Metabolite

KNApSAcK Entry

id C00001337
Name gamma-Aminobutyric acid
CAS RN 56-12-2
Standard InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
Standard InChI (Main Layer) InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)

Cluster

Phytochemical cluster
KCF-S cluster No. 3932

Link

ChEMBL

By standard InChI CHEMBL96
By standard InChI Main Layer CHEMBL96

KEGG

By LinkDB C00334

CTD

By CAS RN D005680

Human Protein / Gene in interaction

50 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P48066 Sodium- and chloride-dependent GABA transporter 3 GABA CHEMBL96 CHEMBL679557 (1)
0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL96 CHEMBL1741321 (1)
1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL96 CHEMBL1738312 (1)
0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL96 CHEMBL1794499 (2)
2 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL96 CHEMBL1738091 (1)
0 / 0
P30531 Sodium- and chloride-dependent GABA transporter 1 GABA CHEMBL96 CHEMBL806333 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL96 CHEMBL1614544 (2)
11 / 10
P23415 Glycine receptor subunit alpha-1 GLR alpha CHEMBL96 CHEMBL896290 (1)
1 / 1
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL96 CHEMBL1614361 (1)
3 / 2
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL96 CHEMBL1613776 (1)
3 / 1
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
CHEMBL678325 (1) CHEMBL680295 (1)
CHEMBL894099 (2) CHEMBL894100 (1)
CHEMBL966814 (1)
1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL96 CHEMBL1741325 (1)
0 / 1
P24046 Gamma-aminobutyric acid receptor subunit rho-1 GABA-A rho CHEMBL96 CHEMBL679662 (1) CHEMBL945996 (1)
CHEMBL964513 (1) CHEMBL2317988 (2)
CHEMBL2340050 (1)
0 / 0
P54132 Bloom syndrome protein Enzyme CHEMBL96 CHEMBL1614522 (1) CHEMBL1614067 (1)
1 / 2
P48065 Sodium- and chloride-dependent betaine transporter Betaine and GABA Na-symporter CHEMBL96 CHEMBL806334 (1)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL96 CHEMBL1738606 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL96 CHEMBL2114780 (1)
0 / 0
P46098 5-hydroxytryptamine receptor 3A NS CHEMBL96 CHEMBL896288 (1)
0 / 0
P11308 Transcriptional regulator ERG Unclassified protein CHEMBL96 CHEMBL2114924 (1)
1 / 2
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL96 CHEMBL1614410 (1)
1 / 3
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase CHEMBL96 CHEMBL858748 (1) CHEMBL2208624 (1)
1 / 1
Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 GABA-B receptor CHEMBL96 CHEMBL682871 (1) CHEMBL964516 (1)
CHEMBL2331015 (1)
0 / 0
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha CHEMBL96 CHEMBL896286 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL96 CHEMBL1741322 (1)
0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL96 CHEMBL1737868 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL96 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL96 CHEMBL1741324 (1)
0 / 1
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor CHEMBL96 CHEMBL1614052 (1)
1 / 0
Q7Z2H8 Proton-coupled amino acid transporter 1 Unclassified protein CHEMBL96 CHEMBL1919336 (2)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL96 CHEMBL1738442 (3)
0 / 0
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta CHEMBL96 CHEMBL683049 (1) CHEMBL683054 (1)
CHEMBL681334 (1) CHEMBL681949 (1)
CHEMBL681951 (1) CHEMBL678325 (1)
CHEMBL680295 (1) CHEMBL682715 (1)
CHEMBL683016 (1) CHEMBL682825 (1)
CHEMBL681091 (1) CHEMBL681094 (1)
CHEMBL682902 (1) CHEMBL679474 (1)
CHEMBL685341 (1) CHEMBL682418 (1)
1 / 0
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
CHEMBL681094 (1) CHEMBL682902 (1)
0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
CHEMBL679474 (1) CHEMBL685341 (1)
0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
CHEMBL682825 (1) CHEMBL681091 (1)
0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
CHEMBL894099 (2) CHEMBL894100 (1)
0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma CHEMBL96 CHEMBL683049 (1) CHEMBL683054 (1)
CHEMBL681334 (1) CHEMBL681949 (1)
CHEMBL681951 (1) CHEMBL678325 (1)
CHEMBL680295 (1) CHEMBL682715 (1)
CHEMBL683016 (1) CHEMBL682825 (1)
CHEMBL681091 (1) CHEMBL681094 (1)
CHEMBL682902 (1) CHEMBL679474 (1)
CHEMBL685341 (1) CHEMBL682418 (1)
CHEMBL894099 (2) CHEMBL894100 (1)
4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha CHEMBL96 CHEMBL683049 (1) CHEMBL683054 (1)
CHEMBL681334 (1) CHEMBL681949 (1)
CHEMBL681951 (1) CHEMBL682418 (1)
0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha CHEMBL96 CHEMBL683054 (1) CHEMBL681334 (1)
CHEMBL681949 (1) CHEMBL681951 (1)
CHEMBL682715 (1) CHEMBL683016 (1)
1 / 0
A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3 GABA-A rho CHEMBL96 CHEMBL679662 (1)
0 / 0
P28476 Gamma-aminobutyric acid receptor subunit rho-2 GABA-A rho CHEMBL96 CHEMBL679662 (1)
0 / 0
Q05BR4 SLC16A10 protein Unclassified protein CHEMBL96 CHEMBL2076232 (1)
0 / 0
O75899 Gamma-aminobutyric acid type B receptor subunit 2 GABA-B receptor CHEMBL96 CHEMBL682871 (1) CHEMBL2331015 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL96 CHEMBL2354287 (1)
1 / 1

