KNApSAcK Metabolite C00001215
Metabolite
KNApSAcK Entry
| id | C00001215 |
|---|---|
| Name | (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid |
| CAS RN | 1553-41-9 |
| Standard InChI | InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15- |
| Standard InChI (Main Layer) | InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22) |
Cluster
| Phytochemical cluster | No. 50 |
|---|---|
| KCF-S cluster | No. 2002 |
Link
ChEMBL
| By standard InChI | CHEMBL460026 |
|---|---|
| By standard InChI Main Layer | CHEMBL460026 |
KEGG
| By LinkDB | C06428 |
|---|
CTD
| By CAS RN | D015118 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Palmariaceae | 1 |
| Ceramiaceae | 1 |
| Gigartinaceae | 1 |
| Dumontiaceae | 1 |
List (4)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Chondrus yendoi | 38505 | Gigartinaceae | Eukaryota | |
| Neodilsea yendoana | 142541 | Dumontiaceae | Eukaryota | |
| Palmaria palmata | 2822 | Palmariaceae | Eukaryota | |
| Ptilota filicina | 153248 | Ceramiaceae | Eukaryota |
Human Protein / Gene in interaction
12 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | CHEMBL460026 |
CHEMBL1794499
(1)
|
2 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | CHEMBL460026 |
CHEMBL1794311
(1)
|
2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL460026 |
CHEMBL1614458
(1)
|
0 / 0 |
| Q9UGP5 | DNA polymerase lambda | Enzyme | CHEMBL460026 |
CHEMBL1921596
(1)
CHEMBL1920071
(1)
|
0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL460026 |
CHEMBL1614410
(1)
|
1 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | CHEMBL460026 |
CHEMBL1794467
(1)
|
0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | CHEMBL460026 |
CHEMBL976708
(1)
CHEMBL976710
(1)
CHEMBL976711 (1) |
2 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | CHEMBL460026 |
CHEMBL2072929
(1)
|
5 / 3 |
| P13726 | Tissue factor | Membrane receptor | CHEMBL460026 |
CHEMBL995691
(1)
|
0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | CHEMBL460026 |
CHEMBL1794536
(1)
CHEMBL1921592
(1)
CHEMBL1921595 (1) |
0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | CHEMBL460026 |
CHEMBL1738442
(1)
|
0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | CHEMBL460026 |
CHEMBL2114738
(1)
|
0 / 0 |
CTD interaction (61)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D015118 | 19 |
ABCA1
ABC-1 ABC1 CERP HDLDT1 TGD |
ATP-binding cassette, sub-family A (ABC1), member 1 | Eicosapentaenoic Acid results in decreased expression of ABCA1 mRNA |
decreases expression
|
mRNA |
16730733
|
| D015118 | 9619 |
ABCG1
ABC8 WHITE1 |
ATP-binding cassette, sub-family G (WHITE), member 1 | Eicosapentaenoic Acid results in decreased expression of ABCG1 mRNA |
decreases expression
|
mRNA |
16730733
|
| D015118 | 9619 |
ABCG1
ABC8 WHITE1 |
ATP-binding cassette, sub-family G (WHITE), member 1 | Eicosapentaenoic Acid results in decreased expression of ABCG1 protein |
decreases expression
|
protein |
16730733
|
| D015118 | 9370 |
ADIPOQ
ACDC ACRP30 ADIPQTL1 ADPN APM-1 APM1 GBP28 |
adiponectin, C1Q and collagen domain containing | Eicosapentaenoic Acid results in increased expression of and results in increased secretion of ADIPOQ protein |
increases expression
/ increases secretion |
protein |
20814411
|
| D015118 | 9370 |
ADIPOQ
ACDC ACRP30 ADIPQTL1 ADPN APM-1 APM1 GBP28 |
adiponectin, C1Q and collagen domain containing | Eicosapentaenoic Acid results in increased secretion of ADIPOQ protein |
increases secretion
|
protein |
20814411
|
| D015118 | 338 |
APOB
FLDB LDLCQ4 |
apolipoprotein B | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein |
affects cotreatment
/ decreases expression |
protein |
17237316
|
| D015118 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | [Eicosapentaenoic Acid co-treated with Butyrates] results in increased activity of CASP3 protein |
affects cotreatment
/ increases activity |
protein |
19116882
|
| D015118 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]] |
decreases reaction
/ increases expression |
mRNA |
