PCIDB

KNApSAcK Metabolite C00036384

Metabolite

KNApSAcK Entry

id C00036384
Name D-AB1 / 1,4-Dideoxy-1,4-imino-D-arabinitol
CAS RN 100937-52-8
Standard InChI InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2/t3-,4-,5-/m1/s1
Standard InChI (Main Layer) InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2

Cluster

Phytochemical cluster No. 1
KCF-S cluster No. 786

Link

ChEMBL

By standard InChI CHEMBL80254
By standard InChI Main Layer CHEMBL305131 CHEMBL80254 CHEMBL374349 CHEMBL261634 CHEMBL406973 CHEMBL1289018 CHEMBL1531321

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

13 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1531321 CHEMBL1741321 (1)
1 / 0
Q16706 Alpha-mannosidase 2 Enzyme CHEMBL261634 CHEMBL2215203 (1)
0 / 0
P04062 Glucosylceramidase Enzyme CHEMBL406973 CHEMBL2184144 (1)
6 / 4
P35573 Glycogen debranching enzyme Enzyme CHEMBL80254 CHEMBL374349 CHEMBL261634 CHEMBL406973 CHEMBL923883 (2) CHEMBL923884 (2)
CHEMBL982155 (1)
1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1531321 CHEMBL1741325 (1)
0 / 1
Q9UKM7 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Enzyme CHEMBL261634 CHEMBL2215204 (1)
1 / 0
O75496 Geminin Unclassified protein CHEMBL80254 CHEMBL2114780 (1)
0 / 0
P06737 Glycogen phosphorylase, liver form Enzyme CHEMBL80254 CHEMBL712597 (1)
1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1531321 CHEMBL1741322 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1531321 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1531321 CHEMBL1741324 (1)
0 / 1
O43451 Maltase-glucoamylase, intestinal Hydrolase CHEMBL80254 CHEMBL710106 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL80254 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232400 Glycogen storage disease iii P35573
#232700 Glycogen storage disease vi P06737
#614202 Mental retardation, autosomal recessive 15; mrt15 Q9UKM7
#168600 Parkinson disease, late-onset; pd P04062

KEGG DISEASE (9)

KEGG disease name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00069 Glycogen storage diseases (GSD) P06737 (related)
P35573 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)