id | C00001337 |
---|---|
Name | gamma-Aminobutyric acid |
CAS RN | 56-12-2 |
Standard InChI | InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) |
Standard InChI (Main Layer) | InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) |
Phytochemical cluster | |
---|---|
KCF-S cluster | No. 3932 |
By standard InChI | CHEMBL96 |
---|---|
By standard InChI Main Layer | CHEMBL96 |
By LinkDB | C00334 |
---|
By CAS RN | D005680 |
---|
class name | count |
---|---|
rosids | 4 |
family name | count |
---|---|
Fabaceae | 3 |
Enterobacteriaceae | 1 |
Brassicaceae | 1 |
KNApSAcK organism | *ID | *family | *plant class | *kingdom |
---|---|---|---|---|
Arabidopsis thaliana | 3702 | Brassicaceae | rosids | Viridiplantae |
Escherichia coli K12 | 83333 | Enterobacteriaceae | Bacteria | |
Phaseolus spp. | 3883 | Fabaceae | rosids | Viridiplantae |
Pisum spp. | 3887 | Fabaceae | rosids | Viridiplantae |
Vicia spp. | 3904 | Fabaceae | rosids | Viridiplantae |
accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|---|
P48066 | Sodium- and chloride-dependent GABA transporter 3 | GABA | CHEMBL96 |
CHEMBL679557
(1)
|
0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL96 |
CHEMBL1741321
(1)
|
1 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | CHEMBL96 |
CHEMBL1738312
(1)
|
0 / 0 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | CHEMBL96 |
CHEMBL1794499
(2)
|
2 / 0 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | CHEMBL96 |
CHEMBL1738091
(1)
|
0 / 0 |
P30531 | Sodium- and chloride-dependent GABA transporter 1 | GABA | CHEMBL96 |
CHEMBL806333
(1)
|
0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | CHEMBL96 |
CHEMBL1614544
(2)
|
11 / 10 |
P23415 | Glycine receptor subunit alpha-1 | GLR alpha | CHEMBL96 |
CHEMBL896290
(1)
|
1 / 1 |
P16473 | Thyrotropin receptor | Glycohormone receptor | CHEMBL96 |
CHEMBL1614361
(1)
|
3 / 2 |
P10828 | Thyroid hormone receptor beta | NR1A2 | CHEMBL96 |
CHEMBL1613776
(1)
|
3 / 1 |
P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL678325 (1) CHEMBL680295 (1) CHEMBL894099 (2) CHEMBL894100 (1) CHEMBL966814 (1) |
1 / 1 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL96 |
CHEMBL1741325
(1)
|
0 / 1 |
P24046 | Gamma-aminobutyric acid receptor subunit rho-1 | GABA-A rho | CHEMBL96 |
CHEMBL679662
(1)
CHEMBL945996
(1)
CHEMBL964513 (1) CHEMBL2317988 (2) CHEMBL2340050 (1) |
0 / 0 |
P54132 | Bloom syndrome protein | Enzyme | CHEMBL96 |
CHEMBL1614522
(1)
CHEMBL1614067
(1)
|
1 / 2 |
P48065 | Sodium- and chloride-dependent betaine transporter | Betaine and GABA Na-symporter | CHEMBL96 |
CHEMBL806334
(1)
|
0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | CHEMBL96 |
CHEMBL1738606
(1)
|
0 / 0 |
O75496 | Geminin | Unclassified protein | CHEMBL96 |
CHEMBL2114780
(1)
|
0 / 0 |
P46098 | 5-hydroxytryptamine receptor 3A | NS | CHEMBL96 |
CHEMBL896288
(1)
|
0 / 0 |
P11308 | Transcriptional regulator ERG | Unclassified protein | CHEMBL96 |
CHEMBL2114924
(1)
|
1 / 2 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL96 |
CHEMBL1614410
(1)
|
1 / 3 |
P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | CHEMBL96 |
CHEMBL858748
(1)
CHEMBL2208624
(1)
|
1 / 1 |
Q9UBS5 | Gamma-aminobutyric acid type B receptor subunit 1 | GABA-B receptor | CHEMBL96 |
CHEMBL682871
(1)
CHEMBL964516
(1)
CHEMBL2331015 (1) |
0 / 0 |
P36544 | Neuronal acetylcholine receptor subunit alpha-7 | CHRN alpha | CHEMBL96 |
CHEMBL896286
(1)
|
0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL96 |
CHEMBL1741322
(1)
|
0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL96 |
CHEMBL1737868
(1)
|
0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL96 |
CHEMBL1741323
(1)
|
1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL96 |
CHEMBL1741324
(1)
|
0 / 1 |
Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | CHEMBL96 |
CHEMBL1614052
(1)
|
1 / 0 |
Q7Z2H8 | Proton-coupled amino acid transporter 1 | Unclassified protein | CHEMBL96 |
CHEMBL1919336
(2)
|
0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | CHEMBL96 |
CHEMBL1738442
(3)
|
0 / 0 |
Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) |
0 / 0 |
P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | CHEMBL96 |
CHEMBL683049
(1)
CHEMBL683054
(1)
CHEMBL681334 (1) CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL678325 (1) CHEMBL680295 (1) CHEMBL682715 (1) CHEMBL683016 (1) CHEMBL682825 (1) CHEMBL681091 (1) CHEMBL681094 (1) CHEMBL682902 (1) CHEMBL679474 (1) CHEMBL685341 (1) CHEMBL682418 (1) |
1 / 0 |
P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL681094 (1) CHEMBL682902 (1) |
0 / 0 |
O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) |
1 / 1 |
P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL679474 (1) CHEMBL685341 (1) |
0 / 0 |
Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) |
0 / 0 |
P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) |
0 / 0 |
Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) |
0 / 0 |
P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL682825 (1) CHEMBL681091 (1) |
0 / 0 |
O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) |
0 / 0 |
P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL894099 (2) CHEMBL894100 (1) |
0 / 0 |
P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | CHEMBL96 |
CHEMBL683049
(1)
CHEMBL683054
(1)
