgcgtgaag
aagtgtccccgtaattatgtggtgacagatcacggctcgtgcgtccgagcctgtggggcc
gacagctatgagatggaggaagacggcgtccgcaagtgtaagaagtgcgaagggccttgc
cgcaaagtgtgtaacggaataggtattggtgaatttaaagacacactctccataaatgct
acgaatattaaacacttcaaaaactgcacctccatcagtggcgatctccacatcctgccg
gtggcatttaggggtgactccttcacacatactccgcctctggatccacaggaactggat
attctgaaaaccgtaaaggaaatcacagggtttttgctgattcaggcttggcctgaaaac
aggacggacctccatgcttttgagaacctagaaatcatacgcggcaggaccaagcaacat
ggtcagttttctcttgcggttgtcagcctgaacataacatccttgggattacgctccctc
aaggagataagtgatggagatgtgataatttcaggaaacaaaaatttgtgctatgcaaat
acaataaactggaaaaaactgtttgggacctccggtcagaaaacgaaaattataagcaac
agaggtgaaaacagctgcaaggccacaggccaggtctgccatgccttgtgctcccccgag
ggctgctggggcccggagcccagggactgcgtctcttgccggaatgtcagccgaggcagg
gaatgcgtggacaagtgcaacattctggagggcgagccaagggagtttgtggagaactct
gagtgcatacagtgccacccagagtgcctgcctcaggccatgaacatcacctgcacagga
cggggaccagacaactgtatccagtgtgcccactacattgacggcccccactgcatcaag
acctgcccggcaggagtcatgggagaaaacaacaccctggtctggaagtacgcagatgcc
ggccatgtgtgccacctgtgccatccaaactgcacctacggatgcactgggccaggtctt
gaaggctgtccaacgaatgggcctaagatcccttccatcgccactgggatggtgggggcc
ctcctcttgctgctggtggtggccctggggatcggcctcttcatgcgaaggcgccacatc
gttcggaagcgcacgctgcggaggctgctgcaggagagggagcttgtggagcctcttaca
cccagtggagaagctcccaaccaagctctcttgaggatcttgaaggaaactgaattcaaa
aagatcaaagtgctggggtccggtgcgttcggcacggtgtataagggactctggatccca
gaaggtgagaaagttaaaattcccgtcgctatcaaggaattaagagaagcaacgtctccg
aaagccaacaaggaaatcctcgatgaagcctacgtgatggccagcgtggacaacccccac
gtgtgccgcctgctgggcatctgcctcacctccaccgtgcagctcatcacgcagctcatg
cccttcggctgcctcctggactatgtccgggaacacaaagacaatattggctcccagtac
ctgctcaactggtgtgtgcagatcgcaaagggcatgaactacttggaggaccgtcgcttg
gtgcaccgcgacctggcagccaggaacgtactggtgaaaacaccgcagcatgtcaagatc
acagattttgggctggccaaactgctgggtgcagaagagaaagaatatcatgcagaagga
ggcaaagtgcctatcaagtggatggcattggaatcaattttacacagaatctatacccac
cagagtgatgtctggagctacggggtgaccgtttgggagttgatgacctttggatccaag
ccatatgacggaatccctgccagcgagatctcctccatcctggagaaaggagaacgcctc
cctcagccacccatatgtaccatcgatgtctacatgatcatggtcaagtgctggatgata
gacgcagatagtcgcccaaagttccgtgagttgatcatcgaattctccaaaatggcccga
gacccccagcgctaccttgtcattcagggggatgaaagaatgcatttgccaagccctaca
gattccaacttctaccgtgccctgatggatgaagaagacatggacgacgtggtggatgcc
gacgagtacctcatcccacagcagggcttcttcagcagcccctccacgtcacggactccc
ctcctgagctctctgagtgcaaccagcaacaattccactatggcttgcattgatagaaat
gggctgcaaagctgtcccatcaaggaagacagcttcttgcagcgatacagctcagacccc
acaggcgccttgactgaggacagcatagacgacaccttcctcccagtgcctgaatacata
aaccagtccgttcccaaaaggcccgctggctctgtgcagaatcctgtctatcacaatcag
cctctgaaccccacgcccagcagagacccacactaccaggacccccacagcactgcagtg
ggcaaccccgagtatctcaacactgtccagcccacctgtgtcaacagcacattcgacagc
cctgcccactgggcccagaaaggcagccaccaaattagcctggacaaccctgactaccag
caggacttctttcccaaggaagccaagccaaatggcatctttaagggctccacagctgaa
aatgcagaatacctaagggtagcgccacaaagcagtgaatttattggagcatga

KEGG   Pan paniscus (bonobo): 100975260
Entry
100975260         CDS       T02283                                 

Gene name
LEPR
Definition
(RefSeq) leptin receptor
  KO
K05062  leptin receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04080  Neuroactive ligand-receptor interaction
pps04152  AMPK signaling pathway
pps04630  JAK-STAT signaling pathway
pps04920  Adipocytokine signaling pathway
pps04932  Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100975260 (LEPR)
   04152 AMPK signaling pathway
    100975260 (LEPR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100975260 (LEPR)
   04060 Cytokine-cytokine receptor interaction
    100975260 (LEPR)
 09150 Organismal Systems
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100975260 (LEPR)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100975260 (LEPR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100975260 (LEPR)
   04090 CD molecules [BR:pps04090]
    100975260 (LEPR)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  Prolactin receptor family
   100975260 (LEPR)
CD molecules [BR:pps04090]
 Proteins
  100975260 (LEPR)
SSDB
Motif
Pfam: ObR_Ig Lep_receptor_Ig fn3
Other DBs
NCBI-GeneID: 100975260
NCBI-ProteinID: XP_008957199
UniProt: A0A2R9B1D1
Position
1
AA seq 1165 aa
MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNS
NGRYETAVEPKFNSSGTLFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVF
QQIDANWNIQCWLKGDLKLFICYVESLFKNPFRNYNYKVHLLYVLPEVLEDSPLVPQKGS
FQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPP
LGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILP
GSSYEVQVRGKRLDGPGIWSDWSTPHVFTTQDVIYFPPKILTSVGSNVAFHCIYKNENKI
VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHH
RYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIH
PISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPP
SSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPV
PDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNV
TLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSI
GASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNED
GEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDA
GLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFI
KHTASVTCGPLLLEPETISEDISVDTSWKNKDEMVPTTVVSLLSTTDLEKGSVCISDQFN
SVNFSEAEGTEVTYEDESQIQPFVKYATLISNSKPNETGEEQGLINSSVTKCFSSKNSPL
KDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDEKSIYYL
GVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNFNLGTSSKKTFAS
YMPQFQTCSTQTHKIMENKMCDLTV
NT seq 3498 nt   +upstreamnt  +downstreamnt
atgatttgtcaaaaattctgtgtcgttttgttacattgggaatttatttatgtgataact
gcatttaacttgtcatatccaattactccttggagatttaagttgtcttgcatgccacca
aattcaacctatgactacttccttttgcctgctggactctcaaagaatacttcaaattcg
aatggacgttatgagacagctgttgaacctaagtttaattcaagtggtactctcttttct
aacttatccaaaacaactttccactgttgctttcggagtgagcaagatagaaactgctcc
ttatgtgcagacaacattgaaggaaagacatttgtttcaacagtaaattctttagttttt
caacaaatagatgcaaactggaacatacagtgctggctaaaaggagacttaaaattattc
atctgttatgtggagtcattatttaagaatccattcaggaattataactataaggtccat
cttttatatgttctgcctgaagtgttagaagattcgcctctggttccccaaaaaggcagt
tttcagatggttcactgcaattgcagtgttcatgaatgttgtgaatgtcttgtgcctgtg
ccaacagccaaactcaacgacactctccttatgtgtttgaaaatcacatctggtggagta
attttccagtcacctctaatgtcagttcagcccataaatatggtgaagcctgatccacca
ttaggtttgcatatggaaatcacagatgatggtaatttaaagatttcttggtccagccca
ccattggtaccatttccacttcaatatcaagtgaaatattcagagaattctacaacagtt
atcagagaagctgacaagattgtctcagctacatccctgctggtagacagtatacttcct
gggtcttcgtatgaggttcaggtgaggggcaagagactggatggcccaggaatctggagt
gactggagtactcctcatgtctttaccacacaagatgtaatatactttccacctaaaatt
ctgacaagtgttgggtctaatgttgcttttcactgcatctataagaatgaaaacaagatt
gttccctcaaaagagattgtttggtggatgaatttagctgagaaaattcctcaaagccag
tatgatgttgtgagtgatcatgttagcaaagttacttttttcaatctgaatgaaaccaaa
cctcgaggaaagtttacctatgatgcagtgtactgctgcaatgaacatgaatgccatcat
cgctatgctgaattatatgtgattgatgtcaatatcaatatctcatgtgaaactgatggg
tacttaactaaaatgacttgcagatggtcaaccagtacaatccagtcacttgcggaaagc
actttgcaattgaggtatcataggagcagcctttactgttctgatattccatctattcat
cccatatctgagcccaaagattgctatttgcagagtgatggtttttatgaatgcattttc
cagccaatcttcctattatctggctacacaatgtggattaggatcaatcactctctaggt
tcacttgactctccaccaacatgtgtccttcctgattctgtggtgaagccactgcctcca
tccagtgtgaaagcagaaattactataaacattggattattgaaaatatcttgggaaaag
ccagtctttccagagaataaccttcaattccagattcgctatggtttaagtggaaaagaa
gtacaatggaagatgtatgaggtttatgatgcaaaatcaaaatctgtcagtctcccagtt
ccagacttgtgtgcagtctatgctgttcaggtgcgctgtaagaggctagatggactggga
tattggagtaattggagcaatccagcctacacagttgtcatggatataaaagttcctatg
agaggacctgaattttggagaataattaatggagatactatgaaaaaggagaaaaatgtc
actttactttggaagcccctgatgaaaaatgactcattgtgcagtgttcagagatatgtg
ataaaccatcatacttcctgcaatggaacatggtcagaagatgtgggaaatcacacgaaa
ttcactttcctgtggacagagcaagcacatactgttacggttctggccatcaattcaatt
ggtgcttctgttgcaaattttaatttaaccttttcatggcctatgagcaaagtaaatatc
gtgcagtcactcagtgcttatcctttaaacagcagttgtgtgattgtttcctggatacta
tcacccagtgattacaagctaatgtattttattattgagtggaaaaatcttaatgaagat
ggtgaaataaaatggcttagaatctcttcatctgttaagaagtattatattcatgatcat
tttatccccattgagaagtaccagttcagtctttacccaatatttatggaaggagtggga
aaaccaaagataattaatagtttcactcaagatgatattgaaaaacaccagagtgatgca
ggtttatatgtaattgtgccagtaattatttcctcttccatcttattgcttggaacatta
ttaatatcacaccaaagaatgaaaaagctgttttgggaagatgttccgaaccctaagaat
tgttcctgggcacaaggacttaattttcagaagccagaaacgtttgagcatctttttatc
aagcatacagcatcagtgacatgtggtcctcttcttttggagcctgaaacaatttcagaa
gatatcagtgttgatacatcatggaaaaataaagatgagatggtgccaacaactgtggtc
tctctactttcaacaacagatcttgaaaagggttctgtttgtattagtgaccagttcaac
agtgttaacttctctgaggctgagggtaccgaggtaacctatgaggacgaaagccagata
caaccctttgttaaatatgccacgctgatcagcaactctaaaccaaatgaaactggtgaa
gaacaagggcttataaatagttcagtcaccaagtgcttctctagcaaaaattctccattg
aaggattctttctctaatagctcatgggagatagaggcccaggcattttttatattatca
gatcagcatcccaacataatttcaccacacctcacattctcagaaggattggatgaactt
ttgaaattggaggggaatttccctgaagaaaataatgatgagaagtctatctattattta
ggggtcacctcaatcaaaaagagagagagtggtgtgcttttgactgacaagtcaagggta
tcgtgcccattcccagccccctgtttattcacggacatcagagttctccaagacagttgc
tcacactttgtagaaaataatttcaacttaggaacttctagtaagaagacttttgcatct
tacatgcctcaattccaaacttgttctactcagactcataagatcatggaaaacaagatg
tgtgacctaactgtgtaa

KEGG   Pan paniscus (bonobo): 100975853
Entry
100975853         CDS       T02283                                 

Gene name
PDGFRB
Definition
(RefSeq) platelet derived growth factor receptor beta
  KO
K05089  platelet-derived growth factor receptor beta [EC:2.7.10.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04072  Phospholipase D signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04540  Gap junction
pps04630  JAK-STAT signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05165  Human papillomavirus infection
pps05200  Pathways in cancer
pps05206  MicroRNAs in cancer
pps05214  Glioma
pps05215  Prostate cancer
pps05218  Melanoma
pps05230  Central carbon metabolism in cancer
pps05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100975853 (PDGFRB)
   04014 Ras signaling pathway
    100975853 (PDGFRB)
   04015 Rap1 signaling pathway
    100975853 (PDGFRB)
   04630 JAK-STAT signaling pathway
    100975853 (PDGFRB)
   04020 Calcium signaling pathway
    100975853 (PDGFRB)
   04072 Phospholipase D signaling pathway
    100975853 (PDGFRB)
   04151 PI3K-Akt signaling pathway
    100975853 (PDGFRB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100975853 (PDGFRB)
   04540 Gap junction
    100975853 (PDGFRB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100975853 (PDGFRB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100975853 (PDGFRB)
   05206 MicroRNAs in cancer
    100975853 (PDGFRB)
   05230 Central carbon metabolism in cancer
    100975853 (PDGFRB)
   05231 Choline metabolism in cancer
    100975853 (PDGFRB)
  09162 Cancer: specific types
   05214 Glioma
    100975853 (PDGFRB)
   05218 Melanoma
    100975853 (PDGFRB)
   05215 Prostate cancer
    100975853 (PDGFRB)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100975853 (PDGFRB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100975853 (PDGFRB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100975853 (PDGFRB)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:pps04090]
    100975853 (PDGFRB)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100975853 (PDGFRB)
Protein kinases [BR:pps01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   100975853 (PDGFRB)
CD molecules [BR:pps04090]
 Proteins
  100975853 (PDGFRB)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 V-set TrmE_N TCAD9 Haspin_kinase
Other DBs
NCBI-GeneID: 100975853
NCBI-ProteinID: XP_008952698
Position
5
AA seq 1119 aa
MDTMRLLGAMPALALKGKLLLLPLLLLLEPQISQGLVVTPPGPELVLNVSSTFVLTCSGS
APVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLY
IFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQR
GFSGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIV
IGNEVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAXXXXXXXPSAELEDSG
TYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPT
VLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQL
SFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLG
NSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHS
LPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQL
PYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQA
LMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDK
RRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIE
SSNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDL
AARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVW
SFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEI
RPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSV
LYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQ
DEPEPEPQLELQVEPEPELEQLPDSGCPAPRAEAEDSFL
NT seq 3360 nt   +upstreamnt  +downstreamnt
atggacaccatgcggcttctgggtgcgatgccagctctggccctcaaaggcaagctgctg
ttgctgcccctcctgttactgctggaaccacagatctctcagggcctggtcgtcacaccc
ccggggccagagcttgtcctcaatgtctccagcaccttcgttctgacctgctcgggttca
gctccggtggtgtgggaacggatgtcccaggagcccccacaggaaatggccaaggcccag
gacggcaccttctccagcgtgctcacactgaccaacctcactgggctagacacgggagaa
tacttttgcacccacaatgactcccgtggactggagaccgatgagcggaaacggctctac
atctttgtgccagatcccaccgtgggcttcctccctaatgatgccgaggaactattcatc
tttctcacggaaataactgagatcaccattccatgccgagtaacagacccacagctggtg
gtgacactgcacgagaagaaaggggacgttgcactgcctgtcccctatgatcaccaacgt
ggcttttctggtatctttgaggacagaagctacatctgcaaaaccaccattggggacagg
gaggtggattccgatgcctactatgtctacagactccaggtgtcatccatcaacgtctct
gtgaacgcagtgcagactgtggtccgccagggtgagaacatcaccctcatgtgcattgtg
atcgggaatgaggtggtcaacttcgagtggacatacccccgcaaagaaagtgggcggctg
gtggagccggtgactgacttcctcttggatatgccttaccacatccgctccatcctgcac
atccccagtgcnnnnnnnnnnnnnnnnnnnntccccagtgccgagttagaagactcgggg
acctacacctgcaacgtgacggagagtgtgaatgaccatcaggatgaaaaggccatcaac
atcaccgtggttgagagcggctacgtgcggctcctgggagaggtgggcacactacagttt
gctgagctgcatcggagccggacactgcaggtagtgttcgaggcctacccaccgcccact
gtcctgtggttcaaagacaaccgcaccctgggcgactccagcgctggcgaaatcgccctg
tccacgcgcaacgtgtcggagacccggtatgtgtcagagctgacactggttcgcgtgaag
gtggcagaggctggccactacaccatgcgggccttccatgaggatgctgaggtccagctc
tccttccagctacagatcaatgtccctgtccgagtgctggagctaagtgagagccaccct
gacagtggggaacagacagtccgctgtcgtggccggggcatgccccagccgaacatcatc
tggtctgcctgcagagacctcaaaaggtgtccacgcgagctgccgcccacgctgctgggg
aacagttccgaagaggagagccagctggagactaacgtgacgtactgggaggaggagcag
gagtttgaggtggtgagcacactgcgtctgcagcacgtggatcggccgctgtcggtgcgc
tgcacgctgcgcaacgctgtgggccaggacacgcaggaggtcatcgtggtgccacactcc
ttgccctttaaggtggtggtgatctcagccatcctggccctggtggtgctcaccatcatc
tcccttatcatcctcatcatgctttggcagaagaagccacgttacgagatccgatggaag
gtgattgagtctgtgagctctgacggccatgagtacatctacgtggaccccatgcagctg
ccctatgactccacgtgggagctgccgcgggaccagcttgtgctgggacgcaccctcggc
tctggggcctttgggcaggtggtggaggccacggctcatggcctgagccattctcaggcc
acgatgaaagtggccgtcaagatgcttaaatccacagcccgcagcagtgagaagcaagcc
cttatgtcggagctgaagatcatgagtcaccttgggccccacctgaacgtggtcaacctg
ttgggggcctgcaccaaaggaggacccatctatatcatcactgagtactgccgctacgga
gacctggtggactacctgcaccgcaacaaacataccttcctgcagcaccactccgacaag
cgccgcccgcccagcgcggagctctacagcaatgcactgcccgttgggctccccctgccc
agccatgtgtccttgaccggggagagcgacggtggctacatggacatgagcaaggacgag
tcggtggactatgtgcccatgctggacatgaaaggagacgtcaaatatgcagacatcgag
tcctccaactacatggccccttatgataactacgttccctctgcccctgagaggacctgc
cgggcaactttgatcaacgagtctccagtgctaagctacatggacctcgtgggcttcagc
taccaggtggccaatggcatggagtttctggcctccaagaactgcgtccacagagacctg
gcggctaggaacgtgctcatctgtgaaggcaagctggtcaagatctgtgactttggcctg
gctcgagacatcatgcgggactcgaattacatctccaaaggcagtacctttttgcctttg
aagtggatggctccggagagcatcttcaacagcctctacaccaccctgagtgacgtgtgg
tcctttgggatcctgctctgggagatcttcaccttgggtggcaccccttacccagagctg
cccatgaatgagcagttctacaatgccatcaaacggggttaccgcatggcccagcctgcc
catgcctccgacgagatctatgagatcatgcagaagtgctgggaagagaagtttgagatt
cggccccccttctcccagctggtgctgcttctcgagagactgttgggcgaaggttacaaa
aagaagtaccagcaggtggatgaggagtttctgaggagtgaccacccagccatccttcgg
tcccaggcccgcttgcctgggttccatggcctccgatctcccctggacaccagctccgtc
ctctatactgccgtgcagcccaatgagggtgacaacgactatatcatccccctgcctgac
cccaaacccgaggttgctgacgagggcccactggagggttcccccagcctagccagctcc
accctgaatgaagtcaacacctcctcaaccatctcctgtgacagcccgctggagccccag
gacgaaccagagccagagccccagcttgagctccaggtggagccggagccagagctggaa
cagttgccggattcggggtgccctgcgcctcgggcggaagcagaggatagcttcctgtag

