KEGG   REACTION: R03045
Entry
R03045                      Reaction                               
Name
3-hydroxypropionyl-CoA hydro-lyase
Definition
3-Hydroxypropionyl-CoA <=> Propenoyl-CoA + H2O
Equation
C05668 <=> C00894 + C00001
Reaction class
RC00834  C00894_C05668
Enzyme
4.2.1.17        4.2.1.116       4.2.1.-
Pathway
rn00410  beta-Alanine metabolism
rn00640  Propanoate metabolism
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00013  Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA
M00375  Hydroxypropionate-hydroxybutylate cycle
M00376  3-Hydroxypropionate bi-cycle
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17
     R03045  3-Hydroxypropionyl-CoA <=> Propenoyl-CoA + H2O
    4.2.1.116
     R03045  3-Hydroxypropionyl-CoA <=> Propenoyl-CoA + H2O
    4.2.1.-
     R03045  3-Hydroxypropionyl-CoA <=> Propenoyl-CoA + H2O
IUBMB reaction hierarchy [BR:br08202]
 4. Lyase reactions
  4.2.1.17
   R02685  (3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA
    R03045  3-Hydroxypropionyl-CoA <=> Propenoyl-CoA
Overall reaction [br08210.html]
 Carbon fixation
  R03045
Orthology
K01692  enoyl-CoA hydratase [EC:4.2.1.17]
K01782  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01825  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
K07511  enoyl-CoA hydratase [EC:4.2.1.17]
K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07515  enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K14469  acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase [EC:1.3.1.84 4.2.1.116 6.2.1.36]
K14729  multifunctional beta-oxidation protein [EC:4.2.1.- 1.1.1.-]
K15019  3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116]
Other DBs
RHEA: 26521

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