PCIDB

KNApSAcK Metabolite C00001340

Metabolite

KNApSAcK Entry

id C00001340
Name L-Arginine
CAS RN 74-79-3
Standard InChI InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
Standard InChI (Main Layer) InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)

Cluster

Phytochemical cluster
KCF-S cluster No. 1782

Link

ChEMBL

By standard InChI CHEMBL1485
By standard InChI Main Layer CHEMBL212301 CHEMBL1485

KEGG

By LinkDB C00062

CTD

By CAS RN

Human Protein / Gene in interaction

22 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P29475 Nitric oxide synthase, brain Enzyme CHEMBL1485 CHEMBL859444 (1) CHEMBL755144 (1)
0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1485 CHEMBL1741321 (1)
1 / 0
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL1485 CHEMBL1614361 (1)
3 / 2
Q15661 Tryptase alpha/beta-1 S1A CHEMBL1485 CHEMBL832048 (1)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1485 CHEMBL1741325 (1)
0 / 1
O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 Enzyme CHEMBL1485 CHEMBL981884 (2) CHEMBL981890 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL1485 CHEMBL1794486 (1)
0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1485 CHEMBL1738610 (1)
0 / 0
P06280 Alpha-galactosidase A Enzyme CHEMBL1485 CHEMBL1614217 (1)
1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1485 CHEMBL1741322 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL1485 CHEMBL1614274 (1) CHEMBL1613823 (1)
0 / 0
P29474 Nitric oxide synthase, endothelial Enzyme CHEMBL1485 CHEMBL679387 (1) CHEMBL679388 (1)
0 / 0
P35228 Nitric oxide synthase, inducible Enzyme CHEMBL1485 CHEMBL702711 (1) CHEMBL696862 (1)
CHEMBL933386 (1) CHEMBL996087 (1)
CHEMBL955234 (1) CHEMBL955235 (1)
1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1485 CHEMBL1613777 (1) CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1485 CHEMBL1741324 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1485 CHEMBL1794483 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL1485 CHEMBL1614283 (1) CHEMBL1614211 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL1485 CHEMBL1738442 (2)
0 / 0
O00255 Menin Unclassified protein CHEMBL212301 CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL212301 CHEMBL1614531 (1)
1 / 3
Q9H015 Solute carrier family 22 member 4 Unclassified protein CHEMBL1485 CHEMBL2076170 (1)
1 / 1
O76082 Solute carrier family 22 member 5 Unclassified protein CHEMBL1485 CHEMBL2077730 (1)
1 / 2

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#212140 Carnitine deficiency, systemic primary; cdsp O76082
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#301500 Fabry disease P06280
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#611162 Malaria, susceptibility to P35228
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#180300 Rheumatoid arthritis; ra Q9H015

KEGG DISEASE (16)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00286 Crohn's disease O76082 (related)
Q9H015 (related)
H00525 Disorders of fatty-acid oxidation O76082 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00017 Esophageal cancer P35228 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)