CHEMBL681334 (1) CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL678325 (1) CHEMBL680295 (1) CHEMBL682715 (1) CHEMBL683016 (1) CHEMBL682825 (1) CHEMBL681091 (1) CHEMBL681094 (1) CHEMBL682902 (1) CHEMBL679474 (1) CHEMBL685341 (1) CHEMBL682418 (1) CHEMBL894099 (2) CHEMBL894100 (1) |
4 / 2 |
P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) |
0 / 0 |
Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | CHEMBL96 |
CHEMBL683049
(1)
CHEMBL683054
(1)
CHEMBL681334 (1) CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL682418 (1) |
0 / 0 |
P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | CHEMBL96 |
CHEMBL683054
(1)
CHEMBL681334
(1)
CHEMBL681949 (1) CHEMBL681951 (1) CHEMBL682715 (1) CHEMBL683016 (1) |
1 / 0 |
A8MPY1 | Gamma-aminobutyric acid receptor subunit rho-3 | GABA-A rho | CHEMBL96 |
CHEMBL679662
(1)
|
0 / 0 |
P28476 | Gamma-aminobutyric acid receptor subunit rho-2 | GABA-A rho | CHEMBL96 |
CHEMBL679662
(1)
|
0 / 0 |
Q05BR4 | SLC16A10 protein | Unclassified protein | CHEMBL96 |
CHEMBL2076232
(1)
|
0 / 0 |
O75899 | Gamma-aminobutyric acid type B receptor subunit 2 | GABA-B receptor | CHEMBL96 |
CHEMBL682871
(1)
CHEMBL2331015
(1)
|
0 / 0 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | CHEMBL96 |
CHEMBL2354287
(1)
|
1 / 1 |
compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
---|---|---|---|---|---|---|---|
D005680 | 18 |
ABAT
GABA-AT GABAT NPD009 |
4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22) | [Vigabatrin results in decreased activity of ABAT protein] which results in increased abundance of gamma-Aminobutyric Acid |
decreases activity
/ increases abundance |
protein |
12748807
|
D005680 | 1138 |
CHRNA5
LNCR2 |
cholinergic receptor, nicotinic, alpha 5 (neuronal) | gamma-Aminobutyric Acid binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
8388298
|
D005680 | 1140 |
CHRNB1
ACHRB CHRNB CMS1D CMS2A SCCMS |
cholinergic receptor, nicotinic, beta 1 (muscle) | gamma-Aminobutyric Acid binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
8388298
|
D005680 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 protein promotes the reaction [Estradiol inhibits the reaction [Potassium results in increased secretion of gamma-Aminobutyric Acid]] |
decreases reaction
/ increases reaction / increases secretion |
protein |
19211896
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Chloral Hydrate inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
increases activity
/ increases reaction |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Chlorobutanol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Egtazic Acid inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Enflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Ether inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Fendiline inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein] |
affects binding
/ increases activity |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | gamma-Aminobutyric Acid results in increased activity of GABBR1 protein |
increases activity
|
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | gamma-Aminobutyric Acid results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein] |
affects binding
/ increases activity |
protein |
11125035
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Isoflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Methoxyflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | sevoflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | tert-Butyl Alcohol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
increases activity
/ increases reaction |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
increases activity
/ increases reaction |
protein |
10683198
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 2550 |
GABBR1
GABABR1 GABBR1-3 GB1 GPRC3A dJ271M21.1.1 dJ271M21.1.2 |
gamma-aminobutyric acid (GABA) B receptor, 1 | Trifluoroethanol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] |
decreases reaction
/ increases activity |
protein |
10683198
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ affects reaction / increases activity |
protein |
21729720
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15627515
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ affects reaction / increases activity |
protein |
21729720
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ increases activity / increases reaction |
protein |
21729720
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15627515
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
15627515
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | Egtazic Acid inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | Fendiline inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein] |
affects binding
/ increases activity |
protein |
15627515
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | gamma-Aminobutyric Acid results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein] |
affects binding
/ increases activity |
protein |
11125035
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein] |
affects cotreatment
/ increases activity |
protein |
21729720
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
21729720
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
21729720
|
D005680 | 9568 |
GABBR2
GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 |
gamma-aminobutyric acid (GABA) B receptor, 2 | Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
15627515
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10825391
