PCIDB

Morus alba

Species

KNApSAcK Entry

Organism name Morus alba
Genus Morus
Family Moraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Morus alba
Linked NCBI taxonomy ID 3498
Linked level species

Family

Family in NCBI taxonomy Moraceae
ID 3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (54)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002378 External link 512 Cyanin
/ Cyanidin 3,5-diglucoside
No. 1 No. 15
C00006698 External link 512 Myrtillin
/ Delphinidin 3-O-beta-D-glucopyranoside
CHEMBL518846
No. 2 No. 15
C00005373 External link 512 Hirsutrin
/ Isoquercetin
/ Isoquercetrin
/ (-)-Isoquercetrin
/ Quercetin 3-glucoside
/ Quercetin 3-O-beta-D-glucoside
/ Quercetin-3-O-beta-D-glucopyranoside
/ Quercetin 3-O-beta-D-glucopyranoside
/ (-)-Quercetin-3-O-beta-D-glucopyranoside
CHEMBL33027
CHEMBL309323
CHEMBL250450
CHEMBL251254
CHEMBL457304
CHEMBL1098724
CHEMBL2337335
CHEMBL2337336
38 / 43 / 34 No. 2 No. 15
C00004624 External link 512 Morin
/ 3,5,7,2',4'-Pentahydroxyflavonol
/ 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
CHEMBL28626
C008548
59 / 40 / 67 9 / 8 No. 3 No. 15
C00013411 External link 512 Moralbanone
/ 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]-4H-1-benzopyran-4-one
No. 14 No. 15
C00004061 External link 512 Cyclomulberrin
No. 14 No. 15
C00004028 External link 512 Mulberrin
/ Kuwanon C
/ Norartocarpin
/ 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CHEMBL518543
3 / 0 / 3 No. 14 No. 15
C00004056 External link 512 Kuwanon B
No. 18 No. 15
C00004057 External link 512 Kuwanon A
CHEMBL1770312
1 / 0 / 0 No. 18 No. 15
C00001070 External link 512 Morusin
/ Mulberrochromene
/ 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
CHEMBL464006
C057451
16 / 17 / 10 No. 18 No. 15
C00004059 External link 512 Morusinol
/ Oxydihydromorusin
/ 2-(2,4-Dihydroxyphenyl)-5-hydroxy-3-(3-hydroxy-3-methylbutyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
CHEMBL1719948
10 / 5 / 2 No. 18 No. 15
C00004029 External link 512 Cyclomorusin
/ Cyclomulberrochromene
/ 6,11-Dihydroxy-3,3-dimethyl-8-(2-methyl-1-propenyl)-3H,7H,8H-bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one
CHEMBL1770313
1 / 0 / 0 No. 18 No. 15
C00008328 External link 512 Kuwanon E
CHEMBL1096939
No. 19 No. 14
C00008382 External link 512 Sanggenon N
No. 39
C00008379 External link 512 Kuwanon F
No. 39
C00008428 External link 512 Kuwanol C
No. 39
C00008381 External link 512 Sanggenon I
No. 39
C00001063 External link 512 Albanin F
/ Kuwanone G
CHEMBL444942
C095194
0 / 2 No. 81 No. 20
C00008095 External link 512 Kuwanon V
No. 81 No. 20
C00008098 External link 512 Kuwanon Y
No. 81 No. 20
C00008101 External link 512 Mulberrofuran E
No. 81 No. 20
C00008104 External link 512 Mulberrofuran T
No. 81 No. 20
C00002405 External link 512 Mulberrofuran C
CHEMBL378806
CHEMBL505416
2 / 0 / 0 No. 81 No. 20
C00008384 External link 512 Kuwanon L
CHEMBL377937
2 / 0 / 0 No. 81 No. 20
C00001064 External link 512 Kuwanone H
CHEMBL506234
C095195
No. 81 No. 20
C00008086 External link 512 Chalcomoracin
CHEMBL508825
CHEMBL1808155
No. 81 No. 20
C00008090 External link 512 Kuwanon K
No. 81 No. 20
C00008088 External link 512 Kuwanon I
No. 81 No. 20
C00008077 External link 512 Albafuran C
No. 81 No. 20
C00008089 External link 512 Kuwanon J
No. 81 No. 20
C00008081 External link 512 Artonin I
No. 81 No. 20
C00008087 External link 512 Kuwanol E
No. 81 No. 20
C00006940 External link 512 2,4,2',4'-Tetrahydroxychalcone
CHEMBL394855
1 / 2 / 2 No. 92 No. 13
C00050328 External link 512 Alboctalol
No. 108 No. 30
C00008329 External link 512 Sanggenon F
No. 127 No. 14
C00008330 External link 512 Sanggenon H
No. 127 No. 14
C00007091 External link 512 Morachalcone A
CHEMBL465880
1 / 2 / 2 No. 133 No. 13
C00007137 External link 512 Kuwanol D
No. 190 No. 13
C00002403 External link 512 Moracin A
No. 210 No. 15
C00015199 External link 512 Dihydrooxyresveratrol
/ 2,3',4,5'-Tetrahydroxystilbene
CHEMBL221291
1 / 4 / 2 No. 242 No. 26
C00002893 External link 512 Oxyresveratrol
/ 2,3,4,5'-Tetrahydroxystilbene
CHEMBL43065
20 / 32 / 49 No. 295 No. 13
C00002404 External link 512 Mulberrofuran A
No. 319 No. 15
C00002391 External link 512 Albafuran A
CHEMBL564896
1 / 0 / 0 No. 319 No. 15
C00004020 External link 512 Kuwanon S
/ Kuwanone S
/ 2-[3-(3,7-Dimethyl-2,6-octadienyl)-4-hydroxyphenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
/ 2-[3-[(2E)-3,7-Dimethyl-2,6-octadienyl]-4-hydroxyphenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
No. 319 No. 15
C00036868 External link 512 Calystegine C1
/ (+)-Calystegine C1
CHEMBL1972699
No. 643 No. 1
C00002038 External link 512 Fagomine
CHEMBL303545
CHEMBL108084
CHEMBL456583
CHEMBL505237
CHEMBL1818435
CHEMBL1818436
CHEMBL1818437
CHEMBL1818438
CHEMBL1818439
C105643
5 / 9 / 7 No. 786 No. 1
C00002900 External link 512 4'-Prenyloxyresveratrol
No. 1111 No. 13
C00002704 External link 512 Paeonol
CHEMBL1079227
C013638
4 / 2 / 3 No. 1494
C00003003 External link 512 Maclurin
CHEMBL506731
No. 1837
C00002392 External link 512 Albanol A
/ Mulberrofuran G
CHEMBL445265
CHEMBL454705
C047825
1 / 2 / 2 0 / 1 No. 2657
C00008380 External link 512 Kuwanon D
No. 3283
C00002422 External link 512 5,7-Dihydroxychromone
/ 5,7-Dihydroxy-4-chromone
C080094
No. 3998 No. 15
C00008078 External link 512 Albanol B
No. 6601
C00008099 External link 512 Kuwanon Z
No. 7833

