PCIDB

KNApSAcK Metabolite C00001308

Metabolite

KNApSAcK Entry

id C00001308
Name Ethyl acetate
CAS RN 141-78-6
Standard InChI InChI=1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
Standard InChI (Main Layer) InChI=1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3

Cluster

Phytochemical cluster
KCF-S cluster No. 4274

Link

ChEMBL

By standard InChI CHEMBL14152
By standard InChI Main Layer CHEMBL14152

KEGG

By LinkDB C00849

CTD

By CAS RN C007650

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P02545 Prelamin-A/C Unclassified protein CHEMBL14152 CHEMBL1614544 (1)
11 / 10
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL14152 CHEMBL1614458 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL14152 CHEMBL2114931 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL14152 CHEMBL1613910 (1) CHEMBL1614227 (1)
3 / 3

CTD interaction (4)

compound gene gene name gene description interaction interaction type form reference
pmid
C007650 6352 CCL5
D17S136E
RANTES
SCYA5
SIS-delta
SISd
TCP228
eoCP
chemokine (C-C motif) ligand 5 ethyl acetate results in increased expression of CCL5 protein increases expression
protein 11306435
C007650 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) ethyl acetate results in increased expression of CSF2 protein increases expression
protein 11306435
C007650 4790 NFKB1
EBP-1
KBF1
NF-kB1
NF-kappa-B
NF-kappaB
NFKB-p105
NFKB-p50
NFkappaB
p105
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 ethyl acetate results in increased localization of and results in increased activity of NFKB1 protein increases activity
/ increases localization
protein 11306435
C007650 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A ethyl acetate results in increased localization of and results in increased activity of RELA protein increases activity
/ increases localization
protein 11306435

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (13)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)