Plant Species


Cumulative plant class count

class name count
rosids 68

Cumulative family count

class name count
Moraceae 68

KCF-S cluster (1)

KCF-S ID # of metabolite
No. 81 54

Metabolite list (54)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
figure
C00001000 External link 512 Albanin F
/ Kuwanone G
CHEMBL444942
C095194
0 / 2 No. 81
C00001001 External link 512 Kuwanon K
No. 81
C00001063 External link 512 Artonin I
No. 81
C00001064 External link 512 Multicaulisin
No. 81
C00002405 External link 512 Chalcomoracin
CHEMBL508825
CHEMBL1808155
No. 81
C00008077 External link 512 Mulberrofuran U
C083337
No. 81
C00008079 External link 512 Guangsangon J
No. 81
C00008080 External link 512 Mulberrofuran E
No. 81
C00008081 External link 512 Mulberrofuran C
CHEMBL378806
CHEMBL505416
2 / 0 / 0 No. 81
C00008082 External link 512 Mulberrofuran J
CHEMBL378806
CHEMBL505416
2 / 0 / 0 No. 81
C00008084 External link 512 Albafuran C
No. 81
C00008085 External link 512 Guangsangon G
No. 81
C00008086 External link 512 Guangsangon I
No. 81
C00008087 External link 512 Kuwanone H
CHEMBL506234
C095195
No. 81
C00008088 External link 512 Kuwanon N
No. 81
C00008089 External link 512 Brosimone B
No. 81
C00008090 External link 512 Mulberrofuran T
No. 81
C00008091 External link 512 Moracenin C
No. 81
C00008092 External link 512 Kuwanon W
No. 81
C00008093 External link 512 Moracenin D
No. 81
C00008094 External link 512 Guangsangon M
/ (-)-Guangsangon M
No. 81
C00008095 External link 512 Guangsangon N
/ (-)-Guangsangon N
No. 81
C00008096 External link 512 Kuwanon L
CHEMBL377937
2 / 0 / 0 No. 81
C00008097 External link 512 Guangsangon K
/ (-)-Guangsangon K
No. 81
C00008098 External link 512 Sanggenon T
No. 81
C00008100 External link 512 Kuwanon O
No. 81
C00008101 External link 512 Sanggenon G
No. 81
C00008102 External link 512 Sanggenol M
No. 81
C00008103 External link 512 Guangsangon F
No. 81
C00008104 External link 512 Guangsangon H
No. 81
C00008105 External link 512 Cathayanon A
/ Cathayanone A
No. 81
C00008106 External link 512 Sanggenon C
CHEMBL204813
CHEMBL525084
C477157
2 / 0 / 0 No. 81
C00008107 External link 512 Sanggenon D
CHEMBL464610
CHEMBL1588549
15 / 18 / 12 No. 81
C00008108 External link 512 Sanggenon O
No. 81
C00008109 External link 512 Cathayanon B
/ Cathayanone B
No. 81
C00008383 External link 512 Sanggenon E
No. 81
C00008384 External link 512 Sanggenon P
No. 81
C00011345 External link 512 Sanggenol J
No. 81
C00014562 External link 512 Sanggenon Q
No. 81
C00014563 External link 512 Artonin X
No. 81
C00014564 External link 512 Kuwanon Q
No. 81
C00014566 External link 512 Kuwanon I
No. 81
C00014567 External link 512 Kuwanon J
No. 81
C00014568 External link 512 Dorstenone
No. 81
C00014569 External link 512 Kuwanon V
No. 81
C00031833 External link 512 Brosimone D
No. 81
C00031835 External link 512 Artonin C
No. 81
C00031836 External link 512 Artonin D
No. 81
C00035834 External link 512 Kuwanon X
No. 81
C00035835 External link 512 Kuwanon Y
No. 81
C00035836 External link 512 Kuwanon P
No. 81
C00035837 External link 512 Sorocein M
/ (+)-Sorocein M
No. 81
C00035838 External link 512 Kuwanol E
No. 81
C00045074 External link 512 Mulberrofuran O
No. 81

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00001000 C00002405 C00008102 C00008384 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00001000 C00002405 C00008102 C00008384 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001001 2 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001001 0 / 0
P37840 Alpha-synuclein Unclassified protein C00001001 4 / 2
Q99700 Ataxin-2 Unclassified protein C00001001 1 / 1
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001001 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00001001 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001001 0 / 3
O75496 Geminin Unclassified protein C00001001 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001001 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001001 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00001001 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00001001 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001001 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001001 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001001 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG name UniProt
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003731 Dental Caries C00001063
D010510 Periodontal Diseases C00001063