KEGG   Ursus maritimus (polar bear): 103680825
Entry
103680825         CDS       T03271                                 
Symbol
MECOM
Name
(RefSeq) histone-lysine N-methyltransferase MECOM isoform X1
  KO
K04462  [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00310  Lysine degradation
umr01100  Metabolic pathways
umr04010  MAPK signaling pathway
umr05200  Pathways in cancer
umr05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    103680825 (MECOM)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103680825 (MECOM)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103680825 (MECOM)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    103680825 (MECOM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:umr03000]
    103680825 (MECOM)
   03036 Chromosome and associated proteins [BR:umr03036]
    103680825 (MECOM)
Enzymes [BR:umr01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.367  [histone H3]-lysine9 N-methyltransferase
     103680825 (MECOM)
Transcription factors [BR:umr03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 PRDM
    103680825 (MECOM)
Chromosome and associated proteins [BR:umr03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     103680825 (MECOM)
SSDB
Motif
Pfam: zf-C2H2 zf-H2C2_2 zf-C2H2_4 zf-C2H2_6 zf-C2H2_jaz zf-H2C2_5 C2CH-3rd_BIRD-IDD Zap1_zf1 zf-BED zf-C2H2_8 C2CH-4th_BIRD-IDD zf-C2H2_11 CEP104_ZnF
Other DBs
NCBI-GeneID: 103680825
NCBI-ProteinID: XP_040477559
UniProt: A0A8M1F9S4
Position
Unknown
AA seq 1052 aa
MKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDFQQ
KLESENDLRDIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIR
HQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHK
HIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFC
EGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGF
SFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSK
HPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIES
DKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIAS
IAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSP
NEVKKLQKGSSESPFDLTTKRKDEKPLTPGPSKPPATPVTSQDQPLDLSMGSRSRASGTK
LTEPRKNHVFGEKKGSNIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKY
LRPSPGFLFHPQFQLPDQRTWMSAIENMAEKLESFSALKPEASELLQSVPSMFNFRAPPN
ALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRH
VRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDK
EDAYFTEIRNFIGNSNHSSQSPRNTEERMNGSHFKDEKALVTSQNSDLLDDEEVEEEVLL
DEEDDDNDITGKTGKEPGTSNLHEGNPEDDYEEASALEMSCKASPVRYKEEEYKTGLSAL
DHIRHFTDSLKMRKLEDNQYSEAELSSFSASHVPEELKQPLHRKSKSQAYAMMLSLSDKE
SLHSTSHSSSNVWHTMARAAAESSAIQSVSHV
NT seq 3159 nt   +upstreamnt  +downstreamnt
atgaagagtgaagactatccccatgaaactatggcgccggatatccacgaagaacggcaa
tatcgctgcgaggactgtgaccagctctttgagtccaaggctgagctagcagatcaccag
aagttcccctgcagtacccctcactcagcattttcaatggtggaagaagacttccaacaa
aaacttgaaagcgaaaacgatctccgagacatacatgcaatccaggagtgtaaggaatgt
gaccaagttttccccgatttgcaaagcctggagaaacacatgttgtcacatactgaagag
agggaatacaagtgcgatcagtgtcccaaggcatttaactggaagtccaatctaattcgc
