| class name | count |
|---|---|
| rosids | 9 |
| asterids | 1 |
| class name | count |
|---|---|
| Fabaceae | 8 |
| Solanaceae | 1 |
| Enterobacteriaceae | 1 |
| Brassicaceae | 1 |
| Bacillaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001340
|
L-Arginine
|
CHEMBL212301
CHEMBL1485 |
22 / 12 / 16 |
|
||
|
C00001364
|
L-Homoarginine
|
CHEMBL589752
|
3 / 3 / 1 |
|
||
|
C00001368
|
gamma-Hydroxy-L-arginine
|
|
||||
|
C00001369
|
(+)-gamma-Hydroxy-L-homoarginine
|
|
||||
|
C00017959
|
N5-Hydroxy-L-arginine
/ delta-N-Hydroxy-L-arginine |
|
||||
|
C00040829
|
4-Hydroxyarginine
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P29475 | Nitric oxide synthase, brain | Enzyme | C00001340 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001340 | 1 / 0 |
| Q9Y263 | Phospholipase A-2-activating protein | Unclassified protein | C00001364 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001340 | 3 / 2 |
| Q15661 | Tryptase alpha/beta-1 | S1A | C00001340 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001340 | 0 / 1 |
| O94760 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | Enzyme | C00001340 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001340 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00001364 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00001364 | 3 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001340 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00001340 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001340 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001340 | 0 / 0 |
| P29474 | Nitric oxide synthase, endothelial | Enzyme | C00001340 | 0 / 0 |
| P35228 | Nitric oxide synthase, inducible | Enzyme | C00001340 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001340 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001340 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001340 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001340 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001340 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001340 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001340 | 1 / 2 |
| Q9H015 | Solute carrier family 22 member 4 | Unclassified protein | C00001340 | 1 / 1 |
| O76082 | Solute carrier family 22 member 5 | Unclassified protein | C00001340 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #212140 | Carnitine deficiency, systemic primary; cdsp |
O76082
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #301500 | Fabry disease |
P06280
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #611162 | Malaria, susceptibility to |
P35228
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #180300 | Rheumatoid arthritis; ra |
Q9H015
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00286 | Crohn's disease |
O76082
(related)
Q9H015 (related) |
| H00525 | Disorders of fatty-acid oxidation |
O76082
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35228
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|