KEGG   Rattus norvegicus (rat): 171045
Entry
171045            CDS       T01003                                 
Symbol
Mmp3
Name
(RefSeq) stromelysin-1 preproprotein
  KO
K01394  matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04657  IL-17 signaling pathway
rno04668  TNF signaling pathway
rno05171  Coronavirus disease - COVID-19
rno05202  Transcriptional misregulation in cancer
rno05215  Prostate cancer
rno05323  Rheumatoid arthritis
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    171045 (Mmp3)
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    171045 (Mmp3)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    171045 (Mmp3)
  09162 Cancer: specific types
   05215 Prostate cancer
    171045 (Mmp3)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    171045 (Mmp3)
  09163 Immune disease
   05323 Rheumatoid arthritis
    171045 (Mmp3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    171045 (Mmp3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    171045 (Mmp3)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.17  stromelysin 1
     171045 (Mmp3)
Peptidases and inhibitors [BR:rno01002]
 Metallo peptidases
  Family M10
   171045 (Mmp3)
SSDB
Motif
Pfam: Peptidase_M10 Hemopexin PG_binding_1 Astacin DUF4953 Reprolysin_5 Reprolysin_3 Reprolysin_4 Peptidase_M66
Other DBs
NCBI-GeneID: 171045
NCBI-ProteinID: NP_598207
RGD: 621317
Ensembl: ENSRNOG00000032626
UniProt: A6JN31
Position
8:12925267..12938828
AA seq 475 aa
MKGLPVLLWLCTAVCSSYPLHGSEEDAGMEVLQKYLENYYGLEKDVKQFTKKKDSSPVVK
KIQEMQKFLGLKMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKNHISYRIVNYT
LDLPRESVDSAIERALKVWEEVTPLTFSRISEGEADIMISFAVEEHGDFIPFDGPGMVLA
HAYAPGPGINGDAHFDDDERWTDDVTGTNLFLVAAHELGHSLGLFHSANAEALMYPVYKS
STDLARFHLSQDDVDGIQSLYGPPTESPDVLVVPTKSNSLDPETLPMCSSALSFDAVSTL
RGEVLFFKDRHFWRKSLRTPEPGFYLISSFWPSLPSNMDAAYEVTNRDTVFILKGNQIWA
IRGHEELAGYPKSIHTLGLPETVQKIDAAISLKDQKKTYFFVEDKFWRFDEKKQSMDPGF
PRKIAENFPGIGTKVDAVFEAFGFLYFFSGSSQLEFDPNAGKVTHILKSNSWFNC
NT seq 1428 nt   +upstreamnt  +downstreamnt
atgaaagggctcccagtcctgctgtggctgtgtacggctgtgtgctcatcctacccattg
catggcagtgaagaagatgctggcatggaggttctgcagaaatacctagaaaactactat
ggtcttgaaaaggatgtgaagcagtttactaagaaaaaggacagtagccctgttgtcaaa
aaaattcaagaaatgcagaagttccttgggctgaagatgacagggaagctggactcgaac
actatggagctgatgcacaagccccggtgtggtgttcccgacgtcggtggcttcagtacc
tttccaggttcacccaaatggaggaaaaaccacatctcctacaggattgtgaattataca
ctggatttaccaagagagagtgtggattctgccattgagagagctttgaaggtctgggag
gaggtgaccccactcacattctccaggatctctgaaggagaggctgacataatgatctcc
tttgcagttgaagaacatggagactttatcccttttgatgggcctggaatggtcttggct
catgcctatgcccctggaccagggattaatggagatgctcactttgatgatgatgaacga
tggacagatgatgtcacaggtaccaacctattcctggttgctgctcatgaacttggccac
tccctgggtctctttcactcagccaatgctgaagctttgatgtacccagtctacaagtcc
tccacagacctggcccgtttccatctctctcaagatgatgtagatggtattcaatccctc
tatggacctcccacagaatcccctgatgtcctcgtggtacccaccaaatctaactctctg
gaccctgagaccttaccaatgtgtagctctgctttgtccttcgatgcagtcagcaccctg
cggggagaagtcttgttctttaaagacaggcacttttggcgaaaatctctcaggacccct
gagcctggcttttatttgatctcttcattttggccgtctcttccatccaacatggatgct
gcatatgaagttactaacagagacactgttttcattcttaaaggaaatcagatctgggct
atccgaggtcatgaagagctagcaggttatcctaaaagcattcacactctgggcctccct
gaaaccgtccagaagatcgatgcagccatttctttaaaggaccaaaagaagacgtacttc
tttgtagaggacaaattctggagatttgatgagaagaaacaatccatggatccaggattt
cccaggaaaatagctgagaactttccaggcattggcacaaaggtggatgctgtctttgaa
gcatttgggtttctttacttcttcagcggatcttcacagttggagtttgatccaaatgca
gggaaagtgacccacatattgaagagcaacagctggtttaattgttaa

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (21)   

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