PCIDB

KNApSAcK Metabolite C00004804

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00004804
Name	3,3',4',5,6,7,8-Heptamethoxyflavone / 3,5,6,7,8,3',4'-Heptamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-3,5,6,7,8-pentamethoxy-4H-1-benzopyran-4-one
CAS RN	1178-24-1
Standard InChI	InChI=1S/C22H24O9/c1-24-12-9-8-11(10-13(12)25-2)16-19(27-4)15(23)14-17(26-3)20(28-5)22(30-7)21(29-6)18(14)31-16/h8-10H,1-7H3
Standard InChI (Main Layer)	InChI=1S/C22H24O9/c1-24-12-9-8-11(10-13(12)25-2)16-19(27-4)15(23)14-17(26-3)20(28-5)22(30-7)21(29-6)18(14)31-16/h8-10H,1-7H3

Cluster

Phytochemical cluster	No. 15
KCF-S cluster	No. 8

Link

ChEMBL

By standard InChI	CHEMBL77993
By standard InChI Main Layer	CHEMBL77993

KEGG

By LinkDB

CTD

By CAS RN	C059294

Species

Summary

Plant class

class name	count
rosids	5
Magnoliophyta	1

Family

family name	count
Rutaceae	5
Lauraceae	1

List (6)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Citrus hassaku	488171	Rutaceae	rosids	Viridiplantae
Citrus madurensis	164113	Rutaceae	rosids	Viridiplantae
Citrus paradisi	37656	Rutaceae	rosids	Viridiplantae
Citrus reticulata	85571	Rutaceae	rosids	Viridiplantae
Citrus sinensis	2711	Rutaceae	rosids	Viridiplantae
Laurus nobilis L.	85222	Lauraceae	Magnoliophyta	Viridiplantae

Human Protein / Gene in interaction

17 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
P08183	Multidrug resistance protein 1	drug	CHEMBL77993	CHEMBL1687396 (1) CHEMBL2077301 (1)	1 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	CHEMBL77993	CHEMBL1687393 (1) CHEMBL1687394 (1)	2 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
P68366	Tubulin alpha-4A chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	1 / 0
P04350	Tubulin beta-4A chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	2 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
P07437	Tubulin beta chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	1 / 1
P68371	Tubulin beta-4B chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q13509	Tubulin beta-3 chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	2 / 1
P68363	Tubulin alpha-1B chain	Unclassified protein	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q13885	Tubulin beta-2A chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9BVA1	Tubulin beta-2B chain	Structural	CHEMBL77993	CHEMBL818984 (1) CHEMBL820476 (1)	1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM	preferred title	UniProt
#614490	Blood group, junior system; jr	Q9UNQ0
#614039	Cortical dysplasia, complex, with other brain malformations 1; cdcbm1	Q13509
#128101	Dystonia 4, torsion, autosomal dominant; dyt4	P04350
#600638	Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a	Q13509
#612244	Inflammatory bowel disease 13; ibd13	P08183
#612438	Leukodystrophy, hypomyelinating, 6; hld6	P04350
#611603	Lissencephaly 3; lis3	Q71U36
#613112	Macrothrombocytopenia, autosomal dominant, tubb1-related	Q9H4B7
#610031	Polymicrogyria, symmetric or asymmetric; pmgysa	Q9BVA1
#138900	Uric acid concentration, serum, quantitative trait locus 1; uaqtl1	Q9UNQ0

KEGG DISEASE (2)

KEGG	disease name	UniProt
H00838	Congenital fibrosis of the extraocular muscles (CFEOM)	Q13509 (related)
H00268	Lissencephaly (LIS)	Q71U36 (related)