CTD interaction (269)

compound gene gene name gene description interaction interaction type form reference
pmid
D005680 18 ABAT
GABA-AT
GABAT
NPD009
4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22) [Vigabatrin results in decreased activity of ABAT protein] which results in increased abundance of gamma-Aminobutyric Acid decreases activity
/ increases abundance
protein 12748807
D005680 1138 CHRNA5
LNCR2
cholinergic receptor, nicotinic, alpha 5 (neuronal) gamma-Aminobutyric Acid binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] affects binding
/ affects cotreatment
/ increases activity
protein 8388298
D005680 1140 CHRNB1
ACHRB
CHRNB
CMS1D
CMS2A
SCCMS
cholinergic receptor, nicotinic, beta 1 (muscle) gamma-Aminobutyric Acid binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] affects binding
/ affects cotreatment
/ increases activity
protein 8388298
D005680 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 protein promotes the reaction [Estradiol inhibits the reaction [Potassium results in increased secretion of gamma-Aminobutyric Acid]] decreases reaction
/ increases reaction
/ increases secretion
protein 19211896
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Chloral Hydrate inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] increases activity
/ increases reaction
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Chlorobutanol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Egtazic Acid inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Enflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Ether inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Fendiline inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein] affects binding
/ increases activity
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 gamma-Aminobutyric Acid results in increased activity of GABBR1 protein increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 gamma-Aminobutyric Acid results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein] affects binding
/ increases activity
protein 11125035
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Isoflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Methoxyflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 sevoflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 tert-Butyl Alcohol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] increases activity
/ increases reaction
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] increases activity
/ increases reaction
protein 10683198
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 2550 GABBR1
GABABR1
GABBR1-3
GB1
GPRC3A
dJ271M21.1.1
dJ271M21.1.2
gamma-aminobutyric acid (GABA) B receptor, 1 Trifluoroethanol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] decreases reaction
/ increases activity
protein 10683198
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ affects reaction
/ increases activity
protein 21729720
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15627515
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ affects reaction
/ increases activity
protein 21729720
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ increases activity
/ increases reaction
protein 21729720
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15627515
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15627515
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 Egtazic Acid inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 Fendiline inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein] affects binding
/ increases activity
protein 15627515
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 gamma-Aminobutyric Acid results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein] affects binding
/ increases activity
protein 11125035
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein] affects cotreatment
/ increases activity
protein 21729720
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ decreases reaction
/ increases activity
protein 21729720
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ decreases reaction
/ increases activity
protein 21729720
D005680 9568 GABBR2
GABABR2
GPR51
GPRC3B
HG20
HRIHFB2099
gamma-aminobutyric acid (GABA) B receptor, 2 Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 15627515
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10825391
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ affects reaction
/ increases activity
protein 21729720
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]] affects binding
/ affects reaction
/ increases activity
protein 11137757
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 20861069
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ affects reaction
/ increases activity
protein 21729720
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 20861069
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 20861069
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ increases activity
/ increases reaction
protein 21729720
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15588619
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] affects binding
/ increases activity
/ increases reaction
protein 11156579
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 10825391
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 22547355
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]] affects binding
/ affects reaction
/ increases activity
/ increases reaction
protein 22547355
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 GABRA1 protein results in increased susceptibility to gamma-Aminobutyric Acid increases response to substance
protein 15765150
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects reaction
protein 14637376
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 11812690
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein] affects binding
/ increases activity
protein 11137757
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases reaction
protein 21111751
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB3 protein]] affects binding
/ increases reaction
protein 21111751
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein] affects binding
/ increases activity
protein 10825391
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 20861069
22547355
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein] affects cotreatment
/ increases activity
protein 21729720
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Lindane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] affects binding
/ decreases reaction
/ increases activity
protein 11156579
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Lindane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Lindane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ decreases reaction
/ increases activity
protein 21729720
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ decreases reaction
/ increases activity
protein 21729720
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 22547355
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10825391
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10825391
D005680 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 11812690
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein] affects binding
/ increases activity
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2555 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2 Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2557 GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4 benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] affects binding
/ increases activity
/ increases reaction
protein 18762200
D005680 2557 GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4 gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein] affects binding
/ increases activity
protein 18762200
D005680 2558 GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5 GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects reaction
/ increases activity
protein 10987858
D005680 2559 GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2559 GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6 Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 8632757
D005680 2559 GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6 gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 9316872
D005680 2559 GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2559 GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6 Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 8632757
