Species

KNApSAcK Entry

Organism name Feijoa sellowiana
Genus Feijoa
Family Myrtaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Acca sellowiana
Linked NCBI taxonomy ID 260130
Linked level species

Family

Family in NCBI taxonomy Myrtaceae
ID 3931

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000919 External link 512 beta-Carotene
CHEMBL1293
CHEMBL1966639
D019207
7 / 12 / 11 104 / 19 No. 26 No. 59
C00003674 External link 512 Stigmasterol
/ beta-Stigmasterol
CHEMBL66943
CHEMBL186373
CHEMBL400247
CHEMBL1568947
D013265
5 / 0 / 0 1 / 0 No. 53 No. 11
C00001040 External link 512 Flavone
CHEMBL275638
C043562
58 / 40 / 58 14 / 0 No. 76 No. 15
C00002910 External link 512 Casuarinin
CHEMBL79244
CHEMBL507387
11 / 2 / 2 No. 226 No. 81
C00002938 External link 512 Tellimagrandin I
CHEMBL450376
C087926
7 / 0 No. 302 No. 81
C00007366 External link 512 alpha-Tocopherol
CHEMBL47
CHEMBL49563
CHEMBL442800
D024502
99 / 57 / 52 54 / 55 No. 1290

Human Protein / Gene in interactions

165 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P33765 Adenosine receptor A3 Adenosine receptor C00001040 C00007366 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001040 C00007366 0 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00000919 C00007366 1 / 0
P03372 Estrogen receptor NR3A1 C00001040 C00007366 1 / 1
P04150 Glucocorticoid receptor NR3C1 C00001040 C00007366 0 / 1
O75496 Geminin Unclassified protein C00000919 C00001040 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00001040 C00003674 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00001040 C00007366 1 / 8
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00000919 C00007366 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00001040 C00007366 1 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00000919 C00007366 0 / 1
P00918 Carbonic anhydrase 2 Lyase C00001040 C00007366 1 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00001040 C00007366 3 / 1
P02545 Prelamin-A/C Unclassified protein C00000919 C00007366 11 / 10
P17252 Protein kinase C alpha type Alpha C00002910 C00007366 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00007366 4 / 3
P27361 Mitogen-activated protein kinase 3 Erk C00007366 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00001040 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00007366 2 / 2
P62158 Calmodulin Unclassified protein C00001040 1 / 0
O95271 Tankyrase-1 Enzyme C00001040 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00007366 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00007366 0 / 0
P06746 DNA polymerase beta Enzyme C00003674 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00001040 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00007366 0 / 0
P78527 DNA-dependent protein kinase catalytic subunit Atypical serine/threonine protein kinase PIKK subfamily C00001040 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00007366 1 / 0
P25021 Histamine H2 receptor Histamine receptor C00007366 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00007366 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00007366 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00007366 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00007366 0 / 0
P08246 Neutrophil elastase S1A C00007366 2 / 1
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00003674 0 / 0
P08183 Multidrug resistance protein 1 drug C00001040 1 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00007366 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00007366 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00007366 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00007366 0 / 1
P16662 UDP-glucuronosyltransferase 2B7 Enzyme C00007366 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00007366 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00007366 0 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00007366 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00007366 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00007366 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00007366 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00007366 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00007366 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00007366 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00007366 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00007366 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00007366 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00000919 0 / 0
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme C00001040 1 / 1
O43570 Carbonic anhydrase 12 Lyase C00001040 1 / 2
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00007366 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00000919 0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00001040 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00001040 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00007366 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00007366 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00007366 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00007366 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00007366 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00007366 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00007366 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00007366 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00007366 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00007366 0 / 0
P10145 Interleukin-8 Secreted protein C00001040 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00007366 1 / 0
P00915 Carbonic anhydrase 1 Lyase C00001040 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00007366 0 / 0
P08311 Cathepsin G S1A C00007366 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00007366 1 / 0
P09874 Poly [ADP-ribose] polymerase 1 Enzyme C00001040 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001040 0 / 0
Q12791 Calcium-activated potassium channel subunit alpha-1 KCNM, KCa1.x C00001040 1 / 1
P03956 Interstitial collagenase M10A C00007366 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00007366 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001040 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00007366 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00007366 0 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00007366 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00007366 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00001040 2 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00007366 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00007366 2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00007366 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00007366 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00007366 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00007366 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00007366 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00007366 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00007366 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00007366 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00007366 2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00007366 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00001040 0 / 1
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001040 2 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001040 2 / 2
O15118 Niemann-Pick C1 protein Unclassified protein C00001040 1 / 1
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00001040 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001040 0 / 0
Q9H2K2 Tankyrase-2 Enzyme C00001040 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00007366 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001040 4 / 1
P04637 Cellular tumor antigen p53 Transcription Factor C00001040 7 / 37
P09884 DNA polymerase alpha catalytic subunit Transferase C00003674 0 / 0
P22303 Acetylcholinesterase Hydrolase C00007366 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00007366 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00007366 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00007366 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00007366 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00007366 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00007366 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00007366 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00007366 1 / 1
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme C00001040 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00001040 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00007366 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00007366 0 / 0
P29466 Caspase-1 C14 C00007366 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001040 0 / 0
P10275 Androgen receptor NR3C4 C00001040 3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00007366 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00007366 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00007366 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00007366 0 / 0
P15144 Aminopeptidase N M1 C00001040 0 / 1
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00007366 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00007366 0 / 1
P35869 Aryl hydrocarbon receptor Transcription Factor C00001040 0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00007366 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00007366 0 / 0
O00255 Menin Unclassified protein C00007366 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00007366 1 / 2
Q05513 Protein kinase C zeta type Iota C00002910 0 / 0
Q04759 Protein kinase C theta type Delta C00002910 0 / 1
Q02156 Protein kinase C epsilon type Eta C00002910 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00002910 0 / 0
Q05655 Protein kinase C delta type Delta C00002910 0 / 0
P05129 Protein kinase C gamma type Alpha C00002910 1 / 1
P05771 Protein kinase C beta type Alpha C00002910 0 / 0
P24723 Protein kinase C eta type Eta C00002910 1 / 0
P41743 Protein kinase C iota type Iota C00002910 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00002910 0 / 0
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00001040 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00001040 1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00001040 1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00001040 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00001040 1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00001040 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00001040 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00001040 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00001040 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00001040 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00001040 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00001040 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00001040 4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00001040 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00001040 0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00001040 1 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00003674 0 / 0

