PCIDB

KNApSAcK Metabolite C00010883

Metabolite

KNApSAcK Entry

id C00010883
Name Carveol / p-Mentha-1,8-dien-6-ol
CAS RN 99-48-9
Standard InChI InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3
Standard InChI (Main Layer) InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3

Cluster

Phytochemical cluster No. 35
KCF-S cluster No. 1555

Link

ChEMBL

By standard InChI CHEMBL1385229
By standard InChI Main Layer CHEMBL1385229 CHEMBL1907992 CHEMBL1908058

KEGG

By LinkDB C11409

CTD

By CAS RN C075856

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P22310 UDP-glucuronosyltransferase 1-4 Enzyme CHEMBL1907992 CHEMBL1908082 (1)
3 / 0
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL1385229 CHEMBL1613995 (1)
7 / 44
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL1385229 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
O60656 UDP-glucuronosyltransferase 1-9 Enzyme CHEMBL1907992 CHEMBL1908086 (1)
0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein CHEMBL1385229 CHEMBL1963893 (1)
0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme CHEMBL1908058 CHEMBL1908080 (1)
5 / 1

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C075856 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B carveol results in increased expression of RHOB protein increases expression
protein 12671036
C075856 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B Mevalonic Acid affects the reaction [carveol results in increased expression of RHOB protein] affects reaction
/ increases expression
protein 12671036

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#133239 Esophageal cancer P04637
#143500 Gilbert syndrome P22309
P22310
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#260500 Papilloma of choroid plexus; cpp P04637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637

KEGG DISEASE (40)

KEGG disease name UniProt
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)