Citrus reticulata

• Index
• Plant Species
• Natural Activity
• Metabolite list (71)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Citrus reticulata
Genus	Citrus
Family	Rutaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Citrus reticulata
Linked NCBI taxonomy ID	85571
Linked level	species

Family

Family in NCBI taxonomy	Rutaceae
ID	23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Natural Activity

List (24)

Species	Activity
Citrus reticulata Blanco	Antibacterial
Citrus reticulata Blanco	Anticancer
Citrus reticulata Blanco	Antiemetic
Citrus reticulata Blanco	Antimetastatic
Citrus reticulata Blanco	Antiseptic
Citrus reticulata Blanco	Antispasmodic
Citrus reticulata Blanco	Antiviral
Citrus reticulata Blanco	Aphrodisiac
Citrus reticulata Blanco	Aromatic
Citrus reticulata Blanco	Astringent
Citrus reticulata Blanco	Candidicide
Citrus reticulata Blanco	Decongestant
Citrus reticulata Blanco	Digestive
Citrus reticulata Blanco	Expectorant
Citrus reticulata Blanco	Fungicide
Citrus reticulata Blanco	Gastrogogue
Citrus reticulata Blanco	Laxative
Citrus reticulata Blanco	Mucolytic
Citrus reticulata Blanco	Myorelaxant
Citrus reticulata Blanco	Secretagogue
Citrus reticulata Blanco	Sedative
Citrus reticulata Blanco	Stimulant
Citrus reticulata Blanco	Thermogenic
Citrus reticulata Blanco	Tonic

Metabolite list (71)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003928	Sudachitin / Menthocubanone / Menthokubanone / 4',5,7-Trihydroxy-3',6,8-trimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one	CHEMBL479233				No. 3	No. 15
C00004544	3-O-Methylalnusin / Alnusin 3-methyl ether / 5,7-Dihydroxy-3,6-dimethoxyflavone / 5,7-Dihydroxy-3,6-dimethoxy-2-phenyl-4H-1-benzopyran-4-one					No. 3	No. 15
C00003845	Eupatilin / 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one	CHEMBL312750	C045325	15 / 7 / 2		No. 3	No. 15
C00003852	Isoscutellarein 7,8-dimethyl ether					No. 3	No. 15
C00003898	5-Hydroxy-6,7,3',4'-tetramethoxyflavone / 6-Hydroxyluteolin 6,7,3',4'-tetramethyl ether / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one	CHEMBL226508	C045324			No. 8	No. 15
C00003871	5,7,3',4'-Tetramethoxyflavone / Luteolin 5,7,3',4'-tetramethyl ether	CHEMBL327340	C103111		1 / 0	No. 8	No. 15
C00003897	6-Hydroxyluteolin 5,6,3',4'-tetramethyl ether					No. 8	No. 15
C00003935	3'-Hydroxy-5,6,7,8,4'-pentamethoxyflavone	CHEMBL225704				No. 8	No. 15
C00003912	Isosinensetin / 6-Demethoxynobiletin / 5,7,8,3',4'-Pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5,7,8-trimethoxy-4H-1-benzopyran-4-one	CHEMBL451707				No. 8	No. 15
C00013315	4'-Hydroxy-5,6,7,8-tetramethoxyflavone / 2-(4-Hydroxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one	CHEMBL479077				No. 8	No. 15
C00004804	3,3',4',5,6,7,8-Heptamethoxyflavone / 3,5,6,7,8,3',4'-Heptamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-3,5,6,7,8-pentamethoxy-4H-1-benzopyran-4-one	CHEMBL77993	C059294	17 / 10 / 2		No. 8	No. 15
C00003936	Demethylnobiletin / 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one	CHEMBL75978		21 / 22 / 16		No. 8	No. 15
C00005079	4'-Hydroxy-3,6-dimethoxy-6'',6''-dimethylpyrano[2,3:7,8]flavone					No. 24	No. 15
C00000931	Zeaxanthin / all-trans-Zeaxanthin	CHEMBL1357855 CHEMBL2359248	C005881	4 / 2 / 3	1 / 0	No. 26	No. 59
C00003854	5-Hydroxy-7,8,4'-trimethoxyflavone / 5-Hydroxy-4',7,8-trimethoxyflavone / Isoscutellarein 7,8,4'-trimethyl ether / 5-Hydroxy-7,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one					No. 35	No. 15
C00003821	5,7,4'-Trimethoxyflavone / Apigenin 5,7,4'-trimethyl ether	CHEMBL1087720	C103112	1 / 1 / 0	1 / 0	No. 35	No. 15
C00000001	GA1 / Gibberellin A1		C422660			No. 40	No. 41
C00000008	GA8 / Gibberellin A8					No. 40	No. 41
C00000044	GA44 / Gibberellin A44					No. 40	No. 41
C00000029	GA29 / Gibberellin A29					No. 40	No. 41
C00000004	GA4 / Gibberellin A4					No. 40	No. 41
C00000020	GA20 / Gibberellin A20					No. 40	No. 41
C00003785	Rubixanthin					No. 131	No. 59
C00000019	GA19 / Gibberellin A19		C120175			No. 187	No. 41
C00000017	GA17 / Gibberellin A17					No. 187	No. 41
C00000053	GA53 / Gibberellin A53					No. 187	No. 41
C00003131	beta-Farnesene / (E)-beta-Farnesene / beta-trans-Farnesene		C062671			No. 404	No. 38
C00048367	Curcumene	CHEMBL469717	C086829			No. 456	No. 38
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00003110	Caryophyllene / (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene	CHEMBL445740 CHEMBL448700		2 / 3 / 7		No. 478	No. 38
C00001265	Pentadecane	CHEMBL1234557	C033245	2 / 8 / 37		No. 599
C00030472	Heptadecane		C016486			No. 599
C00048301	8-Heptadecene					No. 599
C00007242	beta-Bisabolene / l-beta-Bisabolene / (-)-beta-Bisabolene	CHEMBL444389 CHEMBL1077088 CHEMBL2001434				No. 701	No. 38