168 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000919 C00001040 C00007366
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000919 C00007366
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00000919 C00007366
6256 RXRA, NR2B1 retinoid X receptor, alpha C00000919 C00007366
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000919 C00007366
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000919 C00007366
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00000919 C00007366
581 BAX, BCL2L4 BCL2-associated X protein C00000919 C00007366
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00000919 C00001040
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00000919 C00001040
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00000919 C00001040
23621 BACE1, ASP2, BACE, HSPC104 beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) C00007366
2103 ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2 estrogen-related receptor beta C00001040
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00001040
43 ACHE, ACEE, ARACHE, N-ACHE, YT acetylcholinesterase (EC:3.1.1.7) C00002938
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00002938
2624 GATA2, DCML, MONOMAC, NFE1B GATA binding protein 2 C00002938
2993 GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 glycophorin A (MNS blood group) C00002938
3145 HMBS, PBG-D, PBGD, PORC, UPS hydroxymethylbilane synthase (EC:2.5.1.61) C00002938
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) C00002938
4778 NFE2, NF-E2, p45 nuclear factor, erythroid 2 C00002938
10599 SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family, member 1B1 C00003674
124 ADH1A, ADH1 alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1) C00000919
128 ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) C00000919
221 ALDH3B1, ALDH4, ALDH7 aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5) C00000919
8659 ALDH4A1, ALDH4, P5CD, P5CDh aldehyde dehydrogenase 4 family, member A1 (EC:1.2.1.88) C00000919
287 ANK2, ANK-2, LQT4, brank-2 ankyrin 2, neuronal C00000919
288 ANK3, ANKYRIN-G, MRT37 ankyrin 3, node of Ranvier (ankyrin G) C00000919
427 ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23) C00000919
51665 ASB1, ASB-1 ankyrin repeat and SOCS box containing 1 C00000919
140462 ASB9 ankyrin repeat and SOCS box containing 9 C00000919
9531 BAG3, BAG-3, BIS, CAIR-1, MFM6 BCL2-associated athanogene 3 C00000919
9530 BAG4, BAG-4, SODD BCL2-associated athanogene 4 C00000919
9529 BAG5, BAG-5 BCL2-associated athanogene 5 C00000919
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001040
53630 BCMO1, BCDO, BCDO1, BCMO, BCO, BCO1 beta-carotene 15,15'-monooxygenase 1 (EC:1.14.99.36) C00000919
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00000919
8837 CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS CASP8 and FADD-like apoptosis regulator C00000919
9071 CLDN10, CPETRL3, OSP-L claudin 10 C00000919
51208 CLDN18, SFTA5, SFTPJ claudin 18 C00000919
1277 COL1A1, OI4 collagen, type I, alpha 1 C00000919
1282 COL4A1, HANAC, ICH, POREN1, arresten collagen, type IV, alpha 1 C00000919
1284 COL4A2, ICH, POREN2 collagen, type IV, alpha 2 C00000919
8738 CRADD, MRT34, RAIDD CASP2 and RIPK1 domain containing adaptor with death domain C00000919
1508 CTSB, APPS, CPSB cathepsin B (EC:3.4.22.1) C00000919
6387 CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B chemokine (C-X-C motif) ligand 12 C00000919
6372 CXCL6, CKA-3, GCP-2, GCP2, SCYB6 chemokine (C-X-C motif) ligand 6 C00000919
4283 CXCL9, CMK, Humig, MIG, SCYB9, crg-10 chemokine (C-X-C motif) ligand 9 C00000919
7852 CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM chemokine (C-X-C motif) receptor 4 C00000919
1592 CYP26A1, CP26, CYP26, P450RAI, P450RAI1 cytochrome P450, family 26, subfamily A, polypeptide 1 (EC:1.14.-.-) C00000919
64816 CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 (EC:1.14.14.1) C00000919
1746 DLX2, TES-1, TES1 distal-less homeobox 2 C00000919
1748 DLX4, BP1, DLX7, DLX8, DLX9 distal-less homeobox 4 C00000919
2068 ERCC2, COFS2, EM9, TTD, XPD excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12) C00000919
