KEGG Antimicrobial Resistance: Tetracycline Resistance Genes

Name	KEGG	PubMed	GenBank	Species	Length	KO
tet(A)	ag:AAN06707	14613948	AF534183	Shigella sonnei	424	K08151
tet(B)	ag:AAF68936	10783303	AF223162	Salmonella enterica	401	K08151
tet(C)	ag:AAK97748	12151232	AY043298	Aeromonas salmonicida	396	K08151
tet(D)	ag:CAA46706	8384294	X65876	Salmonella enterica	394	K08151
tet(E)	ag:AAA71915	3241623 8331085	L06940	Escherichia coli	405	K08151
tet(G)	ag:AAC98496	10103189	AF071555	Salmonella enterica	375	K08151
tet(H)	ag:AAC43250	8109938	U00792	Pasteurella multocida	400	K08151
tet(J)	ag:AAD12753	9838156	AF038993	Proteus mirabilis	398	K08151
tet(K)	ag:CAI59787	15980097	AJ888003	Staphylococcus lentus	459	K08168
tet(L)	ag:CAA30827	2844262	X08034	Bacillus subtilis	458	K08168
tetA(P)	ag:AAA20116	8170402	L20800	Clostridium perfringens	420	K18214
tet(V)	ag:AAB84282	9687386	AF030344	Mycobacterium smegmatis	419	K18215
tet(Y)	ag:AAC72341		AF070999	Escherichia coli	391	K08151
tet(Z)	ag:AAD25063	11078655	AF121000	Corynebacterium glutamicum	384	K08151
tet(30)	ag:AAD09860	9882678	AF090987	Agrobacterium fabrum	394	K08151
tet(31)	ag:ACU65232	21145184	GQ283908	Gallibacterium anatis	410	K08151
tet(33)	ag:CAD12227	12383729	AJ420072	Corynebacterium glutamicum	407	K08151
tet(35)	ag:AAK37619	11897587	AF353562	Vibrio harveyi	369	K18218
tet(38)	ag:AAV80464	15774883	AY825285	Staphylococcus aureus	450	K08168
tet(39)	ag:AAW66497	15761075	AY743590	Acinetobacter sp. LUH5605	395	K08151
tet(40)	ag:CAM12479	18779355	AM419751	uncultured bacterium	406	K18214
tet(41)	ag:AAP93922	17308196	AY264780	Serratia marcescens	393	K08151
tet(42)	ag:ACD35503	18809935	EU523697	Micrococcus sp. SMCC G887	428	K08151
tet(43)	ag:ACS83748	20453147	GQ244501		519
tet(45)	ag:AEM62953	23595824	JF837331	Bhargavaea cecembensis	458	K08168
tetA(46)	ag:AET10444	22941900	HQ652506	Streptococcus australis	574	K18216
tetB(46)	ag:AET10445	22941900	HQ652506	Streptococcus australis	578	K18217
otr(B), tet347	ag:AAD04032	9867793	AF079900	Streptomyces rimosus	563	K19542
otr(C)	ag:AAR96052	15837373	AY509111	Streptomyces rimosus	280	K18233
tcr	ag:BAA07390	8534971	D38215	Streptomyces aureofaciens	512	K19542
tet(M)	ag:AAB05245	9372426	U58985	Gardnerella vaginalis	639	K18220
tet(O)	ag:AAA23033	2836268	M18896	Campylobacter jejuni	639	K18220
tetB(P)	ag:AAA20117	8170402	L20800	Clostridium perfringens	652	K18220
tet(Q)	ag:AAA62400	7944364	L33696	Prevotella ruminicola	641	K18220
tet(S)	ag:AAA25293	8370538	L09756	Listeria monocytogenes	641	K18220
tet(T)	ag:AAF01499	8980765	L42544	Streptococcus pyogenes	651	K18220
tet(W)	ag:CAA10975	9292992	AJ222769	Butyrivibrio fibrisolvens	639	K18220
tet(32)	ag:ABG36114	17178791	DQ647324	Streptococcus salivarius	639	K18220
tet(36)	ag:CAD55718	12839793	AJ514254	Bacteroides coprosuis	640	K18220
tet(44)	ag:CBH51823	20479200	FN594949	Campylobacter fetus	640	K18220
otr(A)	ag:CAA37477	1809836	X53401	Streptomyces rimosus	663	K18220
tet	ag:AAA26830	1510403	M74049	Streptomyces lividans	639	K18220
tet(X)	ag:AAA27471	1846135	M37699	Bacteroides fragilis	388	K18221
tet(34)	ag:BAB59035	11959596	AB061440	Vibrio sp. No.6	154
tet(37)	ag:AAN28721	12654685	AF540889		108
tet(U)	ag:AAB08924	8700968	U01917	Enterococcus faecium	105

Mechanism	KO	Remark
Efflux genes	K08151	tet(A/B/C/D/E/G/H/J/Y/Z/30/31/33/39/41/42)
	K08168	tet(K/L/38/45)
	K18214	tetA(P)/tet(40)
	K18215	tet(V)
	K18218	tet(35)
		tet(43)
	K18216	tetA(46)
	K18217	tetB(46)
	K19542	otr(B)/tcr
	K18233	otr(C)
Target protecting genes	K18220	tet(M/O/Q/S/T/W/32/36/44)/tetB(P)/otr(A)/tet
Inactivating genes	K18221	tet(X)
Mechanism unknown		tet(34)
		tet(37)
		tet(U)

FASTA sequence file:	Tetracycline resistance genes
Phylogenetic tree:	Tetracycline resistance genes

Antimicrobial Resistance: Tetracycline Resistance Genes

Tetracycline resistance genes

Tetracycline resistance KO