KCF-S cluster No. 190 (32 metabolites)

Corresponding Phytochemical cluster No. 13

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (32)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
rosids	45
asterids	3
Liliopsida	1

---

Cumulative family count

class name	count
Fabaceae	23
Moraceae	20
Cannabaceae	2
Asteraceae	2
Apiaceae	1
Zingiberaceae	1

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Chalcones	1

---

metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Chalcones	C08573	C00002371

Metabolite list (32)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002371	Abyssinone VI	CHEMBL508727		1 / 0 / 0
C00007007	Glyinflanin A
C00007010	Glyinflanin E
C00007054	Spinochalcone A
C00007072	Kanzonol C / 2',4',4-Trihydroxy-3'-prenylchalcone	CHEMBL1644933
C00007073	4,2',4'-Trihydroxy-3',5'-diprenylchalcone	CHEMBL403930
C00007113	Antiarone E
C00007115	Antiarone D
C00007116	Antiarone C
C00007122	Flemiwallichin E
C00007124	Xanthoangelol	CHEMBL494083 CHEMBL457210	C068244	20 / 30 / 25	1 / 0
C00007128	3'-Geranyl-2',4',6'-trihydroxychalcone
C00007137	Kuwanol D
C00007138	Ammothamnidin
C00007139	Kushenol D
C00007142	5-Deoxyhomoflemingin
C00007148	Kuraridin	CHEMBL243362		3 / 2 / 2
C00007149	Kuraridinol
C00007151	Flemiwallichin C
C00007155	Homoflemingin
C00011136	Bartericin D
C00011138	Angusticornin B / 3,5'-di-(2-Hydroxy-3-methylbut-3-enyl)-4,2',4'-trihydroxychalcone
C00011140	Stipulin	CHEMBL1169874
C00011141	Bartericin A	CHEMBL1169613
C00014441	3'-Neryl-2',4',6'-trihydroxychalcone
C00014454	Paratocarpin D / 3'-Prenyl-3-(2-hydroxy-3-methylbutyl-3-enyl)-4,2',4'-trihydroxychalcone
C00014455	Paratocarpin E / 3-Prenyl-3'-(2-hydroxy-3-methylbutyl-3-enyl)-4,2',4'-trihydroxychalcone
C00014457	Anthyllin / 5-Prenyl-3-(2-hydroxy-3-methylbutyl-3-enyl)-4,2',4'-trihydroxychalcone
C00014471	3'-Geranylchalconaringenin / 3'-Geranyl-4,2',4',6'-tetrahydroxychalcone	CHEMBL480722
C00014473	5'-Prenylxanthohumol / 3',5'-Diprenyl-4,2',4'-trihydroxy-6-methoxychalcone	CHEMBL471777
C00014484	3'-Geranyl-3,4,2',4'-tetrahydroxychalcone	CHEMBL258707
C00038202	2',4'-Dihydroxy-3'-(1''-geranyl)-6'-methoxychalcone	CHEMBL255070

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002371	0 / 0
P13866	Sodium/glucose cotransporter 1	Glucose	C00007148	1 / 1
P31639	Sodium/glucose cotransporter 2	Glucose	C00007148	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00007124	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00007124	1 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00007124	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00007124	11 / 10
P37840	Alpha-synuclein	Unclassified protein	C00007124	4 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00007124	1 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00007148	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00007124	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00007124	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00007124	2 / 0
O75496	Geminin	Unclassified protein	C00007124	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00007124	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00007124	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00007124	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00007124	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00007124	4 / 3
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00007124	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00007124	1 / 0
O00255	Menin	Unclassified protein	C00007124	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00007124	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00007124	1 / 1

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00007124

Related Diseases

Diseases related to proteins in ChEMBL interactions