KEGG   Panthera tigris altaica (Amur tiger): 102959656
Entry
102959656         CDS       T02988                                 
Symbol
EGF
Name
(RefSeq) epidermal growth factor
  KO
K04357  epidermal growth factor
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg01521  EGFR tyrosine kinase inhibitor resistance
ptg04010  MAPK signaling pathway
ptg04012  ErbB signaling pathway
ptg04014  Ras signaling pathway
ptg04015  Rap1 signaling pathway
ptg04020  Calcium signaling pathway
ptg04066  HIF-1 signaling pathway
ptg04068  FoxO signaling pathway
ptg04072  Phospholipase D signaling pathway
ptg04151  PI3K-Akt signaling pathway
ptg04510  Focal adhesion
ptg04540  Gap junction
ptg04630  JAK-STAT signaling pathway
ptg04810  Regulation of actin cytoskeleton
ptg05160  Hepatitis C
ptg05165  Human papillomavirus infection
ptg05200  Pathways in cancer
ptg05207  Chemical carcinogenesis - receptor activation
ptg05208  Chemical carcinogenesis - reactive oxygen species
ptg05210  Colorectal cancer
ptg05212  Pancreatic cancer
ptg05213  Endometrial cancer
ptg05214  Glioma
ptg05215  Prostate cancer
ptg05218  Melanoma
ptg05219  Bladder cancer
ptg05223  Non-small cell lung cancer
ptg05224  Breast cancer
ptg05226  Gastric cancer
ptg05231  Choline metabolism in cancer
ptg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102959656 (EGF)
   04012 ErbB signaling pathway
    102959656 (EGF)
   04014 Ras signaling pathway
    102959656 (EGF)
   04015 Rap1 signaling pathway
    102959656 (EGF)
   04630 JAK-STAT signaling pathway
    102959656 (EGF)
   04066 HIF-1 signaling pathway
    102959656 (EGF)
   04068 FoxO signaling pathway
    102959656 (EGF)
   04020 Calcium signaling pathway
    102959656 (EGF)
   04072 Phospholipase D signaling pathway
    102959656 (EGF)
   04151 PI3K-Akt signaling pathway
    102959656 (EGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102959656 (EGF)
   04540 Gap junction
    102959656 (EGF)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102959656 (EGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102959656 (EGF)
   05207 Chemical carcinogenesis - receptor activation
    102959656 (EGF)
   05208 Chemical carcinogenesis - reactive oxygen species
    102959656 (EGF)
   05231 Choline metabolism in cancer
    102959656 (EGF)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102959656 (EGF)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102959656 (EGF)
   05212 Pancreatic cancer
    102959656 (EGF)
   05226 Gastric cancer
    102959656 (EGF)
   05214 Glioma
    102959656 (EGF)
   05218 Melanoma
    102959656 (EGF)
   05219 Bladder cancer
    102959656 (EGF)
   05215 Prostate cancer
    102959656 (EGF)
   05213 Endometrial cancer
    102959656 (EGF)
   05224 Breast cancer
    102959656 (EGF)
   05223 Non-small cell lung cancer
    102959656 (EGF)
  09172 Infectious disease: viral
   05160 Hepatitis C