15698426
|
| D015118 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15698426
|
| D015118 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] |
decreases reaction
/ increases expression |
protein |
15698426
|
| D015118 | 958 |
CD40
Bp50 CDW40 TNFRSF5 p50 |
CD40 molecule, TNF receptor superfamily member 5 | Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15684433
|
| D015118 | 1401 |
CRP
PTX1 |
C-reactive protein, pentraxin-related | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of CRP protein |
affects cotreatment
/ decreases expression |
protein |
17237316
|
| D015118 | 1535 |
CYBA
p22-PHOX |
cytochrome b-245, alpha polypeptide | Eicosapentaenoic Acid results in decreased expression of CYBA mRNA |
decreases expression
|
mRNA |
11172467
|
| D015118 | 1544 |
CYP1A2
CP12 P3-450 P450(PA) |
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | Eicosapentaenoic Acid results in decreased activity of CYP1A2 protein |
decreases activity
|
protein |
16978661
|
| D015118 | 1557 |
CYP2C19
CPCJ CYP2C P450C2C P450IIC19 |
cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | CYP2C19 protein results in increased metabolism of [Eicosapentaenoic Acid co-treated with NADP] |
affects cotreatment
/ increases metabolic processing |
protein |
16978661
|
| D015118 | 1557 |
CYP2C19
CPCJ CYP2C P450C2C P450IIC19 |
cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | Eicosapentaenoic Acid results in decreased activity of CYP2C19 protein |
decreases activity
|
protein |
16978661
|
| D015118 | 1559 |
CYP2C9
CPC9 CYP2C CYP2C10 CYPIIC9 P450IIC9 |
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | CYP2C9 protein results in increased metabolism of [Eicosapentaenoic Acid co-treated with NADP] |
affects cotreatment
/ increases metabolic processing |
protein |
16978661
|
| D015118 | 1559 |
CYP2C9
CPC9 CYP2C CYP2C10 CYPIIC9 P450IIC9 |
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | Eicosapentaenoic Acid results in decreased activity of CYP2C9 protein |
decreases activity
|
protein |
16978661
|
| D015118 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Eicosapentaenoic Acid results in decreased activity of CYP2E1 protein |
decreases activity
|
protein |
16978661
|
| D015118 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | Eicosapentaenoic Acid results in decreased activity of CYP3A4 protein |
decreases activity
|
protein |
16978661
|
| D015118 | 117159 |
DCD
AIDD DCD-1 DSEP HCAP PIF |
dermcidin | Eicosapentaenoic Acid inhibits the reaction [DCD protein results in increased expression of PSMA2 mRNA] |
decreases reaction
/ increases expression |
protein |
15451026
|
| D015118 | 117159 |
DCD
AIDD DCD-1 DSEP HCAP PIF |
dermcidin | Eicosapentaenoic Acid inhibits the reaction [DCD protein results in increased expression of PSMB5 mRNA] |
decreases reaction
/ increases expression |
protein |
15451026
|
| D015118 | 2729 |
GCLC
GCL GCS GLCL GLCLC |
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) | Eicosapentaenoic Acid results in increased activity of GCLC protein |
increases activity
|
protein |
17092368
|
| D015118 | 2729 |
GCLC
GCL GCS GLCL GLCLC |
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) | Eicosapentaenoic Acid results in increased expression of GCLC mRNA |
increases expression
|
mRNA |
17092368
|
| D015118 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Eicosapentaenoic Acid results in increased expression of HMOX1 mRNA |
increases expression
|
mRNA |
17092368
|
| D015118 | 3593 |
IL12B
CLMF CLMF2 IL-12B NKSF NKSF2 |
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] |
decreases reaction
/ increases expression |
mRNA |
15684433
|
| D015118 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | alpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]] |
decreases reaction
/ increases expression |
protein |
12573452
|
| D015118 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in increased expression of IL1B protein |
affects cotreatment
/ increases expression |
protein |
16305726
|
