Organism name | Ascarina lucida |
---|---|
Genus | Ascarina |
Family | Chloranthaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Ascarina lucida |
---|---|
Linked NCBI taxonomy ID | 130721 |
Linked level | species |
Family in NCBI taxonomy | Chloranthaceae |
---|---|
ID | 16737 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | Magnoliophyta |
---|---|
ID | 3398 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00005374 |
Quercetin
|
CHEMBL82242
CHEMBL479232 CHEMBL1437696 |
C012526
|
14 / 2 / 2 | 2 / 1 | No. 2 | No. 15 | |
C00005373 |
Hirsutrin
/ Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside |
CHEMBL33027
CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336 |
38 / 43 / 34 | No. 2 | No. 15 | |||
C00005138 |
Astragalin
/ Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside |
CHEMBL233930
CHEMBL453290 CHEMBL1572115 |
C001579
|
10 / 6 / 7 | 0 / 1 | No. 2 | No. 15 | |
C00001078 |
Lutexin
/ Orientin / Luteolin 8-C-beta-D-glucopyranoside / 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone |
CHEMBL520866
CHEMBL1468796 |
C065886
|
20 / 15 / 14 | No. 22 | No. 15 | ||
C00001059 |
Isovitexin
/ Saponaretin / Homovitexin / 6-C-beta-D-Glucopyranosylapigenin / 6-beta-D-Glucopyranosyl-4',5,7-trihydroxyflavone / 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL465360
CHEMBL1601394 |
C049772
|
28 / 20 / 19 | No. 22 | No. 15 | ||
C00001110 |
Vitexin
/ Apigenin 8-C-glucoside / 8-D-Glucosyl-4',5,7-trihydroxyflavone / 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL487417
CHEMBL1332209 CHEMBL1357921 |
16 / 4 / 8 | No. 22 | No. 15 | |||
C00001055 |
Isoorientin
/ Homoorientin / Lespecapitioside / Luteolin 6-C-beta-D-glucopyranoside / 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one |
CHEMBL239559
CHEMBL1302308 |
C057912
|
23 / 14 / 17 | 0 / 1 | No. 22 | No. 15 | |
C00004565 |
Kaempferol
/ Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL150
|
C006552
|
76 / 69 / 87 | 86 / 8 | No. 71 | No. 15 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001055 C00001059 C00001078 C00001110 C00004565 C00005138 C00005373 C00005374 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00001055 C00001059 C00001078 C00001110 C00004565 C00005138 C00005373 C00005374 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00001055 C00001059 C00001078 C00001110 C00004565 C00005138 C00005373 C00005374 | 1 / 1 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001055 C00001059 C00001078 C00004565 C00005373 C00005374 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00001055 C00001059 C00001078 C00001110 C00005373 C00005374 | 0 / 0 |
P15121 | Aldose reductase | Enzyme | C00001110 C00004565 C00005138 C00005373 C00005374 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00001055 C00001059 C00004565 C00005373 C00005374 | 0 / 0 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001055 C00001059 C00001078 C00001110 C00005374 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001055 C00001059 C00001078 C00001110 C00005138 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00001055 C00001059 C00001078 C00004565 C00005374 | 0 / 0 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001055 C00001059 C00001110 C00005373 C00005374 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00001055 C00001059 C00001078 C00005373 | 0 / 0 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001055 C00001059 C00001110 C00005373 | 1 / 4 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00001059 C00001078 C00004565 C00005374 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00001055 C00001059 C00001078 C00005373 | 1 / 1 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001055 C00001059 C00001110 C00005373 | 0 / 1 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001055 C00001059 C00001078 C00005373 | 1 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001055 C00001059 C00001078 C00005373 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001055 C00001059 C00001078 C00004565 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00001055 C00001059 C00001078 C00004565 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001055 C00001059 C00001078 C00004565 | 1 / 2 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00001055 C00001078 C00004565 C00005373 | 4 / 3 |
P14679 | Tyrosinase | Oxidoreductase | C00004565 C00005138 C00005373 | 4 / 2 |
P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00004565 C00005373 C00005374 | 1 / 1 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001055 C00001059 C00005138 | 0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | C00001078 C00004565 C00005138 | 1 / 1 |
P07237 | Protein disulfide-isomerase | Enzyme | C00005138 C00005373 C00005374 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001110 C00004565 | 1 / 0 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001055 C00001059 | 2 / 1 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001110 C00004565 | 0 / 1 |
Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00001055 C00004565 | 0 / 0 |