    102959656 (EGF)
   05165 Human papillomavirus infection
    102959656 (EGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102959656 (EGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ptg04052]
    102959656 (EGF)
Cytokines and neuropeptides [BR:ptg04052]
 Cytokines
  Growth factors (RTK binding)
   102959656 (EGF)
SSDB
Motif
Pfam: Ldl_recept_b cEGF FXa_inhibition EGF_CA EGF EGF_3 DUF5050 Plasmod_Pvs28 Tr-sialidase_C PAP_PilO hEGF
Other DBs
NCBI-GeneID: 102959656
NCBI-ProteinID: XP_007098313
Position
Un
AA seq 1213 aa
MLLFLIILLPVVFKFSFVSLSVLQGWDCSEGSSSGKGNSTCVGPEPFLIFSHGGSIFRID
LDGTNYEQLVADAGVSVIMDFHYYKERLYWVDLERQLLQRVFLNGTRQETVCNIEKNVSG
MAINWINEELIWSNQQEGIITVTDMKGNNSRVLLSALKYPANVAIDPVERFIFWSSEVAG
SLHRADLNGVEVKILLETSERITAVSLDVLDKRLFWIQNSRDGSNSYICSCNYDGGSVHF
NKQLTQHSLFAMSLFGDRIFYSTWKKKTIWIANKHTGKDMVRINLNPSFVPSGGIKVVHP
LLQPKAESDAWAPGQKLCKLRKGNCTGSMCEQDSKSHLCTCAEGYTLSPDGKHCEDVNEC
AFWNHGCTLGCENIPGSYYCTCPVGFILLPDGKRCHQLISCPSNTSKCSHDCVLTSDGPI
CFCPEGSVLETDGKTCSGCSSPDNGGCSQLCLPLSPVSWECGCFPGYDLQLDKKSCAASG
PQPFLLFANSQDIRHVRFDGTDYGSLLSQQMGMVFALDHDPVENKIYFAHTALKWIERAN
MDGSQRERLIEEAVDVPEGLAIDWIDRKFYWTDRGKSLIEGSDLNGKHREIIIKEEVSQP
RGIAVHPMAKRLFWTDMGINPRIESSSLQGIGRRVIASSDLVWPSGITIDYLTDKLYWCD
AKQSVIEMANLDGSKRQRLAQNDVGHPFAIAVFEDHVWFSDWTMPSVIRVNKRTGKNRVR
LRGSMLKPSSLVIVHPLAKPGSDPCLHQNGGCEHICKERFGSAQCLCREGFVKAPDGKMC
LALNGHQIPPAVGSEADLSNQVTPLDVLSRNRGSEDNSTESQHMLVAEIMVSDNDDCGPI
RCGTWAQCVSEGENATCQCLKGFTGDGKLCSDINECGTSTTVCPPTSSKCINTEGGYVCQ
CSEGYRGDGIHCLDIDECQLGIHTCGENATCTNTEGNYTCMCAGTLSEPGQICPDSTPPS
VLMEDGRYSVRNSYQKCPPSYDGYCLYNGVCMYIEAVDRYACNCVFGYVGERCQHRDLKW
ELRHAGQGRQRQVTVVAVCVVALVLLLLLGLWGAHCYRTKKLPSKNLKNPYEESSREVSR
PTDSEAGMASCPQPWFVVIKEHQNLRNGSQSMALKDSEAADVSQFSSRETGSVQLPSRRN
EPQVYMGGEQGCCIPPSSDKGSGPHRMQWGFHLPSCEAQPIALGVEKSQSLLSANPILQQ
RASDLPHQKKLTQ
NT seq 3642 nt   +upstreamnt  +downstreamnt
atgctgctcttccttatcattctgttgccagtagtttttaaatttagttttgttagtctc
tcagtactgcaaggctgggactgttctgaaggctcttcctcaggaaaggggaattctact
tgtgtgggtcctgaacctttcttaattttctcccatggaggcagtatctttaggattgac
ctggacggaactaattatgagcagttggtggctgatgctggtgtatcagtgatcatggat
tttcattactataaggaaagactctattgggtagatctagaacggcaacttttgcaaaga
gtttttctgaatgggacaaggcaagagacagtatgcaatatagagaaaaatgtttcagga
atggcaataaattggataaatgaagaacttatttggtcaaatcaacaggaaggaatcatt
acagtaacagacatgaaaggaaacaattcccgtgttctcttaagcgccttaaaatatcct
gcaaatgtagcaattgatccagtagaaaggtttatattttggtcttcagaggtggctggc
agcctccacagagcagatctcaatggtgtggaagtgaagattctgttagagacgtcagaa
agaataaccgctgtgtcactggatgtgcttgataaacggcttttttggattcagaacagt
agagacggaagcaattcttatatttgttcctgtaattatgatggaggttctgtgcatttt
aacaaacagcttacgcagcacagtttgtttgcaatgtccctttttggtgatcgtatcttc
tattcaacatggaaaaagaagacaatttggatagctaacaaacacactgggaaggatatg
gttagaatcaacctcaatccatcatttgtaccatctggtggaatcaaagtagtgcatcca
cttttacagcccaaggcagagagtgatgcttgggcacctggtcagaaactctgcaagctg
aggaaaggtaactgcacaggcagcatgtgtgagcaagactctaagtcccatttgtgcacg