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ affects reaction / increases activity |
protein |
21729720
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]] |
affects binding
/ affects reaction / increases activity |
protein |
11137757
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
20861069
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ affects reaction / increases activity |
protein |
21729720
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
20861069
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
20861069
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ increases activity / increases reaction |
protein |
21729720
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
15588619
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] |
affects binding
/ increases activity / increases reaction |
protein |
11156579
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
10825391
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
22547355
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]] |
affects binding
/ affects reaction / increases activity / increases reaction |
protein |
22547355
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | GABRA1 protein results in increased susceptibility to gamma-Aminobutyric Acid |
increases response to substance
|
protein |
15765150
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects reaction |
protein |
14637376
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
11812690
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein] |
affects binding
/ increases activity |
protein |
11137757
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases reaction |
protein |
21111751
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB3 protein]] |
affects binding
/ increases reaction |
protein |
21111751
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein] |
affects binding
/ increases activity |
protein |
10825391
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
20861069
22547355 |
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein] |
affects cotreatment
/ increases activity |
protein |
21729720
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Lindane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] |
affects binding
/ decreases reaction / increases activity |
protein |
11156579
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Lindane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Lindane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
21729720
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
21729720
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
22547355
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10825391
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10825391
|
D005680 | 2554 |
GABRA1
ECA4 EJM EJM5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 1 | Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
11812690
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein] |
affects binding
/ increases activity |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2555 |
GABRA2
|
gamma-aminobutyric acid (GABA) A receptor, alpha 2 | Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2557 |
GABRA4
|
gamma-aminobutyric acid (GABA) A receptor, alpha 4 | benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] |
affects binding
/ increases activity / increases reaction |
protein |
18762200
|
D005680 | 2557 |
GABRA4
|
gamma-aminobutyric acid (GABA) A receptor, alpha 4 | gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein] |
affects binding
/ increases activity |
protein |
18762200
|
D005680 | 2558 |
GABRA5
|
gamma-aminobutyric acid (GABA) A receptor, alpha 5 | GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects reaction / increases activity |
protein |
10987858
|
D005680 | 2559 |
GABRA6
|
gamma-aminobutyric acid (GABA) A receptor, alpha 6 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2559 |
GABRA6
|
gamma-aminobutyric acid (GABA) A receptor, alpha 6 | Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
8632757
|
D005680 | 2559 |
GABRA6
|
gamma-aminobutyric acid (GABA) A receptor, alpha 6 | gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
9316872
|
D005680 | 2559 |
GABRA6
|
gamma-aminobutyric acid (GABA) A receptor, alpha 6 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2559 |
GABRA6
|
gamma-aminobutyric acid (GABA) A receptor, alpha 6 | Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
8632757
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10825391
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] |
affects binding
/ increases activity / increases reaction |
protein |
11156579
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
10825391
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases reaction |
protein |
21111751
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein] |
affects binding
/ increases activity |
protein |
10825391
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein] |
affects binding
/ increases activity |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] |
affects binding
/ decreases reaction / increases activity |
protein |
11156579
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10825391
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10825391
|
D005680 | 2560 |
GABRB1
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 | Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
10683198
