KEGG   Pan troglodytes (chimpanzee): 745937
Entry
745937            CDS       T01005                                 

Gene name
CYP11B2
Definition
(RefSeq) cytochrome P450 11B2, mitochondrial isoform X1
  KO
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00140  Steroid hormone biosynthesis
ptr01100  Metabolic pathways
ptr04925  Aldosterone synthesis and secretion
Module
ptr_M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    745937 (CYP11B2)
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    745937 (CYP11B2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ptr00199]
    745937 (CYP11B2)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     745937 (CYP11B2)
    1.14.15.5  corticosterone 18-monooxygenase
     745937 (CYP11B2)
Cytochrome P450 [BR:ptr00199]
 Cytochrome P450, animal type
  CYP11 family
   745937 (CYP11B2)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 745937
NCBI-ProteinID: XP_024201099
VGNC: 14630
Position
8
AA seq 503 aa
MALRAKAEVCVAAPWLSLQRARALGTRAPRAPRTVLPFEAMPQHPGNRWLRLLQIWREQG
YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPRRMILEPWVAYR
QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALRKKVLQNA
RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM
PRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELS
LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQALRQESLAAAASISEHPQKATT
ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRP
ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQED
IKMVYSFILRPGTSPLLTFRAIN
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggcactcagggcaaaggcagaggtgtgcgtggcagcgccctggctgtccctgcaaagg
gcacgggcactgggcactagagcccctcgggcccctaggacggtgctgccgtttgaagcc
atgccccagcatccaggcaacaggtggctgaggctgctgcagatctggagggagcagggt
tatgagcacctgcacctggagatgcaccagaccttccaggagctggggcccattttcagg
tacaacttgggaggaccacgcatggtgtgtgtgatgctgccggaggatgtggagaagctg
caacaggtggacagcctgcatccccgcaggatgatcctggagccctgggtggcctacaga
caacatcgtgggcacaaatgtggcgtgttcttgttgaatgggcctgaatggcgctttaac
cgattgcggctgaacccagatgtgctgtcacccaaggccgtgcagaggttcctcccgatg
gtggatgcagtggccagggacttctcccaggccctgaggaagaaggtgctacagaacgcc
cgggggagcctgaccctggacgtccagcccagcatcttccactacaccatagaagccagc
aacttagctctttttggagagcggctgggcctggttggccacagccccagttctgccagc
ctgaacttcctccatgccctggaggtcatgttcaaatccaccgtccagctcatgttcatg
cccaggagcctgtctcgctggatcagccccaaggtgtggaaggagcactttgaggcctgg
gactgcatcttccagtacggtgacaactgtatccagaaaatctaccaggaactggccttc
aaccgccctcaacactacacaggcatcgtggcagagctcctgttgaaggcggaactgtca
ctagaagccatcaaggccaactctatggaactcactgcagggagcgtggacacgacagca
tttcccttgctgatgacgctctttgagctggctcggaaccccgacgtgcagcaggccctg
cgccaggagagcctggccgccgcagccagcatcagtgaacatccccagaaggcaaccacc
gagctgcccttgctgcgggcggccctcaaggagaccttgaggctctaccctgtgggtctg
tttttggagcgagtggtgagctcagacttggtgcttcagaactaccacatcccagctggg
acattggtgcaggttttcctctactcgctgggtcgcaacgccgccttgttcccgaggcct
gagcggtataatccccagcgctggctagacatcaggggctccggcaggaacttccaccac
gtgccctttggctttggcatgcgccagtgcctcgggcggcgcctggcagaggcagagatg
ctgctgctgctgcaccacgtgctgaagcacttcctggtggagacactaacccaagaggac
ataaagatggtctacagcttcatattgaggcctggcacgtcccccctcctcactttcaga
gcaatcaactag

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