C00003166	Nerolidol	CHEMBL25424 CHEMBL508801 CHEMBL561014 CHEMBL1923157		3 / 3 / 1		No. 726	No. 38
C00020074	Calamenene / (-)-cis-Calamenene					No. 824
C00000823	Limonene	CHEMBL15799 CHEMBL449062	C008281	7 / 21 / 48	6 / 6	No. 848	No. 35
C00003050	Perilla aldehyde / (R)-(+)-Perillaldehyde	CHEMBL442913 CHEMBL469537	C033342	2 / 1 / 0	9 / 0	No. 848	No. 35
C00007535	Phenylacetaldehyde / Benzeneacetaldehyde / Phenylacetic aldehyde		C013192		3 / 0	No. 885
C00048326	Benzene acetonitrile					No. 885
C00002663	2-Phenylethanol / Phenethyl alcohol / Phenylethyl alcohol / beta-Phenethyl alcohol	CHEMBL448500	D010626	2 / 1 / 1		No. 885
C00003047	Linalool / (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol	CHEMBL25306 CHEMBL235672	C018584	6 / 8 / 2	35 / 4	No. 958	No. 34
C00000155	Thymol	CHEMBL29411	D013943	9 / 17 / 14	12 / 0	No. 969	No. 35
C00000184	alpha-Thujene					No. 1343	No. 35
C00031258	Sabinene / 4(10)-Thujene	CHEMBL452687	C035127			No. 1343	No. 35
C00007453	Cyclohexane / beta-Elemene	CHEMBL448502 CHEMBL479707				No. 1400
C00010883	Carveol / p-Mentha-1,8-dien-6-ol	CHEMBL1385229 CHEMBL1907992 CHEMBL1908058	C075856	6 / 15 / 40	1 / 0	No. 1555	No. 35
C00003035	Geranial / (E)-alpha-Citral	CHEMBL1080997		6 / 7 / 9		No. 1575	No. 34
C00000855	Nerol / cis-Geraniol	CHEMBL25719 CHEMBL452683		96 / 41 / 41		No. 1575	No. 34
C00048486	Neo-allo-ocimene					No. 1698	No. 34
C00048310	Allo-Ocimene		C015659			No. 1698	No. 34
C00030767	Methyl salicylate	CHEMBL108545	C033069	92 / 52 / 46	29 / 3	No. 2169
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00000853	Myrcene	CHEMBL455491	C008574	3 / 3 / 3		No. 2285	No. 34
C00048315	alpha-Myrcene					No. 2285	No. 34
C00003060	alpha-Terpinene					No. 2468	No. 35
C00029353	(Z)-Jasmone / cis-Jasmone		C086299			No. 3251
C00001418	Indole	CHEMBL15844	C030374	13 / 5 / 6	6 / 0	No. 3673
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00034600	Methyl anthranilate	CHEMBL1493986	C038892	3 / 3 / 3		No. 4170
C00048248	(Z)-Ocimene / cis-Ocimene					No. 4949
C00048263	2,6-Dimethyl-1,3,5,7-octatetraene					No. 4953
C00034775	6-Methyl-5-hepten-2-one	CHEMBL46340	C029750			No. 5297
C00048304	Acetone	CHEMBL14253	D000096	1 / 11 / 10	10 / 8	No. 5308
C00000136	1,8-Cineole	CHEMBL485259 CHEMBL1397305		99 / 57 / 50		No. 5413	No. 35
C00034989	(E)-Ocimene / trans-Ocimene					No. 6181
C00034452	Benzaldehyde	CHEMBL15972	C032175	8 / 7 / 3	3 / 1	No. 6311
C00048350	Carvyl acetate	CHEMBL1351619		4 / 3 / 2		No. 6846
C00048498	n-Phenylformamide	CHEMBL1232659	C045976	6 / 2 / 0		No. 8296
C00019560	Ethanol	CHEMBL545	D000431	92 / 39 / 33	199 / 193	No. 8862

Human Protein / Gene in interactions

160 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P16473	Thyrotropin receptor	Glycohormone receptor	C00000136 C00000805 C00000853 C00010883 C00019560 C00030767 C00048350	3 / 2
P02545	Prelamin-A/C	Unclassified protein	C00000136 C00000155 C00000823 C00003936 C00030767 C00048304	11 / 10
P03372	Estrogen receptor	NR3A1	C00000136 C00000855 C00001265 C00019560 C00030767 C00034452	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00000136 C00000805 C00000855 C00003936 C00019560 C00030767	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00003035 C00003936 C00019560 C00034452 C00034600 C00048498	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000136 C00000155 C00000823 C00000855 C00019560 C00030767	0 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000136 C00000855 C00003936 C00019560 C00030767	0 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000136 C00000855 C00001418 C00019560 C00030767	1 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000136 C00000855 C00019560 C00030767 C00034452	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000136 C00000853 C00000855 C00019560 C00030767	0 / 1
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000136 C00000855 C00019560 C00030767	1 / 0
P29466	Caspase-1	C14	C00000136 C00000855 C00019560 C00030767	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000136 C00000855 C00019560 C00030767	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000136 C00000855 C00019560 C00030767	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000823 C00000855 C00034452 C00048498	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000136 C00000855 C00019560 C00030767	2 / 2
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000136 C00000855 C00019560 C00030767	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000823 C00003035 C00003047 C00003166	3 / 1
P30542	Adenosine receptor A1	Adenosine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P08246	Neutrophil elastase	S1A	C00000136 C00000855 C00019560 C00030767	2 / 1