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10825391
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] affects binding
/ increases activity
/ increases reaction
protein 11156579
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 10825391
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases reaction
protein 21111751
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein] affects binding
/ increases activity
protein 10825391
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein] affects binding
/ increases activity
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] affects binding
/ decreases reaction
/ increases activity
protein 11156579
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10825391
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10825391
D005680 2560 GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1 Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] affects binding
/ increases activity
/ increases reaction
protein 10683198
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]] affects binding
/ affects reaction
/ increases activity
protein 11137757
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 20861069
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 20861069
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 20861069
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15588619
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 22547355
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]] affects binding
/ affects reaction
/ increases activity
/ increases reaction
protein 22547355
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects reaction
/ increases activity
protein 10987858
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects reaction
protein 14637376
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 11812690
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein] affects binding
/ increases activity
protein 11137757
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides] increases reaction
/ increases transport
protein 8161449
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 20861069
22547355
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]] increases reaction
/ increases transport
protein 8161449
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 22547355
D005680 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 11812690
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] affects binding
/ increases activity
/ increases reaction
protein 18762200
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 8632757
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB3 protein]] affects binding
/ increases reaction
protein 21111751
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides] increases reaction
/ increases transport
protein 8161449
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein] affects binding
/ increases activity
protein 18762200
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Lindane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Lindane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Lindane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]] increases reaction
/ increases transport
protein 8161449
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2562 GABRB3
ECA5
gamma-aminobutyric acid (GABA) A receptor, beta 3 Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 8632757
D005680 2563 GABRD
EIG10
EJM7
GEFSP5
gamma-aminobutyric acid (GABA) A receptor, delta benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]] affects binding
/ increases activity
/ increases reaction
protein 18762200
D005680 2563 GABRD
EIG10
EJM7
GEFSP5
gamma-aminobutyric acid (GABA) A receptor, delta gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein] affects binding
/ increases activity
protein 18762200
D005680 2564 GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2564 GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2564 GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ affects reaction
/ increases activity
protein 21729720
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]] affects binding
/ affects reaction
/ increases activity
protein 11137757
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 20861069
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ affects cotreatment
/ increases activity
protein 20819908
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ affects reaction
/ increases activity
protein 21729720
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 20861069
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 20861069
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ increases activity
/ increases reaction
protein 21729720
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15588619
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] affects binding
/ increases activity
/ increases reaction
protein 11156579
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABRG2 protein] increases activity
/ increases reaction
protein 10797553
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 22547355
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 8632757
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]] affects binding
/ affects reaction
/ increases activity
/ increases reaction
protein 22547355
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects reaction
/ increases activity
protein 10987858
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ affects reaction
protein 14637376
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 11812690
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein] affects binding
/ increases activity
protein 11137757
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 20861069
22547355
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein] affects cotreatment
/ increases activity
protein 21729720
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein] affects binding
/ increases activity
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 gamma-Aminobutyric Acid results in increased activity of GABRG2 protein increases activity
protein 10797553
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Lindane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]] affects binding
/ decreases reaction
/ increases activity
protein 11156579
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Lindane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Lindane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 15588619
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ decreases reaction
/ increases activity
protein 21729720
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] affects cotreatment
/ decreases reaction
/ increases activity
protein 21729720
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ affects cotreatment
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] affects binding
/ increases activity
/ increases reaction
10049148
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 9316872
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 8632757
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 22547355
D005680 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ increases activity
/ increases reaction
protein 11812690
D005680 2571 GAD1
CPSQ1
GAD
SCP
glutamate decarboxylase 1 (brain, 67kDa) (EC:4.1.1.15) GAD1 protein results in increased chemical synthesis of gamma-Aminobutyric Acid increases chemical synthesis
protein 15571623
D005680 6529 SLC6A1
GABATHG
GABATR
GAT1
solute carrier family 6 (neurotransmitter transporter), member 1 Niflumic Acid inhibits the reaction [SLC6A1 protein results in increased uptake of gamma-Aminobutyric Acid] decreases reaction
/ increases uptake
protein 15981712
D005680 6529 SLC6A1
GABATHG
GABATR
GAT1
solute carrier family 6 (neurotransmitter transporter), member 1 SLC6A1 protein results in increased uptake of gamma-Aminobutyric Acid increases uptake
protein 15981712
D005680 6529 SLC6A1
GABATHG
GABATR
GAT1
solute carrier family 6 (neurotransmitter transporter), member 1 SLC6A1 results in increased export of gamma-Aminobutyric Acid increases export
21748804
D005680 6538 SLC6A11
GAT-3
GAT3
GAT4
solute carrier family 6 (neurotransmitter transporter), member 11 SLC6A11 results in increased export of gamma-Aminobutyric Acid increases export
21748804
D005680 6540 SLC6A13
GAT-2
GAT2
GAT3
solute carrier family 6 (neurotransmitter transporter), member 13 SLC6A13 results in increased export of gamma-Aminobutyric Acid increases export
21748804

