Species

KNApSAcK Entry

Organism name Morus bombycis
Genus Morus
Family Moraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Morus bombycis
Linked NCBI taxonomy ID 66393
Linked level species

Family

Family in NCBI taxonomy Moraceae
ID 3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002405 External link 512 Mulberrofuran C
CHEMBL378806
CHEMBL505416
2 / 0 / 0 No. 81 No. 20
C00002893 External link 512 Oxyresveratrol
/ 2,3,4,5'-Tetrahydroxystilbene
CHEMBL43065
20 / 32 / 49 No. 295 No. 13
C00002038 External link 512 Fagomine
CHEMBL303545
CHEMBL108084
CHEMBL456583
CHEMBL505237
CHEMBL1818435
CHEMBL1818436
CHEMBL1818437
CHEMBL1818438
CHEMBL1818439
C105643
5 / 9 / 7 No. 786 No. 1
C00029420 External link 512 1-Deoxynojirimycin
/ (+)-1-Deoxynojirimycin
CHEMBL11510
CHEMBL65131
CHEMBL307429
CHEMBL84844
CHEMBL110458
CHEMBL369297
CHEMBL179085
CHEMBL176206
CHEMBL179130
CHEMBL179347
CHEMBL179409
CHEMBL176021
CHEMBL369046
CHEMBL176209
CHEMBL368121
CHEMBL175901
CHEMBL1337303
D017485
33 / 27 / 27 No. 786 No. 1
C00036384 External link 512 D-AB1
/ 1,4-Dideoxy-1,4-imino-D-arabinitol
CHEMBL305131
CHEMBL80254
CHEMBL374349
CHEMBL261634
CHEMBL406973
CHEMBL1289018
CHEMBL1531321
13 / 12 / 9 No. 786 No. 1

Human Protein / Gene in interactions

58 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04062 Glucosylceramidase Enzyme C00002038 C00029420 C00036384 6 / 4
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002893 C00029420 C00036384 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00029420 C00036384 1 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00029420 C00036384 1 / 1
O43451 Maltase-glucoamylase, intestinal Hydrolase C00029420 C00036384 0 / 0
Q9HCG7 Non-lysosomal glucosylceramidase Enzyme C00002038 C00029420 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00029420 C00036384 0 / 1
Q14697 Neutral alpha-glucosidase AB Enzyme C00002038 C00029420 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00002038 C00029420 1 / 1
P35573 Glycogen debranching enzyme Enzyme C00029420 C00036384 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00029420 C00036384 0 / 1
P04066 Tissue alpha-L-fucosidase Enzyme C00002038 C00029420 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002893 C00036384 1 / 1
P37840 Alpha-synuclein Unclassified protein C00002893 4 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00029420 3 / 1
P16278 Beta-galactosidase Enzyme C00029420 4 / 6
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00002893 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00002405 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002893 2 / 2
P39900 Macrophage metalloelastase M10A C00002893 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002893 0 / 0
P23458 Tyrosine-protein kinase JAK1 Jakb C00029420 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00029420 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00002893 2 / 2
Q9UKM7 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Enzyme C00036384 1 / 0
O75496 Geminin Unclassified protein C00036384 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00002893 4 / 2
P06737 Glycogen phosphorylase, liver form Enzyme C00036384 1 / 1
P14410 Sucrase-isomaltase, intestinal Enzyme C00029420 1 / 1
Q9H227 Cytosolic beta-glucosidase Enzyme C00029420 0 / 0
P14679 Tyrosinase Oxidoreductase C00002893 4 / 2
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00002893 4 / 4
P06280 Alpha-galactosidase A Enzyme C00029420 1 / 1
P45452 Collagenase 3 M10A C00002893 1 / 1
Q13133 Oxysterols receptor LXR-alpha NR1H3 C00029420 0 / 0
O00462 Beta-mannosidase Enzyme C00029420 1 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002893 0 / 3
P21728 D(1A) dopamine receptor Dopamine receptor C00029420 0 / 0
P08253 72 kDa type IV collagenase M10A C00002893 1 / 3
P55055 Oxysterols receptor LXR-beta NR1H3 C00029420 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002893 0 / 0
P09848 Lactase-phlorizin hydrolase Enzyme C00029420 1 / 1
Q16739 Ceramide glucosyltransferase Transferase C00029420 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00029420 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002893 7 / 37
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00002405 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002893 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00029420 0 / 0
Q16706 Alpha-mannosidase 2 Enzyme C00036384 0 / 0
O43280 Trehalase Enzyme C00029420 0 / 0
P08254 Stromelysin-1 M10A C00002893 1 / 0
O00754 Lysosomal alpha-mannosidase Enzyme C00029420 1 / 2
Q6P4F1 Alpha-(1,3)-fucosyltransferase 10 Enzyme C00029420 0 / 0
Q9Y2E5 Epididymis-specific alpha-mannosidase Enzyme C00029420 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002893 1 / 0
O00255 Menin Unclassified protein C00029420 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00029420 1 / 2
P03956 Interstitial collagenase M10A C00002893 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (60)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#133239 Esophageal cancer P04637
#301500 Fabry disease P06280
#230000 Fucosidosis P04066
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#232400 Glycogen storage disease iii P35573
#232700 Glycogen storage disease vi P06737
#230500 Gm1-gangliosidosis, type i P16278
#230600 Gm1-gangliosidosis, type ii P16278
#230650 Gm1-gangliosidosis, type iii P16278
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603932 Intervertebral disc disease; idd P14780
#223000 Lactase deficiency, congenital P09848
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#248500 Mannosidosis, alpha b, lysosomal; mansa O00754
#248510 Mannosidosis, beta a, lysosomal; mansb O00462
#614202 Mental retardation, autosomal recessive 15; mrt15 Q9UKM7
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#253010 Mucopolysaccharidosis type ivb P16278
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P04062
P37840
#604229 Peters anomaly Q16678
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#614409 Spastic paraplegia 46, autosomal recessive; spg46 Q9HCG7
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#222900 Sucrase-isomaltase deficiency, congenital; csid P14410
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (73)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00140 beta-Mannosidosis O00462 (related)
H00422 Glycoproteinoses O00462 (related)
O00754 (related)
P04066 (related)
P16278 (related)
H00139 alpha-Mannosidosis O00754 (related)
H00028 Choriocarcinoma P03956 (related)
P04637 (related)
P08253 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
P37840 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
P16278 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00141 Fucosidosis P04066 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P06737 (related)
P10253 (related)
P35573 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00116 Congenital lactase deficiency P09848 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00115 Congenital sucrase-isomaltase deficiency P14410 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00123 Mucopolysaccharidosis type IV (MPS4) P16278 (related)
H00276 Galactosialidosis P16278 (related)
H00281 GM1 gangliosidosis P16278 (related)
H00421 Mucopolysaccharidosis (MPS) P16278 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)