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000136 C00000855 C00019560 C00030767	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000136 C00000855 C00019560 C00030767	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000136 C00000855 C00019560 C00030767	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000136 C00000855 C00019560 C00030767	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000136 C00000855 C00019560 C00030767	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000136 C00000855 C00019560 C00030767	0 / 1
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000136 C00000855 C00019560 C00030767	1 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000823 C00034600 C00048350 C00048498	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000136 C00000855 C00019560 C00030767	1 / 8
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000136 C00000855 C00019560 C00030767	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000136 C00000855 C00019560 C00030767	2 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000136 C00000855 C00019560 C00030767	2 / 1
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000136 C00000855 C00019560 C00030767	2 / 2
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000136 C00000855 C00019560 C00030767	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000136 C00000855 C00019560 C00030767	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000136 C00000855 C00019560 C00030767	1 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000136 C00000855 C00019560 C00030767	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000136 C00000855 C00019560 C00030767	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000855 C00003047 C00003166 C00048350	0 / 0
O75496	Geminin	Unclassified protein	C00000136 C00000931 C00002663 C00048498	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000136 C00000855 C00019560 C00030767	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000136 C00000855 C00019560 C00030767	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000136 C00000855 C00019560 C00030767	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000136 C00000855 C00019560 C00030767	1 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P08311	Cathepsin G	S1A	C00000136 C00000855 C00019560 C00030767	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P03956	Interstitial collagenase	M10A	C00000136 C00000855 C00019560 C00030767	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000136 C00000855 C00019560 C00030767	1 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000136 C00000855 C00019560 C00030767	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000136 C00000855 C00019560 C00030767	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000136 C00000855 C00019560 C00030767	1 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000136 C00000855 C00019560 C00030767	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000136 C00000855 C00019560 C00030767	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000136 C00000855 C00019560 C00030767	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000136 C00000855 C00019560 C00030767	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000136 C00000855 C00019560 C00030767	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000136 C00000855 C00019560 C00030767	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000136 C00000855 C00019560 C00030767	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000136 C00000855 C00019560 C00030767	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000136 C00000855 C00019560 C00030767	1 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000136 C00000855 C00019560 C00030767	0 / 0
Q9BVA1	Tubulin beta-2B chain	Structural	C00003845 C00003936 C00004804	1 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	C00003845 C00003936 C00004804	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	C00003845 C00003936 C00004804	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	C00003845 C00003936 C00004804	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00000823 C00001265 C00010883	7 / 37
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00019560 C00048350	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00000155 C00000855 C00003047	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000155 C00003047 C00010883	3 / 0
Q13885	Tubulin beta-2A chain	Structural	C00003845 C00003936 C00004804	0 / 0
P68363	Tubulin alpha-1B chain	Unclassified protein	C00003845 C00003936 C00004804	0 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	C00003845 C00003936 C00004804	0 / 0
Q13509	Tubulin beta-3 chain	Structural	C00003845 C00003936 C00004804	2 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00000136 C00003047 C00048498	0 / 0