Q9NPH5 | NADPH oxidase 4 | Enzyme | C00004565 C00005373 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001078 C00005373 | 0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00004565 C00005373 | 0 / 3 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001059 C00004565 | 0 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00004565 C00005373 | 6 / 4 |
P02545 | Prelamin-A/C | Unclassified protein | C00004565 C00005373 | 11 / 10 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001110 C00004565 | 0 / 1 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001110 C00004565 | 1 / 1 |
Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00004565 C00005373 | 2 / 0 |
P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00004565 C00005373 | 1 / 1 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001110 C00004565 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00001110 C00005373 | 0 / 0 |
P34949 | Mannose-6-phosphate isomerase | Enzyme | C00005373 | 1 / 1 |
P41143 | Delta-type opioid receptor | Opioid receptor | C00005373 | 0 / 0 |
Q00534 | Cyclin-dependent kinase 6 | CMGC serine/threonine protein kinase family | C00004565 | 1 / 0 |
P27487 | Dipeptidyl peptidase 4 | S9B | C00004565 | 0 / 1 |
Q12791 | Calcium-activated potassium channel subunit alpha-1 | KCNM, KCa1.x | C00004565 | 1 / 1 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001059 | 7 / 3 |
P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00005373 | 0 / 0 |
P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00005373 | 0 / 0 |
P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00005373 | 3 / 1 |
P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00004565 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00004565 | 0 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00004565 | 0 / 1 |
Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00004565 | 0 / 0 |
P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00004565 | 5 / 3 |
Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00004565 | 4 / 4 |
P06276 | Cholinesterase | Hydrolase | C00004565 | 0 / 0 |
P06280 | Alpha-galactosidase A | Enzyme | C00005373 | 1 / 1 |
P04745 | Alpha-amylase 1 | Enzyme | C00004565 | 0 / 0 |
Q96RI1 | Bile acid receptor | NR1H4 | C00004565 | 0 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00005373 | 0 / 0 |
P10696 | Alkaline phosphatase, placental-like | Enzyme | C00005373 | 0 / 1 |
Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00004565 | 0 / 0 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00004565 | 3 / 3 |
P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001059 | 2 / 2 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00004565 | 2 / 2 |
P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00004565 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00001078 | 3 / 1 |
P03372 | Estrogen receptor | NR3A1 | C00004565 | 1 / 1 |
P22303 | Acetylcholinesterase | Hydrolase | C00004565 | 1 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00005373 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00004565 | 0 / 0 |
P30989 | Neurotensin receptor type 1 | Neurotensin receptor | C00001059 | 0 / 0 |
P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00004565 | 0 / 0 |
P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00004565 | 0 / 0 |
O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00004565 | 0 / 0 |
P98170 | E3 ubiquitin-protein ligase XIAP | Other cytosolic protein | C00004565 | 1 / 1 |
Q9Y3R4 | Sialidase-2 | Enzyme | C00004565 | 0 / 0 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00004565 | 0 / 0 |
P41145 | Kappa-type opioid receptor | Opioid receptor | C00005373 | 0 / 0 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00004565 | 2 / 2 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00004565 | 0 / 0 |
P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005373 | 1 / 0 |
P10275 | Androgen receptor | NR3C4 | C00004565 | 3 / 4 |
Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00004565 | 0 / 0 |
Q04760 | Lactoylglutathione lyase | Enzyme | C00004565 | 0 / 0 |
P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00004565 | 0 / 0 |
P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00004565 | 0 / 0 |
P48147 | Prolyl endopeptidase | S9A | C00004565 | 0 / 0 |
P11388 | DNA topoisomerase 2-alpha | Isomerase | C00004565 | 0 / 0 |
P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00004565 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001059 | 0 / 0 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00004565 | 1 / 8 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00005373 | 4 / 1 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001059 | 1 / 0 |
Q9GZU7 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | Enzyme | C00004565 | 0 / 0 |
Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00005374 | 0 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00004565 | 7 / 37 |
P33527 | Multidrug resistance-associated protein 1 | drugs | C00004565 | 0 / 0 |
O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00004565 | 0 / 0 |
P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00004565 | 0 / 0 |
P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00004565 | 0 / 0 |
Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00004565 | 0 / 0 |