KEGG   Pan paniscus (bonobo): 100976877
Entry
100976877         CDS       T02283                                 

Gene name
IL11RA
Definition
(RefSeq) interleukin 11 receptor subunit alpha
  KO
K05056  interleukin 11 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100976877 (IL11RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100976877 (IL11RA)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100976877 (IL11RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100976877 (IL11RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100976877 (IL11RA)
SSDB
Motif
Pfam: Ig_3 ig Ig_2 EpoR_lig-bind I-set
Other DBs
NCBI-GeneID: 100976877
NCBI-ProteinID: XP_008953451
Position
9
AA seq 473 aa
MGQEPPYFTPLLPLAPGRSRPRCGGPGREGVEAGAEGEGEGRGRWRQRPRKMSSSCSGLS
RVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQ
GPDSGLGHELVLAQADSTDEGTYICRTLDGALGGTVTLQLGYPPARPVVSCQAADYENFS
CTWSPSQISGLPTRYLTSYRKKTVLGDDSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWS
QYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPRQ
PHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWSA
EAWGTPSTGTVPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHRDSVEQVAVL
ASLGILSFLGLVAGALALGLWLRLRQGGKDGSPKTGFLASVIPVDRRPGAPNL
NT seq 1422 nt   +upstreamnt  +downstreamnt
atgggccaggagcccccctatttcactcctctccttccattggcgcctgggcggagccgc
ccccgctgcgggggcccagggcgggagggagtagaggccggggcagagggcgagggcgag
ggcagagggcgctggcggcagcggccgcggaagatgagcagcagctgctcagggctgagc
agggtcctggtggccgtggctacagccctggtgtctgcctcctccccctgcccccaggcc
tggggccccccaggggtccagtatgggcagccaggcaggtccgtgaagctgtgttgtcct
ggagtgactgccggggacccagtgtcctggtttcgggatggggagccaaagctgctccag
ggacctgactctgggctagggcatgaactggtcctggcccaggcagacagcactgatgag
ggcacctacatctgccggaccctggatggtgcacttgggggcacagtgaccctgcagctg
ggctaccctccagcccgccctgttgtctcctgccaagcagccgactatgagaacttctct
tgcacttggagtcccagccagatcagcggtttacccacccgctacctcacctcctacagg
aagaagacagtcctaggagatgatagccagaggaggagtccatccacagggccctggcca
tgcccacaggatcccctaggggctgcccgctgtgttgtccacggggctgagttctggagc
cagtaccggattaatgtgactgaggtgaacccactgggtgccagcacacgcctgctggat
gtgagcttgcagagcatcttgcgccctgacccaccccagggcctgcgggtagagtcagta
ccaggttacccccgacgcctgcgagccagctggacataccctgcctcctggccgcgccag
ccccacttcctgctcaagttccgtttgcagtaccgtccggcgcagcatccagcctggtcc
acggtggagccagctggactggaggaggtgatcacagatgctgtggctgggctgccccat
gctgtacgagtcagtgcccgggactttctagatgctggcacctggagcacctggagcgcg
gaggcctggggaactccgagcactgggaccgtaccaaaggagataccagcttggggccag
ctacacacgcagccagaggtggagcctcaggtggacagccctgctcctccaaggccctcc
ctccaaccacaccctcggctacttgatcacagggactctgtggagcaggtagctgtgctg
gcgtctttgggaatcctttctttcctgggactggtggctggggccctggcactggggctc
tggctgaggctgagacagggtgggaaggatggatccccaaagactgggttcttggcctca
gtgattccagtggacaggcgtccaggagctccaaacctgtag

KEGG   Pan paniscus (bonobo): 100977044
Entry
100977044         CDS       T02283                                 

Gene name
IL20RB
Definition
(RefSeq) interleukin 20 receptor subunit beta
  KO
K05137  interleukin 20 receptor beta
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100977044 (IL20RB)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100977044 (IL20RB)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100977044 (IL20RB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100977044 (IL20RB)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL10/28 receptor family
   100977044 (IL20RB)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind
Other DBs
NCBI-GeneID: 100977044
NCBI-ProteinID: XP_008974311
Position
3
AA seq 264 aa
MKHLLMWSPVIAPGETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEGPECDVTDDIMATV
PYNLRVRATLGSQTSAWSILKHPFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLV
AYWRREPGAEEHVKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQ
GEAIPLVLALFAFVGFMLILVVVPLFVWKMGRLLQYSCCPVVVLPDTLKITNSPQKLISC
RREEVDACATAVMSPEELLRAWIS
NT seq 795 nt   +upstreamnt  +downstreamnt
atgaagcatctcttgatgtggagcccagtgatcgcacctggagaaacagtgtactattct
gtcgaataccagggggagtacgagagcctgtacacgagccacatctggatccccagcagc
tggtgctcactcactgaaggtcctgagtgtgatgtcactgatgacatcatggccactgtg
ccatacaaccttcgtgtcagggccacattgggctcacagacctcagcctggagcatcctg
aagcatccctttaatagaaactcaaccatccttacccgacctgggatggagatcaccaaa
gatggcttccacctggttattgagctggaggacctggggccccagtttgagttccttgtg
gcctactggaggagggagcctggtgccgaggaacatgtcaaaatggtgaggagtgggggt
attccagtgcacctggaaaccatggagccaggggctgcatactgtgtgaaggcccagaca
ttcgtgaaggccattgggaggtacagcgccttcagccagacagaatgtgtggaggtgcaa
ggagaggccattcccctggtactggccctgtttgcctttgttggcttcatgctgatcctt
gtggtcgtgccactgttcgtctggaaaatgggccggctgctccagtactcctgttgcccc
gtggtggtcctcccagacaccttgaaaataaccaattcaccccagaagttaatcagctgc
agaagggaggaggtggatgcctgtgccacggctgtgatgtctcctgaggaactcctcagg
gcctggatctcatag

KEGG   Pan paniscus (bonobo): 100979712
Entry
100979712         CDS       T02283                                 

Gene name
IL12RB1
Definition
(RefSeq) interleukin 12 receptor subunit beta 1
  KO
K05063  interleukin 12 receptor beta-1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps05200  Pathways in cancer
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100979712 (IL12RB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100979712 (IL12RB1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100979712 (IL12RB1)
   04659 Th17 cell differentiation
    100979712 (IL12RB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100979712 (IL12RB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100979712 (IL12RB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100979712 (IL12RB1)
   04090 CD molecules [BR:pps04090]
    100979712 (IL12RB1)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100979712 (IL12RB1)
CD molecules [BR:pps04090]
 Proteins
  100979712 (IL12RB1)
SSDB
Motif
Pfam: fn3 Pur_ac_phosph_N
Other DBs
NCBI-GeneID: 100979712
NCBI-ProteinID: XP_003817831
UniProt: A0A2R9BCY1
Position
19
AA seq 662 aa
MGPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRY
ECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWAR
NQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSP
WKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRRLGSQGSSWSKWSSPVCVPPENPPQPQ
VRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRT
LHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADSHTEPVALNISVGTNGTTMYWPA
RAQSTTYCIEWQPVGQDGGLATCNLTAPQDPDPAGMATYSWSRESGAMGQEKCYYITIFA
SAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKE
YVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIE
VQVSDWLIFFASLGSFLSILLVGVLGYLGLNRAARHLCPPLPTPCASSAIEFPGGKETWQ
WINPVDFQEEASLQQALVVEMSWDKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKA
KM
NT seq 1989 nt   +upstreamnt  +downstreamnt
atggggccgctggtgacctgggtggtccccctcctcttcctcttcctgctgtccaggcag
ggtgctgcctgcagaaccagtgagtgctgttttcaggacccgccatatccggatgcagac
tcaggctcggcctcgggccctagggacctgagatgctatcggatatccagtgatcgttac
gagtgctcctggcagtatgagggtcccacagctggggtcagccacttcctgcggtgttgc
cttagctccgggcgctgctgctacttcgccgccggctcagccaccaggctgcagttctcc
gaccaggctggggtgtctgtgctgtacactgtcacactctgggtggaatcctgggccagg
aaccagacagagaagtctcctgaggtgaccctgcagctctacaactcagttaaatatgag
cctcctctgggagacatcaaggtgtccaagttggccgggcagctgcgtatggagtgggag
accccggataaccaggttggtgctgaggtgcagttccggcaccggacacccagcagccca
tggaagttgggcgactgcggacctcaggatgatgatactgagtcctgcctctgccccctg
gagatgaatgtggcccaggaattccagctccgacgacggcggctggggagccaaggaagt
tcctggagcaaatggagcagccccgtgtgtgttccccctgaaaaccccccacagcctcag
gtgagattctcggtggagcagctgggccaggatgggaggaggcggctgaccctgaaagag
cagccaacccagctggagcttccagaaggctgtcaagggctggcacctggcacggaggtc
acttaccgactgcagctccacatgctgtcctgcccgtgtaaggccaaggccaccaggacc
ctgcacctggggaagatgccctatctctcgggtgctgcctacaacgtggctgtcatctcc
tcgaaccaatttggtcctggcctgaaccagacgtggcacattcctgccgacagccacaca
gaaccagtggctctgaatatcagcgtcggaaccaacgggaccaccatgtattggccagcc
cgggctcagagcacgacgtattgcattgaatggcagcccgtgggccaggacgggggcctt
gccacctgcaacctgactgcaccgcaagacccggatccggctggaatggcaacctacagc
tggagtcgagagtctggggcaatggggcaggaaaagtgttactacattaccatctttgcc
tctgcgcaccccgagaagctcaccttgtggtctacggtcctgtccacctaccactttggg
ggcaatgcctcagcggctgggacaccgcaccacgtctcggtgaagaatcatagcttggac
tctgtgtctgtggactgggcaccatccctgctgagcacctgtcccggagtcctaaaggag
tatgttgtccgctgccgagatgaagacagcaaacaggtgtcagagcatcccgtgcagccc
acagagacccaagttaccctcagtggcctgcgggctggtgtagcctacacggtgcaggtg
cgagcagacacagcgtggctgaggggtgtctggagccagccccagcgcttcagcattgaa
gtgcaggtttctgattggctcatcttcttcgcctccctggggagcttcctgagcatcctt
ctcgtgggcgtccttggctaccttggcctgaacagggccgcacggcacctgtgcccaccg
ctgcccacaccctgtgccagctccgccattgagttccctggagggaaggagacttggcag
tggatcaacccagtggacttccaggaagaggcatccctgcagcaggccctggtggtagag
atgtcctgggacaaaggcgagaggactgagcctctcgagaagacagagctacctgagggt
gcccctgagctggccctggatacagagttgtccttggaggatggagacaggtgcaaggcc
aagatgtga

KEGG   Pan paniscus (bonobo): 100980274
Entry
100980274         CDS       T02283                                 

Gene name
EPOR
Definition
(RefSeq) erythropoietin receptor
  KO
K05079  erythropoietin receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100980274 (EPOR)
   04151 PI3K-Akt signaling pathway
    100980274 (EPOR)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100980274 (EPOR)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100980274 (EPOR)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100980274 (EPOR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100980274 (EPOR)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  Prolactin receptor family
   100980274 (EPOR)
SSDB
Motif
Pfam: EpoR_lig-bind fn3
Other DBs
NCBI-GeneID: 100980274
NCBI-ProteinID: XP_003830541
UniProt: A0A2R9AWD4
Position
19
AA seq 508 aa
MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL
VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL
ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY
EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV
SLLTPSDLDPLILTLSLILVLILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH
KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG
SEHAQDTYLVLDKWLLPQNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS
AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL
SDGPYSNPYENSLIPAAEPLPPSYVACS
NT seq 1527 nt   +upstreamnt  +downstreamnt
atggaccacctcggggcgtccctctggccccaggtcggctccctttgtctcctgctcgct
ggggccgcctgggcgcccccgcctaacctcccggaccccaagttcgagagcaaagcggcc
ttgctggcggcccgggggcccgaagagcttctgtgcttcaccgagaggttggaggacttg
gtgtgtttctgggaggaagcggcgagcgctggggtgggcccgggcaactacagcttctcc
taccagctcgaggatgagccatggaagctgtgtcgcctgcaccaggctcccacggctcgt
ggtgcggtgcgcttctggtgttcgctgcctacagccgacacgtcgagcttcgtgccccta
gagttgcgcgtcacagcagcctccggcgctccgcgatatcaccgtgtcatccacatcaat
gaagtagtgctcctagacgcccccgtggggctggtggcgcggttggctgacgagagcggc
cacgtagtgttgcgctggctcccgccgcctgagacacccatgacgtcccacatccgctac
gaggtggacgtctcggccggcaacggcgcagggagcgtacagagggtggagatcctggag
ggccgcaccgagtgtgtgctgagcaacctgcggggccggacgcgctacaccttcgccgtc
cgcgcgcgtatggctgagccgagcttcggcggcttctggagcgcctggtcggagcctgtg
tcgctgctgacgcctagcgacctggaccccctcatcctgacgctctccctcatcctcgtg
ctcatcctggtgctgctgaccgtgctcgcgctgctctcccaccgccgggctctgaagcag
aagatctggcctggcatcccgagcccagagagcgagtttgaaggcctcttcaccacccac
aagggtaacttccagctgtggctgtaccagaatgatggctgcctgtggtggagcccctgc
acccccttcacggaggacccacctgcttccctggaagtcctctcagagcgctgctggggg
acgatgcaggcagtggagccggggacagatgatgagggccccctgctggagccagtgggc
agtgagcatgcccaggatacctatctggtgctggacaaatggttgctgccccagaacccg
cccagtgaggacctcccagggcctggtggcagtgtggacatagtggccatggatgaaggc
tcagaagcatcctcctgctcatctgctttggcctcgaagcccagcccagagggagcctct
gctgccagctttgagtacactatcctggaccccagctcccagctcttgcgtccatggaca
ctgtgccctgagctgccccctaccccaccccacctaaagtacctgtaccttgtggtatct
gactctggcatctcaactgactacagctcaggggactcccagggagcccaagggggctta
tccgatggcccctactccaacccttatgagaacagccttatcccagccgctgagcctctg
ccccccagctatgtggcttgctcttag

