Species

KNApSAcK Entry

Organism name Artocarpus fretessi
Genus Artocarpus
Family Moraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Artocarpus
Linked NCBI taxonomy ID 3488
Linked level genus

Family

Family in NCBI taxonomy Moraceae
ID 3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00013421 External link 512 Heteroartonin A
/ 2-[2,5-Dihydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-5,7-dihydroxy-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
No. 14 No. 15
C00004028 External link 512 Mulberrin
/ Kuwanon C
/ Norartocarpin
/ 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CHEMBL518543
3 / 0 / 3 No. 14 No. 15
C00001070 External link 512 Morusin
/ Mulberrochromene
/ 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
CHEMBL464006
C057451
16 / 17 / 10 No. 18 No. 15
C00019247 External link 512 Artoindonesianin Y
/ 3',5'-Dihydroxy-2',6'-diprenyl-6'',6''-dimethylpyrano[2'',3'':6,7]-2-arylbenzofuran
No. 18 No. 15
C00003859 External link 512 Norartocarpetin
CHEMBL463145
3 / 0 / 3 No. 71 No. 15
C00019246 External link 512 Artoindonesianin X
/ 6,3',5'-Trihydroxy-7,2',6'-triprenyl-2-arylbenzofuran
No. 319 No. 15

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001070 C00003859 C00004028 0 / 3
P56817 Beta-secretase 1 A1A C00001070 C00003859 C00004028 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001070 C00003859 C00004028 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001070 0 / 0
P37840 Alpha-synuclein Unclassified protein C00001070 4 / 2
Q99700 Ataxin-2 Unclassified protein C00001070 1 / 1
P39748 Flap endonuclease 1 Enzyme C00001070 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001070 2 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001070 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001070 7 / 3
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001070 2 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00001070 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001070 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001070 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001070 1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001070 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P18054
P84022
#127750 Dementia, lewy body; dlb P37840
#133239 Esophageal cancer P18054
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (10)

KEGG name UniProt
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)