Vicia spp.
Species
KNApSAcK Entry
| Organism name | Vicia spp. |
|---|---|
| Genus | Vicia |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Vicia |
|---|---|
| Linked NCBI taxonomy ID | 3904 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006729
|
Petunidin 3-rhamnoside-5-glucoside
|
No. 1 | No. 15 |
|
||||
|
C00006728
|
Petunin
/ Petunidin 3,5-di-O-beta-D-glucoside |
No. 1 | No. 15 |
|
||||
|
C00005428
|
Quercetin 3-glucoside-7-rhamnoside
/ Quercetin 3-O-glucoside-7-O-rhamnoside / Quercetin 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside |
CHEMBL592361
CHEMBL1774171 |
No. 1 | No. 15 |
|
|||
|
C00005226
|
Robinin
|
C005183
|
1 / 0 | No. 5 | No. 15 |
|
||
|
C00001369
|
(+)-gamma-Hydroxy-L-homoarginine
|
No. 1782 |
|
|||||
|
C00001368
|
gamma-Hydroxy-L-arginine
|
No. 1782 |
|
|||||
|
C00001337
|
gamma-Aminobutyric acid
|
CHEMBL96
|
D005680
|
50 / 36 / 27 | 21 / 17 | No. 3932 |
|
Human Protein / Gene in interactions
50 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P48066 | Sodium- and chloride-dependent GABA transporter 3 | GABA | C00001337 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001337 | 1 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001337 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001337 | 2 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001337 | 0 / 0 |
| P30531 | Sodium- and chloride-dependent GABA transporter 1 | GABA | C00001337 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001337 | 11 / 10 |
| P23415 | Glycine receptor subunit alpha-1 | GLR alpha | C00001337 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001337 | 3 / 2 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001337 | 3 / 1 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00001337 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001337 | 0 / 1 |
| P24046 | Gamma-aminobutyric acid receptor subunit rho-1 | GABA-A rho | C00001337 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00001337 | 1 / 2 |
| P48065 | Sodium- and chloride-dependent betaine transporter | Betaine and GABA Na-symporter | C00001337 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001337 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001337 | 0 / 0 |
| P46098 | 5-hydroxytryptamine receptor 3A | NS | C00001337 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00001337 | 1 / 2 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001337 | 1 / 2 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00001337 | 1 / 1 |
| Q9UBS5 | Gamma-aminobutyric acid type B receptor subunit 1 | GABA-B receptor | C00001337 | 0 / 0 |
| P36544 | Neuronal acetylcholine receptor subunit alpha-7 | CHRN alpha | C00001337 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001337 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001337 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001337 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001337 | 0 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00001337 | 1 / 0 |
| Q7Z2H8 | Proton-coupled amino acid transporter 1 | Unclassified protein | C00001337 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001337 | 0 / 0 |
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00001337 | 0 / 0 |
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00001337 | 1 / 0 |
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00001337 | 0 / 0 |
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00001337 | 1 / 1 |
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00001337 | 0 / 0 |
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00001337 | 0 / 0 |
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00001337 | 0 / 0 |
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00001337 | 0 / 0 |
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00001337 | 0 / 0 |
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00001337 | 0 / 0 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00001337 | 0 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00001337 | 4 / 2 |
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00001337 | 0 / 0 |
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00001337 | 0 / 0 |
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00001337 | 1 / 0 |
| A8MPY1 | Gamma-aminobutyric acid receptor subunit rho-3 | GABA-A rho | C00001337 | 0 / 0 |
| P28476 | Gamma-aminobutyric acid receptor subunit rho-2 | GABA-A rho | C00001337 | 0 / 0 |
| Q05BR4 | SLC16A10 protein | Unclassified protein | C00001337 | 0 / 0 |
| O75899 | Gamma-aminobutyric acid type B receptor subunit 2 | GABA-B receptor | C00001337 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001337 | 1 / 1 |
22 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00005226
|
| 18 | ABAT, GABA-AT, GABAT, NPD009 | 4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22) |
C00001337
|
| 1138 | CHRNA5, LNCR2 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
C00001337
|
| 1140 | CHRNB1, ACHRB, CHRNB, CMS1D, CMS2A, SCCMS | cholinergic receptor, nicotinic, beta 1 (muscle) |
C00001337
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00001337
|
| 2550 | GABBR1, GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2 | gamma-aminobutyric acid (GABA) B receptor, 1 |
C00001337
|
| 9568 | GABBR2, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099 | gamma-aminobutyric acid (GABA) B receptor, 2 |
C00001337
|
| 2554 | GABRA1, ECA4, EJM, EJM5 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
C00001337
|
| 2555 | GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
C00001337
|
| 2557 | GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
C00001337
|
| 2558 | GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
C00001337
|
| 2559 | GABRA6 | gamma-aminobutyric acid (GABA) A receptor, alpha 6 |
C00001337
|
| 2560 | GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 |
C00001337
|
| 2561 | GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
C00001337
|
| 2562 | GABRB3, ECA5 | gamma-aminobutyric acid (GABA) A receptor, beta 3 |
C00001337
|
| 2563 | GABRD, EIG10, EJM7, GEFSP5 | gamma-aminobutyric acid (GABA) A receptor, delta |
C00001337
|
| 2564 | GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon |
C00001337
|
| 2566 | GABRG2, CAE2, ECA2, GEFSP3 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
C00001337
|
| 2571 | GAD1, CPSQ1, GAD, SCP | glutamate decarboxylase 1 (brain, 67kDa) (EC:4.1.1.15) |
C00001337
|
| 6529 | SLC6A1, GABATHG, GABATR, GAT1 | solute carrier family 6 (neurotransmitter transporter), member 1 |
C00001337
|
| 6538 | SLC6A11, GAT-3, GAT3, GAT4 | solute carrier family 6 (neurotransmitter transporter), member 11 |
C00001337
|
| 6540 | SLC6A13, GAT-2, GAT2, GAT3 | solute carrier family 6 (neurotransmitter transporter), member 13 |
C00001337
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (36)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103780 | Alcohol dependence |
P47869
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #607208 | Dravet syndrome |
P18507
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #149400 | Hyperekplexia, hereditary 1; hkpx1 |
P23415
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (27)
| KEGG | name | UniProt |
|---|---|---|
| H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00769 | Hyperekplexia |
P23415
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
Diseases related to CTD interactions
17 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001259 | Ataxia |
C00001337
|
| D001919 | Bradycardia |
C00001337
|
| D002375 | Catalepsy |
C00001337
|
| D002389 | Catatonia |
C00001337
|
| D019970 | Cocaine-Related Disorders |
C00001337
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00001337
|
| D004827 | Epilepsy |
C00001337
|
| D006429 | Hemiplegia |
C00001337
|
| D006973 | Hypertension |
C00001337
|
| D007022 | Hypotension |
C00001337
|
| D020149 | Manganese Poisoning |
C00001337
|
| D009069 | Movement Disorders |
C00001337
|
| D012559 | Schizophrenia |
C00001337
|
| D012640 | Seizures |
C00001337
|
| D013226 | Status Epilepticus |
C00001337
|
| D013375 | Substance Withdrawal Syndrome |
C00001337
|
| D013610 | Tachycardia |
C00001337
|