KEGG   Pan paniscus (bonobo): 100980367
Entry
100980367         CDS       T02283                                 

Gene name
GHR
Definition
(RefSeq) growth hormone receptor
  KO
K05080  growth hormone receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04080  Neuroactive ligand-receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04935  Growth hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100980367 (GHR)
   04151 PI3K-Akt signaling pathway
    100980367 (GHR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100980367 (GHR)
   04060 Cytokine-cytokine receptor interaction
    100980367 (GHR)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    100980367 (GHR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100980367 (GHR)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  Prolactin receptor family
   100980367 (GHR)
SSDB
Motif
Pfam: GHBP EpoR_lig-bind fn3
Other DBs
NCBI-GeneID: 100980367
NCBI-ProteinID: XP_003811031
Position
5
AA seq 638 aa
MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPE
RETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTS
IWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRN
ADIQKGWMVLEYELQYKEVNETKWKMMDPILSTSVPVYSLKVDKEYEVRVRSKQRNSGNY
GEFSEVLYVTLPQMNQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPP
VPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEGS
DTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGE
ADLLCLDQKNQNNSPYHDVCPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSS
LANIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADA
KKCIPVAPHIKVESHIQPSFNQEDIYITTESLTTAAGRPGTAEHVPGSEMPVPDYTSIHI
VQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
NT seq 1917 nt   +upstreamnt  +downstreamnt
atggatctctggcagctgctgttgaccttggcactggcaggatcaagtgatgctttttct
ggaagtgaggccacagcagctatccttagcagagcaccctggagtctgcaaagtgttaat
ccaggcctaaagacaaattcttctaaggagcctaaattcaccaagtgccgttcacctgag
cgagagactttttcatgccactggacagatgaggttcatcatggtacaaagaacctagga
cccatacagctgttctataccagaaggaacactcaagaatggactcaagaatggaaagaa
tgccctgattatgtttctgctggggaaaacagctgttactttaattcatcgtttacctcc
atctggataccttattgtatcaagctaactagcaatggtggtacagtggatgaaaagtgt
ttctctgttgatgaaatagtgcaaccagatccacccattgccctcaactggactttactg
aacgtcagtttaactgggattcatgcagatatccaagtgagatgggaagcaccacgcaat
gcagatattcagaaaggatggatggttctggagtatgaacttcaatacaaagaagtaaat
gaaactaaatggaaaatgatggaccctatattgtcaacatcagttccagtgtactcattg
aaagtggataaggaatatgaagtgcgtgtgagatccaaacaacgaaactctggaaattat
ggcgagttcagtgaggtgctctatgtaacacttcctcagatgaaccaatttacatgtgaa
gaagatttctactttccatggctcttaattattatctttggaatatttgggctaacagtg
atgctatttgtattcttattttctaaacagcaaaggattaaaatgctgattctgccccca
gttccagttccaaagattaaaggaatcgatccagatctcctcaaggaaggaaaattagag
gaggtgaacacaatcttagccattcatgatagctataaacccgaattccacagtgatgac
tcttgggttgaatttattgagctagatattgatgagccagatgaaaagactgagggatca
gacacagacagacttctaagcagtgaccatgagaaatcacatagtaacctaggggtgaag
gatggcgactctggacgtaccagctgttgtgaacctgacattctggagactgatttcaat
gccaatgacatacatgagggtacctcagaggttgctcagccacagaggttaaaaggggaa
gcagatctcttatgccttgaccagaagaatcaaaataactcaccttatcatgatgtttgc
cctgctactcagcagcccagtgttatccaagcagagaaaaacaaaccacaaccacttcct
actgaaggagctgagtcaactcaccaagctgcccatattcagctaagcaatccaagttca
ctggcaaacatcgacttttatgcccaggtgagcgacattacaccagcaggtagtgtggtc
ctttccccaggccaaaagaataaggcagggatgtcccagtgtgacatgcacccggaaatg
gtctcactctgccaagaaaacttccttatggacaatgcctacttctgtgaggcagatgcc
aaaaagtgcatccctgtggctcctcacatcaaggttgaatcacacatacagccaagcttt
aaccaagaggacatttacatcaccacagaaagccttaccactgctgctgggaggcctggg
acagcagaacatgttccaggttctgagatgcctgtcccagactatacctccattcatata
gtacagtccccacagggcctcatactcaatgcgactgccttgcccttgcctgacaaagag
tttctctcatcgtgtggctatgtgagcacagaccaactgaacaaaatcatgccttag

KEGG   Pan paniscus (bonobo): 100980819
Entry
100980819         CDS       T02283                                 

Gene name
CSF2RA
Definition
(RefSeq) colony stimulating factor 2 receptor alpha subunit
  KO
K05066  granulocyte-macrophage colony-stimulating factor receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100980819 (CSF2RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100980819 (CSF2RA)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100980819 (CSF2RA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100980819 (CSF2RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100980819 (CSF2RA)
   04090 CD molecules [BR:pps04090]
    100980819 (CSF2RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL3 receptor family
   100980819 (CSF2RA)
CD molecules [BR:pps04090]
 Proteins
  100980819 (CSF2RA)
SSDB
Motif
Pfam: IL6Ra-bind IL3Ra_N
Other DBs
NCBI-GeneID: 100980819
NCBI-ProteinID: XP_003809710
Position
Un
AA seq 239 aa
MLLLVTSLLLCELPHPAFLLIPGKSGKYGNLAEPSPRPLFRCPASGDLSGYLSNNECSCT
FREICLHGGVTFEVHVNTSQRGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGP
AAPRDVQYFLYIQNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIG
IQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKV
NT seq 718 nt   +upstreamnt  +downstreamnt
atgcttctcctggtgacaagccttctgctctgtgagttaccacacccagcattcctcctg
atcccagggaaatcgggtaagtatggaaacctggctgaaccttctccgcggcccctgttt
agatgtcctgcatctggagacctatctggatacctcagtaacaacgaatgttcgtgcaca
tttcgtgaaatctgtctgcatggaggagtcacatttgaggttcacgtgaatactagtcaa
agaggatttcaacagaaactgctttatccaaattcaggaagggagggtactgctgctcag
aatttctcctgtttcatctacaatgcggatttaatgaactgcacctgggcgaggggtccg
gcggccccccgtgacgtccagtattttttgtacatacaaaactcaaagagaaggagggag
atccggtgtccttattacatacaagactcaggaacccatgtgggatgtcacctggataac
ctgtcaggattaacgtctcgcaattactttctggttaacggaaccagccgagaaattggc
atccaattctttgattcacttttggacacaaagaaaatagaacgattcaaccctcccagc
aatgtcaccgtacgttgcaacacgacgcactgcctcgtacggtggaaacagcccaggacc
tatcagaagctgtcgtacctggactttcagtaccagctggacgtccacagaaaggtcg

KEGG   Pan paniscus (bonobo): 100980904
Entry
100980904         CDS       T02283                                 

Gene name
IL23R
Definition
(RefSeq) interleukin 23 receptor
  KO
K05065  interleukin 23 receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04659  Th17 cell differentiation
pps05200  Pathways in cancer
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100980904 (IL23R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100980904 (IL23R)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100980904 (IL23R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100980904 (IL23R)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100980904 (IL23R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100980904 (IL23R)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100980904 (IL23R)
SSDB
Motif
Pfam: IL12p40_C fn3 IL6Ra-bind Lep_receptor_Ig
Other DBs
NCBI-GeneID: 100980904
NCBI-ProteinID: XP_003807002
UniProt: A0A2R8ZPL6
Position
1
AA seq 629 aa
MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYMDTKYVVHVKSLETEEEQQYLTSSYIN
ISTDSLQGGKKYLVWVQAANALGMEESKQLQIYLDDIVIPSASVISRAETINATVPKTII
YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
KRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
IVFAVMLSILSLIGIFNRSLRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYLQNSLFDNTTVVYIPDL
NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
VNEELPSINTYFPQNILESHFNRISLLEK
NT seq 1890 nt   +upstreamnt  +downstreamnt
atgaatcaggtcactattcaatgggatgcagtaatagccctttacatactcttcagctgg
tgtcatggaggaattacaaatataaactgctctggccacatctgggtagaaccagccaca
atttttaagatgggaatgaatatctctatatattgccaagcagcaattaagaactgccaa
ccaaggaaacttcatttttataaaaatggcatcaaagaaagatttcaaatcacaaggatt
aataaaacgacagctcggctttggtataaaaattttctggaaccacatgcttctatgtac
tgcactgctgaatgtcccaaacattttcaagagacactgatatgtggaaaagacatttct
tctggatatccgccagatattcctgatgaagtaacctgtgtcatttatgaatattcaggc
aacatgacttgcacctggaatgctgggaagctcacctacatggacacaaaatacgtggta
catgtgaagagtttagagacagaagaagagcaacagtatctcacctcaagctatattaac
atctccactgattcattacaaggtggcaagaagtacttggtttgggtccaagcagcaaac
gcactaggcatggaagaatcaaagcaactgcaaatttacctggatgatatagtgatacct
tctgcatccgtcatttccagggctgagactataaatgctacagtgcccaagaccataatt
tattgggatagtcaaacaacaattgaaaaggtttcctgtgaaatgagatacaaggctaca
acaaaccaaacttggaatgttaaagaatttgacaccaattttacatatgtgcaacagtca
gaattctacttggagccaaacattaagtacgtatttcaagtgagatgtcaagaaacaggc
aaaaggtactggcagccttggagttcaccgttttttcataaaacacctgaaacagttccc
caggtcacatcaaaagcattccaacatgacacatggaattctgggctaacagttgcttcc
atctctacagggcaccttacttctgacaacagaggagacattggacttttattgggaatg
atcgtctttgctgttatgttgtcaattctttctttgattgggatatttaacagatcactc
cgaactgggattaaaagaaggatcttattgttaataccaaagtggctttatgaagatatt
cctaatatgaaaaacagcaatgttgtgaaaatgctacaggaaaatagtgaacttatgaat
aataattccagtgagcaggtcctatatgttgatcccatgattacagagataaaagaaatc
ttcatcccagaacacaagcctacagactacaagaaggagaatacaggacccctggagaca
agagactacctgcaaaactcgctattcgacaatactacagttgtatatattcctgatctc
aacactggatataaaccccaaatttcaaattttctgcctgagggaagccatctcagcaat
aataatgaaattacttccttaacacttaaaccaccagttgattccttagactcaggaaat
aatcccaggttacaaaagcatcctaattttgctttttctgtttcaagtgtgaattcacta
agcaacacaatatttcttggagaattaagcctcatattaaatcaaggagaatgcagttct
cctgacatacaaaactcagtagaggaggaaaccaccatgcttttggaaaatgattcaccc
agtgaaactattccagaacagaccctgcttcctgatgaatttgtctcctgtttgggaatc
gtgaatgaggagttgccatctattaatacttattttccacaaaatattttggaaagccac
ttcaataggatttcactcttggaaaagtag

KEGG   Pan paniscus (bonobo): 100981146
Entry
100981146         CDS       T02283                                 

Gene name
CRLF2
Definition
(RefSeq) cytokine receptor-like factor 2
  KO
K05078  thymic stromal-derived lymphopoietin receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100981146 (CRLF2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100981146 (CRLF2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100981146 (CRLF2)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100981146 (CRLF2)
SSDB
Motif
Pfam: IL6Ra-bind DUF3592
Other DBs
NCBI-GeneID: 100981146
NCBI-ProteinID: XP_003809711
Position
Un
AA seq 161 aa
MGRLVLLRGAAVFLLGGWMALGQGGAAEGVQIQIIYFNLETVQVTWNASKYSRTNLTFHY
RFDGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPS
SPKHVRFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQ
NT seq 483 nt   +upstreamnt  +downstreamnt
atggggcggctggttctgctgcggggagctgccgtctttctgctgggaggctggatggct
ttggggcaaggaggagcagcagaaggagtacagattcagatcatctacttcaatttagaa
accgtgcaggtgacatggaatgccagcaaatactccaggaccaacctgactttccactac
agattcgacggtgatgaggcctatgaccagtgcaccaactaccttctccaggaaggtcac
acttcggggtgcctcctagacgcagagcagcgagacgacattctctatttctccatcagg
aatgggacgcaccccgttttcaccgcaagtcgctggatggtttattacctgaaacccagt
tccccgaagcacgtgagattttcgtggcatcaggacgcagtgacggtgacgtgctctgac
ctgtcctacggtgatctcctctatgaggttcagtaccggagccccttcgacaccgagtgg
cag

KEGG   Pan paniscus (bonobo): 100981232
Entry
100981232         CDS       T02283                                 

Gene name
IL7R
Definition
(RefSeq) interleukin 7 receptor
  KO
K05072  interleukin 7 receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04068  FoxO signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05200  Pathways in cancer
pps05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100981232 (IL7R)
   04068 FoxO signaling pathway
    100981232 (IL7R)
   04151 PI3K-Akt signaling pathway
    100981232 (IL7R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100981232 (IL7R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100981232 (IL7R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100981232 (IL7R)
  09163 Immune disease
   05340 Primary immunodeficiency
    100981232 (IL7R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100981232 (IL7R)
   04090 CD molecules [BR:pps04090]
    100981232 (IL7R)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100981232 (IL7R)
CD molecules [BR:pps04090]
 Proteins
  100981232 (IL7R)
SSDB
Motif
Pfam: FN3_7 fn3
Other DBs
NCBI-GeneID: 100981232
NCBI-ProteinID: XP_003806710
UniProt: A0A2R9BVL0
Position
5
AA seq 459 aa
MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFE
DPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKK
IDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWMH
VNLSSTKLTLLQRKLQPAAKYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDP
ILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNP
ESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPSCPSEDVVNTPES
FGRDSSLTCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFS
LQSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ
NT seq 1380 nt   +upstreamnt  +downstreamnt
atgacaattctaggtacaacttttggcatggttttttctttacttcaagtcgtttctgga
gaaagtggctatgctcaaaatggagacttggaagatgcagaactggatgactactcattc
tcatgctatagccagttggaagtgaatggatcgcagcactcactgacctgtgcttttgag
gacccagatgtcaacaccaccaatctggaatttgaaatatgtggggccctcgtggaggta
aagtgcctgaatttcaggaaactacaagagatatatttcatcgagacaaagaaattctta
ctgattggaaagagcaatatatgtgtgaaggttggagaaaagagtctaacctgcaaaaaa
atagacctaaccactatagttaaacctgaggctccttttgacctgagtgtcatctatcgt
gaaggagccaatgactttgtggtgacatttaatacatcacacttgcaaaagaagtatgta
aaagttttaatgcatgatgtagcttaccgccaggaaaaggatgaaaacaaatggatgcat
gtgaatttatccagcacaaagctgacactcctgcagagaaagctccaaccagcagcaaag
tatgagattaaagttcgatccatccctgatcactattttaaaggcttctggagtgaatgg
agtccaagttattacttcagaactccagagatcaataatagctcaggggagatggatcct
atcttactaaccatcagcattttgagttttttctctgtcgctctgttggtcatcttggcc
tgtgtgttatggaaaaaaaggattaagcctatcgtatggcccagtctccccgatcataag
aagactctggaacatctttgtaagaaaccaagaaaaaatttaaatgtgagtttcaatcct
gaaagtttcctggactgccagattcatagggtggatgacattcaagctagagatgaagtg
gaaggttttctgcaagatacgtttcctcagcaactagaagaatctgagaagcagaggctt
ggaggggatgtgcagagccccagctgcccatctgaggatgtagtcaacactccagaaagc
tttggaagagattcatccctcacatgcctggctgggaatgtcagtgcatgtgacgcccct
attctctcctcttccaggtcactagactgcagggagagtggcaagaatgggcctcatgtg
taccaggacctcctgcttagccttgggactacaaacagcacgctgccccctccattttct
ctccaatctggaatcctgacattgaacccagttgctcagggtcagcccattcttacttcc
ctgggatcaaatcaagaagaagcatatgtcaccatgtccagcttctaccaaaaccagtga

KEGG   Pan paniscus (bonobo): 100982237
Entry
100982237         CDS       T02283                                 

Gene name
PRLR
Definition
(RefSeq) prolactin receptor
  KO
K05081  prolactin receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04080  Neuroactive ligand-receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04917  Prolactin signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100982237 (PRLR)
   04151 PI3K-Akt signaling pathway
    100982237 (PRLR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100982237 (PRLR)
   04060 Cytokine-cytokine receptor interaction
    100982237 (PRLR)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    100982237 (PRLR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100982237 (PRLR)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  Prolactin receptor family
   100982237 (PRLR)
SSDB
Motif
Pfam: EpoR_lig-bind fn3 IL6Ra-bind GHBP
Other DBs
NCBI-GeneID: 100982237
NCBI-ProteinID: XP_003806712
UniProt: A0A2R9CSZ3
Position
5
AA seq 622 aa
MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPVTFIQIPSDFTMNDTTVWIS
VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
ENSKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
KCRLQLGGLDYLDPACFTHSFH
NT seq 1869 nt   +upstreamnt  +downstreamnt
atgaaggaaaatgtggcatctgcaaccgttttcactctgctactttttctcaacacctgc
cttctgaatggacaattacctcctggaaaacctgagatctttaaatgtcgttctcccaat
aaggaaacattcacctgctggtggaggcctgggacagatggaggacttcctaccaattat
tcactgacttaccacagggaaggagagacactcatgcatgaatgtccagactacataacc
ggtggccccaactcctgccactttggcaagcagtacacctccatgtggaggacatacatc
atgatggtcaatgccactaaccagatgggaagcagtttctcggatgaactttatgtggac
gtgacttacatagttcaaccagaccctcctttggagctggctgtggaagtaaaacagcca
gaagacagaaaaccctacctgtggattaaatggtctccacctaccctgattgacttaaaa
actggttggttcacgctcctgtatgaaattcgattaaaacccgagaaagcagctgagtgg
gagatccattttgctgggcagcaaacagagtttaagattctcagcctacatccaggacag
aaataccttgtccaggttcgctgcaaaccagaccatggatactggagcgcgtggagtcca
gtgaccttcattcagatacctagtgacttcaccatgaatgatacaaccgtgtggatctct
gtggctgtcctttctgctgtcatctgtttgattattgtctgggcagtggctttgaagggc
tatagcatggtgacctgcatctttccgccagttcctgggccaaaaataaaaggatttgat
gctcatctgttggagaagggcaagtctgaagaactactgagtgccttgggatgccaagac
tttcctcccacttctgactatgaggacttgctggtggagtatttagaagtagatgatagt
gaggaccagcatctaatgtcagtccattcaaaagaacacccaagtcaaggtatgaaaccc
acatacctggatcctgacactgactcaggccgggggagctgtgacagcccttcccttttg
tctgaaaagtgtgaggaaccccaggccaatccctccacattctatgatcctgaggtcatt
gagaagccagagaatcctgaaacaacccacacctgggacccccagtgcataagcatggaa
ggcaaaatcccctattttcatgctggtggatccaaatgttcaacatggcccctaccacag
cccagccagcacaaccccagatcctcttaccacaatattactgatgtgtgtgagctggct
gtgggccctgcaggtgcaccggccactctgttgaatgaagcaggtaaagatgctttaaaa
tcctctcaaaccattaagtctagagaagagggaaaggcaacccagcagagggaggtagaa
agcttccattccgagactgaccaggatacgccctggctgctgccccaggagaaaaccccc
tttggctccgctaaacccttggattatgtggagattcacaaggtcaacaaagatggtgca
ttatcattgctaccaaaacagagagagaacagcggcaagcccaagaagcccgggactcct
gagaacagtaaggagtatgccaaggtgtccggggtcatggataacaacatcctggtgttg
gtgccagatccacatgctaaaaatgtggcttgctttgaagaatcagccaaagaggcccca
ccatcacttgaacagaatcaagctgagaaagccctggccaacttcactgcaacatcaagc
aagtgcaggctccagctgggtggtttggattacctggatcccgcatgttttacacactcc
tttcactga