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00000919
23017 FAIM2, LFG, LFG2, NGP35, NMP35, TMBIM2 Fas apoptotic inhibitory molecule 2 C00000919
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00000919
3169 FOXA1, HNF3A, TCF3A forkhead box A1 C00000919
2627 GATA6 GATA binding protein 6 C00000919
2633 GBP1 guanylate binding protein 1, interferon-inducible C00000919
81025 GJA9, CX58, CX59, GJA10 gap junction protein, alpha 9, 59kDa C00000919
373156 GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1 glutathione S-transferase kappa 1 (EC:2.5.1.18) C00000919
2946 GSTM2, GST4, GSTM, GSTM2-2, GTHMUS glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18) C00000919
2948 GSTM4, GSTM4-4, GTM4 glutathione S-transferase mu 4 (EC:2.5.1.18) C00000919
2949 GSTM5, GSTM5-5, GTM5 glutathione S-transferase mu 5 (EC:2.5.1.18) C00000919
2954 GSTZ1, GSTZ1-1, MAAI, MAI glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2) C00000919
3204 HOXA7, ANTP, HOX1, HOX1.1, HOX1A homeobox A7 C00000919
3216 HOXB6, HOX2, HOX2B, HU-2, Hox-2.2 homeobox B6 C00000919
3226 HOXC10, HOX3I homeobox C10 C00000919
3448 IFNA14, IFN-alphaH, LEIF2H interferon, alpha 14 C00000919
3449 IFNA16, IFN-alphaO interferon, alpha 16 C00000919
3451 IFNA17, IFN-alphaI, IFNA, INFA, LEIF2C1 interferon, alpha 17 C00000919
3442 IFNA5, IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF_G interferon, alpha 5 C00000919
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000919
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001040
3394 IRF8, H-ICSBP, ICSBP, ICSBP1, IRF-8 interferon regulatory factor 8 C00000919
50805 IRX4, IRXA3 iroquois homeobox 4 C00000919
3688 ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) C00000919
3691 ITGB4, CD104 integrin, beta 4 C00000919
3713 IVL involucrin C00000919
3875 KRT18, CYK18, K18 keratin 18 C00000919
3880 KRT19, CK19, K19, K1CS keratin 19 C00000919
3849 KRT2, CK-2e, K2e, KRT2A, KRT2E, KRTE keratin 2 C00000919
3855 KRT7, CK7, K2C7, K7, SCL keratin 7 C00000919
3856 KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO keratin 8 C00000919
8022 LHX3, CPHD3, LIM3, M2-LHX3 LIM homeobox 3 C00000919
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001040
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001040
4153 MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD mannose-binding lectin (protein C) 2, soluble C00000919
4170 MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT myeloid cell leukemia sequence 1 (BCL2-related) C00000919
4212 MEIS2, HsT18361, MRG1 Meis homeobox 2 C00000919
4222 MEOX1, KFS2, MOX1 mesenchyme homeobox 1 C00000919
4255 MGMT O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) C00000919
3110 MNX1, HB9, HLXB9, HOXHB9, SCRA1 motor neuron and pancreas homeobox 1 C00000919
4439 MSH5, G7, MUTSH5, NG23 mutS homolog 5 C00000919
4586 MUC5AC, MUC5, TBM, leB mucin 5AC, oligomeric mucus/gel-forming C00000919
4842 NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) C00000919
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00000919
4973 OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 oxidized low density lipoprotein (lectin-like) receptor 1 C00000919
5098 PCDHGC3, PC43, PCDH-GAMMA-C3, PCDH2 protocadherin gamma subfamily C, 3 C00000919
5359 PLSCR1, MMTRA1B phospholipid scramblase 1 C00000919
57048 PLSCR3 phospholipid scramblase 3 C00000919
57088 PLSCR4, TRA1 phospholipid scramblase 4 C00000919
10635 RAD51AP1, PIR51 RAD51 associated protein 1 C00000919
5892 RAD51D, BROVCA4, R51H3, RAD51L3, TRAD RAD51 paralog D C00000919
5914 RARA, NR1B1, RAR retinoic acid receptor, alpha C00000919
5915 RARB, HAP, NR1B2, RRB2 retinoic acid receptor, beta C00000919
5918 RARRES1, LXNL, TIG1 retinoic acid receptor responder (tazarotene induced) 1 C00000919
5950 RBP4, RDCCAS retinol binding protein 4, plasma C00000919
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001040
949 SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1 scavenger receptor class B, member 1 C00000919
4990 SIX6, MCOPCT2, OPTX2, Six9 SIX homeobox 6 C00000919