P68366	Tubulin alpha-4A chain	Structural	C00003845 C00003936 C00004804	0 / 0
P68371	Tubulin beta-4B chain	Structural	C00003845 C00003936 C00004804	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	C00003845 C00003936 C00004804	1 / 1
P11473	Vitamin D3 receptor	NR1I1	C00000855 C00000931 C00030767	2 / 3
Q9H4B7	Tubulin beta-1 chain	Structural	C00003845 C00003936 C00004804	1 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000155 C00003047 C00010883	5 / 1
Q3ZCM7	Tubulin beta-8 chain	Structural	C00003845 C00003936 C00004804	0 / 0
P04350	Tubulin beta-4A chain	Structural	C00003845 C00003936 C00004804	2 / 0
P07437	Tubulin beta chain	Structural	C00003845 C00003936 C00004804	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00034452 C00048498	2 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000136 C00003936	4 / 3
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000155 C00010883	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00003035 C00003050	0 / 0
P10275	Androgen receptor	NR3C4	C00000136 C00003035	3 / 4
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000931 C00003166	0 / 0
P08183	Multidrug resistance protein 1	drug	C00003821 C00004804	1 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000855 C00003110	1 / 2
O00255	Menin	Unclassified protein	C00000855 C00003110	2 / 5
Q96RI1	Bile acid receptor	NR1H4	C00000853 C00000855	0 / 0
O75762	Transient receptor potential cation channel subfamily A member 1	Unclassified protein	C00000155 C00003050	1 / 0
Q7Z2W7	Transient receptor potential cation channel subfamily M member 8	Unclassified protein	C00000136	0 / 0
P23141	Liver carboxylesterase 1	Enzyme	C00001418	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00001418	1 / 1
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000136	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000931	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002663	1 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003936	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00000823	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00003035	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00003035	1 / 4
P05107	Integrin beta-2	Membrane receptor	C00001418	1 / 1
P05362	Intercellular adhesion molecule 1	Adhesion	C00001418	1 / 2
P20701	Integrin alpha-L	Membrane receptor	C00001418	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00001418	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00001418	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000155	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00001418	0 / 0
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00034452	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000155	0 / 0
P10145	Interleukin-8	Secreted protein	C00034452	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00001418	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00010883	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00001418	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00001418	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00034452	4 / 2
P55263	Adenosine kinase	Enzyme	C00001418	1 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004804	2 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00034600	3 / 3
P55055	Oxysterols receptor LXR-beta	NR1H3	C00000136	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00000136	0 / 0

278 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00007535 C00019560 C00030767 C00048304
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000823 C00019560 C00030767
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00003050 C00007535 C00019560
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003047 C00019560 C00030767
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861 C00003047 C00019560
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000155 C00000823 C00019560
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00003047 C00019560 C00030767
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00003047 C00007535
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000823 C00003047
4852	NPY, PYY4	neuropeptide Y	C00000823 C00003047
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000155 C00019560
581	BAX, BCL2L4	BCL2-associated X protein	C00000155 C00019560
3678	ITGA5, CD49e, FNRA, VLA5A	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	C00019560 C00048304
2263	FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25	fibroblast growth factor receptor 2 (EC:2.7.10.1)	C00019560 C00048304
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00019560 C00048304
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000823 C00003047
847	CAT	catalase (EC:1.11.1.6)	C00019560 C00048304