KEGG   Pan paniscus (bonobo): 100982337
Entry
100982337         CDS       T02283                                 

Gene name
PDGFRA
Definition
(RefSeq) platelet derived growth factor receptor alpha
  KO
K04363  platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04072  Phospholipase D signaling pathway
pps04144  Endocytosis
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04540  Gap junction
pps04630  JAK-STAT signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05163  Human cytomegalovirus infection
pps05200  Pathways in cancer
pps05206  MicroRNAs in cancer
pps05214  Glioma
pps05215  Prostate cancer
pps05218  Melanoma
pps05230  Central carbon metabolism in cancer
pps05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100982337 (PDGFRA)
   04014 Ras signaling pathway
    100982337 (PDGFRA)
   04015 Rap1 signaling pathway
    100982337 (PDGFRA)
   04630 JAK-STAT signaling pathway
    100982337 (PDGFRA)
   04020 Calcium signaling pathway
    100982337 (PDGFRA)
   04072 Phospholipase D signaling pathway
    100982337 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    100982337 (PDGFRA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100982337 (PDGFRA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100982337 (PDGFRA)
   04540 Gap junction
    100982337 (PDGFRA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100982337 (PDGFRA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100982337 (PDGFRA)
   05206 MicroRNAs in cancer
    100982337 (PDGFRA)
   05230 Central carbon metabolism in cancer
    100982337 (PDGFRA)
   05231 Choline metabolism in cancer
    100982337 (PDGFRA)
  09162 Cancer: specific types
   05214 Glioma
    100982337 (PDGFRA)
   05218 Melanoma
    100982337 (PDGFRA)
   05215 Prostate cancer
    100982337 (PDGFRA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100982337 (PDGFRA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100982337 (PDGFRA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100982337 (PDGFRA)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:pps04090]
    100982337 (PDGFRA)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100982337 (PDGFRA)
Protein kinases [BR:pps01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   100982337 (PDGFRA)
CD molecules [BR:pps04090]
 Proteins
  100982337 (PDGFRA)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 I-set ig Ig_2 V-set Herpes_gE Ig_6 C2-set_2 Kinase-like
Other DBs
NCBI-GeneID: 100982337
NCBI-ProteinID: XP_003806509
UniProt: A0A2R9AK21
Position
4
AA seq 1089 aa
MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVSASYNSRQGFNG
TFTVGPYICEATVNGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVK
EMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKNNLTLIENL
TEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNLSNIITEIHPRD
RSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq 3270 nt   +upstreamnt  +downstreamnt
atggggacttcccatccggcgttcctggtcttaggctgtcttctcacagggctgagccta
atcctctgccagctttcattaccctctatccttccaaatgaaaatgaaaaggttgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagagctccgatgtggaaatcagaaatgaagaaaacaacagcggcctt
tttgtgacggtcttggaagtgagcagtgcctcggcggcccacacagggttgtacacttgc
tattacaaccacactcagacagaagagaatgagcttgaaggcaggcacatttacatctat
gtgccagacccagatgtagcctttgtacctctaggaatgacggattatttagtcatcgtg
gaggatgatgattctgccattataccttgtcgcacaactgatcccgagactcctgtaacc
ttacacaacagtgagggggtggtatctgcctcctacaacagcagacagggctttaatggg
accttcactgtagggccctatatctgtgaggccaccgtcaacggaaagaagttccagacc
atcccatttaacgtttatgctttaaaagcaacatcagagctggatctagaaatggaagct
cttaaaaccgtgtataagtcaggggaaacgattgtggtcacctgtgctgtttttaacaat
gaggtggttgaccttcaatggacttaccctggagaagtgaaaggcaaaggcatcacaatg
ctggaagaaatcaaagtcccatccatcaaattggtgtacactttgacggtccccgaggcc
acggtgaaagacagtggagattacgaatgtgctgcccgccaggctaccagggaggtcaaa
gaaatgaagaaagtcactatttctgtccatgagaaagggttcattgaaatcaaacccacc
ttcagccagttggaagctgtcaacctgcatgaagtcaaacattttgttgtagaggtgcgg
gcctacccacctcccaggatatcctggctgaaaaacaatctgactctgattgaaaatctc
actgagatcaccactgatgtggaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaagaagacagtggccattatactattgtagctcaaaatgaagat
gctgtgaagagctatacttttgaactgttaactcaggttccttcatccattctggacttg
gtcgatgatcaccacggctcaactgggggacagacggtgaggtgcacagctgaaggcacg
ccgcttcctgatattgagtggatgatatgcaaggatattaagaaatgtaataatgaaact
tcctggacgattttggccaacaatctctcaaacatcatcacggagatccacccccgagac
aggagtaccgtggagggccgtgtgactttcgccaaagtggaggagaccatcgcggtgcga
tgcctggctaagaatctccttggagctgagaaccgagagctgaagctggtggctcccacc
ctgcgttctgaactcaccgtggctgctgcagtcctggtgctgttggtgattgtgatcatc
tcacttattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatcaatcagcccagatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcaagatgggagtttccaagagatggactagtgcttggtcgggtcttgggg
tctggagcgtttgggaaggtggttgaaggaacagcctatggattaagccggtcccaacct
gtcatgaaagttgcagtgaagatgctaaaacccacggccagatccagtgaaaaacaagct
ctcatgtctgaactgaagataatgactcacctggggccacatttgaacattgtaaacttg
ctgggagcctgcaccaagtcaggccccatttacatcatcacagagtattgcttctatgga
gatttggtcaactatttgcataagaatagggatagcttcctgagccaccacccagagaag
ccaaagaaagagctggatatctttggattgaaccctgctgatgaaagcacacggagctat
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaggctgatactaca
caatatgtccccatgctagaaaggaaagaggtttctaaatattccgacatccagagatca
ctctatgatcgtccagcctcatataagaagaaatctatgttagactcagaagtcaaaaac
ctcctttcagatgataactcagaaggccttactttattggatttgttgagcttcacctat
caagttgcccgaggaatggagtttttggcttcaaaaaattgtgtccaccgtgatctggct
gctcgcaacgtcctcctggcacaaggaaaaatcgtgaagatctgtgactttggcctggcc
agagacatcatgcatgattcgaactatgtgtcgaaaggcagtacctttctgcccgtgaag
tggatggctcctgagagcatctttgacaacctctacaccacactgagtgatgtctggtct
tacggcattctgctctgggagatcttttcccttggtggcaccccttaccccggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccac
gctaccagtgaagtctacgagatcatggtgaaatgctggaacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgctgcctggacaatataaaaag
agttatgaaaaaattcacctggacttcctgaagagtgaccatcctgctgtggcacgcatg
cgtgtggactcagacaatgcatacattggtgtcacctacaaaaacgaggaagacaagctg
aaggactgggagggtggtctggatgagcagagactgagcgctgacagtggctacatcatt
cctctgcctgacattgaccctgtccctgaggaggaggacctgggcaagaggaacagacac
agctcgcagacctctgaagagagtgccattgagacgggttccagcagttccaccttcatc
aagagagaggacgagaccattgaagacatcgacatgatggacgacatcggcatagactct
tcagacctggtggaagacagcttcctgtaa

KEGG   Pan paniscus (bonobo): 100982658
Entry
100982658         CDS       T02283                                 

Gene name
IL10RA
Definition
(RefSeq) interleukin 10 receptor subunit alpha
  KO
K05134  interleukin 10 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
pps05145  Toxoplasmosis
pps05152  Tuberculosis
pps05163  Human cytomegalovirus infection
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100982658 (IL10RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100982658 (IL10RA)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100982658 (IL10RA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100982658 (IL10RA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100982658 (IL10RA)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100982658 (IL10RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100982658 (IL10RA)
   04090 CD molecules [BR:pps04090]
    100982658 (IL10RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL10/28 receptor family
   100982658 (IL10RA)
CD molecules [BR:pps04090]
 Proteins
  100982658 (IL10RA)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind
Other DBs
NCBI-GeneID: 100982658
NCBI-ProteinID: XP_003820111
UniProt: A0A2R9ANB8
Position
11
AA seq 578 aa
MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVA
LLRYGIESWNSISNCSQTLSYDLTAVTLDLYRSNGYRARVRAVDGSRHSNWTVTNTRFSV
DEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTF
THKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECVSLTRQYFTVTNVIIFF
AFVLLLSGALAYCLALQLYVRRRKKLPSVLLFKKPSPFIFISQRPSPETQDTIHPLDEEA
FLKVSPELKNLDLHGSTDSGFGSTKPSLQTEEPQFLLPDPHPQADRTLGNGEPPVLGDSC
SSGSSNSTDSGICLQEPGLSPSTGPTWEQQVGSNSRGQDDSGIGLVQNSEGRAGDTQRGS
ALGHHSPPEPEVPGEEDPAAVAFQGYLRQTRCAEEKATKTGCREEESPLTDGLGPKFGRC
LVDEAGLHPPALAKGYLKQDPLEMTLASSGAPTGQWNQPTEEWSLLALSSCSDLGISDWS
FAHDLAPLGCVAAPGGLLGSFNSDLVTLPLISSLQSSE
NT seq 1737 nt   +upstreamnt  +downstreamnt
atgctgccgtgcctcgtagtgctgctggcggcgctcctcagcctccgtcttggctcagac
gctcatgggacagagctgcccagccctccgtctgtgtggtttgaagcagaatttttccac
cacatcctccactggacacccatcccaaatcagtctgaaagtacctgctatgaagtggcg
ctcctgaggtatggaatagagtcctggaactccatctccaactgtagccagaccctgtcc
tatgaccttaccgcagtgaccttggacctgtaccgcagcaatggctaccgggccagagtg
cgggctgtggacggcagccggcactccaactggaccgtcaccaacacccgcttctctgtg
gatgaagtgactctgacagttggcagtgtgaacctagagatccacaatggcttcatcctc
gggaagattcagctacccaggcccaagatggcccccgcaaatgacacatatgaaagcatc
ttcagtcacttccgagagtatgagattgccattcgcaaggtgccgggaaacttcacgttc
acacacaagaaagtaaaacatgaaaacttcagcctcctaacctctggagaagtgggagag
ttctgtgtccaggtgaaaccatctgtcgcttcccgaagtaacaaggggatgtggtctaaa
gaggagtgcgtctccctcaccaggcagtatttcaccgtgaccaacgtcatcatcttcttt
gcctttgtcctgctgctctccggagccctcgcctactgcctggccctccagctgtatgtg
cggcgccgaaagaagctgcccagtgtcctgctcttcaagaagcccagccccttcatcttc
atcagccagcgtccctccccagagacccaagacaccatccacccgcttgatgaggaggcc
tttctgaaggtgtccccagagctgaagaacttggacctgcacggcagcacagacagtggc
tttggcagcaccaagccatccctgcagactgaagagccccagttcctcctccctgaccct
cacccccaggctgacagaacgctgggaaacggggagccccctgtgctgggggacagctgc
agtagtggcagcagcaatagcacggacagcgggatctgcctgcaggagcccggcctgagc
cccagcacagggcccacctgggagcaacaggtggggagcaacagcaggggccaggatgac
agtggcattggcctagttcaaaactctgagggccgggctggggacacacagcgtggctca
gccttgggccaccacagtcccccagagcctgaggtgcctggggaagaagacccagctgct
gtggcattccagggctacttgaggcagaccagatgtgctgaagagaaggcaaccaagaca
ggctgccgggaggaagaatctcccttgacagatggccttggccccaaattcgggagatgc
ctggttgatgaggcaggcttgcatccaccagccctggccaagggctatttgaaacaggat
cctctagaaatgactctggcttcctcaggggccccaacgggacagtggaaccagcccact
gaggaatggtcactcctggccttgagcagctgcagtgacctgggaatatctgactggagc
tttgcccatgaccttgcccctctaggctgtgtggcagccccaggtggtctcctgggcagc
tttaactcagacctggtcaccctgcccctcatctctagcctgcagtcaagtgagtga

KEGG   Pan paniscus (bonobo): 100984257
Entry
100984257         CDS       T02283                                 

Gene name
IL12RB2
Definition
(RefSeq) interleukin 12 receptor subunit beta 2
  KO
K05064  interleukin 12 receptor beta-2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps05200  Pathways in cancer
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100984257 (IL12RB2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100984257 (IL12RB2)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100984257 (IL12RB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100984257 (IL12RB2)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100984257 (IL12RB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100984257 (IL12RB2)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100984257 (IL12RB2)
SSDB
Motif
Pfam: fn3
Other DBs
NCBI-GeneID: 100984257
NCBI-ProteinID: XP_003807011
Position
1
AA seq 594 aa
MVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVW
YMKMHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIP
RTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDP
SAVQEYVVEWRELHPGGDTQVPLNWLRSPPYNVSALISENIKSYICYEIRVYALSGDQGG
CSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQ
PQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVA
PSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLP
LDRLLIDWPTPEDPEPLVISEVLHQVTPVFRRPPCSNWPQREKGIQGHQASEKDMMHSAS
SPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDL
PSHEAPLADSLEELEPQHISLSVFPSSSLHPLTFSCGDKLTLDQLKMRCDSLML
NT seq 1785 nt   +upstreamnt  +downstreamnt
atggttaatgttacaaaggccaaaggaagacatgatttgctggatctgaaaccatttaca
gaatatgaatttcagatttcctctaagctacatctttataagggaagttggagtgattgg
agtgaatcattgagagcacaaacaccagaagaagagcctactgggatgttagatgtctgg
tacatgaaaatgcacattgactacagtagacaacagatttctcttttctggaagaatctg
agtgtctcagaggcgagaggaaaaattctccactatcaggtgaccttgcaggagctgaca
ggagggaaagccatgacacagaacatcacaggacacacctcctggaccacagtcattcct
agaaccggaaattgggctgtggctgtgtctgcagcaaattcaaaaggcagttctctgccc
actcgtattaacataatgaacctgtgtgaggcagggttgctggctcctcgccaggtctct
gcaaactcagagggcatggacaacattctggtgacttggcagcctcccaggaaagatccc
tctgctgttcaggaatacgtggtggaatggagagagctccatccagggggtgacacacag
gtccctctaaactggctacggagtccaccctacaatgtgtctgctctgatttcagagaac
ataaaatcctacatctgttatgaaatccgtgtgtatgcactctcaggggatcaaggagga
tgcagctccatcctgggtaactctaagcacaaagcaccactgagtggcccccacattaat
gccatcacagaggaaaaggggagcattttaatttcatggaacagcattccagtccaggag
caaatgggctgcctcctccattacaggatatactggaaggaacgggactccaactcccag
cctcagctctgtgaaattccctatagagtctcccaaaattcacatccaataaacagcctg
cagccccgagtgacatatgtcctgtggatgacagctctgacagctgctggcgaaagttcc
cacggaaatgagagggaattttgtctgcaaggtaaagccaattggatggcgtttgtggca
ccaagcatttgcattgctatcatcatggtgggcattttctcaacgcattacttccagcaa
aaggtgtttgttctcctagcagccctcagacctcagtggtgtagcagagaaattccagat
ccagcaaatagcacttgtgctaagaaatatcccattgcagaggagaagacacagctgccc
ttggacaggctcctgatagactggcccacgcctgaagatcctgaaccgctggtcatcagt
gaagtccttcatcaagtgaccccagttttcagacgtcccccctgctccaactggccacaa
agggaaaaaggaatccaaggtcatcaggcctctgagaaagacatgatgcacagtgcctca
agcccaccacctccaagagctctccaagctgaaagcagacaactggtggatctgtacaag
gtgctggagagcaggggctcagacccaaagccagaaaacccagcctgtccctggacggtg
ctcccagcaggtgaccttcccacccacgatggctacttaccctccaacatagatgacctc
ccctcacatgaggcgcctctcgctgactctctggaagaactggagcctcagcacatctcc
ctttctgttttcccctcaagttctcttcacccactcaccttctcctgtggtgataagctg
actctggatcagttaaagatgaggtgtgactccctcatgctctga

KEGG   Pan paniscus (bonobo): 100986352
Entry
100986352         CDS       T02283                                 

Gene name
IL13RA2
Definition
(RefSeq) interleukin 13 receptor subunit alpha 2
  KO
K05077  interleukin 13 receptor alpha-2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100986352 (IL13RA2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100986352 (IL13RA2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100986352 (IL13RA2)
   04090 CD molecules [BR:pps04090]
    100986352 (IL13RA2)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL3 receptor family
   100986352 (IL13RA2)
CD molecules [BR:pps04090]
 Proteins
  100986352 (IL13RA2)
SSDB
Motif
Pfam: IL6Ra-bind fn3 EpoR_lig-bind LIFR_N DDE_Tnp_4
Other DBs
NCBI-GeneID: 100986352
NCBI-ProteinID: XP_008969366
UniProt: A0A2R9BPA3
Position
X
AA seq 380 aa
MAFVCLAIGCLYTFLISTTVGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD
HFKECTVEYELKYRNIGSETWKTIVTKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ
SSWAETTYWISPQGIPESKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH
AVQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLP
PVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNE
TRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLLKKTLLRFWVPFGFILILVIFVTG
LLLRKPNTYPKMIPEFFCDT
NT seq 1143 nt   +upstreamnt  +downstreamnt
atggctttcgtttgcttggctatcggatgcttatatacctttctgataagcacaacagtt
ggctgtacttcatcttcagacaccgagataaaagttaaccctcctcaggattttgagata
gtggatcccggatacttaggttatctctatttgcaatggcaacccccactgtctctggat
cattttaaggaatgcacagtggaatatgaactaaaataccgaaacattggtagtgaaaca
tggaagaccatcgttactaagaatctacattacaaagatgggtttgatcttaacaagggc
attgaagcgaagatacacacgcttttaccatggcaatgcacaaatggatcagaagttcaa
agttcctgggcagaaactacttattggatatcaccacaaggaattccagaatctaaagtt
caggatatggattgcgtatattacaactggcaatatttactctgttcttggaaacctggc
ataggtgtacttcttgataccaattacaacttgttttactggtatgagggcttggatcat
gcagtacagtgtgttgattacatcaaggctgatggacaaaatataggatgcagatttccc
tatttggaggcatcagactataaagatttctatatttgtgttaatggatcatcagagaac
aagcctatcagatccagttatttcacttttcagcttcaaaatatagttaaacctttgccg
ccagtctatcttacttttactcgggagagttcatgtgaaattaagctgaaatggagcata
cctttgggacctattccagcaaggtgttttgattatgaaattgagatcagagaagatgat
actaccttggtgactgctacagttgaaaatgaaacatataccttgaaaacaacaaatgaa
acccgacaattatgctttgtagtaagaagcaaagtgaatatttattgctcagatgacgga
atttggagtgagtggagtgataaacaatgctgggaaggtgaagacctattgaagaaaact
ttgctacgtttctgggtaccatttggtttcatcttaatattagttatatttgtaaccggt
ctgcttttgcgtaagccaaacacctacccaaaaatgattccagaatttttctgtgataca
tga

