PCIDB

KNApSAcK Metabolite C00001070

Metabolite

KNApSAcK Entry

id C00001070
Name Morusin / Mulberrochromene / 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
CAS RN 62596-29-6
Standard InChI InChI=1S/C25H24O6/c1-13(2)5-7-17-22(29)21-19(28)12-20-16(9-10-25(3,4)31-20)24(21)30-23(17)15-8-6-14(26)11-18(15)27/h5-6,8-12,26-28H,7H2,1-4H3
Standard InChI (Main Layer) InChI=1S/C25H24O6/c1-13(2)5-7-17-22(29)21-19(28)12-20-16(9-10-25(3,4)31-20)24(21)30-23(17)15-8-6-14(26)11-18(15)27/h5-6,8-12,26-28H,7H2,1-4H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 18

Link

ChEMBL

By standard InChI CHEMBL464006
By standard InChI Main Layer CHEMBL464006

KEGG

By LinkDB C10106

CTD

By CAS RN C057451

Human Protein / Gene in interaction

16 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL464006 CHEMBL2114784 (1)
1 / 1
P09917 Arachidonate 5-lipoxygenase Oxidoreductase CHEMBL464006 CHEMBL1775770 (1)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL464006 CHEMBL1008495 (1) CHEMBL1775764 (1)
0 / 3
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL464006 CHEMBL1794585 (1)
0 / 0
P37840 Alpha-synuclein Unclassified protein CHEMBL464006 CHEMBL2354282 (1)
4 / 2
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL464006 CHEMBL1008496 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL464006 CHEMBL1794486 (1)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL464006 CHEMBL1794584 (1)
2 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL464006 CHEMBL2114788 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL464006 CHEMBL2114810 (1)
7 / 3
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme CHEMBL464006 CHEMBL1775771 (1)
2 / 0
P56817 Beta-secretase 1 A1A CHEMBL464006 CHEMBL1771831 (1) CHEMBL1771832 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL464006 CHEMBL1737991 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL464006 CHEMBL1738184 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL464006 CHEMBL2354311 (1)
1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL464006 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P18054
P84022
#127750 Dementia, lewy body; dlb P37840
#133239 Esophageal cancer P18054
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (10)

KEGG disease name UniProt
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)