PCIDB

KNApSAcK Metabolite C00001001

Metabolite

KNApSAcK Entry

id C00001001
Name Sanggenon D
CAS RN 81422-93-7
Standard InChI InChI=1S/C40H36O12/c1-18(2)10-11-39-38(49)35-32(52-40(39,50)27-9-6-22(43)16-31(27)51-39)17-30(46)34(37(35)48)26-13-19(3)12-25(23-7-4-20(41)14-28(23)44)33(26)36(47)24-8-5-21(42)15-29(24)45/h4-10,13-17,25-26,33,41-46,48,50H,11-12H2,1-3H3
Standard InChI (Main Layer) InChI=1S/C40H36O12/c1-18(2)10-11-39-38(49)35-32(52-40(39,50)27-9-6-22(43)16-31(27)51-39)17-30(46)34(37(35)48)26-13-19(3)12-25(23-7-4-20(41)14-28(23)44)33(26)36(47)24-8-5-21(42)15-29(24)45/h4-10,13-17,25-26,33,41-46,48,50H,11-12H2,1-3H3

Cluster

Phytochemical cluster No. 20
KCF-S cluster No. 81

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL464610 CHEMBL1588549

KEGG

By LinkDB C09835

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Moraceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Morus cathayana 226895 Moraceae rosids Viridiplantae
Morus mongolica 229049 Moraceae rosids Viridiplantae

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL1588549 CHEMBL2114784 (1)
1 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL464610 CHEMBL1008495 (1)
0 / 3
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1588549 CHEMBL1794585 (1)
0 / 0
P37840 Alpha-synuclein Unclassified protein CHEMBL1588549 CHEMBL2354282 (1)
4 / 2
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL464610 CHEMBL1008496 (1)
0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme CHEMBL1588549 CHEMBL1794495 (1)
2 / 2
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL1588549 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL1588549 CHEMBL2114843 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1588549 CHEMBL2114788 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1588549 CHEMBL2114817 (1)
7 / 3
Q9Y253 DNA polymerase eta Enzyme CHEMBL1588549 CHEMBL1794569 (1)
1 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1588549 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1588549 CHEMBL1737991 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1588549 CHEMBL1794536 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL1588549 CHEMBL1964002 (1) CHEMBL2354311 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG disease name UniProt
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)