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001040
9517 SPTLC2, HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a serine palmitoyltransferase, long chain base subunit 2 (EC:2.3.1.50) C00000919
6720 SREBF1, SREBP-1c, SREBP1, bHLHd1 sterol regulatory element binding transcription factor 1 C00000919
7052 TGM2, G-ALPHA-h, GNAH, TG2, TGC transglutaminase 2 (EC:2.3.2.13) C00000919
7047 TGM4, TGP, hTGP transglutaminase 4 (EC:2.3.2.13) C00000919
9429 ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 ATP-binding cassette, sub-family G (WHITE), member 2 C00001040
3604 TNFRSF9, 4-1BB, CD137, CDw137, ILA tumor necrosis factor receptor superfamily, member 9 C00000919
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00000919
10190 TXNDC9, APACD, PHLP3 thioredoxin domain containing 9 C00000919
7517 XRCC3, CMM6 X-ray repair complementing defective repair in Chinese hamster cells 3 C00000919
335 APOA1 apolipoprotein A-I C00007366
338 APOB, FLDB, LDLCQ4 apolipoprotein B C00007366
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00007366
1386 ATF2, CRE-BP1, CREB2, HB16, TREB7 activating transcription factor 2 (EC:2.3.1.48) C00007366
2101 ESRRA, ERR1, ERRa, ERRalpha, ESRL1, NR3B1 estrogen-related receptor alpha C00001040
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00007366
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00007366
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00007366
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00007366
847 CAT catalase (EC:1.11.1.6) C00007366
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00007366
1382 CRABP2, CRABP-II, RBP6 cellular retinoic acid binding protein 2 C00007366
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00007366
1649 DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 DNA-damage-inducible transcript 3 C00007366
83939 EIF2A, EIF-2A, MST089, MSTP004, MSTP089 eukaryotic translation initiation factor 2A, 65kDa C00007366
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00007366
2534 FYN, SLK, SYN, p59-FYN FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2) C00007366
2879 GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx glutathione peroxidase 4 (EC:1.11.1.12) C00007366
3048 HBG2, TNCY hemoglobin, gamma G C00007366
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00007366
3240 HP, BP, HP2ALPHA2, HPA1S haptoglobin C00007366
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00007366
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00007366
3932 LCK, LSK, YT16, p56lck, pp58lck lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) C00007366
4067 LYN, JTK8, p53Lyn, p56Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) C00007366
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00007366
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00007366
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00007366
4155 MBP myelin basic protein C00007366
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00007366
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00007366
11315 PARK7, DJ-1, DJ1 parkinson protein 7 C00007366
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00007366
5230 PGK1, MIG10, PGKA phosphoglycerate kinase 1 (EC:2.7.2.3) C00007366
5340 PLG plasminogen (EC:3.4.21.7) C00007366
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00007366
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00007366
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00007366
6401 SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 selectin E C00007366
4089 SMAD4, DPC4, JIP, MADH4, MYHRS SMAD family member 4 C00007366
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00007366
7015 TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT telomerase reverse transcriptase (EC:2.7.7.49) C00007366
8795 TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 tumor necrosis factor receptor superfamily, member 10b C00007366
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00007366
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00007366
7494 XBP1, TREB5, XBP-1, XBP2 X-box binding protein 1 C00007366