388	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6	ras homolog family member B	C00003050 C00010883
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00003050 C00019560
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000155 C00030767
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000155 C00030767
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003047 C00019560
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003047 C00019560
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000155 C00030767
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000155 C00019560
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003047 C00019560
2512	FTL, NBIA3	ferritin, light polypeptide	C00019560 C00030767
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00019560 C00030767
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00019560 C00034452
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00003047 C00003050
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00019560 C00048304
5884	RAD17, CCYC, HRAD17, R24L, RAD17SP, RAD24	RAD17 homolog (S. pombe)	C00019560
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003047
8850	KAT2B, CAF, P, P/CAF, PCAF	K(lysine) acetyltransferase 2B (EC:2.3.1.48)	C00003047
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00003047
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00003047
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00003047
100124292			C00003047
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00003047
7471	WNT1, BMND16, INT1, OI15	wingless-type MMTV integration site family, member 1	C00003047
26118	WSB1, SWIP1, WSB-1	WD repeat and SOCS box containing 1	C00003047
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00001418
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00001418
4157	MC1R, CMM5, MSH-R, SHEP2	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	C00001418
4159	MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL	melanocortin 3 receptor	C00001418
4160	MC4R	melanocortin 4 receptor	C00001418
4161	MC5R, MC2	melanocortin 5 receptor	C00001418
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00003047
218	ALDH3A1, ALDH3, ALDHIII	aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)	C00034452
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00034452
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00030767
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00030767
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00030767
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00030767
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00030767
2010	EMD, EDMD, LEMD5, STA	emerin	C00030767
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00003047
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00030767
3297	HSF1, HSTF1	heat shock transcription factor 1	C00003047
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00030767
9514	GAL3ST1, CST	galactose-3-O-sulfotransferase 1 (EC:2.8.2.11)	C00030767
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00030767
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00030767
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00030767
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00030767
4883	NPR3, ANP-C, ANPR-C, ANPRC, C5orf23, GUCY2B, NPR-C, NPRC	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	C00030767
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00030767
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00030767
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00030767
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00030767
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00030767
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003047
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00030767
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00003047
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00003047
1555	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450	cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1)	C00003050
9817	KEAP1, INrf2, KLHL19	kelch-like ECH-associated protein 1	C00003050
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00003050
1447	CSN2, CASB	casein beta	C00003047
5906	RAP1A, KREV-1, KREV1, RAP1, SMGP21	RAP1A, member of RAS oncogene family	C00003050
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00003050
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003047
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00003871
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00003821
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003047
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003047
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00048304