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]] |
affects binding
/ affects reaction / increases activity |
protein |
11137757
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
20861069
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
20861069
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
20861069
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
15588619
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
22547355
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]] |
affects binding
/ affects reaction / increases activity / increases reaction |
protein |
22547355
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects reaction / increases activity |
protein |
10987858
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects reaction |
protein |
14637376
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
11812690
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein] |
affects binding
/ increases activity |
protein |
11137757
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides] |
increases reaction
/ increases transport |
protein |
8161449
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
20861069
22547355 |
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]] |
increases reaction
/ increases transport |
protein |
8161449
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
22547355
|
D005680 | 2561 |
GABRB2
|
gamma-aminobutyric acid (GABA) A receptor, beta 2 | Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
11812690
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] |
affects binding
/ increases activity / increases reaction |
protein |
18762200
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
8632757
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB3 protein]] |
affects binding
/ increases reaction |
protein |
21111751
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides] |
increases reaction
/ increases transport |
protein |
8161449
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein] |
affects binding
/ increases activity |
protein |
18762200
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Lindane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Lindane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Lindane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]] |
increases reaction
/ increases transport |
protein |
8161449
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2562 |
GABRB3
ECA5 |
gamma-aminobutyric acid (GABA) A receptor, beta 3 | Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
8632757
|
D005680 | 2563 |
GABRD
EIG10 EJM7 GEFSP5 |
gamma-aminobutyric acid (GABA) A receptor, delta | benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] |
affects binding
/ increases activity / increases reaction |
protein |
18762200
|
D005680 | 2563 |
GABRD
EIG10 EJM7 GEFSP5 |
gamma-aminobutyric acid (GABA) A receptor, delta | gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein] |
affects binding
/ increases activity |
protein |
18762200
|
D005680 | 2564 |
GABRE
|
gamma-aminobutyric acid (GABA) A receptor, epsilon | Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2564 |
GABRE
|
gamma-aminobutyric acid (GABA) A receptor, epsilon | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2564 |
GABRE
|
gamma-aminobutyric acid (GABA) A receptor, epsilon | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ affects reaction / increases activity |
protein |
21729720
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]] |
affects binding
/ affects reaction / increases activity |
protein |
11137757
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
20861069
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ affects cotreatment / increases activity |
protein |
20819908
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ affects reaction / increases activity |
protein |
21729720
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
20861069
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
20861069
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ increases activity / increases reaction |
protein |
21729720
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
15588619
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] |
affects binding
/ increases activity / increases reaction |
protein |
11156579
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABRG2 protein] |
increases activity
/ increases reaction |
protein |
10797553
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
22547355
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
8632757
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]] |
affects binding
/ affects reaction / increases activity / increases reaction |
protein |
22547355
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects reaction / increases activity |
protein |
10987858
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ affects reaction |
protein |
14637376
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
11812690
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein] |
affects binding
/ increases activity |
protein |
11137757
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
20861069
22547355 |
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein] |
affects cotreatment
/ increases activity |
protein |
21729720
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein] |
affects binding
