KEGG   Rattus norvegicus (rat): 294924
Entry
294924            CDS       T01003                                 
Symbol
Mecom
Name
(RefSeq) histone-lysine N-methyltransferase MECOM
  KO
K04462  [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00310  Lysine degradation
rno01100  Metabolic pathways
rno04010  MAPK signaling pathway
rno05200  Pathways in cancer
rno05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    294924 (Mecom)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    294924 (Mecom)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    294924 (Mecom)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    294924 (Mecom)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    294924 (Mecom)
   03036 Chromosome and associated proteins [BR:rno03036]
    294924 (Mecom)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.367  [histone H3]-lysine9 N-methyltransferase
     294924 (Mecom)
Transcription factors [BR:rno03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 PRDM
    294924 (Mecom)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     294924 (Mecom)
SSDB
Motif
Pfam: zf-C2H2 zf-H2C2_2 zf-C2H2_4 PRDM2_PR zf-C2H2_6 zf-C2H2_jaz SET zf-H2C2_5 zf-BED C2CH-3rd_BIRD-IDD Zap1_zf1 zf-C2H2_8 zf-C2HE
Other DBs
NCBI-GeneID: 294924
NCBI-ProteinID: NP_001376211
RGD: 1310997
Ensembl: ENSRNOG00000012645
Position
2:114837815..115393052
AA seq 1242 aa
MRSKGRARKLATSNECAYGNYPEIPLEEMPDAEDADGIANAPSLHIQEPCSPATSSESFT
PKEGSPYKAPIYIPDDIPIPDEFELRESTMPGAGLGIWTKRKIEIGEKFGPYMGEQRSDL
KDSSYGWEILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVA
DIAPGEELLLFMKSEEDPHEPMAPDIHEERQHRCEDCDQLFESKAELADHQKFPCSTPHS
AFSMVEEDLQQNLESESDLREIHGNQDCKECDRVFPDLQSLEKHMLSHTEEREYKCDQCP
KAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKT
FATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFST
TSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMGHANPGLVDYFGTNRHP
AGLTFPTAPGFSLSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQSNKCQSPLLTHPQILP
ATQDILKALSKHPPVGDNKPVELLPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETT
SGSDLESDLESDKEKCKENGKMFKDKVSPLQNLASINNKKEYSNHSVFSASVEEQTAVSG
AVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLR
SLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTSGSSKLPATPATSQDQPLDLS
MGSRSRASGTKLTEPRKNHVFGEKKGSNMETRPSSDGSLQHARPTPFFMDPIYRVEKRKL
TDPLEALKEKYLRPSPGFLFHPQFPLPDQRTWMSAIENMAEKLESFSGLKPEASELLQSV
PSMFSFRAPPNTLPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDR
SFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSE
LESAGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNMEERMNGSHFKDEKALATSQNSDLL
DDEEVEDEVLLDEEDEDNDIPGKPRKELGVTNLDEEIPEDDYEEAGALEMSCKVSPVRYK
EEDYKSGLSALDHIRHFTDSLKMREMEENQYTDAELSFGSSHVPEELKQPLHRKSKSQAY
AMMLSLSDKDALHPTSHGSSNVWHSMARAAAESSAIQSISHV
NT seq 3729 nt   +upstreamnt  +downstreamnt
atgagatccaaaggcagggcaaggaaactggccacaagtaatgagtgtgcttatggcaac
taccctgaaatacccttggaagaaatgccagatgccgaagatgcagatgggatagccaat
gctccctcccttcacatccaagagccatgctctcctgcgacatccagtgagtcatttact
cctaaggagggctcgccctacaaagcccccatctacatccccgatgacatccccattcct
gatgaattcgagcttcgagagtcaactatgcctggagcaggacttggaatatggaccaaa
aggaagattgaaataggagaaaagtttgggccatacatgggagagcagagatcagacctg
aaagattccagctatggatgggagatcttagatgagttttgcaatgtgaagttctgcata
gatgccagtcaaccagatgtaggaagctggctcaagtacatccgattcgctggctgctac
gatcagcacaaccttgttgcatgccagataaacgatcagatattctacagagtagtcgca
gacattgcgcctggggaggaactcctgctgttcatgaagagtgaagaggacccacatgag