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003047
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003047
3596	IL13, IL-13, P600	interleukin 13	C00048304
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00048304
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00048304
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003047
23536	ADAT1, HADAT1	adenosine deaminase, tRNA-specific 1 (EC:3.5.4.34)	C00019560
124	ADH1A, ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1)	C00019560
125	ADH1B, ADH2	alcohol dehydrogenase 1B (class I), beta polypeptide (EC:1.1.1.1)	C00019560
126	ADH1C, ADH3	alcohol dehydrogenase 1C (class I), gamma polypeptide (EC:1.1.1.1)	C00019560
127	ADH4, ADH-2	alcohol dehydrogenase 4 (class II), pi polypeptide (EC:1.1.1.1)	C00019560
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00019560
131	ADH7, ADH4	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (EC:1.1.1.1)	C00019560
22977	AKR7A3, AFAR2	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	C00019560
273	AMPH, AMPH1	amphiphysin	C00019560
162	AP1B1, ADTB1, AP105A, BAM22, CLAPB2	adaptor-related protein complex 1, beta 1 subunit	C00019560
79065	ATG9A, APG9L1, MGD3208, mATG9	autophagy related 9A	C00019560
506	ATP5B, ATPMB, ATPSB	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14)	C00019560
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00003047
8678	BECN1, ATG6, VPS30, beclin1	beclin 1, autophagy related	C00019560
274	BIN1, AMPH2, AMPHL, SH3P9	bridging integrator 1	C00019560
708	C1QBP, GC1QBP, HABP1, SF2p32, gC1Q-R, gC1qR, p32	complement component 1, q subcomponent binding protein	C00019560
832	CAPZB, CAPB, CAPPB, CAPZ	capping protein (actin filament) muscle Z-line, beta	C00019560
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00000823
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000931
857	CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV	caveolin 1, caveolae protein, 22kDa	C00019560
83446	CCDC70	coiled-coil domain containing 70	C00019560
54535	CCHCR1, C6orf18, HCR, SBP	coiled-coil alpha-helical rod protein 1	C00019560
894	CCND2, KIAK0002	cyclin D2	C00019560
994	CDC25B	cell division cycle 25B (EC:3.1.3.48)	C00019560
55664	CDC37L1, CDC37B, HARC	cell division cycle 37-like 1	C00019560
1003	CDH5, 7B4, CD144	cadherin 5, type 2 (vascular endothelium)	C00019560
23552	CDK20, CCRK, CDCH, P42, PNQALRE	cyclin-dependent kinase 20 (EC:2.7.11.22)	C00019560
1050	CEBPA, C/EBP-alpha, CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	C00019560
55165	CEP55, C10orf3, CT111, URCC6	centrosomal protein 55kDa	C00019560
1066	CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1	carboxylesterase 1 (EC:3.1.1.1 3.1.1.56)	C00019560
1138	CHRNA5, LNCR2	cholinergic receptor, nicotinic, alpha 5 (neuronal)	C00019560
1140	CHRNB1, ACHRB, CHRNB, CMS1D, CMS2A, SCCMS	cholinergic receptor, nicotinic, beta 1 (muscle)	C00019560
1191	CLU, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2	clusterin	C00019560
1266	CNN3	calponin 3, acidic	C00019560
1278	COL1A2, OI4	collagen, type I, alpha 2	C00019560
1417	CRYBB3, CATCN2, CRYB3, CTRCT22	crystallin, beta B3	C00019560
1442	CSH1, CS-1, CSA, CSMT, PL, hCS-A	chorionic somatomammotropin hormone 1 (placental lactogen)	C00019560
1535	CYBA, p22-PHOX	cytochrome b-245, alpha polypeptide	C00019560
1536	CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX	cytochrome b-245, beta polypeptide	C00019560
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00019560
10591	DNPH1, C6orf108, RCL, RP3-330M21.3, dJ330M21.3	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	C00019560
1837	DTNA, D18S892E, DRP3, DTN, DTN-A, LVNC1	dystrobrevin, alpha	C00019560
338599	DUPD1, DUSP27, FMDSP	dual specificity phosphatase and pro isomerase domain containing 1 (EC:3.1.3.16 3.1.3.48)	C00019560
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00019560
10961	ERP29, C12orf8, ERp28, ERp31, PDI-DB, PDIA9	endoplasmic reticulum protein 29	C00019560
2177	FANCD2, FA-D2, FA4, FACD, FAD, FAD2, FANCD	Fanconi anemia, complementation group D2	C00019560
84261	FBXW9, Fbw9	F-box and WD repeat domain containing 9	C00019560
2348	FOLR1, FBP, FOLR	folate receptor 1 (adult)	C00019560
2526	FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, LeX, SSEA-1	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (EC:2.4.1.-)	C00019560
2534	FYN, SLK, SYN, p59-FYN	FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2)	C00019560
2670	GFAP	glial fibrillary acidic protein	C00019560
2688	GH1, GH, GH-N, GHN, IGHD1B, hGH-N	growth hormone 1	C00019560
51031	GLOD4, C17orf25, HC71	glyoxalase domain containing 4	C00019560
2741	GLRA1, HKPX1, STHE	glycine receptor, alpha 1	C00019560
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00019560
