Target-based Classification of Drugs

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 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
   Oxidoreductases (EC1)
   Transferases (EC2)
   Hydrolases (EC3)
     Carboxylic-ester hydrolases [EC:3.1.1.-]
     Phosphatases [EC:3.1.3.-]
     Phosphodiesterases [EC:3.1.4.-]
       SMPD1* [HSA_VAR:6609v1] [HSA:6609] [KO:K12350]
       PDE [HSA:10846 27115 50940 5136 5137 5138 5139 5140 5141 5142 5143 5144 5150 5151 5153 8622] [KO:K18438 K18436 K13298 K13755 K18283 K19021 K13296 K13293 K18437]
         D07425  Papaverine (BAN)
         D02218  Papaverine hydrochloride (JP18/USP) <JP>
         D07439  Papaverine sulfate
         D07089  Moxaverine (INN)
         D08238  Moxaverine hydrochloride
         D07546  Bucladesine (INN)
         D01238  Bucladesine sodium (JAN) <JP>
         D01220  Trapidil (JP18/INN) <JP>
         D07961  Flavoxate (INN)
         D00718  Flavoxate hydrochloride (JP18/USP) <JP/US>
         D00691  Dyphylline (USP) <JP>
         D02017  Oxtriphylline (USP)
         D01771  Proxyphylline (JAN/INN) <JP>
         D00371  Theophylline (JP18) <JP/US>
         D01712  Theophylline sodium acetate (JAN)
         D06103  Theophylline (USP)
         D06104  Theophylline sodium glycinate (USP)
         D00227  Aminophylline (USP/INN)
         D05429  Aminophylline hydrate (JP18) <JP>
         D11630  Aminophylline dihydrate <US>
         D03075  Bemoradan (USAN/INN)
         D04006  Enprofylline (USAN/INN)
         D05278  Oxagrelate (USAN/INN)
         D05612  Prinoxodan (USAN/INN)
         D06132  Tibenelast sodium (USAN)
         D09822  Theosalicin (JAN)
       PDE [HSA:5153 5138 5139 5140 5141 5142 5143 5144 8654] [KO:K13755 K18283 K19021 K13296 K13293 K13762]
       PDE1 [HSA:5136 5153 5137] [KO:K13755]
       PDE2A [HSA:5138] [KO:K18283]
       PDE3 [HSA:5139 5140] [KO:K19021 K13296]
       PDE4 [HSA:5141 5142 5143 5144] [KO:K13293]
       PDE4A [HSA:5141] [KO:K13293]
       PDE4D [HSA:5144] [KO:K13293]
       PDE5 [HSA:8654] [KO:K13762]
       PDE9 [HSA:5152] [KO:K13761]
       PDE10A [HSA:10846] [KO:K18438]
       ENPP2 (ATX) [HSA:5168] [KO:K01122]
     Sulfatases [EC:3.1.6.-]
     Glycosidases [EC:3.2.1.-]
     ADP-ribosyl cyclase [EC:3.2.2.6]
     Aminopeptidases [EC:3.4.11.-]
     Dipeptidases [EC:3.4.13.-]
     Peptidyl-peptidases [EC:3.4.14.-]
     Peptidyl-dipeptidases [EC:3.4.15.-]
     Metallocarboxypeptidases [EC:3.4.17.-]
     Serine peptidases [EC:3.4.21.-]
     Cysteine peptidases [EC:3.4.22.-]
     Aspartic peptidases [EC:3.4.23.-]
     Metallo peptidases [EC:3.4.24.- 3.4.17.-]
     Threonine peptidases [EC:3.4.25.-]
     Glutaminase [EC:3.5.1.2]
     Histone deacetylase [EC:3.5.1.98]
     Arginase [EC:3.5.3.1]
     Adenosine deaminase [EC:3.5.4.4]
     Cytidine deaminase [EC:3.5.4.5]
     ATPase [EC:3.6.3.-]
   Lyases (EC4)
   Isomerases (EC5)
     Peptidylprolyl isomerase [EC:5.2.1.8]
     Prostaglandin-E synthase [EC:5.3.99.3]
     Thromboxane-A synthase [EC:5.3.99.5]
       TBXAS1 (CYP5A1) [HSA:6916] [KO:K01832]
         D07140  Picotamide (BAN)
         D01220  Trapidil (JP18/INN) <JP>
         D01683  Ozagrel hydrochloride hydrate (JAN) <JP>
         D01684  Ozagrel sodium (JP18) <JP>
         D03661  Dazmegrel (USAN/INN)
         D03663  Dazoxiben hydrochloride (USAN)
         D04276  Furegrelate sodium (USAN)
         D05502  Pirmagrel (USAN/INN)
         D05727  Ridogrel (USAN/INN)
         D06077  Terbogrel (USAN/INN)
         D08327  Ozagrel (INN)
     DNA topoisomerase [EC:5.99.1.-]
   Ligases (EC6)
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: April 24, 2024

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