| D015118 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
12573452
|
| D015118 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Eicosapentaenoic Acid results in decreased expression of IL1B protein |
decreases expression
|
protein |
9415022
|
| D015118 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Masoprocol inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]] |
decreases reaction
/ increases expression |
protein |
12573452
|
| D015118 | 3558 |
IL2
IL-2 TCGF lymphokine |
interleukin 2 | Eicosapentaenoic Acid results in decreased expression of IL2 protein |
decreases expression
|
protein |
9415022
|
| D015118 | 3565 |
IL4
BCGF-1 BCGF1 BSF-1 BSF1 IL-4 |
interleukin 4 | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in decreased expression of IL4 protein |
affects cotreatment
/ decreases expression |
protein |
16305726
|
| D015118 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | [Polyphenols co-treated with Antioxidants co-treated with Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Medroxyprogesterone Acetate co-treated with celecoxib] results in decreased expression of IL6 |
affects cotreatment
/ decreases expression |
16702388
|
|
| D015118 | 3952 |
LEP
LEPD OB OBS |
leptin | Eicosapentaenoic Acid results in decreased expression of LEP mRNA |
decreases expression
|
mRNA |
15949695
|
| D015118 | 778733 | Eicosapentaenoic Acid results in decreased expression of PPAR mRNA |
decreases expression
|
mRNA |
15949695
|
||
| D015118 | 5465 |
PPARA
NR1C1 PPAR PPARalpha hPPAR |
peroxisome proliferator-activated receptor alpha | Eicosapentaenoic Acid binds to and results in increased activity of PPARA protein |
affects binding
/ increases activity |
protein |
10403814
|
| D015118 | 5465 |
PPARA
NR1C1 PPAR PPARalpha hPPAR |
peroxisome proliferator-activated receptor alpha | Eicosapentaenoic Acid results in increased expression of PPARA mRNA |
increases expression
|
mRNA |
11172467
|
| D015118 | 5465 |
PPARA
NR1C1 PPAR PPARalpha hPPAR |
peroxisome proliferator-activated receptor alpha | Eicosapentaenoic Acid results in increased expression of PPARA protein |
increases expression
|
protein |
11172467
|
| D015118 | 5467 |
PPARD
FAAR NR1C2 NUC1 NUCI NUCII PPARB |
peroxisome proliferator-activated receptor delta | Eicosapentaenoic Acid results in increased expression of PPARD mRNA |
increases expression
|
mRNA |
11172467
|
| D015118 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Eicosapentaenoic Acid results in increased activity of PPARG protein] |
decreases reaction
/ increases activity |
protein |
15698426
|
| D015118 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Eicosapentaenoic Acid results in increased activity of PPARG protein |
increases activity
|
protein |
15698426
|
| D015118 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Eicosapentaenoic Acid results in increased expression of PPARG mRNA |
increases expression
|
mRNA |
11172467
15698426 |
| D015118 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Eicosapentaenoic Acid results in increased expression of PPARG protein |
increases expression
|
protein |
11172467
|
| D015118 | 10891 |
PPARGC1A
LEM6 PGC-1(alpha) PGC-1v PGC1 PGC1A PPARGC1 |
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | Eicosapentaenoic Acid results in increased expression of PPARGC1A mRNA |
increases expression
|
mRNA |
23056435
|
| D015118 | 5683 |
PSMA2
HC3 MU PMSA2 PSC2 |
proteasome (prosome, macropain) subunit, alpha type, 2 (EC:3.4.25.1) | Eicosapentaenoic Acid inhibits the reaction [DCD protein results in increased expression of PSMA2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15451026
|
| D015118 | 5693 |
PSMB5
LMPX MB1 X |
proteasome (prosome, macropain) subunit, beta type, 5 (EC:3.4.25.1) | Eicosapentaenoic Acid inhibits the reaction [DCD protein results in increased expression of PSMB5 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15451026
|
| D015118 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | alpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]] |