Human Protein / Gene in interactions

112 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P56817 Beta-secretase 1 A1A C00001070 C00004028 C00004029 C00004057 C00004059 C00004624 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001070 C00002893 C00004028 C00005373 0 / 3
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001070 C00002893 C00004059 1 / 0
P39748 Flap endonuclease 1 Enzyme C00001070 C00004624 C00005373 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00002392 C00006940 C00007091 2 / 2
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001070 C00002893 C00004028 0 / 0
P14679 Tyrosinase Oxidoreductase C00002893 C00005373 C00015199 4 / 2
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001070 C00004059 C00004624 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001070 C00002893 C00004059 1 / 1
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00002391 C00002405 C00008384 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001070 C00002893 C00004059 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00002038 C00004624 C00005373 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00004624 C00005373 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00004624 C00005373 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00004624 C00005373 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00004624 C00005373 0 / 0
P06746 DNA polymerase beta Enzyme C00004624 C00005373 0 / 0
P04062 Glucosylceramidase Enzyme C00002038 C00005373 6 / 4
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002704 C00004624 0 / 1
Q99700 Ataxin-2 Unclassified protein C00001070 C00004059 1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002704 C00004624 2 / 2
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00004624 C00005373 2 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00004624 C00005373 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00004624 C00005373 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002704 C00005373 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00004624 C00005373 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00004624 C00005373 0 / 1
P37840 Alpha-synuclein Unclassified protein C00001070 C00002893 4 / 2
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00004624 C00005373 1 / 1
Q9Y253 DNA polymerase eta Enzyme C00004624 C00005373 1 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001070 C00004059 0 / 0
O75496 Geminin Unclassified protein C00004059 C00005373 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00002405 C00008384 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001070 C00004059 2 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00004624 C00005373 1 / 4
P00352 Retinal dehydrogenase 1 Enzyme C00002704 C00004624 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002893 C00004624 7 / 37
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00004624 C00005373 1 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00004624 0 / 0
P54132 Bloom syndrome protein Enzyme C00004624 1 / 2
P11388 DNA topoisomerase 2-alpha Isomerase C00004624 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005373 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00005373 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00004624 0 / 1
P17405 Sphingomyelin phosphodiesterase Enzyme C00002893 2 / 2
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00005373 1 / 1
P08183 Multidrug resistance protein 1 drug C00004624 1 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00004624 0 / 0
P04066 Tissue alpha-L-fucosidase Enzyme C00002038 1 / 2
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00002893 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00002893 4 / 2
P41143 Delta-type opioid receptor Opioid receptor C00005373 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00004624 0 / 1
P15121 Aldose reductase Enzyme C00005373 0 / 0
Q14790 Caspase-8 C14 C00004624 2 / 1
P11309 Serine/threonine-protein kinase pim-1 Pim C00004624 0 / 0
P03956 Interstitial collagenase M10A C00002893 0 / 1
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001070 7 / 3
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00005373 0 / 0
P09923 Intestinal-type alkaline phosphatase Enzyme C00005373 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00005373 3 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00004624 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00004624 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00004624 1 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00004624 0 / 0
Q96S37 Solute carrier family 22 member 12 Transporter C00004624 1 / 1
P02545 Prelamin-A/C Unclassified protein C00005373 11 / 10
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00002893 4 / 4
P06280 Alpha-galactosidase A Enzyme C00005373 1 / 1
P45452 Collagenase 3 M10A C00002893 1 / 1
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001070 2 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00004624 0 / 0
Q9HCG7 Non-lysosomal glucosylceramidase Enzyme C00002038 1 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00005373 0 / 1
P14780 Matrix metalloproteinase-9 M10A C00002893 2 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002893 0 / 0