KEGG   Pan paniscus (bonobo): 100986679
Entry
100986679         CDS       T02283                                 

Gene name
IL2RG
Definition
(RefSeq) interleukin 2 receptor subunit gamma
  KO
K05070  interleukin 2 receptor gamma
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04144  Endocytosis
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps05162  Measles
pps05166  Human T-cell leukemia virus 1 infection
pps05200  Pathways in cancer
pps05321  Inflammatory bowel disease
pps05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100986679 (IL2RG)
   04151 PI3K-Akt signaling pathway
    100986679 (IL2RG)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100986679 (IL2RG)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100986679 (IL2RG)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100986679 (IL2RG)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100986679 (IL2RG)
   04659 Th17 cell differentiation
    100986679 (IL2RG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100986679 (IL2RG)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100986679 (IL2RG)
   05162 Measles
    100986679 (IL2RG)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100986679 (IL2RG)
   05340 Primary immunodeficiency
    100986679 (IL2RG)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100986679 (IL2RG)
   04090 CD molecules [BR:pps04090]
    100986679 (IL2RG)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100986679 (IL2RG)
CD molecules [BR:pps04090]
 Proteins
  100986679 (IL2RG)
SSDB
Motif
Pfam: IL6Ra-bind EpoR_lig-bind fn3 IL4Ra_N
Other DBs
NCBI-GeneID: 100986679
NCBI-ProteinID: XP_008971810
UniProt: A0A2R9BYW9
Position
X
AA seq 369 aa
MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTSMPTDSLSVSTLPLPEV
QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK
EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN
HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW
SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV
TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP
PCYTLKPET
NT seq 1110 nt   +upstreamnt  +downstreamnt
atgttgaagccatcattaccattcacatccctcttattcctgcagctgcccctgctggga
gtggggctgaacacgacaattctgacgcccaatgggaatgaagacaccacagctgatttc
ttcctgacctctatgcccactgactccctcagtgtttccactctgcccctcccagaggtt
cagtgttttgtgttcaatgtcgagtacatgaattgcacttggaacagcagctctgagccc
cagcctaccaacctcactctgcattattggtacaagaactcggataatgataaagtccag
aagtgcagccactatctattctctgaagaaatcacttctggctgtcagttgcaaaaaaag
gagatccacctctaccaaacatttgttgttcagctccaggacccacgggaacccaggaga
caggccacacagatgctaaaactgcagaatctggtgatcccctgggctccagagaaccta
acacttcacaaactgagtgaatcccagctagaactgaactggaacaacagattcttgaac
cactgtttggagcacttggtgcagtaccggactgactgggaccacagctggactgaacaa
tcagtggattatagacataagttctccttgcctagtgtggatgggcagaaacgctacacg
tttcgtgttcggagccgctttaacccactctgtggaagtgctcagcattggagtgaatgg
agccacccaatccactgggggagcaatacttcaaaagagaatcctttcctgtttgcattg
gaagccgtggttatctctgttggctccatgggattgattatcagccttctctgtgtgtat
ttctggctggaacggacgatgccccgaattcccaccctgaagaacctagaggatcttgtt
actgaataccacgggaacttttcggcctggagtggtgtgtctaagggactggctgagagt
ctgcagccagactacagtgaacgactctgcctcgtcagtgagattcccccaaaaggaggg
gccctcggggaggggcctggggcctccccatgcaaccagcatagcccctactgggccccc
ccatgttacaccctaaagcctgaaacctga

KEGG   Pan paniscus (bonobo): 100987428
Entry
100987428         CDS       T02283                                 

Gene name
MPL
Definition
(RefSeq) MPL proto-oncogene, thrombopoietin receptor
  KO
K05082  thrombopoietin receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100987428 (MPL)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100987428 (MPL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100987428 (MPL)
   04090 CD molecules [BR:pps04090]
    100987428 (MPL)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  Prolactin receptor family
   100987428 (MPL)
CD molecules [BR:pps04090]
 Proteins
  100987428 (MPL)
SSDB
Motif
Pfam: EpoR_lig-bind fn3 IL6Ra-bind LIFR_N POU2F1_C
Other DBs
NCBI-GeneID: 100987428
NCBI-ProteinID: XP_003812896
UniProt: A0A2R8ZJ08
Position
1
AA seq 635 aa
MPSWALFMVTSCLLLAPQNLAQVSSQDVSLLASDSEPLKCFSRTFEDLTCFWDEEEAAPS
GTYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFPLHLWVKNVFLNQTR
TQRVLFVDSVGLPAPPSIIKAMGGSQPGELQISWEEPAPEISDFLRYELRYGPRDPKNST
GPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDGPKQTSPSREASALTAEGGS
CLISGLQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTVDLPGDAVAIGLQCFTLDLKNVT
CQWQQQDHASSQGFFYHSRARCCPRDRYPIWENCEEEEKTNPGLQTPQFSRCHFKSRNDS
IIHILVEVTTAPGAVHSYLGSPFWIHQAVRLPTPNLHWREISSGHLELEWQHPSSWAAQE
TCYQLRYTGEGHQDWKVLEPPLGARGGTLELRPRSRYRLQLRARLNGPTYQGPWSSWSDP
ARVETATETAWISLVTALHLVLGLSAVLGLLLLRWQFPAHYRRLRHALWPSLPDLHRVLG
QYLRDTAALSPPKATVSDTCEEVEPSLLEILPKSSERTPLPLCSSQAQMDYRRLQPSCLG
TMPLSVCPPMAESGSCCTTHIANHSYLPLSYWQQP
NT seq 1908 nt   +upstreamnt  +downstreamnt
atgccctcctgggccctcttcatggtcacctcctgcctcctcctggcccctcaaaacctg
gcccaagtcagcagccaagatgtctccttgctggcatcagactcagagcccctgaagtgt
ttctcccgaacatttgaggacctcacttgcttctgggatgaggaagaggcagcgcccagt
gggacataccagctgctgtatgcctacccgcgggagaagccccgtgcttgccccctgagt
tcccagagcatgccccactttggaacccgatacgtgtgccagtttccagaccaggaggaa
gtgcgtctcttctttccgctgcacctctgggtgaagaatgtgttcctaaaccagactcgg
actcagcgagtcctctttgtggacagtgtaggcctgccggctccccccagtatcatcaag
gccatgggtgggagccagccaggggaacttcagatcagctgggaggagccagctccagaa
atcagtgatttcctgaggtacgaactccgctatggccccagagatcccaagaactccact
ggtcccacggtcatacagctgatcgccacagaaacctgctgccctgctctgcagaggcct
cactcagcctctgctctggaccagtctccatgtgctcagcccacaatgccctggcaagat
ggaccaaagcagacctccccaagtagagaagcttcagctctgacagcagagggtggaagc
tgcctcatctcaggactccagcctggcaactcctactggctgcagctgcgcagcgaacct
gatgggatctccctcggtggctcctggggatcctggtccctccctgtgactgtggacctg
cctggagatgcagtggcaattggactgcaatgctttaccttggacctgaagaatgttacc
tgtcaatggcagcaacaggaccatgctagctcccaaggcttcttctaccacagcagggca
cggtgctgccccagagacaggtaccccatctgggagaactgcgaagaggaagagaaaaca
aatccaggactacagaccccacagttctctcgctgccacttcaagtcacgaaatgacagc
attattcacatccttgtggaggtgaccacagccccgggtgctgttcacagctacctgggc
tcccctttctggatccaccaggctgtgcgcctccccaccccaaacttgcactggagggag
atctccagtgggcatctggaattggagtggcagcacccatcgtcctgggcagcccaagag
acctgctatcaactccgatacacaggagaaggccatcaggactggaaggtgctggagccg
cctctcggggcccgaggagggaccctggagctgcgcccgcgatctcgctaccgtttacag
ctgcgcgccaggctcaacggccccacctatcaaggtccctggagctcgtggtcggaccca
gctagggtggagaccgccaccgagaccgcctggatctccttggtgaccgctctgcatcta
gtgctgggcctcagcgccgtcctgggcctgctgctgctgaggtggcagtttcctgcacac
tacaggagactgaggcatgccctgtggccctcacttccagacctgcaccgggtcctaggc
cagtaccttagggacactgcagccctgagcccgcccaaggccacagtctcagatacctgt
gaagaagtggaacccagcctccttgaaatcctccccaagtcctcagagaggactcctttg
cccctgtgttcctcccaggcccagatggactaccgaagattgcagccttcttgcctgggg
accatgcccctgtctgtgtgcccacccatggctgagtcagggtcctgctgtaccacccac
attgccaaccattcctacctaccactaagctattggcagcagccttga

KEGG   Pan paniscus (bonobo): 100988608
Entry
100988608         CDS       T02283                                 

Gene name
CSF2RB
Definition
(RefSeq) colony stimulating factor 2 receptor beta common subunit
  KO
K04738  cytokine receptor common subunit beta
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04210  Apoptosis
pps04630  JAK-STAT signaling pathway
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100988608 (CSF2RB)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100988608 (CSF2RB)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100988608 (CSF2RB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100988608 (CSF2RB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100988608 (CSF2RB)
   04090 CD molecules [BR:pps04090]
    100988608 (CSF2RB)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL3 receptor family
   100988608 (CSF2RB)
CD molecules [BR:pps04090]
 Proteins
  100988608 (CSF2RB)
SSDB
Motif
Pfam: fn3 IL4Ra_N IL6Ra-bind EpoR_lig-bind Tissue_fac IL2RB_N1 Interfer-bind Pur_ac_phosph_N
Other DBs
NCBI-GeneID: 100988608
NCBI-ProteinID: XP_003821586
Position
22
AA seq 897 aa
MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT
LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG
TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGGPQSHWLSQGDLEFEVVYKRLQD
SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG
DEAQPQNLQCFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL
HTRHHCQIPVPDPATHGQYIVSVQPRRTEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET
MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG
YNGIWSEWSEARSWDTESVLPMWVLALVVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPN
PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIE
DPKHVCDPPSGSDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSR
SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQALGPGQAVEVERRPSQ
GAAGIPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFT
PHSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRFPRSP
RNNPVPPEAKSPVLNPGERRADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPS
SPGPCPEIRDPDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEINKPGEVC
NT seq 2694 nt   +upstreamnt  +downstreamnt
atggtgctggcccaggggctgctctccatggccctgctggccctgtgctgggagcgcagc
ctggcaggggcagaagaaaccatcccgctgcagaccctgcgctgctacaacgactacacc
agccacatcacctgcaggtgggcagacacccaggatgcccagcggctcgtcaacgtgacc
ctcattcgccgggtgaatgaggaccttctggagccagtgtcctgtgacctcagtgatgac
atgccctggtcagcctgcccccatccccgctgcgtgcccaggagatgtgtcattccctgc
cagagttttgtcgtcactgacgttgactacttctcattccaaccagacaggcctctgggc
acccggctcaccgtcactctgacccagcatgtccagcctcctgagcccagggacctgcag
atcagcaccgaccaggaccacttcctgctgacctggagtgtggcccttgggggtccccag
agccactggttatcccagggggatctggagtttgaggtggtctacaagcggcttcaggac
tcttgggaggacgcagccatcctcctctccaacacctcccaggccaccctggggccagag
cacctcatgcccagcagcacctacgtggcccgagtacggacccgcctggccccaggctct
cggctctcaggacgtcccagcaagtggagcccagaggtttgctgggactcccagccaggg
gatgaggcccagccccagaacctgcagtgcttctttgacggggccgctgtgctcagctgc
tcctgggaggtgaggaaggaggtggccagctcagtctcctttggcctattctacaagccc
agcccagatgcaggggaggaagagtgctccccagtgctgagggaggggctcggcagcctc
cacaccaggcaccactgccagattcccgtgcccgaccccgcgacccacggccaatacatc
gtctctgttcagccaaggaggacagagaaacacataaagagctcagtgaacatccagatg
gcccctccatccctcaacgtgaccaaggatggagacagctacagcctgcgctgggaaacg
atgaaaatgcgatacgaacacatagaccacacatttgagatccagtacaggaaagacacg
gccacgtggaaggacagcaagaccgagaccctccagaacgcccacagcatggccctgcca
gccctggagccctccaccaggtactgggccagggtgagggtcaggacctcccgcaccggc
tacaacgggatctggagcgagtggagtgaggcgcgctcctgggacaccgagtcggtgctg
cctatgtgggtgctggccctcgtcgtgatcttcctcaccatcgctgtgctcctggccctc
cgcttctgtggcatctacgggtacaggctgcgcagaaagtgggaggagaagatccccaac
cccagcaagagccacctgttccagaacgggagcgcagagctttggcccccaggcagcatg
tcggccttcaccagcgggagtcccccacaccaggggccgtggggcagccgcttccctgag
ctggagggggtgttccctgtaggattcggggacagcgaggtgtcacctctcaccatagag
gaccccaagcatgtctgtgatccaccgtctgggtctgacacgactccagctgcctcagat
ctacccacagagcagccccccagcccccagccaggcccgcctgccgcctcccacacacct
gagaaacaggcttccagctttgacttcaatgggccctacctggggccgccccacagccgc
tccctgcctgacatcctgggccagccggagcccccacaggagggtgggagccagaagtcc
ccaccaccggggtccctggagtacctgtgtctgcctgctggggggcaggtgcaactggtc
cctctggcccaggcgttgggaccgggacaggccgtggaagtggagaggaggccgagccag
ggggctgcagggatcccctccctggagtccgggggaggccctgcccctcctgctcttggg
ccaagggtgggaggacaggaccaaaaggacagccctgtggctatacccatgagctctggg
gacactgaggaccctggagtggcctctggttatgtctcctctgcagacctggtattcacc
ccacactcaggggcctcgtctgtctccctagttccctctctgggcctcccctcagaccag
acccccagcttatgtcctgggctggccagtggaccccctggagccccaggccctgtgaag
tcagggtttgagggctatgtggagctccctccaattgagggccggttccccaggtcacca
aggaacaatcctgtcccccctgaggccaaaagccctgtcctgaacccaggggaacgccgg
gcagatgtgtccccaacatctccacagcccgagggcctccttgtcctgcagcaagtgggc
gactattgcttcctccccggcctggggcccggccctctctcgctccggagtaaaccttct
tccccgggaccctgtcctgagatcagggacccagaccaggcttttcaagtcaagaagccc
ccaggccaggctgtgccccaggtgcccgtcattcagctcttcaaagccctgaagcagcag
gactacctgtctctgcccccttgggagatcaacaagcctggggaggtgtgttga

KEGG   Pan paniscus (bonobo): 100988791
Entry
100988791         CDS       T02283                                 

Gene name
IL5RA
Definition
(RefSeq) interleukin 5 receptor subunit alpha
  KO
K05067  interleukin 5 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100988791 (IL5RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100988791 (IL5RA)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100988791 (IL5RA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100988791 (IL5RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100988791 (IL5RA)
   04090 CD molecules [BR:pps04090]
    100988791 (IL5RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL3 receptor family
   100988791 (IL5RA)
CD molecules [BR:pps04090]
 Proteins
  100988791 (IL5RA)
SSDB
Motif
Pfam: IL6Ra-bind Tissue_fac Il13Ra_Ig
Other DBs
NCBI-GeneID: 100988791
NCBI-ProteinID: XP_003831278
UniProt: A0A2R9CM51
Position
3
AA seq 420 aa
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQSDHSLLASSWVSAELHA
PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIKPFDQLFALHAIDQIN
PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
LSKHDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFLIVIMATICFILLILSL
ICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKIGVETLEDSVF
NT seq 1263 nt   +upstreamnt  +downstreamnt
atgatcatcgtggcgcatgtattactcattcttttgggggccactgagatactgcaagct
gacttacttcctgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagtt
actggtttggctcaagttcttttacaatggaaaccaaatcctgatcaagagcaaaggaat
gttaatctagaatatcaagtgaaaataaacgctccaaaagaagatgactatgaaaccaga
atcactgaaagcaaatgtgtaaccatcctccacaaaggcttttcagcaagtgtgcggacc
atcctgcagagcgaccactcactactggccagcagctgggtttctgctgaacttcatgcc
ccaccagggtctcctggaacctcaattgtgaatttaacttgcaccacaaacactacagaa
gataattattcacgtttaaggtcataccaagtttcccttcactgcacctggcttgttggc
acagatgcccctgaggacacgcagtattttctctactataggtatggctcttggactgaa
gaatgccaggaatacagcaaagacacactggggagaaatatcgcatgctggtttcccagg
actttcatcctcagcaaagggcgtgactggcttgcggtgcttgttaacggctccagcaag
cactctgccatcaagccctttgatcagctgtttgcccttcacgccattgatcaaataaat
cctccactgaatgtcacagcagagattgaaggaactcgtctctctatccaatgggagaaa
ccagtgtctgcctttccaatccattgctttgattatgaagtaaaaatacacaatacaagg
aatggatatttgcagatagaaaaattgatgaccaatgcattcatctcaataattgatgat
ctttctaagcacgatgttcaagtgagagcagcagtgagctccatgtgcagagaggcaggg
ctctggagtgagtggagccaacctatttatgtgggaaatgatgaacacaagcccttgaga
gagtggtttctcattgtgattatggcaaccatctgcttcatcttgttaattctctcgctt
atctgtaaaatatgtcatttatggatcaagttgtttccaccaattccagcaccaaaaagt
aatatcaaagatctctttgtaaccactaactatgagaaagctgggtccagtgagacggaa
attgaagtcatctgttatatagagaagattggagttgagaccctggaggattctgtgttt
tga