decreases reaction
/ increases expression |
protein |
12573452
|
| D015118 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
12573452
|
| D015118 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15684433
|
| D015118 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Eicosapentaenoic Acid results in increased expression of PTGS2 mRNA |
increases expression
|
mRNA |
17092368
|
| D015118 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Masoprocol inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]] |
decreases reaction
/ increases expression |
protein |
12573452
|
| D015118 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]] |
decreases reaction
/ increases activity |
protein |
15698426
|
| D015118 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein] |
decreases reaction
/ increases activity |
protein |
15698426
|
| D015118 | 56729 |
RETN
ADSF FIZZ3 RETN1 RSTN XCP1 |
resistin | Eicosapentaenoic Acid results in decreased expression of RETN mRNA |
decreases expression
|
mRNA |
15949695
|
| D015118 | 6647 |
SOD1
ALS ALS1 IPOA SOD hSod1 homodimer |
superoxide dismutase 1, soluble (EC:1.15.1.1) | Eicosapentaenoic Acid results in increased expression of SOD1 mRNA |
increases expression
|
mRNA |
11172467
|
| D015118 | 6647 |
SOD1
ALS ALS1 IPOA SOD hSod1 homodimer |
superoxide dismutase 1, soluble (EC:1.15.1.1) | Eicosapentaenoic Acid results in increased expression of SOD1 protein |
increases expression
|
protein |
11172467
|
| D015118 | 6720 |
SREBF1
SREBP-1c SREBP1 bHLHd1 |
sterol regulatory element binding transcription factor 1 | Eicosapentaenoic Acid results in decreased expression of SREBF1 mRNA |
decreases expression
|
mRNA |
15949695
|
| D015118 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Eicosapentaenoic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
decreases reaction
/ increases expression |
mRNA |
15684433
|
| D015118 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Eicosapentaenoic Acid results in decreased expression of TNF protein |
decreases expression
|
protein |
9415022
|
| D015118 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [Polyphenols co-treated with Antioxidants co-treated with Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Medroxyprogesterone Acetate co-treated with celecoxib] results in decreased expression of TNF |
affects cotreatment
/ decreases expression |
16702388
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #601665 | Obesity |
P37231
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (10)
| KEGG | disease name | UniProt |
|---|---|---|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
Diseases related to CTD interactions
17 disease from interactions of metabolites
| MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
|---|---|---|---|---|---|
| D000743 | D015118 | Anemia, Hemolytic |
marker/mechanism
|
12736713
|
|
| D001145 | D015118 | Arrhythmias, Cardiac |
therapeutic
|
15990700
|
|
| D002114 | D015118 | Calcinosis |
therapeutic
|
21193197
|
|
| D002318 | D015118 | Cardiovascular Diseases |
therapeutic
|
21193197
|
|
| D003327 | D015118 | Coronary Disease |
therapeutic
|
18986590
|
|
| D003866 | D015118 | Depressive Disorder |
therapeutic
|
11695079
|
|
| D050171 | D015118 | Dyslipidemias |
therapeutic
|
19277604
|
|
| D018149 | D015118 | Glucose Intolerance |
therapeutic
|
19277604
|
|
| D006973 | D015118 | Hypertension |
therapeutic
|
12661920
|
|
| D015228 | D015118 | Hypertriglyceridemia |
therapeutic
|
12661920
|
|
| D007333 | D015118 | Insulin Resistance |
therapeutic
|
10753628
19277604 |
|
| D007414 | D015118 | Intestinal Neoplasms |
therapeutic
|
11714441
|
|
| D048629 | D015118 | Micronuclei, Chromosome-Defective |
therapeutic
|
20052769
|
|
| D010146 | D015118 | Pain |
therapeutic
|
17038422
|
|
| D010300 | D015118 | Parkinson Disease |
therapeutic
|
20868657
|
|
| D012559 | D015118 | Schizophrenia |
therapeutic
|
14623502
|
|
| D013927 | D015118 | Thrombosis |
therapeutic
|
15990700
|