P49840 | Glycogen synthase kinase-3 alpha | Gsk | C00004565 | 0 / 0 |
P49841 | Glycogen synthase kinase-3 beta | Gsk | C00004565 | 0 / 0 |
P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00004565 | 0 / 0 |
P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00005138 | 0 / 3 |
P08183 | Multidrug resistance protein 1 | drug | C00004565 | 1 / 0 |
Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00004565 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00004565
C00005374
|
1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00004565
C00005374
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00004565
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00004565
|
239 | ALOX12, 12-LOX, 12S-LOX, LOG12 | arachidonate 12-lipoxygenase (EC:1.13.11.31) |
C00004565
|
405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00004565
|
472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00004565
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00004565
|
27113 | BBC3, JFY-1, JFY1, PUMA | BCL2 binding component 3 |
C00004565
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00004565
|
598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00004565
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00004565
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00004565
|
6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00004565
|
891 | CCNB1, CCNB | cyclin B1 |
C00004565
|
983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00004565
|
1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00004565
|
1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00004565
|
1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00004565
|
1147 | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) |
C00004565
|
1401 | CRP, PTX1 | C-reactive protein, pentraxin-related |
C00004565
|
1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00004565
|
37618 |
C00004565
|
||
54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00004565
|
5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00004565
|
1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00004565
|
4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00004565
|
1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00004565
|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00004565
|
1734 | DIO2, 5DII, D2, DIOII, SelY, TXDI2 | deiodinase, iodothyronine, type II (EC:1.97.1.10) |
C00004565
|
2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00004565
|
2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00004565
|
2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00004565
|
2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00004565
|
4616 | GADD45B, GADD45BETA, MYD118 | growth arrest and DNA-damage-inducible, beta |
C00004565
|
2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00004565
|
9687 | GREB1 | growth regulation by estrogen in breast cancer 1 |
C00004565
|
2938 | GSTA1, GST2, GSTA1-1, GTH1 | glutathione S-transferase alpha 1 (EC:2.5.1.18) |
C00004565
|
2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00004565
|
3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00004565
|
3043 | HBB, CD113t-C, beta-globin | hemoglobin, beta |
C00004565
|
3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | hepatocyte growth factor (hepapoietin A; scatter factor) |
C00004565
|
3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00004565
|
3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00004565
|
3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00004565
|
3567 | IL5, EDF, IL-5, TRF | interleukin 5 (colony-stimulating factor, eosinophil) |
C00004565
|
3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00004565
|
3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00004565
|
4297 | KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS | lysine (K)-specific methyltransferase 2A (EC:2.1.1.43) |
C00004565
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00004565
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00004565
|
4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) |
C00004565
|
110357 |
C00004565
|
||
4502 | MT2A, MT2 | metallothionein 2A |
C00004565
|
4586 | MUC5AC, MUC5, TBM, leB | mucin 5AC, oligomeric mucus/gel-forming |
C00004565
|
8202 | NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP | nuclear receptor coactivator 3 (EC:2.3.1.48) |
C00004565
|
4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00004565
|
4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00004565
|
4843 | NOS2, HEP-NOS, INOS, NOS, NOS2A | nitric oxide synthase 2, inducible (EC:1.14.13.39) |
C00004565
|
8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00004565
|
9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00004565
|
5241 | PGR, NR3C3, PR | progesterone receptor |
C00004565
|
10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00004565
|
8000 | PSCA, PRO232 | prostate stem cell antigen |
C00004565
|
196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00004565
|
6119 | RPA3, REPA3 | replication protein A3, 14kDa |
C00004565
|
2810 | SFN, YWHAS | stratifin |
C00004565
|
6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00004565
