KCF-S cluster No. 786 (11 metabolites)

Corresponding Phytochemical cluster No. 1

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	25
asterids	5
Liliopsida	5
eudicotyledons	1
Euphyllophyta	1

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Cumulative family count

class name	count
Fabaceae	12
Connaraceae	4
Moraceae	4
Euphorbiaceae	4
Hyacinthaceae	4
Campanulaceae	3
Bacillaceae	2
Streptomycetaceae	2
Solanaceae	2
Commelinaceae	1
Polygonaceae	1
Paenibacillaceae	1
Dryopteridaceae	1
Myrtaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Piperidine alkaloids	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Piperidine alkaloids	C10141	C00002035
Piperidine alkaloids	C10144	C00002038

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002035	1-Deoxymannojirimycin / (-)-Deoxymannojirimycin	CHEMBL11510 CHEMBL65131 CHEMBL307429 CHEMBL84844 CHEMBL110458 CHEMBL369297 CHEMBL179085 CHEMBL176206 CHEMBL179130 CHEMBL179347 CHEMBL179409 CHEMBL176021 CHEMBL369046 CHEMBL176209 CHEMBL368121 CHEMBL175901 CHEMBL1337303		33 / 27 / 27
C00002038	Fagomine	CHEMBL303545 CHEMBL108084 CHEMBL456583 CHEMBL505237 CHEMBL1818435 CHEMBL1818436 CHEMBL1818437 CHEMBL1818438 CHEMBL1818439	C105643	5 / 9 / 7
C00029420	1-Deoxynojirimycin / (+)-1-Deoxynojirimycin	CHEMBL11510 CHEMBL65131 CHEMBL307429 CHEMBL84844 CHEMBL110458 CHEMBL369297 CHEMBL179085 CHEMBL176206 CHEMBL179130 CHEMBL179347 CHEMBL179409 CHEMBL176021 CHEMBL369046 CHEMBL176209 CHEMBL368121 CHEMBL175901 CHEMBL1337303	D017485	33 / 27 / 27
C00036384	D-AB1 / 1,4-Dideoxy-1,4-imino-D-arabinitol	CHEMBL305131 CHEMBL80254 CHEMBL374349 CHEMBL261634 CHEMBL406973 CHEMBL1289018 CHEMBL1531321		13 / 12 / 9
C00036506	2R-Hydroxymethyl-3S-hydroxypyrrolidine / (+)-2R,3S)-2-(Hydroxymethyl)-3-hydroxypyrrolidine	CHEMBL408355		1 / 1 / 1
C00036613	6-Deoxy-fagomine / (-)-6-Deoxy-fagomine
C00042026	1,4-Dideoxyallonojirimycin / (-)-1,4-Dideoxyallonojirimycin	CHEMBL446497
C00042027	1,4-Dideoxyaltronojirimycin / (-)-1,4-Dideoxyaltronojirimycin	CHEMBL446497
C00042028	1,4-Dideoxymannojirimycin / (-)-1,4-Dideoxymannojirimycin	CHEMBL446497
C00049941	3,4-di-epi-fagomine / (-)-3,4-di-epi-fagomine	CHEMBL303545 CHEMBL108084 CHEMBL456583 CHEMBL505237 CHEMBL1818435 CHEMBL1818436 CHEMBL1818437 CHEMBL1818438 CHEMBL1818439		5 / 9 / 7
C00049947	3-epi-Fagomine	CHEMBL303545 CHEMBL108084 CHEMBL456583 CHEMBL505237 CHEMBL1818435 CHEMBL1818436 CHEMBL1818437 CHEMBL1818438 CHEMBL1818439		5 / 9 / 7

Human Protein / Gene in interactions

38 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04062	Glucosylceramidase	Enzyme	C00002035 C00002038 C00029420 C00036384 C00049941 C00049947	6 / 4
P04066	Tissue alpha-L-fucosidase	Enzyme	C00002035 C00002038 C00029420 C00049941 C00049947	1 / 2
Q9HCG7	Non-lysosomal glucosylceramidase	Enzyme	C00002035 C00002038 C00029420 C00049941 C00049947	1 / 0
Q14697	Neutral alpha-glucosidase AB	Enzyme	C00002035 C00002038 C00029420 C00049941 C00049947	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002035 C00002038 C00029420 C00049941 C00049947	1 / 1
P35573	Glycogen debranching enzyme	Enzyme	C00002035 C00029420 C00036384 C00036506	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002035 C00029420 C00036384	1 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002035 C00029420 C00036384	1 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002035 C00029420 C00036384	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002035 C00029420 C00036384	0 / 1
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00002035 C00029420 C00036384	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002035 C00029420 C00036384	0 / 1
Q6P4F1	Alpha-(1,3)-fucosyltransferase 10	Enzyme	C00002035 C00029420	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002035 C00029420	0 / 0
O00255	Menin	Unclassified protein	C00002035 C00029420	2 / 5
Q9Y2E5	Epididymis-specific alpha-mannosidase	Enzyme	C00002035 C00029420	0 / 0
P23458	Tyrosine-protein kinase JAK1	Jakb	C00002035 C00029420	0 / 0
P14410	Sucrase-isomaltase, intestinal	Enzyme	C00002035 C00029420	1 / 1
P06280	Alpha-galactosidase A	Enzyme	C00002035 C00029420	1 / 1
O00754	Lysosomal alpha-mannosidase	Enzyme	C00002035 C00029420	1 / 2
O00462	Beta-mannosidase	Enzyme	C00002035 C00029420	1 / 2
P16278	Beta-galactosidase	Enzyme	C00002035 C00029420	4 / 6
P10828	Thyroid hormone receptor beta	NR1A2	C00002035 C00029420	3 / 1
P55055	Oxysterols receptor LXR-beta	NR1H3	C00002035 C00029420	0 / 0
P09848	Lactase-phlorizin hydrolase	Enzyme	C00002035 C00029420	1 / 1
Q16739	Ceramide glucosyltransferase	Transferase	C00002035 C00029420	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002035 C00029420	0 / 0
Q9H227	Cytosolic beta-glucosidase	Enzyme	C00002035 C00029420	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002035 C00029420	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002035 C00029420	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002035 C00029420	1 / 2
O43280	Trehalase	Enzyme	C00002035 C00029420	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00002035 C00029420	0 / 0
P06737	Glycogen phosphorylase, liver form	Enzyme	C00036384	1 / 1
O75496	Geminin	Unclassified protein	C00036384	0 / 0
Q9UKM7	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	Enzyme	C00036384	1 / 0
Q16706	Alpha-mannosidase 2	Enzyme	C00036384	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00036384	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions