Plant Species


Cumulative plant class count

class name count
rosids 9
asterids 1

Cumulative family count

class name count
Fabaceae 8
Solanaceae 1
Enterobacteriaceae 1
Brassicaceae 1
Bacillaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001340 External link 512 L-Arginine
CHEMBL212301
CHEMBL1485
22 / 12 / 16
C00001364 External link 512 L-Homoarginine
CHEMBL589752
3 / 3 / 1
C00001368 External link 512 gamma-Hydroxy-L-arginine
C00001369 External link 512 (+)-gamma-Hydroxy-L-homoarginine
C00017959 External link 512 N5-Hydroxy-L-arginine
/ delta-N-Hydroxy-L-arginine
C00040829 External link 512 4-Hydroxyarginine

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P29475 Nitric oxide synthase, brain Enzyme C00001340 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001340 1 / 0
Q9Y263 Phospholipase A-2-activating protein Unclassified protein C00001364 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001340 3 / 2
Q15661 Tryptase alpha/beta-1 S1A C00001340 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001340 0 / 1
O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 Enzyme C00001340 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001340 0 / 0
P09923 Intestinal-type alkaline phosphatase Enzyme C00001364 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00001364 3 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00001340 0 / 0
P06280 Alpha-galactosidase A Enzyme C00001340 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001340 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00001340 0 / 0
P29474 Nitric oxide synthase, endothelial Enzyme C00001340 0 / 0
P35228 Nitric oxide synthase, inducible Enzyme C00001340 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001340 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001340 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00001340 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001340 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001340 0 / 0
O00255 Menin Unclassified protein C00001340 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001340 1 / 2
Q9H015 Solute carrier family 22 member 4 Unclassified protein C00001340 1 / 1
O76082 Solute carrier family 22 member 5 Unclassified protein C00001340 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#212140 Carnitine deficiency, systemic primary; cdsp O76082
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#301500 Fabry disease P06280
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#611162 Malaria, susceptibility to P35228
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#180300 Rheumatoid arthritis; ra Q9H015

KEGG DISEASE (17)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00286 Crohn's disease O76082 (related)
Q9H015 (related)
H00525 Disorders of fatty-acid oxidation O76082 (related)
H00213 Hypophosphatasia P05186 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00017 Esophageal cancer P35228 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)