|
6773 | STAT2, ISGF-3, P113, STAT113 | signal transducer and activator of transcription 2, 113kDa |
C00004565
|
7019 | TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 | transcription factor A, mitochondrial |
C00004565
|
7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00004565
|
7039 | TGFA, TFGA | transforming growth factor, alpha |
C00004565
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00004565
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00004565
|
9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00004565
|
8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00004565
|
7161 | TP73, P73 | tumor protein p73 |
C00004565
|
7352 | UCP3, SLC25A9 | uncoupling protein 3 (mitochondrial, proton carrier) |
C00004565
|
54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00004565
|
54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00004565
|
54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00004565
|
54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00004565
|
54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00004565
|
54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00004565
|
7402 | UTRN, DMDL, DRP, DRP1 | utrophin |
C00004565
|
8839 | WISP2, CCN5, CT58, CTGF-L | WNT1 inducible signaling pathway protein 2 |
C00004565
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
#203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
#606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#614490 | Blood group, junior system; jr |
Q9UNQ0
|
%606641 | Body mass index; bmi |
P37231
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#609338 | Carotid intimal medial thickness 1 |
P37231
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
Q14191
|
#602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#133239 | Esophageal cancer |
P04637
|
#615363 | Estrogen resistance; estrr |
P03372
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#609446 | Generalized epilepsy and paroxysmal dyskinesia; gepd |
Q12791
|
#137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
#231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
#137760 | Glaucoma, primary open angle; poag |
Q16678
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#146300 | Hypophosphatasia, adult |
P05186
|
#241510 | Hypophosphatasia, childhood |
P05186
|
#241500 | Hypophosphatasia, infantile |
P05186
|
#612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
#601626 | Leukemia, acute myeloid; aml |
P36888
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P00533
P04637 |
#300635 | Lymphoproliferative syndrome, x-linked, 2; xlp2 |
P98170
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#257200 | Niemann-pick disease, type a |
P17405
|
#607616 | Niemann-pick disease, type b |
P17405
|
#601665 | Obesity |
P37231
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
#604229 | Peters anomaly |
Q16678
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
%612223 | Stature quantitative trait locus 11; stqtl11 |
Q00534
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278300 | Xanthinuria, type i |
P47989
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
P04637 (related) |
H00022 | Bladder cancer |
P00533
(related)
P04637 (related) |
H00028 | Choriocarcinoma |
P00533
(related)
P04637 (related) |
H00030 | Cervical cancer |
P00533
(related)
|
H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
H00082 | Graves' disease |
P01215
(marker)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
H00027 | Ovarian cancer |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
P27487 (marker) P37231 (related) |
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
P35354 (related) |
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00213 | Hypophosphatasia |
P05186
(related)
|
H00125 | Fabry disease |
P06280
(related)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00024 | Prostate cancer |
P10275
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00023 | Testicular cancer |
P10696
(marker)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
H00409 | Type II diabetes mellitus |
P37231
(related)
|
H00192 | Xanthinuria |
P47989
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00107 | Other well-defined immunodeficiency syndromes |
P98170
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H01258 | Generalized epilepsy and paroxysmal dyskinesia (GEPD) |
Q12791
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
H00296 | Defects in RecQ helicases |
Q14191
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00612 | Primary open angle glaucoma |
Q16678
(related)
|
H01075 | Peters anomaly |
Q16678
(related)
|
H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D003876 | Dermatitis, Atopic |
C00005138
|
D050197 | Atherosclerosis |
C00004565
|
D001943 | Breast Neoplasms |
C00004565
|
D009202 | Cardiomyopathies |
C00004565
|
D002318 | Cardiovascular Diseases |
C00004565
|
D006943 | Hyperglycemia |
C00004565
|
D007938 | Leukemia |
C00004565
|
D010024 | Osteoporosis |
C00004565
|
D011297 | Prenatal Exposure Delayed Effects |
C00004565
|
D010146 | Pain |
C00005374
|
D008104 | Liver Cirrhosis, Alcoholic |
C00001055
|