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (91)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103780 Alcohol dependence P08172
P14416
P31645
P47869
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#614490 Blood group, junior system; jr Q9UNQ0
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#609446 Generalized epilepsy and paroxysmal dyskinesia; gepd Q12791
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#605361 Spinocerebellar ataxia 14; sca14 P05129
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P24723
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#614916 Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 P62158
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (91)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00003 Acute myeloid leukemia (AML) P15144 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Q12791 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)

Diseases related to CTD interactions

70 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002318 Cardiovascular Diseases C00000919
C00007366
D008175 Lung Neoplasms C00000919
C00007366
D008113 Liver Neoplasms C00000919
C00007366
D056486 Drug-Induced Liver Injury C00000919
C00007366
D009422 Nervous System Diseases C00007366
D000435 Alcoholic Intoxication C00000919
D003930 Diabetic Retinopathy C00000919
D002545 Brain Ischemia C00000919
D006526 Hepatitis C C00000919
D015658 HIV Infections C00000919
D006986 Hypervitaminosis A C00000919
D008107 Liver Diseases C00000919
D053627 Asthenozoospermia C00000919
D008114 Liver Neoplasms, Experimental C00000919
D001145 Arrhythmias, Cardiac C00000919
D009369 Neoplasms C00000919
D009845 Oligospermia C00000919
D013272 Stomach Diseases C00000919
D013276 Stomach Ulcer C00000919
D015746 Abdominal Pain C00007366
D058186 Acute Kidney Injury C00007366
D000755 Anemia, Sickle Cell C00007366
D001247 Asthenia C00007366
C535393 Ataxia with vitamin E deficiency C00007366
D001284 Atrophy C00007366
D001836 Body Weight Changes C00007366
D001930 Brain Injuries C00007366
D002279 Carcinoma 256, Walker C00007366
D002471 Cell Transformation, Neoplastic C00007366
D002493 Central Nervous System Diseases C00007366
D003072 Cognition Disorders C00007366
D003556 Cystitis C00007366
D003924 Diabetes Mellitus, Type 2 C00007366
D064420 Drug-Related Side Effects and Adverse Reactions C00007366
D005334 Fever C00007366
D005355 Fibrosis C00007366
D005767 Gastrointestinal Diseases C00007366
D005923 Glomerulosclerosis, Focal Segmental C00007366
D006261 Headache C00007366
D006461 Hemolysis C00007366
D006949 Hyperlipidemias C00007366
D006965 Hyperplasia C00007366
D006973 Hypertension C00007366
D007511 Ischemia C00007366
D007674 Kidney Diseases C00007366
D008569 Memory Disorders C00007366
D009135 Muscular Diseases C00007366
D009203 Myocardial Infarction C00007366
D009325 Nausea C00007366
D009336 Necrosis C00007366
D009362 Neoplasm Metastasis C00007366
D009410 Nerve Degeneration C00007366
D006528 Carcinoma, Hepatocellular C00000919
D009436 Neural Tube Defects C00007366
D010014 Osteolysis C00007366
D010049 Ovarian Diseases C00007366
D010146 Pain C00007366
D011041 Poisoning C00007366
D011230 Precancerous Conditions C00007366
D011507 Proteinuria C00007366
D011561 Pseudoxanthoma Elasticum C00007366
D011657 Pulmonary Eosinophilia C00007366
D011832 Radiation Injuries C00007366
D051437 Renal Insufficiency C00007366
D015427 Reperfusion Injury C00007366
D012174 Retinitis Pigmentosa C00007366
D012640 Seizures C00007366
D014029 Tobacco Use Disorder C00007366
D014591 Uterine Diseases C00007366
D014717 Vertigo C00007366