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00019560
2952	GSTT1	glutathione S-transferase theta 1 (EC:2.5.1.18)	C00019560
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00019560
1839	HBEGF, DTR, DTS, DTSF, HEGFL	heparin-binding EGF-like growth factor	C00019560
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00019560
3181	HNRNPA2B1, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1	heterogeneous nuclear ribonucleoprotein A2/B1	C00019560
3190	HNRNPK, CSBP, HNRPK, TUNP	heterogeneous nuclear ribonucleoprotein K	C00019560
3359	HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	C00019560
9177	HTR3B, 5-HT3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	C00019560
27429	HTRA2, OMI, PARK13, PRSS25	HtrA serine peptidase 2 (EC:3.4.21.108)	C00019560
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00019560
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00019560
3486	IGFBP3, BP-53, IBP3	insulin-like growth factor binding protein 3	C00019560
3589	IL11, AGIF, IL-11	interleukin 11	C00019560
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00019560
3708	ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29	inositol 1,4,5-trisphosphate receptor, type 1	C00019560
83999	KREMEN1, KREMEN, KRM1	kringle containing transmembrane protein 1	C00019560
3875	KRT18, CYK18, K18	keratin 18	C00019560
3856	KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO	keratin 8	C00019560
3897	L1CAM, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1	L1 cell adhesion molecule	C00019560
4017	LOXL2, LOR2, WS9-14	lysyl oxidase-like 2 (EC:1.4.3.-)	C00019560
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00019560
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00019560
4144	MAT2A, MATA2, MATII, SAMS2	methionine adenosyltransferase II, alpha (EC:2.5.1.6)	C00019560
4148	MATN3, DIPOA, EDM5, HOA, OADIP, OS2	matrilin 3	C00019560
406931	MIR139, MIR139-3p, MIRN139	microRNA 139	C00019560
406987	MIR204, MIRN204, miRNA204	microRNA 204	C00019560
100126336	MIR208B, MIRN208B	microRNA 208b	C00019560
407018	MIR27A, MIR27, MIRN27A	microRNA 27a	C00019560
442894	MIR302B, MIRN302B	microRNA 302b	C00019560
693120	MIR33B, MIRN33B, hsa-mir-33b	microRNA 33b	C00019560
407040	MIR34A, MIRN34A, miRNA34A, mir-34	microRNA 34a	C00019560
442914	MIR369, MIR369-3, MIRN369, MIRN369-3, hsa-mir-369	microRNA 369	C00019560
442915	MIR370, MIRN370, hsa-mir-370	microRNA 370	C00019560
442918	MIR373, MIRN373, hsa-mir-373, miRNA373	microRNA 373	C00019560
494324	MIR375, MIRN375, hsa-mir-375, miRNA375	microRNA 375	C00019560
574451	MIR432, MIRN432, hsa-mir-432	microRNA 432	C00019560
619552	MIR483, MIRN483, hsa-mir-483	microRNA 483	C00019560
574450	MIR493, MIRN493, hsa-mir-493	microRNA 493	C00019560
574456	MIR497, MIRN497, hsa-mir-497	microRNA 497	C00019560
574472	MIR518F, MIRN518F	microRNA 518f	C00019560
574471	MIR523, MIRN523, hsa-mir-523	microRNA 523	C00019560
693191	MIR606, MIRN606, hsa-mir-606	microRNA 606	C00019560
724026	MIR656, MIRN656, hsa-mir-656	microRNA 656	C00019560
100126326	MIR936, MIRN936, hsa-mir-936	microRNA 936	C00019560
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00019560
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00019560
4595	MUTYH, CYP2C, MYH	mutY homolog (EC:3.2.2.-)	C00019560
4638	MYLK, AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK	myosin light chain kinase (EC:2.7.11.18)	C00019560
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00019560
4688	NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX	neutrophil cytosolic factor 2	C00019560
4791	NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	C00019560
4830	NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1	NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6)	C00019560
8996	NOL3, ARC, FCM, MYP, NOP, NOP30	nucleolar protein 3 (apoptosis repressor with CARD domain)	C00019560
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00019560
4854	NOTCH3, CADASIL, CASIL, IMF2	notch 3	C00019560
27035	NOX1, GP91-2, MOX1, NOH-1, NOH1	NADPH oxidase 1	C00019560
4897	NRCAM	neuronal cell adhesion molecule	C00019560
8829	NRP1, BDCA4, CD304, NP1, NRP, VEGF165R	neuropilin 1	C00019560
100506658	OCLN, BLCPMG	occludin (EC:2.1.1.67)	C00019560
4968	OGG1, HMMH, HOGG1, MUTM, OGH1	8-oxoguanine DNA glycosylase (EC:4.2.99.18)	C00019560
4986	OPRK1, K-OR-1, KOR, KOR-1, OPRK	opioid receptor, kappa 1	C00019560
4988	OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM	opioid receptor, mu 1	C00019560
84876	ORAI1, CRACM1, IMD9, ORAT1, TMEM142A	ORAI calcium release-activated calcium modulator 1	C00019560
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00019560
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00019560
5173	PDYN, ADCA, PENKB, SCA23	prodynorphin	C00019560