KEGG   Pan paniscus (bonobo): 100988947
Entry
100988947         CDS       T02283                                 

Gene name
IFNGR2
Definition
(RefSeq) interferon gamma receptor 2
  KO
K05133  interferon gamma receptor 2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04066  HIF-1 signaling pathway
pps04217  Necroptosis
pps04380  Osteoclast differentiation
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05152  Tuberculosis
pps05164  Influenza A
pps05168  Herpes simplex virus 1 infection
pps05200  Pathways in cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100988947 (IFNGR2)
   04066 HIF-1 signaling pathway
    100988947 (IFNGR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100988947 (IFNGR2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100988947 (IFNGR2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100988947 (IFNGR2)
   04658 Th1 and Th2 cell differentiation
    100988947 (IFNGR2)
   04659 Th17 cell differentiation
    100988947 (IFNGR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100988947 (IFNGR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100988947 (IFNGR2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100988947 (IFNGR2)
  09172 Infectious disease: viral
   05164 Influenza A
    100988947 (IFNGR2)
   05168 Herpes simplex virus 1 infection
    100988947 (IFNGR2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100988947 (IFNGR2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100988947 (IFNGR2)
   05140 Leishmaniasis
    100988947 (IFNGR2)
   05142 Chagas disease
    100988947 (IFNGR2)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100988947 (IFNGR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100988947 (IFNGR2)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IFN receptor family
   100988947 (IFNGR2)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind fn3
Other DBs
NCBI-GeneID: 100988947
NCBI-ProteinID: XP_014198643
Position
21
AA seq 338 aa
MSTPSSSRVREPGNVLPDVQKGLCRYPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTR
PVVYRVQFKYTDSKWFMADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAEL
GALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHY
WEKGGIQQVKGPFRSNSISLDNLKPFRAYCLQVQAQLLWNKSNIFRVGHLSNISCYETMA
DASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDPT
QPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
NT seq 1017 nt   +upstreamnt  +downstreamnt
atgtccacgccctcatcctcaagagtccgtgaacctgggaatgtgctgcctgacgtacaa
aagggactttgcagataccctctttcccagctgcccgctcctcagcacccgaagattcgc
ctgtacaacgcagagcaggtcctgagttgggagccagtggccctgagcaatagcacgagg
cctgttgtctaccgagtgcagtttaaatacaccgacagtaaatggttcatggccgacatc
atgtccataggggtgaattgtacacagatcacagcaacagagtgtgacttcactgctgcc
agtccctcagcaggcttcccaatggatttcaatgtcactctacgccttcgagctgagctg
ggagcactccattctgcctgggtgacaatgccttggtttcaacactatcggaatgtgact
gtcgggcctccagaaaacattgaggtgaccccaggagaaggctccctcatcatcaggttc
tcctctccctttgacatcgctgatacctccacggcctttttttgttattatgtccattac
tgggaaaaaggaggaatccaacaggtcaaaggccctttcagaagcaactccatttcattg
gataacttaaaacccttcagagcgtactgtttacaagtccaggcacaactgctttggaac
aaaagtaacatctttagagtcgggcatttaagcaacatatcttgctacgaaacaatggca
gatgcctccactgagcttcagcaagtcatcctgatctccgtgggaacattttcgttgctg
tcggtgctggcaggagcctgtttcttcctggtcctgaaatacagaggcctgattaaatac
tggtttcacactccaccaagcatcccattacagatagaagagtatttaaaggacccaact
cagcccatcttagaggccttggacaaggacagctcaccaaaggatgacgtctgggactct
gtgtccattatctcgtttccggaaaaggagcaagaagatgttctccaaacgctttga

KEGG   Pan paniscus (bonobo): 100989661
Entry
100989661         CDS       T02283                                 

Gene name
IL22RA1
Definition
(RefSeq) interleukin 22 receptor subunit alpha 1
  KO
K05138  interleukin 22 receptor alpha 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100989661 (IL22RA1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100989661 (IL22RA1)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100989661 (IL22RA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100989661 (IL22RA1)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL10/28 receptor family
   100989661 (IL22RA1)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind
Other DBs
NCBI-GeneID: 100989661
NCBI-ProteinID: XP_003810814
UniProt: A0A2R9B5I5
Position
1
AA seq 574 aa
MRTLLTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTY
GERDWVAKKGCQQITRKSCNLTVETGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTT
LKPPDVTCIPKVRSIQMIVHPTPTPIRAGDGHRLTLEDIFHDLFYHLELQVNRTYQMHLG
GKQREYEFFGLTPDTEFLGTIMICVPTWSKESAPYMCRVKTLPDRTWTYSFSGAFLFSMG
FLVAVLCYLSYRYVTKPPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQ
YSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVG
PPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLS
SPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNV
LHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGSSPWGLLESLVCPK
DEAKSPAPETSDLEQPTELDSLFRGLALTVQWES
NT seq 1725 nt   +upstreamnt  +downstreamnt
atgaggacgctgctgaccatcttgactgtgggatccctggctgctcacgcccctgaggac
ccctcggatctgctccagcacgtgaaattccagtccagcaactttgaaaacatcctgacg
tgggacagcgggccggagggcaccccagacacggtctacagcatcgagtataagacgtac
ggagagagggactgggtggcaaagaagggctgtcagcagatcacccggaagtcctgcaac
ctgacggtggagacgggcaacctcacggagctctactatgccagggtcaccgctgtcagt
gcgggaggccggtcagccaccaagatgactgacaggttcagctctctgcagcacactacc
ctcaagccacctgatgtgacctgtatccccaaagtgagatcgattcagatgattgttcat
cctacccccacgcccatccgtgcaggggacggccaccggctaaccctggaagacatcttc
catgacctgttctaccacttagagctccaggtcaaccgcacctaccaaatgcaccttgga
gggaagcagagagaatatgagttcttcggcctgacccctgacacagagttccttggcacc
atcatgatttgcgttcccacctggtccaaggagagtgccccctacatgtgccgagtgaag
acactgccagaccggacgtggacctactccttctccggagccttcctgttctccatgggc
ttcctcgtcgcagtgctctgctacctgagctacagatatgtcaccaagccgcctgcacct
cccaactccctgaacgtccagcgagtcctgactttccagccgctgcgcttcatccaggag
cacgtcctgatccctgtctttgacctcagcggccccagcagtctggcccagcctgtccag
tactcccagatcagggtgtctggacccagggagcccgcaggagctccacagcggcacagc
ctgtccgagatcacctacttagggcagccagacatctccatcctccagccctccaacgtg
ccacctccccagatcctctccccactgtcctatgccccaaacgctgcccctgaggtcggg
cccccatcctatgcacctcaggtgacccccgaagctcaattcccattctacgcgccacag
gccatctctaaggtccagccttcctcctatgcccctcaagccactccggacagctggcct
ccctcctatggggtatgcatggaaggttctggcaaagactcccccactgggacactttct
agtcctaaacaccttaggcctaaaggtcagcttcagaaagagccaccagctggaagctgc
atgttaggtggcctttctctgcaggaggtgacctccttggctatggaggaatcccaagaa
gcaaaatcattgcaccagcccctggggatttgcacagacagaacatctgacccaaatgtg
ctacacagtggggaggaagggacaccacagtacctaaagggccagctcccccttctctcc
tcagtccagatcgagggccaccccatgtccctccctttgcaacctccttcccgtccatgt
tccccctcggaccaaggttcaagtccctggggcctgctggagtcccttgtgtgtcccaag
gatgaagccaagagcccagcccctgagacctcagacctggagcagcctacagaactggat
tctcttttcagaggcctggccctgactgtgcagtgggagtcctga

KEGG   Pan paniscus (bonobo): 100990004
Entry
100990004         CDS       T02283                                 

Gene name
IFNLR1, IL28RA
Definition
(RefSeq) interferon lambda receptor 1
  KO
K05140  interferon lambda receptor 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100990004 (IFNLR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100990004 (IFNLR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100990004 (IFNLR1)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL10/28 receptor family
   100990004 (IFNLR1)
SSDB
Motif
Pfam: Tissue_fac
Other DBs
NCBI-GeneID: 100990004
NCBI-ProteinID: XP_003810815
UniProt: A0A2R9BUW1
Position
1
AA seq 519 aa
MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
SSPTRRRWRKVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSSSSKSPWVESEYLDYL
FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLL
VIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVAAFQPSRPESVNDLFLCPQKELTR
GVRPTPRVRAPATQQAGWKKDLAEDEEEEEEDTEDGVSFQPYIEPPSFLGQEHQAPGHSE
AGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQGPGGDGH
QESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTFCWESSPE
EEEEARESEIEDSDAGSWGAESTHRTEDRGRTLGHYMAR
NT seq 1560 nt   +upstreamnt  +downstreamnt
atggcggggcccgagcgctggggccccctgctcctgtgcctgctgcaggccgctccaggg
aggccccgtctggcccctccccagaatgtgacgctgctctcccagaacttcagcgtgtac
ctgacatggctcccagggcttggcaacccccaggatgtgacctattttgtggcctatcag
agctctcccacccgtagacggtggcgcaaagtggaagagtgtgcaggaaccaaggagctg
ctatgttctatgatgtgcctgaagaaacaggacctgtacaacaagttcaagggacgtgtg
cggacggtttcttccagctccaagtccccctgggtggagtccgaatacctggattacctt
tttgaagtggagccggccccacctgtcctggtgctcacccagacggaggagatcctgagt
gccaatgccacgtaccagctgcccccctgcatgcccccactggatctgaagtatgaggtg
gcattctggaaggagggggccggaaacaagaccctatttccagtcactccccatggccag
ccagtccagatcactcttcagccagctgccagcgaacaccactgcctcagtgccagaacc
atctacacgttcagtgtcccgaaatacagcaagttctctaagcccacctgcttcttgctg
gaggtcccagaagccaactgggctttcctggtgctgccatcgcttctgatactgctgtta
gtaattgccgcagggggtgtgatctggaagaccctcatggggaacccctggtttcagcga
gcaaagatgccacgggccctggacttttctggacacacacaccctgtggcagcctttcag
cccagcagaccagagtccgtgaatgacttgttcctctgtccccaaaaggaactgaccaga
ggggtcaggccgacgcctcgagtcagggccccagccacccaacaggcaggatggaagaag
gaccttgcagaggacgaagaggaggaggaggaggacacagaagatggcgtcagcttccag
ccctacattgaaccaccttctttcctggggcaagagcaccaggctccagggcactcggag
gctggtggggtggactcagggaggcccagggctcctctggtcccaagcgaaggctcctct
gcttgggattcttcagacagaagctgggccagcactgtggactcctcctgggacagggct
gggtcctctggctatttggctgagaaggggccaggccaagggccgggtggggatgggcac
caagaatctctcccaccacctgaattctccaaggactcgggtttcctggaagagctccca
gaagataacctctcctcctgggccacctggggcaccttaccaccggagccgaatctggtc
cctgggggacccccagtttctcttcagacactgaccttctgctgggaaagcagccctgag
gaggaagaggaggcgagggaatcagaaattgaggacagcgatgcgggcagctggggggct
gagagcacccataggaccgaggacaggggccggacattggggcattacatggccaggtga

KEGG   Pan paniscus (bonobo): 100991889
Entry
100991889         CDS       T02283                                 

Gene name
IL9R
Definition
(RefSeq) interleukin 9 receptor
  KO
K05073  interleukin 9 receptor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100991889 (IL9R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100991889 (IL9R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100991889 (IL9R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100991889 (IL9R)
   04090 CD molecules [BR:pps04090]
    100991889 (IL9R)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100991889 (IL9R)
CD molecules [BR:pps04090]
 Proteins
  100991889 (IL9R)
SSDB
Other DBs
NCBI-GeneID: 100991889
NCBI-ProteinID: XP_003807374
UniProt: A0A2R9B547
Position
X
AA seq 342 aa
MPQTCDGTGQMHLGSNCCKNGQTLLQRTCHGVSCCGWWFQAAHSILGKGPSAQSLAGWTL
ESEALRRDMGTWLLACTCICTCVCLGVSVTGEGQGPRSRTFTCLTNNILRIDCHWSAPEL
GQGSSPWLLFTRLLATHISASCGAVSAPSCCHLRQCSCHLTISPSLSTTACLGGSRSAWW
TRSTCPGDTSNISSGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVT
WLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIP
PWGRPDNTLVAVSIFLLLTGLTYVLFKLSPRLGWGPTGPVCC
NT seq 1029 nt   +upstreamnt  +downstreamnt
atgcctcagacttgtgatgggactgggcagatgcatctgggaagtaactgctgcaagaac
ggacagacactgctgcagagaacttgccacggtgtttcatgctgcggctggtggttccag
gctgcacactccattctaggaaaggggccctcagcccagtcccttgcaggctggaccttg
gagagtgaggccctgaggcgagacatgggcacctggctcctggcctgcacctgcatctgc
acctgtgtctgcttgggagtctctgtcacaggggaaggacaagggccaaggtctagaacc
ttcacctgcctcaccaacaacattctcaggatcgattgccactggtctgccccagagctg
ggacagggctccagcccctggctcctcttcaccaggctcctggcgacacacataagtgca
tcttgcggggcagtgagtgcaccgtcgtgctgccacctgaggcagtgctcatgccatctg
acaatttcaccatcactttccaccactgcatgtctgggagggagcaggtcagcctggtgg
acccggagtacctgccccggagacacgagcaacatcagttctggccactgcatcctgacc
tggagcatcagtcctgccttggagccaatgaccacacttctcagctatgagctggccttc
aagaagcaggaagaggcctgggagcaggcccagcacagggatcacattgtcggggtgacc
tggcttatacttgaagcctttgagctggaccctggctttatccatgaggccaggctgcgt
gtccagatggccacactggaggatgatgtggtagaggaggagcgttatacaggccagtgg
agtgagtggagccagcctgtgtgcttccaggctccccagagacaaggccctctgatccca
ccctgggggcggccagacaacacccttgttgctgtgtccatctttctcctgctgactggc
ctgacctacgtcctgttcaagctgtcgcccagacttggatgggggcccacagggccggtg
tgctgttga

KEGG   Pan paniscus (bonobo): 100992032
Entry
100992032         CDS       T02283                                 

Gene name
IL6ST
Definition
(RefSeq) interleukin 6 signal transducer
  KO
K05060  interleukin 6 signal transducer
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04550  Signaling pathways regulating pluripotency of stem cells
pps04630  JAK-STAT signaling pathway
pps04659  Th17 cell differentiation
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100992032 (IL6ST)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100992032 (IL6ST)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100992032 (IL6ST)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100992032 (IL6ST)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100992032 (IL6ST)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100992032 (IL6ST)
   05203 Viral carcinogenesis
    100992032 (IL6ST)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100992032 (IL6ST)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100992032 (IL6ST)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100992032 (IL6ST)
   04090 CD molecules [BR:pps04090]
    100992032 (IL6ST)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100992032 (IL6ST)
CD molecules [BR:pps04090]
 Proteins
  100992032 (IL6ST)
SSDB
Motif
Pfam: fn3 Lep_receptor_Ig IL6Ra-bind EpoR_lig-bind Pur_ac_phosph_N fn3_2 Interfer-bind ObR_Ig DCP1
Other DBs
NCBI-GeneID: 100992032
NCBI-ProteinID: XP_003827430
Position
5
AA seq 918 aa
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
NANYIVWKTNHFTIPKEQYTVINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
ISGLPPEKPKNLSCIVNEGKKMRCEWDRGRETHLETNFTLKSEWATHKFADCKAKRDTPT
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYVATLTVRNLVGKSDAAVLTIPACD
FQATRPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIADWQQEDGTVHRT
YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD
QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG
KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN
TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS
ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV
NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG
MPKSYLPQTVRQGGYMPQ
NT seq 2757 nt   +upstreamnt  +downstreamnt
atgttgacgttgcagacttggttagtgcaagccttgtttattttcctcaccactgaatct
acaggtgaacttctagatccatgtggttatatcagtcctgaatctccagttgtacaactt
cattctaatttcactgcagtttgtgtgctaaaggaaaaatgtatggattattttcatgta
aatgctaattacattgtctggaaaacaaaccattttactattcctaaggagcaatatact
gtcataaacagaacagcatccagtgtcacctttacagatatagcttcattaaatattcag
ctcacttgcaacattcttacattcggacagcttgaacagaatgtttatggaatcacaata
atttcaggcttgcctccagaaaaacctaaaaatttgagttgcattgtgaacgaggggaag
aaaatgaggtgtgagtgggatcgtggaagggaaacacacttggagacaaacttcacttta
aaatctgaatgggcaacacacaagtttgctgattgcaaagcaaaacgtgacacccccacc
tcatgcactgttgattattctactgtgtattttgtcaacattgaagtctgggtagaagca
gagaatgcccttgggaaggttacatcagatcatatcaattttgatcctgtatataaagtg
aagcccaatccgccacataatttatcagtgatcaactcagaggaactgtctagtatctta
aaattgacatggaccaacccaagtattaagagtgttataatactaaaatataacattcaa
tataggaccaaagatgcctcaacttggagccagattcctcctgaagacacagcatccacc
cgatcttcattcactgtccaagaccttaaaccttttacagaatatgtgtttaggattcgc
tgtatgaaggaagatggtaagggatactggagtgactggagtgaagaagcaagtgggatc
acctatgaagatagaccatctaaagcaccaagtttctggtataaaatagatccatcccat
actcaaggctacagaactgtacaactcgtgtggaagacattgcctccttttgaagccaat
ggaaaaatcttggattatgaagtgactctcacaagatggaaatcacatttacaaaattac
acagttaatgctacaaaactgacagtaaatctcacaaatgatcgctatgtagcaacccta
acagtaagaaatcttgttggcaaatcagatgcagctgttttaactatccctgcctgtgac
tttcaagctactcgccctgtaatggatcttaaagcattccccaaagataacatgctttgg
gtggaatggactactccaagggaatctgtaaagaaatatatacttgagtggtgtgtgtta
tcagataaagcaccctgtatcgcagactggcaacaagaagatggtaccgtgcatcgcacc
tatttaagagggaacttagcagagagcaaatgttatttgataacagttactccagtatat
gctgacggaccaggaagccctgaatccataaaggcataccttaaacaagctccaccttcc
aaaggacctactgttcggacaaaaaaagtagggaaaaacgaagctgtcttagagtgggac
caacttcctgttgatgttcagaatggatttatcagaaattatactatattttatagaacc
atcattggaaatgaaactgctgtgaatgtggattcttcccacacagaatatacattgtcc
tctttgactagtgacacattgtacatggtacgaatggcagcatacacagatgaaggtggg
aaggatggtccagaattcacttttactaccccaaagtttgctcaaggagaaattgaagcc
atagtcgtgcctgtttgcttagcattcctattgacaactcttctgggagtgctgttctgc
tttaataagcgagacctaattaaaaaacacatctggcctaatgttccagatccttcaaag
agtcatattgcccagtggtcacctcacactcctccaaggcacaattttaattcaaaagat
caaatgtattcagatggcaatttcactgatgtaagtgttgtggaaatagaagcaaatgac
aaaaagccttttccagaagatctgaaatcattggacctgttcaaaaaggaaaaaattaat
actgaaggacacagcagtggtattggggggtcttcatgcatgtcatcttctaggccaagc
atttctagcagtgatgaaaatgaatcttcacaaaacacttcgagcactgtccagtattct
actgtggtacacagtggctacagacaccaagttccgtcagtccaagtcttctcaagatcc
gagtctacccagcccttgttagattcagaggagcggccagaagatctacaattagtagat
catgtagatggcggtgatggtattttgcccaggcaacagtacttcaaacagaactgcagt
cagcatgaatccagtccagatatttcacattttgaaaggtcaaagcaagtttcatcagtc
aatgaggaagattttgttagacttaaacagcagatttcagatcatatttcacaatcctgt
ggatctgggcaaatgaaaatgtttcaggaagtttctgcagcagatgcttttggtccaggt
actgagggacaagtagaaagatttgaaacagttggcatggaggctgcgactgatgaaggc
atgcctaaaagttacttaccacagactgtacggcaaggcggctacatgcctcagtga