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (36)

OMIM preferred title UniProt
#103780 Alcohol dependence P47869
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#612219 Ewing sarcoma; es P11308
#613163 Gaba-transaminase deficiency P80404
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#149400 Hyperekplexia, hereditary 1; hkpx1 P23415
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (27)

KEGG disease name UniProt
H00783 Febrile seizures O14764 (related)
P18507 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H01205 Coumarin resistance P11712 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00769 Hyperekplexia P23415 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)

Diseases related to CTD interactions

17 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D001259 D005680 Ataxia marker/mechanism
19747469
D001919 D005680 Bradycardia marker/mechanism
therapeutic
1451572
2867949
6621821
9309312
D002375 D005680 Catalepsy marker/mechanism
707139
6771794
D002389 D005680 Catatonia marker/mechanism
therapeutic
2823166
3938209
D019970 D005680 Cocaine-Related Disorders marker/mechanism
15135161
D064420 D005680 Drug-Related Side Effects and Adverse Reactions therapeutic
6872331
D004827 D005680 Epilepsy marker/mechanism
therapeutic
10219272
19474175
D006429 D005680 Hemiplegia marker/mechanism
3683725
D006973 D005680 Hypertension marker/mechanism
therapeutic
10524271
11529687
D007022 D005680 Hypotension marker/mechanism
1451572
6621821
D020149 D005680 Manganese Poisoning marker/mechanism
18771689
D009069 D005680 Movement Disorders marker/mechanism
2727012
D012559 D005680 Schizophrenia marker/mechanism
18757185
D012640 D005680 Seizures marker/mechanism
therapeutic
1665475
6872331
7073000
7463050
9030893
9249254
11587709
D013226 D005680 Status Epilepticus marker/mechanism
therapeutic
1969357
8474571
8817469
D013375 D005680 Substance Withdrawal Syndrome marker/mechanism
10690749
D013610 D005680 Tachycardia marker/mechanism
2541852