Antimicrobial Resistance: beta-Lactamase Genes Antimicrobial Resistance: beta-Lactamase Genes| FASTA sequence file: | beta-Lactamases |
| Phylogenetic trees: | beta-Lactamases Class A Class D Class C Class B |
See also: NCBI antimicrobial resistance reference gene database
| Class | Subclass | KO | Remark | |
| Serine | A | K18698(TEM) | ||
| K18699(SHV) | ||||
| K18796(LEN) | (Klebsiella) | |||
| K24159(LAP) | (Enterobacter) | |||
| K18795(CARB-1) | PSE family | |||
| K19217(CARB-17) | (Vibrio) | |||
| K19218(CARB-5) | RTG family (Acinetobacter, Psychrobacter) | |||
| K18767(CTX-M) | ||||
| K24153(OXY) | (Klebsiella) | |||
| K18768(KPC) | ||||
| K19316(IMI) | (Enterobacter) | |||
| K22346(SME) | (Serratia) | |||
| K18970(GES) | ||||
| K19317(BEL) | (Pseudomonas) | |||
| K19097(VEB) | ||||
| K18797(PER) | ||||
| unclassified | K17836(penP) | |||
| D | 2d | K18794(OXA-51) | OXA-51 family (Acinetobacter) | |
| K19318(OXA-213) | OXA-213 family (Acinetobacter) | |||
| K18971(OXA-24) | OXA-24 family (Acinetobacter) | |||
| K18973(OXA-50) | (Pseudomonas) | |||
| K19319(OXA-134) | OXA-134 family (Acinetobacter) | |||
| K19320(OXA-211) | OXA-211 family (Acinetobacter) | |||
| K21266(OXA-286) | OXA-286 family (Acinetobacter) | |||
| K19321(OXA-214) | OXA-214 family (Acinetobacter) | |||
| K19322(OXA-229) | OXA-229 family (Acinetobacter) | |||
| K18972(OXA-58) | OXA-58 family (Acinetobacter) | |||
| K18793(OXA-23) | OXA-23 family (Acinetobacter) | |||
| K21277(OXA-60) | (Ralstonia) | |||
| K18976(OXA-48) | OXA-48 family | |||
| K18792(OXA-10) | OXA-10 family | |||
| K18791(OXA-2) | OXA-2 family | |||
| K19211(OXA-62) | OXA-62 family (Pandoraea) | |||
| K22334(OXA-464) | (Arcobacter) | |||
| K22351(OXA-209) | ||||
| K19212(OXA-63) | OXA-63 family (Brachyspira) | |||
| K22331(OXA-184) | OXA-184 family (Campylobacter) | |||
| K19210(OXA-61) | (Campylobacter) | |||
| K22333(OXA-493) | OXA-493 family (Campylobacter) | |||
| K22232(OXA-548) | (Campylobacter) | |||
| K22335(OXA-114) | OXA-364 family (Achromobacter) | |||
| K19209(OXA-42) | (Burkholderia) | |||
| K21276(OXA-22) | (Ralstonia) | |||
| K19098(OXA-9) | ||||
| K19213(OXA-12) | (Aeromonas) | |||
| K18790(OXA-1) | OXA-1 family | |||
| K22352(OXA-29) | (Legionella) | |||
| unclassified | K17838(OXA) | |||
| C | K19096(CMY) | CMY, CFE, LAT | ||
| K19215(ACT_MIR) | ACT, MIR | |||
| K19100(DHA) | ||||
| K19095(CMY_MOX) | CMY, MOX | |||
| K19101(FOX) | ||||
| K20320(PDC) | (Pseudomonas) | |||
| K19214(ACC) | ||||
| K20319(ADC) | (Acinetobacter) | |||
| unclassified | K01467(ampC) | |||
| Metallo | B | B1 | K18782(IMP) | |
| K19099(GIM) | ||||
| K18781(VIM) | ||||
| K18780(NDM) | ||||
| K19216(IND) | (Chryseobacterium) | |||
| K24162(BlaB) | (Elizabethkingia) | |||
| B3 | K24161(GOB) | (Elizabethkingia) | ||
| unclassified | K17837(bla2) | |||
| Class | Drug group | Drug examples | Enzyme examples | Natural product (biosynthesis) | |
| beta-Lactamase sensitive penicillin (DG01778) |
Benzylpenicillin (DG00534) | Penicillinase | Penicillin (map00311) | ||
| beta-Lactamase resistant penicillin (DG01779) |
Meticillin (DG02500) Oxacillin (DG00542) |
Oxacillinase | |||
| Extended spectrum penicillin (DG01780) |
Ampicillin (DG00517) Carbenicillin (DG00519) |
Carbenicillinase | |||
| beta-Lactamase inhibitor (DG01479) |
Sulbactam (DG00545) Tazobactam (DG00546) |
||||
| Clavulanic acid (DG01261) | Clavaminate (map00331) | ||||
| Carbapenem (DG01458) | Imipenem (DG01212) | Carbapenemase Imipenemase |
Carbapenem-3-carboxylate (map00332) |
||
| First-generation cephalosporin (DG01774) |
Cefaloridine (D01075) | Cephalosporinase | Cephamycin C (map00311) | ||
| Second-generation cephalosporin (DG01775) |
Cefoxitin (DG00557) | Cephamycinase | |||
| Flomoxef (DG00569) | |||||
| Loracarbef (DG00564) | |||||
| Third-generation cephalosporin (DG01776) |
Cefotaxime (DG00570) Ceftazidime (DG00571) |
Extended-spectrum beta-lactamase (ESBL) |
|||
| Latamoxef (DG00575) | |||||
| Fourth-generation cephalosporin (DG01777) |
Cefepime (DG01777) | ||||
| Monobactam (DG01454) | Aztreonam (DG00589) | Nocardicin A (map00261) | |||