cccatggcgcctgacatccatgaagaacggcagcaccgctgtgaggactgtgaccagctc
tttgaatccaaggctgagctggctgatcaccagaagttcccatgcagcacacctcactcg
gccttctccatggtggaggaggacttgcagcaaaacctggagagtgagagtgatctccga
gagatccatggcaaccaggactgtaaggaatgtgaccgagttttccccgatctacaaagc
ttggagaagcacatgttgtcacacactgaggagagggaatacaagtgtgatcagtgcccc
aaggcatttaactggaagtccaatttaattcgccaccagatgtcacatgacagtggaaag
cactatgagtgtgaaaactgtgccaagcaggttttcacggaccctagcaaccttcagcga
cacattcgatctcagcatgttggtgcccgggctcatgcttgcccggagtgtggtaaaaca
tttgccacttcgtcaggcctcaaacaacacaagcacatccacagcagtgtgaagcccttt
atctgtgaggtctgccataaatcctatactcagttttcaaacctttgtcgtcataagcgc
atgcatgctgattgcagaacccaaatcaagtgcaaagactgtggacaaatgttcagcact
acgtcttccttaaataaacacaggaggttttgtgagggcaagaaccattttgcggcaggt
ggattttttggccaaggcatttcacttcctggaaccccagctatggataaaacgtccatg
gttaatatgggccacgccaacccgggcctggttgactattttggcaccaataggcatcct
gctggtcttacctttccaacagctccgggattttccttgagctttcctggtctgtttcct
tcgggcttgtaccacaggcctcctttgatacccgctagctctcctgttaaaggactatca
agtaccgaacagtcaaacaaatgtcaaagtcccctcttgacacatcctcagatactgcca
gccacccaggatattttgaaggcactatctaaacacccacctgtaggggacaataagcca
gtggaactgctgcccgagaggtcctctgaagagaggccccttgagaaaatcagtgaccag
tcagagagtagtgaccttgatgatgtcagtacgccaagtggcagtgatctggaaacaacc
tcgggctctgatctggaaagtgaccttgaaagtgataaagagaaatgtaaagaaaatggt
aaaatgttcaaagacaaagtaagccctctgcagaatctggcttcaataaataataagaaa
gaatacagcaatcattccgttttctcagcatctgtagaggagcagaccgcggtgtcagga
gctgtgaatgattctataaaggctattgcgtctattgctgaaaaatactttggttccaca
ggactggtggggctgcaagacaaaaaagtcggagcgttaccttacccttccatgtttccc
ctcccgttttttccagcattctctcaatcaatgtacccatttcctgatagagacttgagg
tcgttacctttgaaaatggagccccaatcaccaagtgaagtaaagaaactgcagaaggga
agctctgagtccccttttgacctcaccactaagagaaaggacgagaagcccttgacttca
ggctcctcaaagcttccagcaacacccgccacaagccaagaccagcccctggatctaagt
atgggcagtaggagtagagccagtgggacaaagttgactgagcctcgaaaaaaccatgtg
tttggggaaaagaaaggaagcaacatggaaacaaggccatcttcagatggctccttgcag
catgccagacccactcccttcttcatggatcccatttatagagtagagaaaagaaagctc
actgatccgcttgaagctttgaaagaaaaatacttgagaccttctccaggattcttgttt
cacccacaattcccactacctgaccagagaacatggatgtcggctatcgagaacatggcg
gaaaaactagaaagcttcagcggcctgaaaccagaggccagcgagctcctgcagtcagtg
ccctctatgttcagcttccgggctcctcccaacaccctgccagagaacctgctgcggaag
ggaaaggaacgctatacctgcaggtactgtggtaagattttcccaaggtctgcaaaccta
acacggcatttgagaacccacacaggagagcaaccttacagatgcaaatactgcgataga
tcattcagtatttcctccaacctgcagcgacacgtgcgcaacattcacaacaaggagaag
ccatttaagtgtcacctatgtgacagatgctttggtcaacaaaccaatcttgacagacac
ctgaagaaacacgagaacgggaacatgtctggtacagcaacatcctcgcctcattcggag
ctagaaagcgcaggtgccatcctggatgacaaagaagatgcttactttacagagatccgc
aatttcatcgggaatagcaaccatgggagccagtctcctcggaacatggaggagaggatg
aatggcagtcacttcaaggatgaaaaggctttggcgaccagccaaaattccgatttattg
gatgacgaagaagtagaggatgaggtgttgctggatgaggaggatgaagacaatgatatt
cctggaaaacccagaaaggagctgggggtaactaatttagatgaggaaatccctgaggat
gactatgaggaagccggtgccctggagatgagttgtaaggtgtcccccgtgaggtataaa
gaggaagactataaatctggcctttctgctctagatcacataaggcacttcacagatagc
ctcaaaatgagggaaatggaagagaatcaatacactgacgctgagctgtcctttggttct
tctcatgtgccagaggagcttaaacagccgttacacagaaagtccaaatcacaggcatat
gctatgatgttgtcactgtctgacaaggatgccctccatcccacctcccacggttcctcc
aacgtgtggcacagcatggcaagagctgcagcggaatccagtgccatccagtccataagc
catgtatga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (17)   
   RefSeq(pep) (17)   
DNA sequence (18)   
   RefSeq(nuc) (18)   
Protein domain (13)   
   Pfam (13)   
All databases (53)   

Download RDF
DBGET integrated database retrieval system