KNApSAcK Metabolite C00001040
Metabolite
KNApSAcK Entry
| id | C00001040 |
|---|---|
| Name | Flavone |
| CAS RN | 525-82-6 |
| Standard InChI | InChI=1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H |
| Standard InChI (Main Layer) | InChI=1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H |
Cluster
| Phytochemical cluster | No. 15 |
|---|---|
| KCF-S cluster | No. 76 |
Link
ChEMBL
| By standard InChI | CHEMBL275638 |
|---|---|
| By standard InChI Main Layer | CHEMBL275638 |
KEGG
| By LinkDB | C10043 |
|---|
CTD
| By CAS RN | C043562 |
|---|
Species
Summary
Family
| family name | count |
|---|---|
| Primulaceae | 2 |
| Thymelaeaceae | 2 |
| Myrtaceae | 1 |
List (5)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Dionysia spp. | 175032 | Primulaceae | asterids | Viridiplantae |
| Feijoa sellowiana | 260130 | Myrtaceae | rosids | Viridiplantae |
| Pimelea decora | 586301 | Thymelaeaceae | rosids | Viridiplantae |
| Pimelea simplex | 746341 | Thymelaeaceae | rosids | Viridiplantae |
| Primula spp. | 49647 | Primulaceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
58 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | CHEMBL275638 |
CHEMBL957998
(1)
CHEMBL957999
(1)
|
0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | CHEMBL275638 |
CHEMBL1613995
(1)
|
7 / 44 |
| Q16637 | Survival motor neuron protein | Unclassified protein | CHEMBL275638 |
CHEMBL1613842
(1)
|
4 / 2 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | CHEMBL275638 |
CHEMBL1071598
(1)
|
0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | CHEMBL275638 |
CHEMBL638578
(1)
CHEMBL641515
(1)
CHEMBL649050 (1) |
0 / 0 |
| P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | CHEMBL275638 |
CHEMBL827974
(1)
|
0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | CHEMBL275638 |
CHEMBL1794552
(1)
|
0 / 0 |
| P62158 | Calmodulin | Unclassified protein | CHEMBL275638 |
CHEMBL1647727
(2)
CHEMBL1647728
(1)
|
1 / 0 |
| O95271 | Tankyrase-1 | Enzyme | CHEMBL275638 |
CHEMBL2341188
(2)
|
0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | CHEMBL275638 |
CHEMBL1794561
(1)
|
3 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | CHEMBL275638 |
CHEMBL1794371
(1)
CHEMBL1794471
(1)
|
0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | CHEMBL275638 |
CHEMBL2019838
(1)
CHEMBL2019839
(1)
|
1 / 2 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | CHEMBL275638 |
CHEMBL1071594
(1)
|
1 / 1 |
| P08183 | Multidrug resistance protein 1 | drug | CHEMBL275638 |
CHEMBL1827948
(1)
|
1 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL275638 |
CHEMBL941404
(1)
|
1 / 11 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | CHEMBL275638 |
CHEMBL1014691
(1)
|
0 / 0 |
| P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Enzyme | CHEMBL275638 |
CHEMBL1168908
(1)
|
1 / 1 |
| O43570 | Carbonic anhydrase 12 | Lyase | CHEMBL275638 |
CHEMBL2019842
(1)
CHEMBL2019843
(1)
|
1 / 2 |
| O75496 | Geminin | Unclassified protein | CHEMBL275638 |
CHEMBL2114843
(1)
CHEMBL2114780
(1)
|
0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | CHEMBL275638 |
CHEMBL1613838
(1)
|
0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | CHEMBL275638 |
CHEMBL2114835
(1)
|
0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | CHEMBL275638 |
CHEMBL2019836
(1)
CHEMBL2019837
(1)
|
0 / 0 |
| P09874 | Poly [ADP-ribose] polymerase 1 | Enzyme | CHEMBL275638 |
CHEMBL2341185
(2)
|
0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL275638 |
CHEMBL2114788
(1)
CHEMBL2114931
(1)
|
0 / 0 |
| Q12791 | Calcium-activated potassium channel subunit alpha-1 | KCNM, KCa1.x | CHEMBL275638 |
CHEMBL767233
(1)
|
1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL275638 |
CHEMBL1794401
(1)
|
0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | CHEMBL275638 |
CHEMBL1052488
(1)
CHEMBL1052489
(1)
CHEMBL1794382 (2) |
0 / 1 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | CHEMBL275638 |
CHEMBL1105634
(1)
|
2 / 2 |
| Q16790 | Carbonic anhydrase 9 | Lyase | CHEMBL275638 |
CHEMBL2019840
(1)
CHEMBL2019841
(1)
|