KEGG   Pan paniscus (bonobo): 100992438
Entry
100992438         CDS       T02283                                 

Gene name
IL2RB
Definition
(RefSeq) interleukin 2 receptor subunit beta
  KO
K05069  interleukin 2 receptor beta
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04144  Endocytosis
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps05162  Measles
pps05166  Human T-cell leukemia virus 1 infection
pps05200  Pathways in cancer
pps05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100992438 (IL2RB)
   04151 PI3K-Akt signaling pathway
    100992438 (IL2RB)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100992438 (IL2RB)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100992438 (IL2RB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100992438 (IL2RB)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100992438 (IL2RB)
   04659 Th17 cell differentiation
    100992438 (IL2RB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100992438 (IL2RB)
   05202 Transcriptional misregulation in cancer
    100992438 (IL2RB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100992438 (IL2RB)
   05162 Measles
    100992438 (IL2RB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100992438 (IL2RB)
   04090 CD molecules [BR:pps04090]
    100992438 (IL2RB)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100992438 (IL2RB)
CD molecules [BR:pps04090]
 Proteins
  100992438 (IL2RB)
SSDB
Motif
Pfam: IL2RB_N1 Pur_ac_phosph_N IL6Ra-bind
Other DBs
NCBI-GeneID: 100992438
NCBI-ProteinID: XP_003821600
UniProt: A0A2R9B5X3
Position
22
AA seq 551 aa
MAAPALSWRLPLLILLLPLATPWASATVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQ
VHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTAVDIVTLRVLCREGVRWRVMA
IQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEE
APLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDT
IPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCHTPDPSKFFSQLSSEHGGDV
QKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFT
NQGYFFFHLPDALEIEACQVYFTYDPYTEEDADEGVAGAPTGSSPQPLQPLSGEDDTYCT
FPSRDGLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVP
DLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQ
ELQGQDPTHLV
NT seq 1656 nt   +upstreamnt  +downstreamnt
atggcggcccctgctctgtcctggcgtctgcccctcctcatcctcctcttgcccctggct
accccttgggcatctgcaacggtgaatggcacctcccagttcacatgcttctacaactcg
agagccaacatctcctgtgtctggagccaagatggggctctgcaggacacttcctgccaa
gtccatgcctggccggacagacggcggtggaaccaaacctgtgagctgctccccgtgagt
caagcatcctgggcctgcaacctgatcctcggagccccagattctcagaaactgaccgca
gtggacatcgtcaccctgagggtgctgtgccgtgagggggtgcgatggagggtgatggcc
atccaggacttcaagccctttgagaaccttcgcctgatggcccccatctccctccaagtt
gtccacgtggagacccacagatgcaacataagctgggaaatctcccaagcctctcactac
tttgaaaggcacctggagttcgaggcccggacgctgtccccaggccatacctgggaggag
gcccccctgctgactctcaagcagaagcaggaatggatctgcctggagacgctcacccca
gacacccagtatgagtttcaggtgcgggtcaagcctctgcaaggcgagttcacgacctgg
agcccctggagccagcccctggccttcaggacaaagcctgcagcccttgggaaggacacc
attccgtggctcggccacctcctcgtgggcctcagcggggcttttggcttcatcatctta
gtgtacttgctgatcaactgcaggaacaccgggccatggctgaagaaggtcctgaagtgt
cacaccccagacccctcgaagttcttttcccagctgagctcagagcatggaggagacgtc
cagaagtggctctcttcgcccttcccctcatcgtccttcagccctggcggcctggcacct
gagatctcgccactagaagtgctggagagggacaaggtgacgcagctgctcctgcagcag
gacaaggtgcctgagcccgcctccttaagcagcaaccactcgctgaccagctgcttcacc
aaccagggttacttcttcttccacctcccggatgccttggagatagaggcctgccaggtg
tactttacttacgacccctacacagaggaagacgctgatgagggtgtggccggggcaccc
acagggtcttccccccaacccctgcagcctctgtcaggggaggatgacacctactgcacc
ttcccctccagggatggcctgctgctcttctcccccagtctcctcggtggccccagcccc
ccaagcactgcccctgggggcagcggggccggtgaagagaggatgcccccttctttgcaa
gaaagagtccccagagactgggacccccagcccctggggcctcccaccccaggagtccca
gacctggtggattttcagccaccccctgagctggtgctgcgagaggctggggaggaggtc
cctgacgctggccccagggagggggtcagtttcccctggtccaggcctcctgggcagggg
gagttcagggcccttaatgctcgcctgcccctgaacactgatgcctacttgtccctccaa
gaactccagggtcaggacccaactcacttggtgtag

KEGG   Pan paniscus (bonobo): 100993433
Entry
100993433         CDS       T02283                                 

Gene name
IL20RA
Definition
(RefSeq) interleukin 20 receptor subunit alpha
  KO
K05136  interleukin 20 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100993433 (IL20RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100993433 (IL20RA)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100993433 (IL20RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100993433 (IL20RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL10/28 receptor family
   100993433 (IL20RA)
SSDB
Motif
Pfam: Interfer-bind Tissue_fac
Other DBs
NCBI-GeneID: 100993433
NCBI-ProteinID: XP_003827743
UniProt: A0A2R9A0L6
Position
6
AA seq 504 aa
MKNVLQWTPPEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYY
AKVKAIWGTKCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLP
VSMQQIYSNLKYNVSVLNTKSNRTWSQCVTNHTLVLTWLEPNTLYCVHVESFVPGPPRRA
QPSEKQCARTLKDQSSEFKAKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLI
LIYGNEFDKRFFVPAEKIVINFITLNISDDSKISHQDMSLLGKSSDVSSLNDPQPSGNLR
PPQEEEEVKHLGYASHLMEIFCDSEENTEGTYLTQQESLSRTIPPDKTVIEYEYDVRTTD
ICAGPEEQELSLQEEVSTQGTLLESQAALAVLGPQTLQYSYTPQLQDLDPLAQEHTDSEE
GPEEEPSTTLVDWDPQTGRLCIPSLSSFEQDSEGCEPSEGDGLGEEGLLSRLYEEPAPDR
PPGENETYLMQFMEEWGLYVQMEN
NT seq 1515 nt   +upstreamnt  +downstreamnt
atgaagaatgtcctacaatggactccaccagagggtcttcaaggagttaaagttacttac
actgtgcagtatttcatatatgggcaaaagaaatggctgaataaatcagaatgcagaaat
atcaatagaacctactgtgatctttctgctgaaacttctgactacgaacaccagtattat
gccaaagttaaggccatttggggaacaaagtgttccaaatgggctgaaagtggacggttc
tatccttttttagaaacacaaattggcccaccagaggtggcactgactacagatgagaag
tccatttctgttgtcctgacagctccagagaagtggaagagaaatccagaagaccttcct
gtttccatgcaacaaatatactccaatctgaagtataatgtgtctgtgttgaatactaaa
tcaaacagaacgtggtcccagtgtgtgaccaaccacacgctggtgctcacctggctggag
ccgaacactctttactgcgtgcacgtggagtcctttgtcccagggccccctcgccgtgct
cagccttctgagaagcagtgtgccaggactttgaaagatcaatcatcagagttcaaggct
aaaatcatcttctggtatgttttgcccgtatctattaccgtgtttcttttttctgtgatg
ggctattccatctaccgatatatccacgttggcaaagagaaacacccagcaaatttgatt
ttgatttatggaaatgaatttgacaaaagattctttgtgcctgctgaaaaaatcgtgatt
aactttatcaccctcaatatctcggatgattctaaaatttctcatcaggatatgagttta
ctgggaaaaagcagtgatgtatccagccttaatgatcctcagcccagcgggaacctgagg
ccccctcaggaggaagaggaggtgaaacatttagggtatgcttcgcatttgatggaaatt
ttttgtgactctgaagaaaacacggaaggtacttacctcacccagcaagagtccctcagc
agaacaatacccccggataaaacagtcattgaatatgaatatgatgtcagaaccactgac
atttgtgcggggcctgaagagcaggagctcagtttgcaggaggaggtgtccacgcaagga
acattattggagtcgcaggcagcgttggcagtcttgggcccgcaaacgttacagtactca
tacacccctcagctccaagacttagaccccctggcgcaggagcacacagactcggaggag
gggccagaggaagagccatcgacgaccctggtcgactgggatccccaaactggcaggctg
tgtattccttcgctgtccagcttcgagcaggattcagagggctgcgagccttctgagggg
gatggtctcggagaggagggccttctatctagactctatgaggagccggctccagacagg
ccaccaggagaaaatgaaacctatctcatgcaattcatggaggaatgggggttatatgtg
cagatggaaaactga

KEGG   Pan paniscus (bonobo): 100993771
Entry
100993771         CDS       T02283                                 

Gene name
IL22RA2
Definition
(RefSeq) interleukin 22 receptor subunit alpha 2
  KO
K05139  interleukin 22 receptor alpha 2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100993771 (IL22RA2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100993771 (IL22RA2)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL10/28 receptor family
   100993771 (IL22RA2)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind SCPU
Other DBs
NCBI-GeneID: 100993771
NCBI-ProteinID: XP_003827744
UniProt: A0A2R9CBZ0
Position
6
AA seq 231 aa
MMPKHCFLGFLISFVLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY
FVQYKIYGQRQWKNKEDCWGTQELFCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRF
TPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSL
EKEQKVYEGAHRVVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERCVEIP
NT seq 696 nt   +upstreamnt  +downstreamnt
atgatgcctaaacattgctttctaggcttcctcatcagtttcgtccttactggtgtagca
ggaactcagtcaacgcatgagtctctgaagcctcagagggtacaatttcagtcccgaaat
tttcacaacattttgcagtggcagcctgggagggcacttactggcaacagcagtgtctat
tttgtgcagtacaaaatatatggacagagacaatggaaaaataaagaagactgttggggt
actcaagaactcttttgtgaccttaccagtgaaacctcagacatacaggaaccttattac
ggtagggtgagggcggcgtcggctgggagctactcagaatggagcatgacgccgcggttc
actccctggtgggaaacaaaaatagatcctccagtcatgaatataacccaagtcaatgga
tctttgttggtaattctgcatgctccaaatttaccatatagataccaaaaggaaaaaaat
gtatctatagaagattactatgaactactataccgagtttttataattaacaattcacta
gaaaaggagcaaaaggtttatgaaggggctcacagagtggttgaaattgaagctctaaca
ccacactccagctactgtgtagtggctgaaatatatcagcccatgttagacagaagaagt
cagagaagtgaagagagatgtgtggaaattccatga

KEGG   Pan paniscus (bonobo): 100994342
Entry
100994342         CDS       T02283                                 

Gene name
IFNGR1
Definition
(RefSeq) interferon gamma receptor 1
  KO
K05132  interferon gamma receptor 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04066  HIF-1 signaling pathway
pps04217  Necroptosis
pps04380  Osteoclast differentiation
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05152  Tuberculosis
pps05164  Influenza A
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05200  Pathways in cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100994342 (IFNGR1)
   04066 HIF-1 signaling pathway
    100994342 (IFNGR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100994342 (IFNGR1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100994342 (IFNGR1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100994342 (IFNGR1)
   04658 Th1 and Th2 cell differentiation
    100994342 (IFNGR1)
   04659 Th17 cell differentiation
    100994342 (IFNGR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100994342 (IFNGR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100994342 (IFNGR1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100994342 (IFNGR1)
  09172 Infectious disease: viral
   05164 Influenza A
    100994342 (IFNGR1)
   05168 Herpes simplex virus 1 infection
    100994342 (IFNGR1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100994342 (IFNGR1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100994342 (IFNGR1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100994342 (IFNGR1)
   05140 Leishmaniasis
    100994342 (IFNGR1)
   05142 Chagas disease
    100994342 (IFNGR1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100994342 (IFNGR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100994342 (IFNGR1)
   04090 CD molecules [BR:pps04090]
    100994342 (IFNGR1)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IFN receptor family
   100994342 (IFNGR1)
CD molecules [BR:pps04090]
 Proteins
  100994342 (IFNGR1)
SSDB
Motif
Pfam: IFNGR1 Tissue_fac Interfer-bind
Other DBs
NCBI-GeneID: 100994342
NCBI-ProteinID: XP_003827746
UniProt: A0A2R9AUN0
Position
6
AA seq 489 aa
MALLFLLPLVMQGVSRAEMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFT
VEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFA
VCRDGKIGPPKLDIRKEEKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNG
SEIQYKILTQKEDDCDELQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFN
SSIKGSLWIPVVAALLLFLVLSLVFICFYIKKINPLKEKSIILPKSLISVVRSATLETKP
ESKYVSLITSYQPFSLEKEVVCEEPLSPATVPGMHTEDNPGKVEHTEELSSITEVVTTEE
NIPDVAPGSHLTPIERESSSPLSSNQSEPGSIALNSYHSRNCSESDHSRSGFDTDSSCLE
SHSSLSDSEFPPNNKGEIKTEGQELITVIKAPTSFGYDKPHVLVDLLVDDSGKESLIGYR
PTEDSKEFS
NT seq 1470 nt   +upstreamnt  +downstreamnt
atggctctcctctttctcctaccccttgtcatgcagggtgtgagcagggctgagatgggc
accgcggatctggggccgtcctcagtgcctacaccaactaatgttacaattgaatcctat
aacatgaaccctatcgtatattgggagtaccagatcatgccacaggtccctgtttttacc
gtagaggtaaagaactatggtgttaagaattcagaatggattgatgcctgcatcaatatt
tctcatcattattgtaatatttctgatcatgttggtgatccatcaaattctctttgggtc
agagttaaagccagggttggacaaaaagaatctgcctatgcaaagtcagaagaatttgct
gtatgccgagatggaaaaattggaccacctaaactggatatcagaaaggaggagaagcaa
atcatgattgacatatttcacccttcagtttttgtaaatggagacgagcaggaagtcgat
tatgatcccgaaactacctgttacattagggtgtacaatgtgtatgtgagaatgaacgga
agtgagatccagtataaaatactcacgcagaaggaagatgattgtgacgagcttcagtgc
cagttagcgattccagtatcctcactgaattctcagtactgtgtttcagcagaaggagtc
ttacatgtatggggtgttacaactgaaaagtcaaaagaagtttgtattaccattttcaat
agcagcataaaaggttctctttggattccagttgttgctgctttactactctttctagtg
cttagcctggtattcatctgtttttatattaagaagattaatccattgaaggaaaaaagc
ataatattacccaagtccttgatctctgtggtaagaagtgctactttagaaacaaaacct
gaatcaaaatatgtatcactcatcacgtcataccagccattttccttagaaaaggaggtg
gtctgtgaagagccgttgtctccagcaacagttccaggcatgcataccgaagacaatcca
ggaaaagtggaacatacagaagaactttctagtataacagaagtggtgactactgaagaa
aatattcctgacgtggccccgggcagccatctgactccaatagagagagagagttcttca
cctttaagtagtaaccagtctgaacctggcagcatcgctttaaactcgtatcactccaga
aattgttctgagagtgatcactccagaagtggttttgatactgattccagctgtctggaa
tcacatagctccttatctgactcagaatttcccccaaataataaaggtgaaataaaaaca
gaaggacaagagctcataaccgtaataaaagcccccacctcctttggttatgataaacca
catgtgctagtggatctacttgtggatgatagcggtaaagagtccttgattggttataga
ccaacagaagattccaaagaattttcatga