5179	PENK	proenkephalin	C00019560
5204	PFDN5, MM-1, MM1, PFD5	prefoldin subunit 5	C00019560
25796	PGLS, 6PGL	6-phosphogluconolactonase (EC:3.1.1.31)	C00019560
5245	PHB, PHB1	prohibitin	C00019560
26227	PHGDH, 3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA	phosphoglycerate dehydrogenase (EC:1.1.1.95)	C00019560
5335	PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1	phospholipase C, gamma 1 (EC:3.1.4.11)	C00019560
5352	PLOD2, LH2, TLH	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (EC:1.14.11.4)	C00019560
57048	PLSCR3	phospholipid scramblase 3	C00019560
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00019560
5395	PMS2, HNPCC4, PMS2CL, PMSL2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	C00019560
5426	POLE, CRCS12, FILS, POLE1	polymerase (DNA directed), epsilon, catalytic subunit (EC:2.7.7.7)	C00019560
5443	POMC, ACTH, CLIP, LPH, MSH, NPP, POC	proopiomelanocortin	C00019560
5451	POU2F1, OCT1, OTF1, oct-1B	POU class 2 homeobox 1	C00019560
5460	POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4	POU class 5 homeobox 1	C00019560
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00019560
100136658			C00019560
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00019560
8497	PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	C00019560
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00019560
9588	PRDX6, 1-Cys, AOP2, NSGPx, PRX, aiPLA2, p29	peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15)	C00019560
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00019560
5579	PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2	protein kinase C, beta (EC:2.7.11.13)	C00019560
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00019560
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00019560
2185	PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK	protein tyrosine kinase 2 beta (EC:2.7.10.2)	C00019560
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00019560
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00003047
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00019560
6236	RRAD, RAD, RAD1, REM3	Ras-related associated with diabetes	C00019560
6275	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98	S100 calcium binding protein A4	C00019560
6342	SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX	sterol carrier protein 2 (EC:2.3.1.176)	C00019560
23513	SCRIB, CRIB1, SCRB1, SCRIB1, Vartul	scribbled planar cell polarity protein	C00019560
6573	SLC19A1, CHMD, FOLT, IFC1, REFC, RFC1	solute carrier family 19 (folate transporter), member 1	C00019560
2030	SLC29A1, ENT1	solute carrier family 29 (equilibrative nucleoside transporter), member 1	C00019560
60682	SMAP1, SMAP-1	small ArfGAP 1	C00019560
6678	SPARC, ON	secreted protein, acidic, cysteine-rich (osteonectin)	C00019560
6696	SPP1, BNSP, BSPI, ETA-1, OPN	secreted phosphoprotein 1	C00019560
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00019560
6723	SRM, PAPT, SPDSY, SPS1, SRML1	spermidine synthase (EC:2.5.1.16)	C00019560
56910	STARD7, GTT1	StAR-related lipid transfer (START) domain containing 7	C00019560
6786	STIM1, D11S4896E, GOK, IMD10, TAM	stromal interaction molecule 1	C00019560
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00019560
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00019560
6783	SULT1E1, EST, EST-1, ST1E1, STE	sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4)	C00019560
6822	SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14)	C00019560
9095	TBX19, TBS19, TPIT, dJ747L4.1	T-box 19	C00019560
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00019560
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00019560
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00019560
7082	TJP1, ZO-1	tight junction protein 1	C00019560
7083	TK1, TK2	thymidine kinase 1, soluble (EC:2.7.1.21)	C00019560
7167	TPI1, TIM, TPI, TPID	triosephosphate isomerase 1 (EC:5.3.1.1)	C00019560
10107	TRIM10, HERF1, RFB30, RNF9	tripartite motif containing 10	C00019560
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00019560
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00019560
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00019560
7515	XRCC1, RCC	X-ray repair complementing defective repair in Chinese hamster cells 1	C00019560
25925	ZNF521, EHZF, Evi3	zinc finger protein 521	C00019560
9131	AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	C00000155
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000155
162514	TRPV3, OLMS, VRL3	transient receptor potential cation channel, subfamily V, member 3	C00000155
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000155
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000155

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