| class name | count |
|---|---|
| rosids | 68 |
| class name | count |
|---|---|
| Moraceae | 68 |
| br08003 Category | # of metabolite |
|---|---|
| Diels-Alder adduct of chalcone | 5 |
| KCF-S ID | # of metabolite |
|---|---|
| No. 81 | 54 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
figure |
|---|---|---|---|---|---|---|---|
|
C00001000
|
Albanin F
/ Kuwanone G |
CHEMBL444942
|
C095194
|
0 / 2 | No. 81 |
|
|
|
C00001001
|
Kuwanon K
|
No. 81 |
|
||||
|
C00001063
|
Artonin I
|
No. 81 |
|
||||
|
C00001064
|
Multicaulisin
|
No. 81 |
|
||||
|
C00002405
|
Chalcomoracin
|
CHEMBL508825
CHEMBL1808155 |
No. 81 |
|
|||
|
C00008077
|
Mulberrofuran U
|
C083337
|
No. 81 |
|
|||
|
C00008079
|
Guangsangon J
|
No. 81 |
|
||||
|
C00008080
|
Mulberrofuran E
|
No. 81 |
|
||||
|
C00008081
|
Mulberrofuran C
|
CHEMBL378806
CHEMBL505416 |
2 / 0 / 0 | No. 81 |
|
||
|
C00008082
|
Mulberrofuran J
|
CHEMBL378806
CHEMBL505416 |
2 / 0 / 0 | No. 81 |
|
||
|
C00008084
|
Albafuran C
|
No. 81 |
|
||||
|
C00008085
|
Guangsangon G
|
No. 81 |
|
||||
|
C00008086
|
Guangsangon I
|
No. 81 |
|
||||
|
C00008087
|
Kuwanone H
|
CHEMBL506234
|
C095195
|
No. 81 |
|
||
|
C00008088
|
Kuwanon N
|
No. 81 |
|
||||
|
C00008089
|
Brosimone B
|
No. 81 |
|
||||
|
C00008090
|
Mulberrofuran T
|
No. 81 |
|
||||
|
C00008091
|
Moracenin C
|
No. 81 |
|
||||
|
C00008092
|
Kuwanon W
|
No. 81 |
|
||||
|
C00008093
|
Moracenin D
|
No. 81 |
|
||||
|
C00008094
|
Guangsangon M
/ (-)-Guangsangon M |
No. 81 |
|
||||
|
C00008095
|
Guangsangon N
/ (-)-Guangsangon N |
No. 81 |
|
||||
|
C00008096
|
Kuwanon L
|
CHEMBL377937
|
2 / 0 / 0 | No. 81 |
|
||
|
C00008097
|
Guangsangon K
/ (-)-Guangsangon K |
No. 81 |
|
||||
|
C00008098
|
Sanggenon T
|
No. 81 |
|
||||
|
C00008100
|
Kuwanon O
|
No. 81 |
|
||||
|
C00008101
|
Sanggenon G
|
No. 81 |
|
||||
|
C00008102
|
Sanggenol M
|
No. 81 |
|
||||
|
C00008103
|
Guangsangon F
|
No. 81 |
|
||||
|
C00008104
|
Guangsangon H
|
No. 81 |
|
||||
|
C00008105
|
Cathayanon A
/ Cathayanone A |
No. 81 |
|
||||
|
C00008106
|
Sanggenon C
|
CHEMBL204813
CHEMBL525084 |
C477157
|
2 / 0 / 0 | No. 81 |
|
|
|
C00008107
|
Sanggenon D
|
CHEMBL464610
CHEMBL1588549 |
15 / 18 / 12 | No. 81 |
|
||
|
C00008108
|
Sanggenon O
|
No. 81 |
|
||||
|
C00008109
|
Cathayanon B
/ Cathayanone B |
No. 81 |
|
||||
|
C00008383
|
Sanggenon E
|
No. 81 |
|
||||
|
C00008384
|
Sanggenon P
|
No. 81 |
|
||||
|
C00011345
|
Sanggenol J
|
No. 81 |
|
||||
|
C00014562
|
Sanggenon Q
|
No. 81 |
|
||||
|
C00014563
|
Artonin X
|
No. 81 |
|
||||
|
C00014564
|
Kuwanon Q
|
No. 81 |
|
||||
|
C00014566
|
Kuwanon I
|
No. 81 |
|
||||
|
C00014567
|
Kuwanon J
|
No. 81 |
|
||||
|
C00014568
|
Dorstenone
|
No. 81 |
|
||||
|
C00014569
|
Kuwanon V
|
No. 81 |
|
||||
|
C00031833
|
Brosimone D
|
No. 81 |
|
||||
|
C00031835
|
Artonin C
|
No. 81 |
|
||||
|
C00031836
|
Artonin D
|
No. 81 |
|
||||
|
C00035834
|
Kuwanon X
|
No. 81 |
|
||||
|
C00035835
|
Kuwanon Y
|
No. 81 |
|
||||
|
C00035836
|
Kuwanon P
|
No. 81 |
|
||||
|
C00035837
|
Sorocein M
/ (+)-Sorocein M |
No. 81 |
|
||||
|
C00035838
|
Kuwanol E
|
No. 81 |
|
||||
|
C00045074
|
Mulberrofuran O
|
No. 81 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00001000 C00002405 C00008102 C00008384 | 0 / 0 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00001000 C00002405 C00008102 C00008384 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001001 | 2 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001001 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00001001 | 4 / 2 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001001 | 1 / 1 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001001 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001001 | 2 / 2 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001001 | 0 / 3 |
| O75496 | Geminin | Unclassified protein | C00001001 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00001001 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001001 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001001 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001001 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001001 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001001 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001001 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|