KEGG   Pan paniscus (bonobo): 100994584
Entry
100994584         CDS       T02283                                 

Gene name
IL15RA
Definition
(RefSeq) interleukin 15 receptor subunit alpha
  KO
K05074  interleukin 15 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04672  Intestinal immune network for IgA production
pps05166  Human T-cell leukemia virus 1 infection
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100994584 (IL15RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100994584 (IL15RA)
 09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    100994584 (IL15RA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100994584 (IL15RA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100994584 (IL15RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100994584 (IL15RA)
   04090 CD molecules [BR:pps04090]
    100994584 (IL15RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL2 receptor family
   100994584 (IL15RA)
CD molecules [BR:pps04090]
 Proteins
  100994584 (IL15RA)
SSDB
Motif
Pfam: RamS
Other DBs
NCBI-GeneID: 100994584
NCBI-ProteinID: XP_003827842
Position
10
AA seq 231 aa
MSVEHADIWVKSYSLYSRERYICNSGFKRKAGTSSLTECVLNKATNVAHWTTPSLKCIRD
PALVHQRPAPPSTVTTAGMTPQPESLSPSGKEPAASSPSSNTTAATTAAIVPGSQLMPSK
SPSTGTTEIGSHESSHGTPSQTTAKTWELTASASHQPPGVYPQGHSDTTVAISTSTVLLC
GLSAVSLLACYLKSRQTPPLASVEMEAMEALPVTGGTSSRDEDLENCSHHL
NT seq 696 nt   +upstreamnt  +downstreamnt
atgtccgtggaacacgcagacatctgggtcaagagctacagcttgtactccagggagcgg
tacatttgtaactctggtttcaagcgtaaagccggcacgtccagcctgacggagtgcgtg
ttgaacaaggccacgaatgtcgcccactggacaacccccagtctcaaatgcattagagac
cctgccctggttcaccaaaggccagcgccaccctccacagtaacgacggcagggatgacc
ccacagccagagagcctctccccttctggaaaagagcccgcagcttcatctcccagctca
aacaccacagcggccacaacagcagctattgtcccgggctcccagctgatgccttcaaaa
tcaccttccacaggaaccacagagataggcagtcatgagtcctcccacggcaccccctct
cagacaacagccaagacctgggaactcacagcatctgcctcccaccagccgccaggtgtg
tatccacagggccacagcgacaccactgtggctatctccacgtccactgtcctgctgtgt
gggctgagcgctgtgtctctcctggcatgctacctcaagtcaaggcaaactcccccgctg
gccagcgttgaaatggaagccatggaggctctgccggtgactggggggaccagcagcaga
gatgaagacttggaaaactgctctcaccacctatga

KEGG   Pan paniscus (bonobo): 100995446
Entry
100995446         CDS       T02283                                 

Gene name
IFNAR1
Definition
(RefSeq) interferon alpha and beta receptor subunit 1
  KO
K05130  interferon receptor 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04380  Osteoclast differentiation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100995446 (IFNAR1)
   04151 PI3K-Akt signaling pathway
    100995446 (IFNAR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100995446 (IFNAR1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100995446 (IFNAR1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100995446 (IFNAR1)
   04621 NOD-like receptor signaling pathway
    100995446 (IFNAR1)
   04650 Natural killer cell mediated cytotoxicity
    100995446 (IFNAR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100995446 (IFNAR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100995446 (IFNAR1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100995446 (IFNAR1)
   05160 Hepatitis C
    100995446 (IFNAR1)
   05171 Coronavirus disease - COVID-19
    100995446 (IFNAR1)
   05164 Influenza A
    100995446 (IFNAR1)
   05162 Measles
    100995446 (IFNAR1)
   05168 Herpes simplex virus 1 infection
    100995446 (IFNAR1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100995446 (IFNAR1)
   05169 Epstein-Barr virus infection
    100995446 (IFNAR1)
   05165 Human papillomavirus infection
    100995446 (IFNAR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100995446 (IFNAR1)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IFN receptor family
   100995446 (IFNAR1)
SSDB
Motif
Pfam: Interfer-bind Tissue_fac fn3 fn3_4
Other DBs
NCBI-GeneID: 100995446
NCBI-ProteinID: XP_003824035
UniProt: A0A2R8ZEG7
Position
21
AA seq 558 aa
MMVALLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT
FSFDYQKPGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF
TPFRKAQIGPPEVHLEAEDKAIVIHISPPGTKDSVMWALDGLSFTYSLVIWKNSSGVEER
IENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSV
QNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQ
KGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNT
PVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSS
VFSDVVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSNID
EYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYS
NEDESESKTSEELQQDFV
NT seq 1677 nt   +upstreamnt  +downstreamnt
atgatggtcgccctcctgggcgcgacgaccctagtgctcgtcgccgtggcgccatgggtg
ttgtccgcagccgcaggtggaaaaaatctaaaatctcctcaaaaagtagaggtcgacatc
atagatgacaactttatcctgaggtggaacaggagcgatgagtctgtcgggaatgtgact
ttttcattcgattatcaaaaacctgggatggataattggataaaattgtctgggtgtcag
aatattactagtaccaaatgcaacttttcttcactcaagctgaatgtttatgaagaaatt
aaattgcgtataagagcagaaaaagaaaacacttcttcatggtatgaggttgactcattt
acaccatttcgcaaagctcaaattggtcctccagaagtacatttagaagctgaagataag
gcaatagtgatacacatctctcctcctggaacaaaagatagtgttatgtgggctttggat
ggtttaagctttacatatagcttagttatctggaaaaactcttcaggtgtagaagaaagg
attgaaaatatttattccagacataaaatttataaactctcaccagagactacttattgt
ctaaaagttaaagcagcactacttacgtcatggaaaattggtgtctatagtccagtacat
tgtataaagaccacagttgaaaatgaactacctccaccagaaaatatagaagtcagtgtc
caaaatcagaactatgttcttaaatgggattatacatatgcaaacatgacctttcaagtt
cagtggctccacgcctttttaaaaaggaatcctggaaaccatttgtataaatggaaacaa
atacctgactgtgaaaatgtcaaaactacccagtgtgtctttcctcaaaacgttttccaa
aaaggaatttaccttctccgcgtacaagcatctgatggaaataacacatctttttggtct
gaagagataaagtttgatactgaaatacaagctttcctacttcctccagtctttaacatt
agatcccttagtgattcattccatatctatatcggtgctccaaaacagtctggaaacacg
cctgtgatccaggattatccactgatttatgaaattattttttgggaaaacacttcaaat
gctgagagaaaaattatcgagaaaaaaactgatgttacagttcctaatttgaaaccactg
actgtatattgtgtgaaagccagagcacacaccatggatgaaaagctgaataaaagcagt
gtttttagtgacgttgtgtgtgagaagacaaaaccaggaaatacctctaaaatttggctt
atagttggaatttgtattgcattatttgctctcccgtttgtcatttatgctgcgaaagtc
ttcttgagatgcatcaattatgtcttctttccatcacttaaaccttcttccaatatagat
gagtatttctctgaacagccattgaagaatcttctgctttcaacttctgaggaacaaatc
gaaaaatgttttataattgaaaatataagcacaattgctacagtagaagaaactaatcaa
actgatgaagatcataaaaaatacagttcccaaactagccaagattcaggaaattattct
aatgaagatgaaagcgaaagtaaaacaagtgaagaactacagcaggactttgtatga

KEGG   Pan paniscus (bonobo): 100995621
Entry
100995621         CDS       T02283                                 

Gene name
IL27RA
Definition
(RefSeq) interleukin 27 receptor subunit alpha
  KO
K19598  interleukin 27 receptor alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04659  Th17 cell differentiation
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100995621 (IL27RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100995621 (IL27RA)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100995621 (IL27RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100995621 (IL27RA)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL6/12 receptor family
   100995621 (IL27RA)
SSDB
Motif
Pfam: fn3
Other DBs
NCBI-GeneID: 100995621
NCBI-ProteinID: XP_003814905
UniProt: A0A2R9BJA2
Position
19
AA seq 636 aa
MRGGRGAPFWPWPLPKLALLTLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDL
GAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFV
NLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPMWPSHKVLICQFHYRRCQEAAWTLLE
PELKTIPLAPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSG
NLCGMPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPTGAEWARVSA
VNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWRPGPGEPLEHVVDWARDGD
PLEKLNWLRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASAPSVWGFREELAPLVGP
TLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSICMNVSGNTQSVTLPDL
PWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSG
RCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESS
QHPQATAPLDSGYEKHFLPTPEELGLLGPPRPQVLA
NT seq 1911 nt   +upstreamnt  +downstreamnt
atgcggggaggcaggggcgcccctttctggccgtggccgctgcccaagctggcgctgctg
actctgttgtgggtgcttttccagcggacgcgtccccagggcagcgccgggccactgcag
tgctacggagttggacccttgggcgacttgaactgctcgtgggagcctcttggggacctg
ggagccccctccgagttacacctccagagccaaaagtaccgttccaacaaaacccagact
gtggcagtggcagccggacggagctgggtggccattcctcgggaacagctcaccatgtct
gacaaactccttgtctggggcactaaggcaggccagcctctctggccccccgtcttcgtg
aacctagaaacccaaatgaagccaaacgccccccggctgggccctgacgtggacttttcc
gaggatgaccccctggaggccactgtccattgggccccacctatgtggccgtctcataaa
gttctgatctgccagttccactaccgaagatgtcaggaggcggcctggaccctgctggaa
ccggagctgaagaccatacccctggcccctgtcgagatccaagatttggagctagccact
ggctacaaagtgtatggccgctgccggatggagaaagaagaggatttgtggggcgagtgg
agccccattttgtccttccagacaccgccttctgctccaaaagatgtgtgggtatcaggg
aacctctgtgggatgcctggaggagaggaacctttgcttctatggaaggccccagggccc
tgtgtgcaggtgagctacaaagtctggttctgggttggaggtcgtgagctgagtccagaa
ggaattacctgctgctgctccctaattcccactggggcggagtgggccagggtgtccgct
gtcaacgccacaagctgggagcctctcaccaacctctctttggtctgcttggattcagcc
tctgccccccgtagcgtggcagtcagcagcatcgctgggagcacggagctactggtgacc
tggcgaccggggcctggggagccactggagcatgtagtggactgggctcgagatggggac
cccctggagaaactcaactggctccggcttccccctgggaacctcagtgctctgttacca
gggaatttcactgtcggggtcccctatcgaatcactgtgaccgcagtctctgcttcaggc
ttggcctctgcaccctccgtctgggggttcagggaggaattagcacccctagtggggcca
acgctttggcgactccaagatgcccctccagggacccccgccatagcgtggggagaggtc
ccaaggcaccagcttcgaggccacctcacccactacaccttgtgtgcacagagtggaacc
agcccctccatctgcatgaatgtgagtggcaacacacagagtgtcaccctgcctgatctt
ccttggggtccctgtgagctgtgggtgacagcatctaccatcgctggacagggccctcct
ggtcccatcctccggcttcatctaccagataacaccctgaggtggaaagttctgccgggc
atcctattcttgtggggcttgttcctgttggggtgtggcctgagcctggccacctctgga
aggtgctaccacctaaggcacaaagtgctgccccgctgggtctgggagaaagttcctgat
cctgccaacagcagttcaggccagccccacatggagcaagtacctgaggcccagcccctt
ggggacttgcccatcctggaagtggaggagatggagccgccgccggttatggagtcctcc
cagcacccccaggccaccgccccgcttgactctgggtatgagaagcacttcctgcccaca
cctgaggagctgggccttctggggccccccaggccacaggttctggcctga

KEGG   Pan paniscus (bonobo): 100995792
Entry
100995792         CDS       T02283                                 

Gene name
IFNAR2
Definition
(RefSeq) interferon alpha and beta receptor subunit 2
  KO
K05131  interferon receptor 2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04380  Osteoclast differentiation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05160  Hepatitis C
pps05162  Measles
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100995792 (IFNAR2)
   04151 PI3K-Akt signaling pathway
    100995792 (IFNAR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100995792 (IFNAR2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100995792 (IFNAR2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100995792 (IFNAR2)
   04621 NOD-like receptor signaling pathway
    100995792 (IFNAR2)
   04650 Natural killer cell mediated cytotoxicity
    100995792 (IFNAR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100995792 (IFNAR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100995792 (IFNAR2)
  09172 Infectious disease: viral
   05160 Hepatitis C
    100995792 (IFNAR2)
   05171 Coronavirus disease - COVID-19
    100995792 (IFNAR2)
   05164 Influenza A
    100995792 (IFNAR2)
   05162 Measles
    100995792 (IFNAR2)
   05168 Herpes simplex virus 1 infection
    100995792 (IFNAR2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100995792 (IFNAR2)
   05169 Epstein-Barr virus infection
    100995792 (IFNAR2)
   05165 Human papillomavirus infection
    100995792 (IFNAR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100995792 (IFNAR2)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IFN receptor family
   100995792 (IFNAR2)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind
Other DBs
NCBI-GeneID: 100995792
NCBI-ProteinID: XP_014198678
UniProt: A0A2R9B318
Position
21
AA seq 516 aa
MLLSQNAFIVRSLNLVLMVYISLVFGISHDSPDYTDESCTFKISLRNFRSILSWELKNHS
IVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTILEGFSGNTTLF
SCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKK
HKPEIKGNLSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAE
SAKIGGIITVFLIALVLTSTIVTLKWIGYICLRNSLPKVLNFHNFLAWPFPNLPPLEAMD
MVEVIYINRKKKVWDYNYDDESDSDTEAAHRTSGGGYTMHGLTVRPLGQASATSTESQLI
DPESEEEPDLPEVDVELPTMPKDSPQQLELLSGPCERRKSPLQDPFPEEDYSSTEGSGGR
ITFNVDLNSVFLRVLDDEDSDDLEEAPLMLSSHLEEMVDPEDPDNVQSNHLLASGEGTQP
TFPSPSSEGLWSEDAPSDQSDTSESDVDLGDGYIMR
NT seq 1551 nt   +upstreamnt  +downstreamnt
atgcttttgagccagaatgccttcatcgtcagatcacttaatttggttctcatggtgtat
atcagcctcgtgtttggtatttcacatgattcgcctgattacacagatgaatcttgcact
ttcaagatatcattgcgaaatttccggtccatcttatcatgggaattaaaaaaccactcc
attgtaccaactcactatacattgctgtatacaatcatgagtaaaccagaagatttgaag
gtggttaagaactgtgcaaataccacaagatcattttgtgacctcacagatgagtggaga
agcacacacgaggcctatgtcaccatcctagaaggattcagcgggaacacaacgttgttc
agttgctcacacaatttctggctggccatagacatgtcttttgaaccaccagagtttgag
attgttggttttaccaaccacattaatgtgatggtgaaatttccatctattgttgaggaa
gaattacagtttgatttatctctcgtcattgaagaacagtcagagggaattgttaagaag
cataaacccgaaataaaagggaacctgagtggaaatttcacctatatcattgacaagtta
attccaaacacgaactactgtgtatctgtttatttagagcacagtgatgagcaagcagta
ataaagtctcccttaaaatgcaccctccttccacctggccaggaatcagaatcagcagaa
tctgccaaaataggaggaataattactgtgtttttgatagcattggtcttgacaagcacc
atagtgacactgaaatggattggttatatatgcttaagaaacagcctccccaaagtcttg
aattttcataactttttagcctggccatttcctaacctgccaccgttggaagccatggat
atggtggaggtcatttacatcaacagaaagaagaaagtgtgggattataattatgatgat
gaaagtgatagcgatactgaggcagcgcacaggacaagtggcggtggctataccatgcat
ggactgactgtcaggcctctgggtcaggcctctgccacctctacagaatcccagttgata
gacccggagtccgaggaggagcctgacctgcctgaggttgatgtggagctccccacgatg
ccaaaggacagccctcagcagttggaactcttgagtgggccctgtgagaggagaaagagt
ccactccaggacccttttcccgaagaggactacagctccacggaggggtctgggggcaga
attaccttcaatgtggatttaaactctgtgtttttgagagttcttgatgacgaggacagt
gacgacttagaagaagcccctctgatgctatcgtctcatctggaagagatggttgaccca
gaggatcctgataatgtgcaatcaaaccatttgctggccagcggggaagggacacagcca
acctttcccagcccctcttcagagggcctgtggtccgaagatgctccatctgatcaaagt
gacacttctgagtcagatgttgaccttggggatggttatataatgagatga

KEGG   Pan paniscus (bonobo): 100996136
Entry
100996136         CDS       T02283                                 

Gene name
IL10RB
Definition
(RefSeq) interleukin 10 receptor subunit beta
  KO
K05135  interleukin 10 receptor beta
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
pps05145  Toxoplasmosis
pps05152  Tuberculosis
pps05163  Human cytomegalovirus infection
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100996136 (IL10RB)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100996136 (IL10RB)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100996136 (IL10RB)
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100996136 (IL10RB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100996136 (IL10RB)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100996136 (IL10RB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:pps04050]
    100996136 (IL10RB)
   04090 CD molecules [BR:pps04090]
    100996136 (IL10RB)
Cytokine receptors [BR:pps04050]
 Interleukin receptor families
  IL10/28 receptor family
   100996136 (IL10RB)
CD molecules [BR:pps04090]
 Proteins
  100996136 (IL10RB)
SSDB
Motif
Pfam: Interfer-bind Tissue_fac fn3 MP_p6
Other DBs
NCBI-GeneID: 100996136
NCBI-ProteinID: XP_003824037
UniProt: A0A2R8ZBT2
Position
21
AA seq 325 aa
MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR
IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV
EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN
LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLS
CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE
DSESGKQNPGDSCSLGTPPGQGPQS
NT seq 978 nt   +upstreamnt  +downstreamnt
atggcgtggagccttgggagctggttgggtggctgcctgctggtgtcagcattgggaatg
gtaccacctcccgaaaatgtcagaatgaattctgttaatttcaagaacattctacagtgg
gagtcacctgcttttgccaaagggaacctgactttcacagctcagtacctaagttatagg
atattccaagataaatgcatgaatactaccttgacggaatgtgatttctcaagtctttcc
aagtatggtgaccacaccttgagagtcagggctgaatttgcagatgagcattcagactgg
gtaaacatcaccttctgtcctgtggatgacaccattattggaccccctggaatgcaagta
gaagtacttgctgattctttacatatgcgtttcttagcccctaaaattgagaatgaatac
gaaacttggactatgaagaatgtgtataactcatggacttataatgtgcaatactggaaa
aacggtactgatgaaaagtttcaaattactccccagtatgactttgaggtcctcagaaac
ctggagccatggacaacttattgtgttcaagttcgagggtttcttcctgatcggaacaaa
gctggggaatggagtgagcctgtctgtgagcaaacaacccatgacgaaacggtcccctcc
tggatggtggccgtcatcctcatggcctcggtcttcatggtctgcctggcactcctcagc
tgcttcgccttgctgtggtgcgtttataagaagacaaagtacgccttctcccctaggaat
tctcttccacagcacctgaaagagtttttgggccatcctcatcataacacacttctgttt
ttctcctttccattgtcggatgagaatgatgttttcgacaagctaagtgtcattgcagaa
gactctgagagcggcaagcagaatcctggtgacagctgcagcctcgggaccccgcctggg
caggggccccaaagctag

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