caccagatgtcacatgacagtggaaagcactatgaatgtgaaaactgtgccaagcaggtt
ttcacggaccctagcaaccttcagcggcacatccgctctcagcatgttggtgcccgggcc
cacgcgtgcccggagtgtggcaaaacgtttgccacttcgtcgggcctcaaacaacacaag
cacatccacagcagtgtgaagccctttatctgtgaggtctgccataaatcctatactcag
ttttcaaacctttgtcgtcataagcgcatgcatgctgattgcagaacccaaatcaagtgc
aaagactgtggacaaatgttcagcactacgtcttccttaaataaacacaggaggttttgt
gagggcaagaaccattttgcggcaggtggattttttggccaaggcatttcacttcctgga
acccccgctatggataaaacgtccatggttaatatgagtcatgccaacccgggccttgct
gactattttggtgccaataggcatcccgctggtcttacctttccaacagctcctggattt
tcttttagcttccctggtctgtttccttccggcttgtaccacaggcctcctttgatacct
gctagctctcctgttaaaggactatcaagtactgaacagacaaacaaaagtcaaagtccc
ctcatgacacatcctcagatactgccagctacacaggatattttgaaagcactatctaaa
cacccacctgtaggagacaataagccagtggagctccagcccgagaggtcctctgaagag
aggccccttgagaaaatcagtgaccagtcagagagtagtgaccttgatgatgtcagtacg
ccaagtggcagtgacctggaaacaacctcgggctctgatctggaaagtgacattgaaagt
gataaagagaaatttaaagaaaatggtaaaatgttcaaagacaaagtaagccctcttcag
aatctggcttcaatacataataagaaagaatacagcaatcattccattttctcaccatct
ttagaggagcaaactgcggtgtcaggagctgtgaatgattctataaaggctattgcttct
attgctgaaaaatactttggttcaacaggactggtggggctgcaagacaaaaaagttgga
gctttaccttacccttccatgtttcccctcccattttttccagcattctctcaatcaatg
tacccatttcctgatagagacttgagatcgttacctttgaaaatggaaccccaatcacca
aacgaagtaaagaaactgcagaagggaagctctgagtctccctttgatctcaccactaag
cgaaaggacgagaagcccttgactccaggaccctccaagcctccagcaacacctgtcaca
agccaagaccagcccctggatctaagtatgggcagtaggagtagagccagtggaacgaag
ctgactgagccccgtaaaaaccacgtgtttggggaaaagaaaggaagcaatattgaacca
agacccgcatcggacggttccttgcagcacgctagacccactcctttctttatggaccca
atttacagagtagagaaaagaaaactaactgacccacttgaagctttaaaagagaaatac
ttgagaccttctccaggattcttatttcacccacaattccaactgcctgatcagagaact
tggatgtcagctattgaaaacatggcagagaagttagagagcttcagtgccctgaaaccg
gaggccagcgaacttctgcagtcagttccctccatgttcaacttcagagcacctcccaat
gccttgccggagaacctcctgcggaaagggaaagagcgctacacctgcagatactgtggc
aagatttttccaaggtctgcgaacttaacacggcacttgagaacccacacaggagagcaa
ccttacagatgcaaatactgtgacagatcctttagcatctcctccaacttgcagaggcat
gtccggaacatccacaataaggagaagccctttaagtgtcacttatgtgataggtgtttt
ggtcaacaaaccaacttagacagacacctaaagaaacatgagaatgggaacatgtctggt
acggcaacgtcgtcgcctcattccgaactggagagcacaggcgcgattctcgatgacaaa
gaagatgcttacttcacagaaatccgcaatttcattgggaacagcaaccacagcagccaa
tctcccaggaacacagaggagaggatgaacggcagtcattttaaggatgagaaagctttg
gtgaccagccaaaattcagatttactggatgatgaagaagtagaagaggaggtgttgtta
gatgaggaggacgatgacaacgacattactggaaaaacgggaaaagagccagggacaagc
aatttacatgaaggaaaccctgaggatgactatgaagaagccagcgccctggagatgagt
tgcaaagcgtccccagtgaggtataaagaggaagaatataaaactggactttctgctcta
gatcatataaggcacttcacagatagcctcaaaatgaggaaactggaagataatcaatat
tctgaagctgagctgtcttcttttagtgcttcccatgtgccggaggaacttaaacagccg
ttacacagaaagtccaaatcacaggcatatgctatgatgttgtcactgtccgacaaggag
tccctccattctacatcccacagttcttccaacgtgtggcacactatggcaagggctgcg
gcggaatccagtgccatccagtccgtaagccacgtatga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (13)   
   Pfam (13)   
All databases (31)   

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