/ increases activity |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | gamma-Aminobutyric Acid results in increased activity of GABRG2 protein |
increases activity
|
protein |
10797553
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Lindane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] |
affects binding
/ decreases reaction / increases activity |
protein |
11156579
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Lindane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Lindane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
15588619
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
21729720
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
21729720
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ decreases reaction / increases activity |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ affects cotreatment / increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] |
affects binding
/ increases activity / increases reaction |
10049148
|
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
9316872
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
8632757
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
22547355
|
D005680 | 2566 |
GABRG2
CAE2 ECA2 GEFSP3 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 | Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] |
affects binding
/ increases activity / increases reaction |
protein |
11812690
|
D005680 | 2571 |
GAD1
CPSQ1 GAD SCP |
glutamate decarboxylase 1 (brain, 67kDa) (EC:4.1.1.15) | GAD1 protein results in increased chemical synthesis of gamma-Aminobutyric Acid |
increases chemical synthesis
|
protein |
15571623
|
D005680 | 6529 |
SLC6A1
GABATHG GABATR GAT1 |
solute carrier family 6 (neurotransmitter transporter), member 1 | Niflumic Acid inhibits the reaction [SLC6A1 protein results in increased uptake of gamma-Aminobutyric Acid] |
decreases reaction
/ increases uptake |
protein |
15981712
|
D005680 | 6529 |
SLC6A1
GABATHG GABATR GAT1 |
solute carrier family 6 (neurotransmitter transporter), member 1 | SLC6A1 protein results in increased uptake of gamma-Aminobutyric Acid |
increases uptake
|
protein |
15981712
|
D005680 | 6529 |
SLC6A1
GABATHG GABATR GAT1 |
solute carrier family 6 (neurotransmitter transporter), member 1 | SLC6A1 results in increased export of gamma-Aminobutyric Acid |
increases export
|
21748804
|
|
D005680 | 6538 |
SLC6A11
GAT-3 GAT3 GAT4 |
solute carrier family 6 (neurotransmitter transporter), member 11 | SLC6A11 results in increased export of gamma-Aminobutyric Acid |
increases export
|
21748804
|
|
D005680 | 6540 |
SLC6A13
GAT-2 GAT2 GAT3 |
solute carrier family 6 (neurotransmitter transporter), member 13 | SLC6A13 results in increased export of gamma-Aminobutyric Acid |
increases export
|
21748804
|
OMIM | preferred title | UniProt |
---|---|---|
#103780 | Alcohol dependence |
P47869
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
#210900 | Bloom syndrome; blm |
P54132
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#607208 | Dravet syndrome |
P18507
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
#612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
#613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
#611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
#612219 | Ewing sarcoma; es |
P11308
|
#613163 | Gaba-transaminase deficiency |
P80404
|
#604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
#611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#149400 | Hyperekplexia, hereditary 1; hkpx1 |
P23415
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG | disease name | UniProt |
---|---|---|
H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00024 | Prostate cancer |
P11308
(related)
|
H00035 | Ewing's sarcoma |
P11308
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H00769 | Hyperekplexia |
P23415
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
|
H01257 | GABA-transaminase deficiency |
P80404
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
---|---|---|---|---|---|
D001259 | D005680 | Ataxia |
marker/mechanism
|
19747469
|
|
D001919 | D005680 | Bradycardia |
marker/mechanism
therapeutic |
1451572
2867949 6621821 9309312 |
|
D002375 | D005680 | Catalepsy |
marker/mechanism
|
707139
6771794 |
|
D002389 | D005680 | Catatonia |
marker/mechanism
therapeutic |
2823166
3938209 |
|
D019970 | D005680 | Cocaine-Related Disorders |
marker/mechanism
|
15135161
|
|
D064420 | D005680 | Drug-Related Side Effects and Adverse Reactions |
therapeutic
|
6872331
|
|
D004827 | D005680 | Epilepsy |
marker/mechanism
therapeutic |
10219272
19474175 |
|
D006429 | D005680 | Hemiplegia |
marker/mechanism
|
3683725
|
|
D006973 | D005680 | Hypertension |
marker/mechanism
therapeutic |
10524271
11529687 |
|
D007022 | D005680 | Hypotension |
marker/mechanism
|
1451572
6621821 |
|
D020149 | D005680 | Manganese Poisoning |
marker/mechanism
|
18771689
|
|
D009069 | D005680 | Movement Disorders |
marker/mechanism
|
2727012
|
|
D012559 | D005680 | Schizophrenia |
marker/mechanism
|
18757185
|
|
D012640 | D005680 | Seizures |
marker/mechanism
therapeutic |
1665475
6872331 7073000 7463050 9030893 9249254 11587709 |
|
D013226 | D005680 | Status Epilepticus |
marker/mechanism
therapeutic |
1969357
8474571 8817469 |
|
D013375 | D005680 | Substance Withdrawal Syndrome |
marker/mechanism
|
10690749
|
|
D013610 | D005680 | Tachycardia |
marker/mechanism
|
2541852
|