Species

KNApSAcK Entry

Organism name Morus mongolica
Genus Morus
Family Moraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Morus mongolica
Linked NCBI taxonomy ID 229049
Linked level species

Family

Family in NCBI taxonomy Moraceae
ID 3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (29)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004028 External link 512 Mulberrin
/ Kuwanon C
/ Norartocarpin
/ 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CHEMBL518543
3 / 0 / 3 No. 14 No. 15
C00001070 External link 512 Morusin
/ Mulberrochromene
/ 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
CHEMBL464006
C057451
16 / 17 / 10 No. 18 No. 15
C00004059 External link 512 Morusinol
/ Oxydihydromorusin
/ 2-(2,4-Dihydroxyphenyl)-5-hydroxy-3-(3-hydroxy-3-methylbutyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
CHEMBL1719948
10 / 5 / 2 No. 18 No. 15
C00004052 External link 512 Limonianin
/ Atalantoflavone
CHEMBL465808
No. 24 No. 15
C00008428 External link 512 Kuwanol C
No. 39
C00014247 External link 512 Sanggenol L
/ 5,2'.4'-Trihydroxy-6''-methyl-6''-(4-methylpent-3-enyl)-pyrano[2'',3'':7,8]flavanone
No. 39
C00008103 External link 512 Mulberrofuran O
No. 81 No. 20
C00008089 External link 512 Kuwanon J
No. 81 No. 20
C00001000 External link 512 Sanggenon C
CHEMBL204813
CHEMBL525084
C477157
2 / 0 / 0 No. 81 No. 20
C00008106 External link 512 Sanggenon E
No. 81 No. 20
C00008107 External link 512 Sanggenon O
No. 81 No. 20
C00008108 External link 512 Sanggenon P
No. 81 No. 20
C00008109 External link 512 Sanggenon Q
No. 81 No. 20
C00008383 External link 512 Sanggenon G
No. 81 No. 20
C00001063 External link 512 Albanin F
/ Kuwanone G
CHEMBL444942
C095194
0 / 2 No. 81 No. 20
C00001001 External link 512 Sanggenon D
CHEMBL464610
CHEMBL1588549
15 / 18 / 12 No. 81 No. 20
C00014564 External link 512 Sanggenol M
No. 81 No. 20
C00008384 External link 512 Kuwanon L
CHEMBL377937
2 / 0 / 0 No. 81 No. 20
C00036167 External link 512 Mulberrofuran L
CHEMBL459407
No. 319 No. 15
C00036166 External link 512 Mulberrofuran D
CHEMBL517247
1 / 0 / 0 No. 319 No. 15
C00036165 External link 512 Mulberrofuran B
CHEMBL461067
No. 319 No. 15
C00019239 External link 512 Mulberrofuran Z
/ 6,3',5'-Trihydroxy-5-methoxy-4-((2E)-3,7-dimetyl-2,6-octadienyl)-2'-prenyl-2-arylbenzofuran
CHEMBL459624
No. 319 No. 15
C00019236 External link 512 Mulberrofuran W
/ 6,3',5'-Trihydroxy-2'-((2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl)-2-arylbenzofuran
CHEMBL517415
CHEMBL562810
1 / 0 / 0 No. 319 No. 15
C00019238 External link 512 Mulberrofuran Y
/ 6,3',5'-Trihydroxy-5-methoxy-4-((2E)-3,7-dimetyl-2,6-octadienyl)-2-arylbenzofuran
CHEMBL448850
No. 319 No. 15
C00019237 External link 512 Mulberrofuran X
CHEMBL459623
No. 319 No. 15
C00008628 External link 512 Sanggenon A
CHEMBL1517104
8 / 9 / 4 No. 1072
C00008629 External link 512 Sanggenon M
No. 1072
C00008634 External link 512 Sanggenon L
No. 1072
C00008665 External link 512 Sanggenon B
No. 4698

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00001000 C00008384 C00019236 C00036166 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001001 C00001070 C00004059 C00008628 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001001 C00001070 C00004059 C00008628 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001001 C00001070 C00004059 C00008628 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001001 C00001070 C00004059 C00008628 2 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001001 C00001070 C00004059 C00008628 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001070 C00004059 C00008628 1 / 1
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001001 C00001070 C00004028 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001001 C00001070 C00004028 0 / 3
P56817 Beta-secretase 1 A1A C00001070 C00004028 C00004059 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001001 C00001070 C00004059 0 / 0
O75496 Geminin Unclassified protein C00001001 C00004059 C00008628 0 / 0
P37840 Alpha-synuclein Unclassified protein C00001001 C00001070 C00008628 4 / 2
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001001 C00001070 7 / 3
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00001000 C00008384 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001001 1 / 1
P39748 Flap endonuclease 1 Enzyme C00001070 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001001 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00001001 2 / 2
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001070 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001001 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00001070 0 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00004059 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001070 2 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (20)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P18054
P84022
#127750 Dementia, lewy body; dlb P37840
#133239 Esophageal cancer P18054
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (13)

KEGG name UniProt
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003731 Dental Caries C00001063
D010510 Periodontal Diseases C00001063