0 / 1 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | CHEMBL275638 |
CHEMBL1687393
(1)
CHEMBL1687394
(1)
|
2 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | CHEMBL275638 |
CHEMBL1614038
(1)
|
2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | CHEMBL275638 |
CHEMBL1614342
(1)
|
1 / 1 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | CHEMBL275638 |
CHEMBL2114842
(1)
|
0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL275638 |
CHEMBL1738588
(1)
CHEMBL1738317
(1)
|
0 / 0 |
| Q9H2K2 | Tankyrase-2 | Enzyme | CHEMBL275638 |
CHEMBL2341186
(2)
|
0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | CHEMBL275638 |
CHEMBL1794364
(1)
|
1 / 1 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | CHEMBL275638 |
CHEMBL958788
(1)
CHEMBL958789
(1)
|
0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL275638 |
CHEMBL1614108
(1)
CHEMBL1613886
(1)
|
0 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL275638 |
CHEMBL2114890
(2)
CHEMBL2114908
(1)
|
0 / 0 |
| P10275 | Androgen receptor | NR3C4 | CHEMBL275638 |
CHEMBL1052486
(1)
CHEMBL1052487
(1)
CHEMBL1052490 (2) |
3 / 4 |
| P15144 | Aminopeptidase N | M1 | CHEMBL275638 |
CHEMBL646405
(1)
|
0 / 1 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | CHEMBL275638 |
CHEMBL2114849
(2)
|
0 / 0 |
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
1 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
1 / 1 |
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
1 / 1 |
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
4 / 2 |
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
0 / 0 |
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | CHEMBL275638 |
CHEMBL652513
(1)
CHEMBL877825
(1)
|
1 / 0 |
CTD interaction (26)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C043562 | 4363 |
ABCC1
ABC29 ABCC GS-X MRP MRP1 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | flavone inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione] |
affects export
/ decreases reaction |
protein |
15041478
|
| C043562 | 4363 |
ABCC1
ABC29 ABCC GS-X MRP MRP1 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | flavone results in decreased activity of ABCC1 protein |
decreases activity
|
protein |
15041478
|
| C043562 | 9429 |
ABCG2
ABC15 ABCP BCRP BCRP1 BMDP CD338 CDw338 EST157481 GOUT1 MRX MXR MXR1 UAQTL1 |
ATP-binding cassette, sub-family G (WHITE), member 2 | flavone results in increased expression of ABCG2 mRNA |
increases expression
|
mRNA |
17077187
|
| C043562 | 9429 |
ABCG2
ABC15 ABCP BCRP BCRP1 BMDP CD338 CDw338 EST157481 GOUT1 MRX MXR MXR1 UAQTL1 |
ATP-binding cassette, sub-family G (WHITE), member 2 | flavone results in increased expression of ABCG2 protein |
increases expression
|
protein |
17077187
|
| C043562 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | flavone binds to AHR protein |
affects binding
|
protein |
20436506
|
| C043562 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | flavone results in increased activity of CASP3 protein |
increases activity
|
protein |
15800915
|
| C043562 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Melatonin promotes the reaction [flavone results in increased activity of CASP3 protein] |
increases activity
/ increases reaction |
protein |
15800915
|
| C043562 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | flavone results in increased activity of CYP19A1 protein |
increases activity
|
protein |
15319488
|
| C043562 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | flavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
17090139
|
| C043562 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | flavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] |
decreases reaction
/ increases expression |
protein |
17090139
|
| C043562 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | flavone results in decreased activity of CYP1A1 protein |
decreases activity
|
protein |
21053930
|
| C043562 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | flavone results in increased expression of CYP1A1 mRNA |
increases expression
|
mRNA |
15890477
|