P08253 72 kDa type IV collagenase M10A C00002893 1 / 3
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00004624 3 / 3
P39900 Macrophage metalloelastase M10A C00002893 0 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00004624 1 / 1
P29466 Caspase-1 C14 C00004624 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002893 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00005373 0 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00004624 0 / 0
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00004624 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00004624 0 / 0
P55210 Caspase-7 C14 C00004624 0 / 0
Q14697 Neutral alpha-glucosidase AB Enzyme C00002038 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00004624 0 / 0
Q15046 Lysine--tRNA ligase Enzyme C00004624 2 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00004624 2 / 2
P21728 D(1A) dopamine receptor Dopamine receptor C00004624 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00001070 0 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00004624 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001070 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00005373 1 / 0
Q04760 Lactoylglutathione lyase Enzyme C00004624 0 / 0
P08254 Stromelysin-1 M10A C00002893 1 / 0
P34949 Mannose-6-phosphate isomerase Enzyme C00005373 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00004624 2 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00004624 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00004624 0 / 0
P40225 Thrombopoietin Unclassified protein C00004624 1 / 1
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00004624 1 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00004624 1 / 1
Q16637 Survival motor neuron protein Unclassified protein C00005373 4 / 1
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00004059 0 / 0
O00255 Menin Unclassified protein C00004624 2 / 5
Q9NPH5 NADPH oxidase 4 Enzyme C00005373 0 / 0
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00004624 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005373 0 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00004624 0 / 0

9 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00004624
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00004624
3458 IFNG, IFG, IFI interferon, gamma C00004624
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00004624
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00004624
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00004624
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00004624
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00004624
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00004624

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (106)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#607271 Caspase 8 deficiency Q14790
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#114500 Colorectal cancer; crc P18054
P84022
#602579 Congenital disorder of glycosylation, type ib; cdg1b P34949
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#127750 Dementia, lewy body; dlb P37840
#119900 Digital clubbing, isolated congenital P15428
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
P18054
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#230000 Fucosidosis P04066
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#220150 Hypouricemia, renal, 1; rhuc1 Q96S37
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P04637
Q14790
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P04062
P37840
#260540 Parkinson-dementia syndrome P10636
#614674 Periodic fever, menstrual cycle-dependent P08908
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#614409 Spastic paraplegia 46, autosomal recessive; spg46 Q9HCG7
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (102)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00028 Choriocarcinoma P03956 (related)
P04637 (related)
P08253 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
P37840 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00141 Fucosidosis P04066 (related)
H00422 Glycoproteinoses P04066 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
Q92731 (marker)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00213 Hypophosphatasia P05186 (related)
H00125 Fabry disease P06280 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00118 Congenital disorders of glycosylation (CDG) type I P34949 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00057 Parkinson's disease (PD) P37840 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00108 Autoimmune lymphoproliferative syndromes (ALPS) Q14790 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00208 Hyperbilirubinemia Q92887 (related)
H00948 Renal hypouricemia (RHUC) Q96S37 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

10 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009374 Neoplasms, Experimental C00004624
C00002392
D008114 Liver Neoplasms, Experimental C00004624
D007511 Ischemia C00004624
D007674 Kidney Diseases C00004624
D008106 Liver Cirrhosis, Experimental C00004624
D056486 Drug-Induced Liver Injury C00004624
D006528 Carcinoma, Hepatocellular C00004624
D015431 Weight Loss C00004624
D003731 Dental Caries C00001063
D010510 Periodontal Diseases C00001063