tgcgcggaggggtatactttaagcccagatggaaagcactgtgaagatgtcaatgaatgt
gccttttggaatcatggctgtactcttgggtgtgaaaacattcctggatcttattattgc
acatgccctgtaggatttattctgcttcctgatgggaaacggtgtcatcaattaatttcc
tgtccaagcaatacatctaaatgtagccatgactgtgttctgacatcagatggtcccata
tgtttctgtcctgaaggctcagtgcttgagacagatggaaaaacatgcagtggctgttca
tcacccgataatggtggatgtagccaactctgcctccctcttagcccagtatcctgggaa
tgtggttgctttcctgggtatgacctacaactggacaaaaaaagttgtgcagcatcagga
ccacagccatttttgctgtttgccaattctcaagatattcgacatgtgcgttttgatgga
acagattatggatccctgctcagccagcaaatgggaatggtttttgcccttgatcacgac
cctgtggaaaataagatatattttgcccatacagccctgaagtggatagagagagctaat
atggatggttctcagcgagaaaggcttattgaggaagcagtagatgtgccagaaggtctt
gccatagactggattgaccgtaaattctactggacagacagagggaaatctctcattgaa
gggagtgatttaaatggaaagcatcgtgaaataatcatcaaggaggaggtctctcagcca
cgaggaattgctgtccatccaatggccaagcgattattctggactgatatggggattaat
ccacgaattgaaagttcttcccttcaaggcattggccgacgggttatagctagttctgat
ctggtctggcccagtggaataacgattgattacttaactgacaaattgtattggtgtgat
gccaagcagtctgtgatcgaaatggccaatctggatggttcaaaacgccaaagacttgcc
cagaacgatgtaggtcacccttttgctatagctgtgtttgaggatcacgtgtggttctct
gattggactatgccatcggtaataagggtgaacaagaggactggcaaaaatagggtacgt
ctccgaggcagcatgctgaagccttcatcactggttatagttcatccattggcaaaacca
ggatcagatccctgcttacaccaaaatggaggctgtgaacatatttgcaaagagaggttt
ggatctgctcagtgtttgtgtcgtgaaggttttgtgaaagccccagatgggaaaatgtgt
ctggctctcaatggccatcagataccaccagcagtaggtagtgaagcagatctaagtaac
caagtaacaccactggatgtcttatccaggaatagaggatctgaagataacagtacagaa
tctcaacatatgctagtggctgagatcatggtgtcagataatgacgactgtggtcctata
agatgtggtacatgggctcagtgtgtttcagaaggagaaaatgccacatgtcagtgtttg
aaaggatttactggcgatggaaaactatgttctgatataaatgagtgtgggacaagcacc
accgtttgccctcccacctcctccaagtgcatcaacactgaaggcggctacgtttgccag
tgctcagaaggctaccggggagatgggattcactgtcttgatattgatgagtgccagttg
ggcatacacacctgtggggaaaatgccacctgtacaaatacagagggaaactacacctgc
atgtgtgccggcaccctgtctgaacctggacagatatgtcctgactctactcctccttct
gttctcatggaggatggccgctattctgtgagaaacagttaccagaaatgccccccatcc
tatgacgggtactgcctctataacggtgtgtgtatgtatattgaagcagtggacagatac
gcatgcaactgtgtttttggctatgttggggagcgatgtcagcaccgggacttgaaatgg
gaactgcgccacgctggccaagggagacagcggcaagtcactgtggtggccgtctgcgtg
gtggcgctcgtcttgctgctgctgctggggctgtggggggcgcactgctacagaactaag
aagctaccatcaaaaaatttgaagaatccttatgaagagtcgagcagagaagttagtagg
cctacagacagcgaggcagggatggcctcttgtccccaaccttggtttgtggttataaag
gaacaccaaaatctcaggaatggaagtcaatctatggccctcaaggacagtgaggcagca
gatgttagccagttttcctctcgggagacagggtcagtgcaactgccatcacggagaaat
gaaccccaggtgtacatgggcggagagcaaggctgctgcattccaccatccagtgataaa
ggctctggtccccacagaatgcagtggggttttcatctcccttcctgtgaggcacagccc
attgctctgggggttgagaagtcacaatctctcttgtcagcaaaccccatattgcaacaa
agggcctcagatctaccacaccaaaagaagctgactcagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (31)   
   KEGG PATHWAY (31)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (11)   
   Pfam (11)   
All databases (57)   

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