| C043562 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | flavone results in increased expression of CYP1A1 protein |
increases expression
|
protein |
15890477
|
| C043562 | 1544 |
CYP1A2
CP12 P3-450 P450(PA) |
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | flavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
17090139
|
| C043562 | 1544 |
CYP1A2
CP12 P3-450 P450(PA) |
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | flavone results in decreased activity of CYP1A2 protein |
decreases activity
|
protein |
21053930
|
| C043562 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | flavone binds to and results in decreased activity of CYP1B1 protein |
affects binding
/ decreases activity |
protein |
19563207
21053930 |
| C043562 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | flavone results in increased expression of CYP1B1 mRNA |
increases expression
|
mRNA |
15890477
|
| C043562 | 1559 |
CYP2C9
CPC9 CYP2C CYP2C10 CYPIIC9 P450IIC9 |
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | flavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] |
decreases reaction
/ increases hydroxylation |
protein |
21053930
|
| C043562 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | flavone binds to and results in decreased activity of CYP3A4 protein |
affects binding
/ decreases activity |
protein |
21053930
|
| C043562 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | flavone inhibits the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 4-hydroxymidazolam] |
decreases reaction
/ increases chemical synthesis / increases oxidation |
protein |
21053930
|
| C043562 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | flavone promotes the reaction [[CYP3A4 protein results in increased oxidation of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam] |
increases chemical synthesis
/ increases oxidation / increases reaction |
protein |
21053930
|
| C043562 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | flavone binds to ESR2 protein |
affects binding
|
protein |
12224631
|
| C043562 | 2101 |
ESRRA
ERR1 ERRa ERRalpha ESRL1 NR3B1 |
estrogen-related receptor alpha | flavone binds to and results in increased activity of ESRRA protein |
affects binding
/ increases activity |
protein |
14638870
|
| C043562 | 2101 |
ESRRA
ERR1 ERRa ERRalpha ESRL1 NR3B1 |
estrogen-related receptor alpha | flavone binds to ESRRA protein mutant form |
affects binding
|
protein |
14638870
|
| C043562 | 2103 |
ESRRB
DFNB35 ERR2 ERRb ESRL2 NR3B2 |
estrogen-related receptor beta | flavone binds to and results in increased activity of ESRRB protein |
affects binding
/ increases activity |
protein |
14638870
|
| C043562 | 5444 |
PON1
ESA MVCD5 PON |
paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) | flavone results in increased expression of PON1 mRNA |
increases expression
|
mRNA |
15169886
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (40)
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P47869
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #300615 | Brunner syndrome |
P21397
|
| #604931 | Cortisone reductase deficiency 1; cortrd1 |
P28845
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P18507
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #609446 | Generalized epilepsy and paroxysmal dyskinesia; gepd |
Q12791
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P00533
P04637 |
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #614916 | Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 |
P62158
|
KEGG DISEASE (58)
| KEGG | disease name | UniProt |
|---|---|---|
| H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) |
| H00018 | Gastric cancer |
P00533
(related)
P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00003 | Acute myeloid leukemia (AML) |
P15144
(marker)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01111 | Cortisone reductase deficiency (CRD) |
P28845
(related)
|
| H01258 | Generalized epilepsy and paroxysmal dyskinesia (GEPD) |
Q12791
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
Q16637 (related) |